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Acraz (Acarbose)
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Acraz

Acraz is a complex oligosaccharide that competitively inhibits the ability of brush-border alpha-glucosidase enzymes to break down ingested carbohydrates into absorbable monosaccharides, reducing carbohydrate absorption and subsequent postprandial insulin levels.

Other names for this medication:
Abacus, Acarb, Acarbose, Acarex, Acarwin, Acraz, Asucrose, Diabose, Discarb, Disorb, Exforge, Glubose, Glucar, Glucarb, Glucobay, Glucobose, Gludase, Hebose, Olcarbos, Prandase, Rebose, Recarb, Subase, Zebay, Zebose

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Also known as: Acarbose

Description

Generic Acraz is used for treating type 2 diabetes in adults whose diabetes cannot be managed with diet alone. Generic Acraz may be used alone, in combination with other oral diabetes medicines, or with insulin. Generic Acraz is a glucosidase inhibitor. It works by slowing down the enzyme that turns carbohydrates into glucose; it decreases blood sugar levels following a meal. Acraz is also known as Acarbose, Glucobay, Glucor, Rebose. Generic name of Generic Acraz is Acarbose. Brand name of Generic Acraz is Acraz.

Dosage

Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.

Take Acraz with the first bite of a main meal, unless your doctor tells you otherwise.

Your blood sugar will need to be checked often, and you may need other blood tests at your doctor's office.

If you take Acraz with insulin or other diabetes medications, your blood sugar could get too low.

Low blood sugar (hypoglycemia) can happen to everyone who has diabetes. Symptoms include headache, hunger, sweating, confusion, irritability, dizziness, or feeling shaky. Always keep a source of dextrose (D-glucose) with you in case you have low blood sugar. When taking Acraz, dextrose will work better than cane sugar or table sugar in treating hypoglycemia. Sources of dextrose include honey, dates, raisins, plums, dried prunes, grapes, or glucose tablets. Be sure your family and close friends know how to help you in an emergency.

If you have severe hypoglycemia and cannot eat or drink, use a glucagon injection. Your doctor can prescribe a glucagon emergency injection kit and tell you how to use it.

Also watch for signs of high blood sugar (hyperglycemia) such as increased thirst, increased urination, hunger, dry mouth, fruity breath odor, drowsiness, dry skin, blurred vision, and weight loss.

Check your blood sugar carefully during times of stress, travel, illness, surgery or medical emergency, vigorous exercise, or if you drink alcohol or skip meals. These things can affect your glucose levels and your dose needs may also change. Do not change your medication dose or schedule without your doctor's advice.

Acraz is only part of a complete treatment program that may also include diet, exercise, weight control, regular blood sugar testing, and special medical care. Follow your doctor's instructions very closely.

Store at room temperature away from moisture and heat. Keep the bottle tightly closed when not in use.

Detailed Acraz dosage information

Overdose

If you overdose Generic Acraz and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Store at room temperature below 25 degrees C (77 degrees F) away from moisture and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Acraz are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

You should not use Acraz if you are allergic to it, or if you have:

inflammatory bowel disease; a blockage in your intestines; a digestive disorder affecting your intestines; intestinal ulcer (of your colon); cirrhosis of the liver; or diabetic ketoacidosis (call your doctor for treatment with insulin).

To make sure Acraz is safe for you, tell your doctor if you have:

liver disease; kidney disease; a bowel or intestinal disorder; or a stomach disorder.

Acraz is not expected to harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

It is not known whether acarbose passes into breast milk or if it could harm a nursing baby. You should not breast-feed while you are using acarbose.

Acraz is not approved for use by anyone younger than 18 years old.

