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Acema (Tramadol)

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Acema is a pain medicine similar to an opioid. It acts in the central nervous system (CNS) to relieve pain. Acema is used to treat moderate to severe pain in adults. The extended-release form of Acema is for around-the-clock treatment of pain. This form of Acema is not for use on an as-needed basis for pain.

Other names for this medication:
Accupain, Acema, Adamon, Anatram, Bestodol, Bolodol, Cadol, Cradol, Damadol, Dolriz, Drobit, Omodol, Opigesic, Redimol, Supridol, Tradol, Tramacon, Tramaflam, Trambax, Tramex, Trandy, Transic, Trapidol, Trectadol, Trofel, Tromar, Trugesic, Typhon, Ubitdol, Ultraspas

Similar Products:
Feldene, Lasix, Amoxil, Pepcid, Zyloprim, Crestor, Zovirax

Also known as: Tramadol


{name} (tramadol) is a pain medicine similar to an opioid. It acts in the central nervous system (CNS) to relieve pain.

{name} is used to treat moderate to severe pain in adults.

The extended-release form of tramadol ({name} ER) is for around-the-clock treatment of pain. {name} ER is not for use on an as-needed basis for pain.


Follow the directions on your prescription label and read all medication guides. Never use Acema ER in larger amounts, or for longer than prescribed. Tell your doctor if you feel an increased urge to take more of Acema ER.

Never share Acema ER with another person, especially someone with a history of drug addiction. MISUSE CAN CAUSE ADDICTION, OVERDOSE, OR DEATH. Keep the medicine where others cannot get to it. Selling or giving away this medicine is against the law.

Stop taking all other opioid medications when you start taking Acema ER.

Acema ER can be taken with or without food, but take it the same way each time.

Swallow the capsule or tablet whole to avoid exposure to a potentially fatal overdose. Do not crush, chew, break, open, or dissolve.

Measure liquid medicine with the supplied syringe or a dose-measuring device (not a kitchen spoon).

Never crush or break a Acema ER pill to inhale the powder or mix it into a liquid to inject the drug into your vein. This practice has resulted in death.

You may have withdrawal symptoms if you stop using Acema ER suddenly. Ask your doctor before stopping the medicine.

Store at room temperature away from moisture and heat. Keep track of your medicine. You should be aware if anyone is using it improperly or without a prescription.

Do not keep leftover Acema ER. Just one dose can cause death in someone using it accidentally or improperly. Ask your pharmacist where to locate a drug take-back disposal program. If there is no take-back program, mix the leftover medicine with cat litter or coffee grounds in a sealed plastic bag throw the bag in the trash.

Detailed Acema ER dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose can be fatal, especially in a child or other person using the medicine without a prescription. Overdose symptoms may include severe drowsiness, pinpoint pupils, slow breathing, or no breathing.

Your doctor may recommend you get naloxone (a medicine to reverse an opioid overdose) and keep it with you at all times. A person caring for you can give the naloxone if you stop breathing or don't wake up. Your caregiver must still get emergency medical help and may need to perform CPR (cardiopulmonary resuscitation) on you while waiting for help to arrive.

Anyone can buy naloxone from a pharmacy or local health department. Make sure any person caring for you knows where you keep naloxone and how to use it.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Detailed Acema dosage information

Side effects

The most common side effects associated with Acema are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not drink alcohol. Dangerous side effects or death could occur.

Avoid driving or hazardous activity until you know how this medicine will affect you. Dizziness or drowsiness can cause falls, accidents, or severe injuries.

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Plasma 8-isoprostane concentrations in patients with age-related cataracts. This finding did not result from uniform antibody responses across subjects, as controllers could be regrouped according to strong differences in their HIV-specific antibody subclass specificity profiles. Mitotic effect of radix codonopsis pilosulae, radix astragali and semen strychni on human lymphocytes. It raises the fascinating question of the role of REM sleep and of dreaming in the evolution of the organism and of the species. We have prepared cytosols of normal breast tissue and breast tumour tissue and examined their effect on 17 beta-oestradiol dehydrogenase (E2DH) activity in cultured normal breast fibroblasts and on the MCF-7 breast cancer cell line. Age groups (juveniles and adults) differed in 10 of the 18 analytes measured, including protein levels and albumin/globulin ratio, aspartate aminotransferase, alkaline phosphatase, creatine kinase, creatinine, phosphorus, calcium and potassium. While the direction and magnitude of effects associated with a given preanalytical factor were dependent on the analyte (DNA, RNA, protein, and morphology) and analytical platform, acceptable conditions are highlighted, and a summary of conditions that could preclude analysis is provided. All patients underwent high-precision stereotactic radiosurgery using a linear accelerator with 6-MV photons. The flat-panel prototype provides better definition of fine osseous structures of temporal bone than that of currently available MSCT scanners.

