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Alant (Alendronate)

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Alant is used to prevent and treat certain types of bone loss (osteoporosis) in adults. Osteoporosis causes bones to become thinner and break more easily. This medication works by slowing bone loss. Alant belongs to a class of drugs called bisphosphonates.

Other names for this medication:
Alant, Alendix, Alendronate, Alenost, Bifosa, Denfos, Osteofos, Ostogee, Poronil, Ralenost, Restofos, Zophost

Similar Products:
Nimotop, Mellaril, Glucophage, Geodon, Benemid, Casodex, Seroquel, Paxil, Colcrys, Clozaril

Also known as: Alendronate


{name} Plus D contains a combination of alendronate and cholecalciferol. Alendronate is a bisphosphonate medicine that alters bone formation and breakdown in the body. This can slow bone loss and may help prevent bone fractures.

Cholecalciferol is a form of vitamin D, and is important for the absorption of calcium from the stomach and for the functioning of calcium in the body.

{name} Plus D is used to treat and prevent osteoporosis.


Take Alant Plus D exactly as it was prescribed for you. Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.

Alant Plus D tablets are taken once each week. Choose the day of the week that best fits your schedule. Every week, take one Alant Plus D tablet on your chosen day.

Take the Alant Plus D tablet first thing in the morning, at least 30 minutes before you eat or drink anything or take any other medicine.

Take the tablet with a full glass (6 to 8 ounces) of water. Use only plain water (not mineral water) when taking this medicine.

Do not crush, chew, or suck the tablet. Swallow the pill whole.

After taking an Alant Plus D tablet, carefully follow these instructions:

Do not lie down or recline for at least 30 minutes after taking Alant Plus D. Do not eat or drink anything other than plain water. Do not take any other medicines including vitamins, calcium, or antacids for at least 30 minutes after taking Alant Plus D. It may be best to take your other medicines at a different time of the day. Talk with your doctor about the best dosing schedule for your other medicines.

To be sure this medication is helping your condition, your bone mineral density will need to be tested on a regular basis. You may not need to take Alant Plus D for longer than 3 to 5 years if you take it for osteoporosis.

If you need to have any dental work (especially surgery), tell the dentist ahead of time that you are using Alant Plus D. You may need to stop using the medicine for a short time.

Alant Plus D is only part of a complete program of treatment that may also include diet changes, exercise, and taking calcium and vitamin supplements. Follow your diet, medication, and exercise routines very closely.

Store at room temperature away from moisture and heat.

Detailed Alant Plus D dosage information


If you overdose Generic Alant and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Generic Alant overdosage: heartburn, stomach pain, diarrhea, numbness, tingling, tight muscles in your face, irritability, unusual thoughts or behavior, nausea, muscle cramps, convulsions.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Alant are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not take any other medicines including vitamins, calcium, or antacids for at least 30 minutes after taking Alant Plus D.

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No palliative therapeutic option has clearly demonstrated any benefit on overall survival. Childhood neglect and abuse, as measured by retrospective interview, is highly predictive of psychiatric disorder in adult life and has an important role in aetiological models. Moreover, impairment of NFATC2-calcineurin interaction with 11R-VIVIT further reduced the transcription of the NFATC2 gene. We show the extent to which botulinum toxin treatment has been taken into use in our department and discuss advantages and disadvantages of giving botulinum toxin injections at local hospitals. To systematically review the published literature on data monitoring committees (DMCs) for randomized controlled trials (RCT) and summarize information and opinions on best practice. Measuring radioactive methane with the liquid scintillation counter. Its activity in seminal plasma may be derived from various organs, although the major sources are probably the apical activity in the epididymis, ampulla and seminal vesicle. An extrinsic substance (ES-6000) was isolated from the periplasmic space of Rhizobium trifolii (strain 4S) cells by osmotic shock, using a high-density sucrose solution. Retrospective analysis of 311 patients treated with modified radical (86) or radical (225) neck dissection. Infant psychiatry is a discipline concerned with diagnostic assessment, treatment, and prevention of mental health problems in infancy and early childhood.

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The genetic basis of vertebrate morphological evolution has traditionally been very difficult to examine in naturally occurring populations. In this review, our current knowledge of the molecular functions of Ikaros will be discussed. Factor H of the human complement system exhibits an unusual circular dichroism spectrum. Patients presenting with suppurative keratitis in India underwent detailed clinical examination followed by microbiological investigation of corneal scrapes. The different histoanatomical patterns of the TA, as well as the mode of attachment of the ischio-/bulbo-cavernosus muscles (ICM, BCM) to the TA, were studied, aiming at elucidating their role in the mechanism of erection. In a 4-day treatment regimen, teicoplanin was as effective as either nafcillin or vancomycin in eliminating organisms from aortic valve vegetations in the respective infection.