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Several areas of use of this echoendoscope are yet to be better defined, such as its potential for therapeutic and interventional procedures, as well as for natural orifice transluminal endoscopic surgery. Besides a preferential expression in prostate for all targets, striking differences in the expression levels and TSI were revealed which may be important for the selection of appropriate antigens for immunotherapy of PCa. For this miner, the absorbed dose to the central regions of the lung is dominated by the dose arising from exposure to radon progeny, whereas the absorbed dose to the red bone marrow is dominated by the external gamma dose. It may represent a rare, unusual, early component of the disease or a clinical manifestation secondarily related to the typical APS 1 components (i.e. EDG ISR constitutes a specific subgroup with relevant therapeutic implications. In addition, we review the literature on the genetics of deafness in SSA.

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The resulting functionalised graphene was characterised by Raman spectroscopy, TGA, XPS, AFM, and dispersibility tests in organic or aqueous media. Running with the Red Queen: the role of biotic conflicts in evolution. Germin is a water soluble homopentameric glycoprotein which is remarkable resistant to degradation by a broad range of proteases including pepsin. We review recent studies on the glial identity of stem cells that generate new neurons, the different modes of migration used by the newly generated neurons to reach their destinations, and how these systems respond to experimentally induced cell death. In young men, testosterone secretion peaks during sleep and is linked to sleep architecture. The high degree of uncertainty, caused at least in part by large vehicle-to-vehicle variation, may obscure the true PM response and adversely impact attainment of increasingly more stringent diesel PM emissions standards in the United States.

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Therefore, it has become the most important imaging technique to evaluate valular function. Induction of HM1.24 peptide-specific cytotoxic T lymphocytes by using peripheral-blood stem-cell harvests in patients with multiple myeloma. Patients with the greatest odds of long LOS were women with asthma or coronary disease, men with sleep apnea or the metabolic syndrome, and patients undergoing laparoscopic surgery with sleep apnea or coronary artery disease. The rapid worldwide spread of severe acute respiratory syndrome demonstrated the potential threat an infectious disease poses in a closely interconnected and interdependent world. There is an intense search underway for individual functions of these enzymes and for selective histone deacetylase inhibitors (HDACi). The exposure of the mesoporous films to high energy X-rays, which are generated by a synchrotron source, produces several effects: the removal of the surfactant, the densification of the silica backbone and the formation of silver nanoparticles. However, the significance of PIK3CA gene alterations with respect to clinicopathological characteristics, and in particular tumor recurrence and progression, remains elusive. The influence of angular deformity of the scaphoid on wrist function and arthrosis is debated and the reliability of the described quantitative measurements of deformity has been questioned. In this mini-review, we evaluate the main methods described for measuring the different kinds of PDI activity: thiol reductase, thiol oxidase, thiol isomerase and chaperone. Intra-abdominal fat (IAF) and subcutaneous fat (SQF) were measured at the level of lumbar 2-3 and 4-5 spaces, using EBCT.

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Nationwide Inpatient Sample data collected between 2001 and 2010 were analyzed. Calculated long-term survival curves demonstrated similar survival in both age groups, with approximately 65 percent of hospital survivors alive at 24 months after hospital discharge. The antihypertensive and vasorelaxant effects of water-soluble proanthocyanidins, extracted in persimmon leaf tea, were investigated in spontaneously hypertensive rats, rat aortas, and human umbilical vein endothelial cells. The canonical Wnt pathway is involved in cell proliferation, differentiation and migration, especially during nervous system development. At days 34-41, 2-mm2 sheets of hepatocyte-like cells were cut out of their colonies by scratching with an injection needle under observation with a phase contrast microscope, transferred into wells of 24-well plates, and cultured in the HGM medium in the presence or absence of HGF and EGF. Ischemia and reperfusion cause mitochondrial dysfunctions that initiate the mitochondrial apoptosis pathway. In the present study, we demonstrated that Lin28 was highly expressed in mesenchymal (M) type cells (MDA-MB-231 and SK-3rd), but it was barely detectable in epithelial (E) type cells (MCF-7 and BT-474). Furthermore the differences between fetal and adult erythrocytes were more pronounced than those between neonatal and adult cells. Doppler ultrasonography can be used to assess the vascular resistance in small renal intraparenchymal vessels through analysis of the Doppler waveform by a parameter termed Resistive Index (RI). In general, absolute prediction errors were significantly smaller for regression based on these regions compared with PLR and NM sectors.