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Analysis of the cytokine profile demonstrated that hsp60-reactive PBMC produced significant levels of gamma interferon (IFN-gamma) in periodontitis patients, whereas P. We are drawing from genomics, transcription and translation analysis at different levels, to improve our knowledge of the molecular alterations along the pathways which are activated during carcinogenesis and tumor progression. Controlling pH value, adding nutrient and optimizing the quantity of inducer during cultivation, the activity of nitrile hydratase reached 6567 u/mL (culture medium), which was the highest value appeared in native journals. Obstructive sleep apnea syndrome in a pubescent boy of short stature was improved with an orthodontic mandibular advancement oral appliance: a case report. Predictive genetic testing - change in paradigms for prevention and health care?. aureus remained the predominant pathogen in community-acquired SSTIs, ED clinicians did not accurately target therapy toward the causative pathogen. We evaluated rapmad in antibody reactivity experiments for several thousand peptide spots and compared it to two existing algorithms for the analysis of peptide microarrays. Autoerotic death: incidence and age of victims--a population-based study.

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Bridging peripheral nerves using a deacetyl chitin conduit combined with short-term electrical stimulation. Agglutinogen 2 (AGG2) of Bordetella pertussis is a fimbrial antigen and therefore a potential adhesin and acellular vaccine component. The mean periods of elimination on which withholding times are based were between four and seven milkings according to the drugs administered. Both incidence of Multiple Sclerosis in Catania and volcanic activity of Mount Etna have been significantly increased during the last 30 years. Compared with WKY neurons, SH neurons had higher firing rates in the preoptic-anterior hypothalamus and lower firing rates in the dorsomedial hypothalamus.

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Recent studies have evaluated intratumoral heterogeneity within the primary tumor, as well as heterogeneity observed between primary and metastasis. Questionnaires, anthropometric measurements, and fasting blood samples were collected, and the participants were assessed by a rheumatologist at baseline and at the end of the trial. In addition, ADRs due to inappropriate medication use occur often in the real world of clinical practice but not in RCTs. These phenomena were especially remarkable at the maximum elevation of the arm. Positive cases were compared with negative cases concerning epidemiological data, risk factors, clinical presentation and laboratory parameters, with emphasis on changes in the differential blood count. The incidence in the eastern coastal areas (217.77/100 000(286 300/131 468 746)) including Ningbo, Taizhou, Wenzhou, was higher than the western mountain areas(168.11/100 000(98 016/58 304 266)) including Quzhou, Lishui, Jinhua. We determine how changes in price and purity of methamphetamine compared to other drugs such as heroin may, in part, explain these divergent patterns. Several isoforms of the gap junction protein connexin (Cx) have been identified in a variety of tissues that communicate intercellular signals between adjacent cells. Gene co-expression was determined with Pearson correlation coefficient.

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We identified and reviewed 26 suitable publications representing 20 separate cohorts, of which 16 had a term control group. Patients received ten treatments with a 1550 nm fractional Er:Glass Laser (Mosaic, Lutronic Co., Ltd, Seoul, South Korea) at 2-weeks intervals using the same parameters (5-10 mm tip, 6 mJ pulse energy, 800 spot/cm(2) density, static mode). Forearm venous tone was measured throughout pregnancy in 68 nulliparous women thought to be at high risk of the development of gestational hypertension. The effects of clonidine on the response of the guinea-pig urinary bladder detrusor muscle to stimulation of non-adrenergic non-cholinergic (NANC) nerves were investigated in-vitro. This article details an audit of the supply of medications by specialist nurses at a genitourinary medicine clinic. We retrospectively reviewed the medical records of UC patients who were registered and followed up at the Asan Medical Center. Fine needle aspiration: past, current practice and recent developments. The neoplasm has a low malignant potential with only 1 patient known to have had metastasis.

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Amino acid changes in the influenza A virus PA protein that attenuate avian H5N1 viruses in mammals. This article will review the published literature on pharmacotherapy of seasonal affective disorder. New treatments are rarely cost effective, and, in the absence of a comprehensive economic assessment, continued use for high risk infants may appear justified. When given in daily milligram amounts to postmenopausal women, exemestane almost totally blocks peripheral aromatase and reduces circulating estrogens to levels that are at the limit of detection of current assays. We investigated serum and synovial fluid (SF) concentrations of MMP-3 and its tissue inhibitor (TIMP-1) in juvenile idiopathic arthritides (JIA). Chloride--bicarbonate exchange in red blood cells: physiology of transport and chemical modification of binding sites. The goal of these guidelines is to encourage transparent and complete reporting so that the relevant information will be available to others to help them to judge the usefulness of the data and understand the context in which the conclusions apply.

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Role of human neutrophil gelatinase associated lipocalin (NGAL) and Matrix Metalloproteinase-9 (MMP-9) overexpression in neoplastic colon polyps. From the relationships, we can find that the T-fuzzy rough set model is a special instance of the two new types of models. Although most of this work has not been motivated by the reality of terrorism or, in particular, by the attacks of 9/11, much of it is relevant to one or another aspect of terrorism in its various manifestations flomax generic name and brand name , and human factors and ergonomics researchers are increasingly making the connection. Insights into role of the hydrogen bond networks in substrate recognition by UDP-GalNAc 4-epimerases. The results of this study demonstrated that CORAGRAF is a good implant material that can accelerates bone healing and be resorbed in an acceptable time.

