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Adapalene

Adapalene is a topical retinoid with FDA approval for the treatment of acne vulgaris. Clinicians use retinoids are used to treat a wide variety of skin disorders. Adapalene also has multiple off-label therapeutic applications.

Other names for this medication:
Aclene, Acneril, Acneris, Acniriv, Acnovate, Adaferin, Adapalene, Adapen, Adaple, Adaret, Adgraze, Adiff, Adina, Aditop, Adlene, Alangel, Apalene, Apgel, Clinred, Daple, Deriva, Difra, Edplin, Faceclin, Labopene, Medapine, Rozac, Soflene, Vandep, Zolvee

Similar Products:
Biaxin, Reminyl, Nimotop, Compazine, Thorazine, Luvox, Detrol

Description

Adapalene is a third-generation topical retinoid primarily used in the treatment of acne. Adapalene is a gel used for the treatment of acne (blackheads, whiteheads and pimples) of the face, chest or back. Adapalene gel is a clear gel that powers deep inside your pores to control the buildup that leads to acne. It helps prevent the formation of new acne lesions, and can also help get rid of lesions already present. Adapalene works under the skin surface to unclog pores and clear up pimples. Adapalene is also known as Adapalene, Adapen, Adaferin. Generic name of Adapalene is Adapalene.

Dosage

Follow the directions for using this medicine provided by your doctor. Use Adapalene exactly as directed. Adapalene is best applied after washing and drying your skin. Apply a thin layer of gel to the affected areas once daily at bedtime. Avoid the eyes, lips and nose. Do not allow this preparation to come into contact with the mucous membranes (e.g. mouth, vagina, inside of nose etc.). Try not to touch the treated areas overnight. Do not use any harsh soaps or exfoliants while you are being treated with Adapalene. Adapalene should not be used on broken, sunburnt or infected skin. You may notice a slight change of colour of the skin you are applying this preparation to. This is only temporary and should return to normal soon after finishing treatment with Adapalene. Continue using Adapalene until no new acne spots appear. You may need to use it for several months. You should notice some clinical improvement after 4-8 weeks and more improvement after further use. There may be a worsening of acne during the first few weeks of therapy because Adapalene promotes the growth of pimples that have begun to form but are not yet visible. Therefore, treatment should not be stopped if acne appears to be worsening. Use a sunscreen cream and wear protective clothing if exposure to strong or prolonged sunlight cannot be avoided. Weather extremes such as wind or cold may also be irritating.

Overdose

If you overdose Adapalene and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Store at a room temperature between 20 and 25 degrees C (68 and 77 degrees F) away from moisture, light and heat. Throw away the after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Adapalene are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Avoid exposure to sunlight or tanning beds. Adapalene can make you sunburn more easily. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors.

Avoid using other skin medications that contain sulfur, resorcinol, or salicylic acid (common in topical acne medications or skin cleansers).

Avoid using skin products that can cause irritation, such as harsh soaps, shampoos, or skin cleansers, hair coloring or permanent chemicals, hair removers or waxes, or skin products with alcohol, spices, astringents, or lime.

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Diabetic cardiovascular autonomic neuropathy: clinical implications. In vitro decrease of glomerular heparan sulfate by lymphocytes from idiopathic nephrotic syndrome patients. The concentrations of high-mobility-group proteins HMG1, HMG2, and HMG17 in the nucleus and cytoplasm were then estimated from the staining intensities of the electrophoretic bands. Recent advances have demonstrated that many monogenic IGEs are ion channelopathies. We also performed an ultrastructural radioautographic study of RNA synthesis during oogenesis in order to examine the part played by the rachis in the transport of nutritive substances. To visualise this current, ink or fluorescent microspheres were released by a microcapillary near the posterior opening of the brood chamber.

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