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Newly developed stenocardia: electrocardiographic and angiographic comparisons and the possibility of conducting intraluminal dilatation of coronary arteries. Factors in the prevention of cardio-vascular diseases--Part 1: 96 cardio-vascular risk factors, with special emphasis on the prevention and treatment of hypertension, controllable dietary risk factors, and recommended U.S. Effects of localized freezing of a peripheral nerve on the conduction of the nerve-impulse, during degeneration and regeneration. Similar changes were observed in neurones where the Na/K-ATPase was blocked by ouabain. Isoflavones: chemistry, analysis, functions and effects on health and cancer.

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Endodontic filling removal procedure: an ex vivo comparative study between two rotary techniques. This study was done to compare the prevalence of changes in bone mineral parameters and bone mineral density (BMD) in ambulant individuals on long-term anticonvulsant therapy with age- and body mass index (BMI)-matched healthy controls. Tunable, luminescent, and self-healing hybrid hydrogels of polyoxometalates and triblock copolymers based on electrostatic assembly. Thus, the p38 MAP kinase pathway appears to be a major component of Smad-independent signaling by TGF-beta and may provide a new molecular target for anti-osteolytic therapy. In chickens, the kidney possesses a distinct cytosolic phosphoenolpyruvate carboxykinase activity which is not found in the liver. Multilayered genetic and omics dissection of mitochondrial activity in a mouse reference population. Early recognition of the signs of MH provides the clinical diagnostic clues. In this study, the eight furoquinoline alkaloids were examined for inhibitory potency against human phosphodiesterase 5 (hPDE5A) in vitro.

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Ultrafast cooling instituted by TLV exerts potent neurological and cardiac protection in an experimental model of cardiac arrest in rabbits. Finally, associations with cell death and CD95 receptors suggest that TNF may be pathogenic in SLE. Most of the families are basically suffering from severe psychosocial problems eg drug abuse and at least one of the parents is HIV-infected. Soluble urokinase-type plasminogen activator receptor: a useful biomarker for coronary artery disease and clinical outcomes?. The profiles were obtained for particular individuals clustered in PCA and were experimentally separable from other individuals in most cases. We determined whether the patients had metabolic syndrome and insulin resistance at diagnosis, and recorded known prognostic factors, such as tumor size, axillary lymph node involvement, presence of distant metastasis, tumor grade, estrogen receptor (ER), progesterone receptor (PR), and CerbB-2 status.

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Inositol polyphosphates containing an energetic pyrophosphate bond are formed primarily by a family of three inositol hexakisphosphate (IP6) kinases (IP6K1-3). The use of simvastatin as prophylaxis against delayed cerebral ischemia after aneurysmal SAH is a safe and well-tolerated intervention. We aimed to assess the potential usefulness of primary care data in the UK for estimating smoking prevalence in pregnancy by comparing the primary care data estimates with those obtained from other data sources. We use simulation to compare two alternative tests which may be undertaken to determine whether models for multisite capture-recapture data need to incorporate memory. Tissue factor (TF) mRNA levels in leukocyte and TF antigen in plasma were examined in patients with deep vein thrombosis (DVT). In this study, two numerical models are used to simulate the dispersion pattern of fine suspended sediment spilled from a dredge barge, considering different hydrodynamic scenarios, particle sizes and dredging tracks in a mesotidal environment. In the second patient, an endoloop was attached to the base of the previously placed hemoclips because of rebleeding. It was found that patients in the community who are unprotected by medication are vulnerable either to acute stress in the form of life events or to chronic stress in the form of living with a high Expressed Emotion relative. The proportion of participants with each ROM limitation compared with all participants with the same SMA type, age distribution of the participants with each ROM limitation, mean range loss of each motion limitation, and the contracture index (risk index of joint contracture). Three Kirschner wires were then inserted to maintain the closed reduction, followed by immobilization in a spica cast.