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These findings might provide the mechanistic rationale for the current use of proteases in wound healing and tissue regeneration since these processes depend on IL-6 induction. Viremias were of similar magnitudes and durations in normal and nude mice. While lipid mixing occurred at pH 7, the kinetics of insertion of the fusion peptide was increased at pH 5, consistent with the location of DHBV in the late-endosome compartment and previous studies of the nonessential role of low pH for infectivity. DNA analysis revealed a homozygous R553X mutation, and both his parents were subsequently proven to be R553X carriers. Changes in airway resistance and alveolar trapping with positive-negative ventilation. An 11-year-old boy presented with right medial canthal swelling. A urological x-ray study table with a 36-cm x-ray image intensifier. Our findings suggest that preserving relationship quality through daily experiences is best achieved by equipping couples to recognize the benefits of uplifts to the relationship, especially uplifts that are nonsocial, in tandem with managing hassles. Functional status and medical complications during the first year post lung transplantation (LTX).

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The effects of solvation were considered using the Langevin dipoles and solvent reaction field methods. The prevalence of client injuries in activity sectors not presently covered by government regulation, suggests policy makers should look again at extending codes of practice to a wider range of adventure tourism activities. Optical investigations to avoid the disturbing influences of furrows and wrinkles quantifying penetration of drugs and cosmetics into the skin by tape stripping. Sonography correctly excluded the presence of hydronephrosis in 173 of 192 nonobstructed kidneys. Imaging evaluation of acute chest pain: systematic review of evidence base and cost-effectiveness.

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23 SNP sites were amplified by PCR method, sequenced and analyzed by clustering analysis. Effects of p-chlorophenylalanine on ventilatory control in goats. We theoretically derive the representation of generalized coherent states to reconstruct the experimental polarization-resolved patterns. Pathogenesis and evolution of virulence in enteropathogenic and enterohemorrhagic Escherichia coli. Biphenyl metabolism in isolated rat hepatocytes: effect of induction and nature of the conjugates. For this purpose, a synthetic CrtI gene with a codon usage matching that of rice storage proteins was generated. Characteristics of woodland rhizobial populations from surface- and deep-soil environments of the sonoran desert. Other variables considered included age, gender, coma duration, and fracture distribution. Scaling of maximal oxygen uptake by lower leg muscle volume in boys and men.

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Despite recent advances in the treatment of vascular injuries, the prognosis of injuries to the popliteal vessels is still poor with an incidence of 10-40 p. The aim of this study was to morphologically characterize intestinal connective tissue in fetal and postnatal development and intestinal pseudo-obstruction. An external pancreatic fistula (EPF) generally results from an iatrogenic manipulation of a pancreatic fluid collection (PFC), such as walled-off pancreatic necrosis (WOPN). When crude extracts are separated using size-exclusion chromatography, several fractions retain multiple cardiac activities. Lesions were treated with the study dressing for a maximum of four weeks.

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This article presents MST estimates associated with the newer Hemoccult SENSA test and describes differences in MST by the location of cancer in the colorectum and age at the time of screening. Brown fat is a thermogenic organ that allows newborns and small mammals to maintain a stable body temperature when exposed to cold. Independent evolution of orthologs after polyploidization and mechanisms of local rearrangements at paralogous loci. The absence of Trypanosoma congolense from the lymph of an infected sheep. In the ETX group and the ETX/H1-ANT group both microvascular permeability and mast cell activity increased significantly, starting at 60 minutes. Production of carcinogenic acetaldehyde by Candida albicans from patients with potentially malignant oral mucosal disorders. Dissimilatory reduction of NO(2) to N(2)O and NH(4) by a soil Citrobacter sp. The three-dimensional (3-D) shape of microcalcification clusters is an important indicator in early breast cancer detection.

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Diagnostic tools that seemed promising have been unmasked as unreliable, and new treatment options such as angioplasty have failed to demonstrate their superiority. Key findings include the strong temperature dependence of the critical length scale for hydrophobic dewetting and the evaluation of fundamental solute-solvent interaction contributions to rare-gas hydration chemical potentials. Review of the literature, has revealed eight such cases with very few survivals. DEFRA outlines its plans for implementing the European avian influenza directive. Diffuse lesions in the CNS revealed by MR imaging in a case of Whipple disease.

