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Adapalene is a topical retinoid with FDA approval for the treatment of acne vulgaris. Clinicians use retinoids are used to treat a wide variety of skin disorders. Adapalene also has multiple off-label therapeutic applications.

Other names for this medication:
Aclene, Acneril, Acneris, Acniriv, Acnovate, Adaferin, Adapalene, Adapen, Adaple, Adaret, Adgraze, Adiff, Adina, Aditop, Adlene, Alangel, Apalene, Apgel, Clinred, Daple, Deriva, Difra, Edplin, Faceclin, Labopene, Medapine, Rozac, Soflene, Vandep, Zolvee

Similar Products:
Biaxin, Reminyl, Nimotop, Compazine, Thorazine, Luvox, Detrol


Adapalene is a third-generation topical retinoid primarily used in the treatment of acne. Adapalene is a gel used for the treatment of acne (blackheads, whiteheads and pimples) of the face, chest or back. Adapalene gel is a clear gel that powers deep inside your pores to control the buildup that leads to acne. It helps prevent the formation of new acne lesions, and can also help get rid of lesions already present. Adapalene works under the skin surface to unclog pores and clear up pimples. Adapalene is also known as Adapalene, Adapen, Adaferin. Generic name of Adapalene is Adapalene.


Follow the directions for using this medicine provided by your doctor. Use Adapalene exactly as directed. Adapalene is best applied after washing and drying your skin. Apply a thin layer of gel to the affected areas once daily at bedtime. Avoid the eyes, lips and nose. Do not allow this preparation to come into contact with the mucous membranes (e.g. mouth, vagina, inside of nose etc.). Try not to touch the treated areas overnight. Do not use any harsh soaps or exfoliants while you are being treated with Adapalene. Adapalene should not be used on broken, sunburnt or infected skin. You may notice a slight change of colour of the skin you are applying this preparation to. This is only temporary and should return to normal soon after finishing treatment with Adapalene. Continue using Adapalene until no new acne spots appear. You may need to use it for several months. You should notice some clinical improvement after 4-8 weeks and more improvement after further use. There may be a worsening of acne during the first few weeks of therapy because Adapalene promotes the growth of pimples that have begun to form but are not yet visible. Therefore, treatment should not be stopped if acne appears to be worsening. Use a sunscreen cream and wear protective clothing if exposure to strong or prolonged sunlight cannot be avoided. Weather extremes such as wind or cold may also be irritating.


If you overdose Adapalene and you don't feel good you should visit your doctor or health care provider immediately.


Store at a room temperature between 20 and 25 degrees C (68 and 77 degrees F) away from moisture, light and heat. Throw away the after the expiration date. Keep out of the reach of children.

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The most common side effects associated with Adapalene are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Avoid exposure to sunlight or tanning beds. Adapalene can make you sunburn more easily. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors.

Avoid using other skin medications that contain sulfur, resorcinol, or salicylic acid (common in topical acne medications or skin cleansers).

Avoid using skin products that can cause irritation, such as harsh soaps, shampoos, or skin cleansers, hair coloring or permanent chemicals, hair removers or waxes, or skin products with alcohol, spices, astringents, or lime.

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Distribution of sodium transporters and aquaporin-1 in the human choroid plexus. But aplastic anemia hemodialysis even guzzling excessive amounts of carbonated beverage have being reported. This study compared the clinical and bacteriologic efficacy and tolerability of oral clindamycin with those of oral amoxicillin/clavulanic acid in the outpatient treatment of acute recurrent GABHS pharyngotonsillitis. These preliminary results from the wetland show marked seasonal changes in dissolved concentration for all elements except Zn and Cu. An extract from the marine alga Ulva lactuca was highly osmoprotective in salt-stressed cultures of Sinorhizobium meliloti 102F34. The offensive cod liver oil-like odor which Synura imparts to the raw water was traceable to trans,cis-deca-2,4-dienal and minor amounts of trans,cis-hepta-2,4-dienal. Functional and immunological characterization of ATPase inhibitor proteins from heart, liver and yeast mitochondria. CCL27 secretion and mRNA levels were analyzed by means of ELISA and RT-PCR, respectively. The PbMDJ1 gene belongs to a conserved MDJ1/LON locus in thermodimorphic pathogenic fungi and encodes a heat shock protein that localizes to both the mitochondria and cell wall of Paracoccidioides brasiliensis.

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