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Using site-directed point mutations in two conserved motifs, glycine, lysine and valine/threonine (GKV/T) at positions 181-183 and tyrosine and leucine (YL) at positions 412-413, and an assay to measure the reversal of gene silencing in Nicotiana benthamiana line 16c, we show that substitutions (K182 to A, and L413 to A) in these motifs abolished suppressor activity of the NSs protein, indicating that these two motifs are essential for the RNAi suppressor glucophage generic drug function of tospoviruses. Traditional Iranian medicine (TIM) is a main part of complementary and alternative medicine (CAM). Although the employment rate for the group of haemophiliacs is lower than that for the general male population, the level of employment in relation to educational achievements is high and most of the employed do not feel limited in their daily job activities by the haemophilia. Many diseases are related to S100 proteins, which function as new biochemical markers especially in cardiac diseases. Specimens for SEM were harvested after heparinization but before institution of cardiopulmonary bypass from the terminal branches of both IMAs after they had been skeletonized with either mobilization method.

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Of particular interest, the product distributions were found to depend on the counter cations of Nafion. Reverse reaction of Aspergillus niger APC-9319 alpha-galactosidase in a supersaturated substrate solution: production of alpha-linked galactooligosaccharide (alpha-GOS). Physical activity and dietary fat consumption were inversely related among African-American girls. Emerging treatments, such as ultra-low-dose vaginal estradiol tablets, new selective estrogen receptor modulators (SERMs), and intravaginal dehydroepiandrosterone (DHEA) are other promising options for postmenopausal women with vaginal atrophy and sexual dysfunction. To examine this question, male Wistar rats were treated with tamoxifen (0.1 mg/rat/day or 1.0 mg/rat/day) or vehicle for three days prior to and after partial hepatectomy, and the anatomic and biochemical process of hepatic regeneration was assessed. However, secondary prevention exercise and education programmes warrant further research with regards to their effects on perceptions of mental health in this population group. Furthermore, the change cosegregates with the disease in all affected members of the family, not being present in 80 control chromosomes. Western blot and specific immunoglobulin-G rocaltrol tablet uses in hindi antibody were used to identify the urinary NMP marker.

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Preferential inhibition of penicillinase induction by oxytetracycline and its effect on the penicillin susceptibility of staphylococci. Carotid artery intima media thickness (CIMT) was measured by high resolution B mode ultrasonography. Lipoprotein profile in long term theophylline administration in children with asthma. A total of 112 IVF patients in whom estradiol levels fell prior to the administration of hCG were matched for age and year of treatment with 112 control IVF patients. To perform amiloride hcl dosage a retrospective, anesthesia case note review of patients with Fraser syndrome.

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We found no evidence of DNA from parvovirus B19, human herpes virus or C. We used three-dimensional power Doppler angiography (3D-PDA) to examine the periodic changes in endometrial development and subendometrial vascularity during the normal menstrual cycle in 29 women with unexplained subfertility and 19 controls. This study used fMRI to compare VS structure and function of 30 participants with ADHD-CT (16 adults, 14 children) and 30 controls (20 adults, 10 children), using a monetary incentive delay task. However, it has become increasingly clear that they also play important roles in diverse physiological and pathological processes. All patients treated with lithium in Denmark, ie, within community psychiatry, private specialist practice settings, and general practice.

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In collagen-stimulated samples, MK-852 accelerated clotting but delayed completion of clotting while abciximab prolonged both clotting time and completion of clotting. We introduce deML, a maximum likelihood algorithm that demultiplexes Illumina sequences. The lymphocytic infiltrate in both the lobular and portal spaces was characterized by a relative increase of cytotoxic/suppressor (T8) cozaar generic name canada cells. Chart review was carried out to obtain medical history, smoking status, radiological appearance, and histology of lung lesions biopsied. Glenohumeral displacements were measured from trajectories of reflective markers fitted on intracortical pins inserted into the scapula and humerus. Formation parameter estimation methods based on measurements of pressure in horizontal wells have been presented in the petroleum industry literature, but these methods have limited applicability for ground water evaluation and are based on pressure measurements in only the horizontal well borehole, rather than in observation wells. Urethrogluteal fistula developing secondary to the use of clean intermittent self-catheterization: first case report in the literature. Participants with autism showed a reduced tendency to reproduce those actions which were relatively inefficient to reach the goals.

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Development and interactions of Trypanosoma cruzi within the insect vector. Smaller brachial FMD values are associated with higher rates of AF, suggesting a role for endothelial dysfunction in AF pathogenesis. Our results show a linear relationship between threshold current and pulse width. Case history of a patient treated at the Accident Hospital, Birmingham. Importantly, the invasion capacity of Espin-depleted Mel-ret melanoma cells derived from a tumor of the RET-mouse was dramatically less than that of control melanoma cells with reductions of lamellipodia, focal adhesion kinase (FAK), and GTP-Rac1 activities. A survey of Polish malt and beer for volatile N-nitrosamines has been conducted. Effects of anesthesia and vehicle injection on circulating blood elements in C3H/HeN male mice.

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