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Lack of ability of trypsin-treated mitochondrial F1-ATPase to bind the oligomycin-sensitivity conferring protein (OSCP). Influence of repeated chlorhexidine varnish applications on mutans streptococci counts and caries increment in patients treated with fixed orthodontic appliances. To compare the quality of volumetric modulated arc therapy (VMAT) or intensity-modulated radiation therapy (IMRT) plans generated by an automated inverse planning system with that of dosimetrist-generated IMRT treatment plans for patients with stage III lung cancer. Early reduction of commensal flora (particularly Lactobacillus species) and, at the same time, overgrowth of Enterobacteriaceae, especially Escherichia coli, have recently been described during acute pancreatitis. The effects of scopolamine and diazepam on attenuation of schedule-induced polydipsia (SIP) produced by a dopamine D1 antagonist, SCH 23390, a dopamine D2 antagonist, raclopride, and a mixed D1/D2 antagonist, cis(Z)-flupentixol, were examined in a chronic dose regime, followed by 7 days of withdrawal. Prevention of severe hard-of-hearing or deafness in young children. The high morbidity associated with SCI could be reduced through public enlightment on road safety measures including use of seat belts, prohibition of carrying goods and passengers together in trucks. These groups correlate with the geographical distribution of strain isolation and indicate that the L and S segments of CCHF viruses have evolved together. The lower LUB values, which imply a better utilization of the bark bed, were obtained at the higher flow rate. The Day 2 VX pigeons in general had a lower Tc than that in SVX and as Ta continued to drop below 28 degrees C, Tc in VX pigeons dropped more rapidly than in SVX, showing the maximal difference in Tc between the two at Ta 2 degrees C.(ABSTRACT TRUNCATED AT 250 WORDS).

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The advantages of transverse or interneural incisions are obvious. This circulatory dysfunction is the consequence of arterial vasodilation in the splanchnic circulation. Evaluation of some kinds of gingival massage by means of the measurement of the local capillary blood flow. Monolithic wavelength converter for ultraviolet light by use of a Gd(x)Y(1-x)Ca4O(BO3)3 crystal. Agonist-specific regulation of monocyte chemoattractant protein-1 expression by cyclooxygenase metabolites in hepatic stellate cells. Hemicellulose composition of dietary fiber of milled rice and rice bran. Laboratory column tests confirmed that the transport characteristics of Clostridium bifermentans DPH-1 in activating tetrachloroethylene dechlorination could be described by mobile-immobile two-region model.

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The mRNAs localized to different domains: Nkx3-1 was present along about half the prostatic bud length while Edar and Wnt10b were restricted to distal bud tips. Morphology and topography of the carotid body and carotid sinus in sheep (Ovis ammon f. Expression of B7-H1 in inflammatory renal tubular epithelial cells. The risk can be reduced if patients and relatives are taught how to remove the dentures prior to or during seizures. Recipient B cell persistence may contribute to the frequency and/or severity of cGVHD after RICT. Nasal mucociliary transport time (MCTt) was significantly shorter for the non-swimmers than for the swimmers. This spatio-temporal shift in insulin sensitivity throughout pregnancy allows maternal and foetal insulin to regulate different processes within the placenta at different gestational stages, facilitated by compartmentalisation of the insulin response. Fresh frozen plasma transfusion in critically ill medical patients with coagulopathy.

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We have analysed a suite of 12 state-of-the-art climate models and show that ocean warming and sea-level rise in the twentieth century were substantially reduced by the colossal eruption in 1883 of the volcano Krakatoa in the Sunda strait, Indonesia. Effect of flurbiprofen and acetylsalicylic acid on the ultrastructure of blood platelets. Given systemically, amitriptyline (30 arcoxia 90 mg para q sirve or 100 micrograms intraperitoneally) was ineffective. Despite being a wound treatment method with a broad spectrum of indications, vacuum-assisted wound closure (VAWC) can be a painful treatment modality which may even result with patient unwillingness for the continuation of treatment. Structural and hormonal changes in the brain and ovary play a critical role in determining the onset of reproductive senescence. Analysis of the reduced enzyme alkylated with 4-vinylpyridine showed that the gamma subunit contains four cysteinyl residues. In this pilot study, urinary CTx-II concentration was not a useful biomarker of osteoarthritis progression.

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Both models are compared with respect to the correctness of the model assumptions, goodness of fit, and predictive behavior. The enantiomeric composition of L- and D-enantiomeric mixtures could be quantitatively determined by the fabricated sensor. Plasma haemoglobin and anti-penicillin antibodies could be removed by an early exsanguino-transfusion. Action of Hygrophila auriculata against streptozotocin-induced oxidative stress. In our cohort of patients, the polymorphism in codon 511 of the ARNT gene is not associated with RM. The new model was developed from the same database as RMS, side effects of tinidazole 500 mg but it used Chi-squared Automatic Interaction Detection (CHAID).

