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Actos (Pioglitazone)
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Actos

Actos works by making cells more sensitive to insulin, which is used to regulate the level of glucose in the body. Improving insulin sensitivity (or reducing insulin resistance) makes it easier for sugar (glucose) in the blood to get into the cells.

Other names for this medication:
Amaryl, Asoformin, Diamet, Diazero, Dimbest, Euglim, Exerme, Gamaryl, Glimiprime, Glimitab, Glimkap, Glitafor, Glito, Gluconorm, Glyciphage, Glycirest, Matce, Mefomin, Metme, Metride, Pglit, Pianorm, Pioglar, Pioglitazone, Piokare, Piomed, Piomeri, Piozone, Piozulin, Prichek, Tribet, Trigem, Triglaz, Trigulin, Triopil, Vogipax, Zipio, Zogli

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Also known as: Pioglitazone

Description

Actos is a medication that’s used to treat type 2 diabetes. This is a condition in which where your body has a high level of glucose (sugar) in your blood. Your pancreas normally makes a hormone called insulin, which takes glucose out of your blood and helps you use the sugar as a source of energy. With type 2 diabetes, your pancreas may not be making enough insulin to remove the sugar from your blood.

And if you have type 2 diabetes, your cells may also become insulin resistant. This means that your body makes insulin but isn’t responding to it by removing the sugar from your blood. So people with type 2 diabetes have high blood sugar levels.

What Actos does

Actos works by making your cells more sensitive to insulin. The goal is for your cells to take the glucose in your blood and use it more effectively as an energy source. Because you’re using your glucose more effectively, your blood glucose levels will decrease.

This lowers your risk of serious complications of type 2 diabetes, including heart disease, nerve damage such as neuropathy, and kidney failure.

How long does it take to work?

After you start using Actos, it may take 7 days or longer before you notice any changes in your blood glucose level. It’s important to keep taking Actos every day so that it can have the best chance to work in your body.

Dosage

Take Actos by mouth with a full glass of water with or without food. The initial dose of Actos is 15 mg once a day. In case of inadequate glycemic control, the dose can be increased up to 45 mg once daily. If hypoglycemia occurs in a patient co-administering Actos and insulin, the dose of insulin should be decreased by 10% to 25%. Further adjustments to the insulin dose should be individualized based on glycemic response. Take the drug at the same time each day. If you want to achieve the most effective results, do not stop taking Actos suddenly.

Overdose

If an overdose occurs and you are not feeling well, you should seek emergency medical attention or contact your health care provider immediately. You can experience the following symptoms of Actos overdose: signs of low blood sugar, such as extreme weakness, blurred vision, sweating, trouble speaking, tremors, stomach pain, confusion, and seizure (convulsions).

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) and away from excess moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Actos are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Avoid drinking alcohol. It lowers blood sugar and may interfere with your diabetes treatment.

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