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The results describe that opinion leader activity is effective in an informal context in which the practicing physician initiates the exchange. To evaluate tear levels of neuromediators in patients with dry eye disease and to identify statistical correlations with the clinical findings. Reducing stability of support structure for a target does not alter reach kinematics among younger adults. Effect of iontophoretic etorphine and electroacupuncture on nociceptive response from nucleus lateralis anterialis of thalamus in rabbits. Also, our tetO-Cre transgene can be combined with any of the increasing number of tetracycline transactivator transgenic strains to direct specifically inducible genomic recombination to several areas of the brain. Caffeine suppresses metastasis in a transgenic mouse model: a prototype molecule for prophylaxis of metastasis. The MR angiography (MRA) and contrast-enhanced (CE) T1-weighted MRC images then were obtained after injecting a single dose of gadobenate dimeglumine. Pharmacokinetic data in humans have been achieved with ultra-low levels of radiolabel. The calculated energy difference between enantiomers, about 1.5 x 10(-19) hartree, is roughly eight orders of magnitude smaller than the upper bound suggested by available spectroscopic investigations on the frequency of a spectroscopic transition.

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Inductive effects of 1,1,1-trichloro-2,2-bis(p-chlorophenyl)ethane(DDT), phenobarbital, and benzpyrene on microsomal cytochrome B450, ethyl isocyanide spectra, and metabolism in vivo of zoxazolamine and hexobarbital in the mouse. Whole blood prevents ICG toxicity in RPE cell culture and prevents staining of RPE in surgery of MH when the ILM is stained with ICG. These findings have implications for secondary prevention in Ireland. Our study obtained results similar to those published by other groups regarding the resection of benign lesions in lung cancer surgery. Among the proteins that were more abundant under oxygen exposure, several thiol-specific peroxidases (thiol-peroxidase, BCP-like protein, and putative glutaredoxin) were identified.

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The aim was to determine the proportion of patients with cancers that masqueraded as cysts and to establish whether short-term follow-up was necessary. It is suggested that the inhibition by AVP of a pressor response produced by MRF stimulation involves the dorsal hippocampus. The combination of BWS with fast speed produces the greatest increments in walking speed in all subjects. Our results suggest that the IL-4 and HGF pathways converge at multiple levels, and that IL-4-dependent Jak3 and STAT6 activities modulate signaling events independent of PI3K to enhance HGF-dependent mitogenesis in myeloid cells, and possibly other common cellular targets. Water deficit and carbon depletion impacted either source size, source activity, or sink strength with contrasted effects on fruit growth. Hyperandrogenic conditions in women are associated with increased rates of miscarriage. All eight ZmEXPs were found to be significantly regulated by ABA and GA3 in endosperm, suggesting important roles for these hormones in the regulation of ZmEXPs during endosperm development. We evaluated the expression of GRIM-19, a novel gene essential for normal development, in various grades of gliomas and several human glioma cell lines.

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The evidence is substantial that primary affective disorders are genetically inherited. These results suggest that EBF activity is important for both stabilizing commitment and driving aspects of differentiation in Xenopus muscle cells. Metastatic PEComa of the lung and ileum should differentiate from primary carcinoma, metastatic carcinoma, malignant melanoma, and gastrointestinal stromal tumor. However, as the outstanding British obstetrician between 1840 and 1870, he also pioneered many other advances in obstetrics. Effects of hypothermia on the liver in a swine model of cardiopulmonary resuscitation. The aim of this study was to assess the rate of discrepancy between histologic diagnoses from biopsy specimens and ER specimens.