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Altered expression and mutation of beta-catenin gene in gastric carcinomas and cell lines. Bispectral index scores monitoring may prove useful for earlier ED treatment and decision making regarding sedative overdose patients. Furthermore, in a 3-day-old chick, pro-opiomelanocortin mRNA was detectable by in situ hybridization only in the photoreceptor layer and not in the RPE cells. The variation of the diffusion potential with external K was fitted by a PNa:PK ratio five times lower than in normoxia. To assess the use of indwelling tracheoesophageal speaking valves in Chinese patients undergoing laryngectomy, to identify the clinicopathologic factors for favorable outcome, and to evaluate the factors that determine prosthesis lifetime. Quantitative analysis of glutamate transporter mRNA expression in prefrontal and primary visual cortex in normal and schizophrenic brain. The use of the nominal group technique as an evaluative tool in the teaching and summative assessment of the inter-personal skills of student mental health nurses. The risperdal medication names disruption of cell contacts temporarily delayed onset of gene expression but by 48 h both Msx2 and Dlx5 were expressed.

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Although physicochemical and immunological properties of AFP have been well-studied, its biological role in embryo- and carcinogenesis and in adult organisms as well as mechanisms underlying its functioning remain unclear. Among the young, the females not having a college education and married men who are smokers seem to be target populations for promoting physical activity. In melanocyte dysfunction disease, it is observed that the expressions of MITF, tyrosinase (TYR), tyrosinase related protein 1 (TYRP1) and tyrosinase related protein 2 (TYRP2)/dopachrome tautomerase (DCT) are changed, the consequence of which remains unclear. All these differences make melanotrope subtypes an excellent model to analyze the expression and regulation of genes involved in the control and maintenance of the secretory state of endocrine cells. Nicorandil (50 micrograms kg-1, i.v.) increased the pH that had been reduced by partial occlusion and this effect lasted at least 60 min. The technology consists of a combination of solvent systems and permeation enhancers enabling systemic drug delivery, and is covered by many patents.

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Cardiac memory (CM) is identified as an altered T wave on electrocardiogram and vectorcardiogram that is seen when sinus rhythm resumes after a period of abnormal myocardial activation. Blood levels of maternal glycosylated hemoglobin (HbA1) in the 3d day of the puerperium and neonatal anthropometric parameters. It also encourages prospective decision making and provides advance care directives for patients making and provides advance care directives for patients and their decision-making surrogates to do so. Plasma and brain acetylcholinesterase activity was significantly decreased. The mean age of the first symptoms of TS was significantly lower than the onset of CMVT. Anti-HMGB1 mAb may provide a novel and effective therapy for TBI by protecting against BBB disruption and reducing the inflammatory responses induced by HMGB1. Considerations when conducting study of semen indices in workplaces. The neurite-stimulating activity of the purified protein manifests itself at a protein concentration of about 10(-9) M. These data suggest that the allergic diathesis is a model for the study of cyclic, nondrug induction of platelet dysfunction. In addition the present study demonstrated that the experimental iron deficiency anemia induces cardiac hypertrophy, as revealed by increased heart weight associated with increased size of cardiac muscle cells, as well as decreased myocardium catecholamine levels.

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This article presents a hypothesis that the transition from quadrupedal to habitual upright bipedal locomotion was caused by qualitative changes in the nervous system that allowed controlling the more demanding type of locomotion. Our results of increased IL-6, IL-6xsIL-6R, and sIL-2R in patients with SAD suggest an activation of the immune-inflammatory system in winter depression, which is not altered by 2 weeks of successful light therapy. After simultaneous application of (3)H-sucrose and (14)C-labelled phloem-mobile amino acids, phytohormones, and xenobiotica to the host, corresponding percentages of the translocated compounds are found in the parasite. FDG-PET scanning is a simple, expensive, but powerful means to restage thyroid cancer patients who develop subsequent metastases, assigning them to groups that are either at low (FDG negative) or high (FDG positive) risk of cancer-associated mortality. The degree of morphologic degeneration and of lactate dehydrogenase (LDH) efflux into the extracellular medium (as an index of cell viability) were determined in endothelial cell culture exposed for 10, 30, or 60 minutes to ioxaglate or iohexol (ionic and nonionic contrast media, respectively) at iodine concentrations of 100 or 150 mg/mL. This review, however, focuses on the impact of MDCT on the routine practice of thoracic imaging, rather than on newer specific MDCT applications. The difference between white cell pellet and serum was not significant. Microscopic lesions in the brain were subtle in 2 zofran odt 4 mg how often can i take animals and absent in the third case. Cortical activation during cholinesterase-inhibitor treatment in Alzheimer disease: preliminary findings from a pharmaco-fMRI study. macrostroma, and its phylogenetic relationships to other species with large stromata.

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We propose that HIV-Tg26 mice are a clinically relevant model system to study the role of FGF-BP in the pathogenesis of HIV-associated renal diseases. His personal style of counselling and his sensitivity and receptivity in dealing with the problems of the individual patient will determine the weight of his advice. The data suggest that children may have an impaired HPA axis after early trauma. (1) To study if young, Swedish men have poorer or better hearing according to screening at conscription in 1988 compared to 1969-1977. A significant positive correlation was found between participation in sports and involvement in aggressive behaviour. Investigation of coronary artery calcification and stenosis by coronary angiography (CAG) in haemodialysis patients. The Evra (ethinyl estradiol/norelgestromin) contraceptive patch: estrogen exposure concerns.

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The physical findings were a disproportionate motor paralysis, non anatomical sensory loss, the presence of downgoing plantar responses, normal tone and reflexes. Results of ecologic investigations of the population of Ixodes ricinus in 1963. 4-Methylpyrazole may be an alternative to ethanol therapy for ethylene glycol intoxication in man. Where diseases and networks collide: lessons to be learnt from a study of the 2001 foot-and-mouth disease epidemic. Water intoxication associated with non-steroidal anti-inflammatory drug therapy.

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Then, the position and orientation of the three orthogonal semiaxes of the ellipsoid, which define the intrinsic Cartesian system of coordinates for normal corneas, can be identified by passing to the canonical form, by standard linear algebra. Distension of part of the human isthmus is likely to disturb normal gamete transport through the isthmus. Effects of acute changes in load and inotropic state on the exponential rate of fiber shortening and other indices of myocardial contractility in the anesthetized intact dog. To test this prediction we have analysed the product stereochemistry by circular dichroism spectroscopy and confirmed the production of (S)-2-methylsuccinate. A new model is proposed and verified through experimental results of simulation samples made of glycerol and methyl-red-doped poly(methyl methacrylate).

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Light and electron microscopy localization of the 11beta-hydroxysteroid dehydrogenase type I enzyme in the rat. However, virtually nothing is known about the membrane block to polyspermy in mammalian eggs, despite data dating back 50-90 years that provide evidence for its existence. Peripheral motor neurone dysfunction: unique manifestation of syphilis. Evolution of the venom system is thought to underlie the impressive radiation of the advanced snakes (2,500 of 3,000 snake species). Therefore, we suggest that LpTFL1 is a repressor of flowering and a controller of axillary meristem identity in ryegrass. Adolescent binge/purge and weight loss behaviors: associations with developmental assets. Relationship between tracheostomy timing and duration of mechanical ventilation in critically ill patients. In this work we report the design and use of vectors containing some of these spectral variants of GFP for use in the Gram positive bacterium Bacillus subtilis. Hippocampal neurodegeneration, spontaneous seizures, and mossy fiber sprouting in the F344 rat model of temporal lobe epilepsy.

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The algorithm is used to determine an effective propagation constant in a monodisperse medium from the observation of the energy decay in the medium. Percutaneous closure of an aorta to left atrium fistula with an Amplatzer duct occluder. Preparation of immobilized cholinesterase for use in analytical chemistry. Outcome of women with index smear showing mild dyskaryosis: effects of age and evidence of HPV infection. Surprisingly, the mechanism of pathogenesis does not involve increased oxidative stress. Prior to the development of cardiomyopathy, Irx4(Delta ex2/Delta ex2) hearts had abnormal ventricular gene expression: Irx4-deficient embryos exhibited reduced ventricular expression of the basic helix-loop-helix transcription factor eHand (Hand1), increased Irx2 expression, and ventricular induction of an atrial chamber can you take zyrtec with cold and flu medicine -specific transgene. Expression of the mammalian homolog was detected in the adult testis. However, findings show that personality did not influence this effect, although neuroticism was associated with negative mood. In the absence of Erf4, the rate of hydrolysis of the active site palmitoyl thioester intermediate is increased, resulting in reduced palmitoyl transfer to a Ras2 substrate. However, many different molecules of potential therapeutic benefit are being investigated.

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