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For this reason, it is essential to become familiar with normal structures before describing the pathologic condition. A 33-year-old Japanese woman was admitted at 40 weeks gestation for evaluation of preeclampsia. A variety of management approaches have been developed in pursuit of more rational and cost-effective use of health resources. These challenges include poor proton permeability, substrate loss, oxygen back diffusion, pH gradient, internal resistance, biofouling, etc. Sensitivity of joint kinematics and kinetics to different pose estimation algorithms and joint constraints in the elderly. We show here, for the first time, that tagging with the parasite rhoptry protein ring surface protein 2 (RSP2) is not restricted to the surfaces of normal erythrocytes, as previously reported, but that it extends to erythroid precursor cells in the bone marrow of anemic malaria patients. The molecular events involved in lymphatic development are poorly understood. Pain is an unpleasant and subjective sensation that results from a harmful sensorial stimulation, which alerts the body about current or potential damage to its tissues and organs. Data recorded on the Maternity Record Form designed by the International Fertility Research Program and the International Federation of Gynecology and Obstetrics were used for analysis what is anafranil tablet .

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New prevacid odt dose considerations about the duration of the fortification and the use of probiotics have led to an update of these CPG. ABO test results were concordant for 7115 of 7124 patient samples and discordant for nine. In this paper, we report the identification and the localization of specific isobaric minor phospholipids in human breast cancer xenografts by FTICR MALDI imaging supported by histochemistry. System of defense are rapidly overwhelmed and tumor cells hijack host cells to promote their dissemination that likely occurs at earlier stages than initially anticipated. Biochemical aspects of a new hormone: rat atrial natriuretic factor (rANF). There were no significant differences between the annual NO3 load estimates using non-intensive sampling methods and the actual NO3 loads. The German Federal Joint Committee (the highest decision-making body of physicians and health insurance funds in Germany) has established minimum caseload requirements with the goal of improving patient care. In a 24-year-old patient the diagnosis panarteritis nodosa intra vitam was made. Soluble products of Escherichia coli induce mitochondrial dysfunction-related sperm membrane lipid peroxidation which is prevented by lactobacilli.

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Effects of a P-glycoprotein inhibitor on brain and plasma concentrations of anti-human immunodeficiency virus drugs administered in combination in rats. Electrocardiographic changes announcing the rapid development of apical hypertrophic cardiomyopathy in an adult male. Characteristics peculiar to the culture of the deaf population indicated the necessity of adapting the application methodology of focal groups composed of deaf people. The antioxidant potency of the extract was different between muscle and endothelial cells suggesting that the antioxidant activity depends on cell type. Plain films for 41 patients aged 46 to 87 years (mean 69) were assessed by two musculoskeletal specialist radiologists for seven features (retained or new metalwork, retained cement or restrictor, new fracture, local antimicrobial delivery system and drain) we hypothesised may predict for failure. Disease stage is the most important prognostic factor in lung cancer, and optimal staging is important to determine the best therapeutic option. All but 11 of the 120 specimens failed through the solder joint, which confirms that the solder joint is usually the weakest part of a fixed partial denture. During a 12-month period, all adult patients who underwent elective general surgical procedures under general anaesthesia during weekdays, were transferred to the recovery ward after extubation, and those who required NIV were included in this prospective observational study. This study investigates the effect of intraoperative narrow band imaging (NBI) examination on the incidence of positive superficial surgical margins in early glottic cancer treated by TLM. The IOP was measured at intervals of 4-6 weeks, and the visual fields were examined at least twice a year for 3 years.

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This approach gives side effects of prilosec medication continuity in surfaces as well as better capture of isosurface features of the medical dataset. Mucins are high molecular-weight glycoproteins having oligosaccharides attached to serine or threonine residues of the mucin core protein backbone by O-glycosidic linkages. Obesity is associated with multiple adverse reproductive outcomes such as infertility, ovulation dysfunction, miscarriage, preeclampsia, gestational diabetes mellitus, preterm delivery, operative delivery, and fetal growth disorders. Imaging cocaine-induced changes in the mesocorticolimbic dopaminergic system of conscious rats. Although mortality rates were significantly higher in the rural area, rural setting was not a risk factor for infant mortality. Analysis of MEFV exon methylation and expression patterns in familial Mediterranean fever. Pancreatic hormone profiles and metabolism posthepatectomy in the dog.

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