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Alcalm (Alprazolam)

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Alprazolam, available under the trade name Xanax, is a potent, short-acting benzodiazepine anxiolytic—a minor tranquilizer. It is commonly used for the treatment of anxiety disorders, especially of panic disorder, but also in the treatment of generalized anxiety disorder (GAD) or social anxiety disorder. It was the 12th most prescribed medicine in the United States in 2010. Alcalm, like other benzodiazepines, binds to specific sites on the GABAA receptor. It possesses anxiolytic, sedative, hypnotic, skeletal muscle relaxant, anticonvulsant, amnestic, and antidepressant properties. Alcalm is available for oral administration as compressed tablets (CT) and extended-release capsules (XR).

Other names for this medication:
Aderta, Alpam, Alpanol, Alpracon, Alprax, Alprazolam, Alprogard, Alprowon, Anxico, Anxilam, Anxizam, Anzilum, Azolam, Benzolam, Besquil, Betapax, Cardilax, Depten, Exprex, Flunix, Fluxozam, Kaprolam, Mediprex, Norex, Orten, Plaxid, Romipraz, Samprex, Setlan, Stresnil, Tenan, Tenfree, Tenolam, Tenschem, Tenscure, Tensyn, Trika, Welnorm, Zedel, Zenax, Zocam, Zolam, Zolark, Zolin, Zolran, Zolyde, Zopain, Zopral, Zorest

Similar Products:
Chloromycetin, Compazine, Coumadin, Flagyl, Duphaston, Starlix

Also known as: Alprazolam


{name} (alprazolam) is a benzodiazepine (ben-zoe-dye-AZE-eh-peen). It is thought that alprazolam works by enhancing the activity of certain neurotransmitters in the brain.

{name} is used to treat anxiety disorders and anxiety caused by depression.

{name} is also used to treat panic disorders with or without a fear of places and situations that might cause panic, helplessness, or embarrassment (agoraphobia).

It is dangerous to purchase {name} on the Internet or outside the United States. The sale and distribution of medicines outside the U.S. does not comply with safe-use regulations of the Food and Drug Administration (FDA). These medications may contain dangerous ingredients, or may not be distributed by a licensed pharmacy.


Usual Adult Dose for Anxiety:

Immediate-release tablets: 0.25 to 0.5 mg orally administered 3 times a day -Maximum dose: 4 mg/day

Usual Adult Dose for Panic Disorder:

Immediate-release tablets: 0.5 mg orally administered 3 times a day -Maximum dose: 10 mg/day Extended-release tablets: -Initial dose: 0.5 to 1 mg orally once a day -Maintenance dose: 3 to 6 mg orally per day, preferably in the morning -Maximum dose: 10 mg/day Comments: -The lowest possible effective dose should be administered and the need for continued treatment reassessed frequently. -Dosage should be reduced gradually when discontinuing therapy or when decreasing the daily dosage. -The daily dosage may be decreased by no more than 0.5 mg every 3 days; however, some patients may require an even slower dosage reduction. -The dose of extended-release tablets may be increased at intervals of 3 to 4 days in increments of no more than 1 mg per day. -The times of administration should be distributed as evenly as possible throughout the waking hours.

Usual Geriatric Dose for Anxiety:

Elderly or debilitated patients: Immediate-release tablets: 0.25 mg orally administered 2 or 3 times a day.

Usual Geriatric Dose for Panic Disorder:

Elderly or debilitated patients: Immediate-release tablets: -Initial dose: 0.25 mg orally administered 2 or 3 times a day Extended-release tablets: -Initial dose: 0.5 mg orally once a day Comments: -If side effects develop, the dose may be lowered. -The lowest possible effective dose should be administered and the need for continued treatment reassessed frequently. -Dosage should be reduced gradually when discontinuing therapy or when decreasing the daily dosage.

Detailed Alcalm dosage information


Seek emergency medical attention if you think you have used too much of this medicine. An overdose of Alcalm XR can be fatal.

Overdose symptoms may include extreme drowsiness, confusion, muscle weakness, loss of balance or coordination, feeling light-headed, fainting, and coma.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

It is very important to protect the orally disintegrating tablets from moisture. Remove and throw away any cotton packaging from the medicine bottle when you first use the medicine.

Detailed Alcalm dosage information

Side effects

The most common side effects associated with Alcalm are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

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Endovascular volume during vascular surgery training has increased profoundly over recent decades, providing heavy exposure to ionizing radiation. A liver biopsy, carried out after endoscopic sclerotherapy, revealed that granulomas primarily affected the portal area without fibrotic and cirrhotic changes, which is considered a primary cause of portal hypertension and esophagogastric varices. Amygdala connectivity differs among chronic, early course, and individuals at risk for developing schizophrenia. Laboratory trials with Bacillus thuringiensis serotype H-14 in controlling mosquito larvae. Cystoid macular edema in gyrate atrophy of the choroid and retina: a fluorescein angiography and optical coherence tomography evaluation. Rapid and simple mutation screening of G(M1) gangliosidosis in Shiba dogs by direct amplification of deoxyribonucleic acid from various forms of canine whole-blood specimens. We have observed that IL-8 is elevated in the peritoneal fluid of women with endometriosis and the levels correlate with the severity of the disease. Asparagine synthetase deficiency detected by whole exome sequencing causes congenital microcephaly, epileptic encephalopathy and psychomotor delay.

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Dimensional reduction: a design tool for new radiation detection materials. Influence of biotin supplementation on pig claw horn: a scanning electron microscopic study. This is, probably, due to an L-tyrosine-induced competitive inhibition of the L-DOPA transport to monoenzymatic AADC neurons after its release from the monoenzymatic TH neurons. Primary thyroid lymphoma: case series with review of literature. We have assessed a panel of antibodies that may help to distinguish between neoplasms from these two sites.

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Reverse transcriptase inhibitors alter uncoupling protein-1 and mitochondrial biogenesis in brown adipocytes. The present study showed that when NPE occurs, a high lung AngII concentration was associated with an imbalance between ACE mRNA to ACE2 mRNA expression level. In this retrospective study, we explored the role of CTC counts as predictors of disease evolution in breast cancer patients with limited metastatic dissemination. Somatostatin content may define a widespread subclass of GABAergic neurons in mammalian cerebral cortex. With the help of thick transparent transversal-sections in one of 14 fetal wrists manufactured by plastination histology we found the first compartment with two tendons of the abductor pollicis longus and dorsal of this compartment a connective tissue formation and a separate compartment for the extensor pollicis brevis tendon, proved as a primary anatomical disposition. To evaluate the regulatory potential of genetic loci controlling Mycobacterium butyricum adjuvant-induced arthritis (Mbt-AIA) using mono- and polycongenic rats. The French national observatory for epidemiology of bacterial resistance to antibiotics (ONERBA) includes numerous networks for the surveillance of bacterial resistance to antibiotics. Radical second resection provides survival benefit for patients with T2 gallbladder carcinoma first discovered after laparoscopic cholecystectomy.

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Successful live births after surgical treatments for symptomatic cesarean scar pregnancies: report of 3 cases. Short bowel syndrome poses a great challenge to pediatric teams. Increased c-fos gene expression in alpha motoneurons in rat loaded hindlimb muscles with inclined locomotion. Occupational exposure to hop dust is associated with respiratory disease. It is found that, upon circularly polarized photoirradiation, the diffraction efficiency of the fabricated Fresnel lens was increased significantly in a reversible manner. We found the domineering nonautonomy of frizzled clones was not altered when the clone cells were simultaneously mutant for inturned, multiple wing hairs, or dishevelled but it was blocked when the entire wing was mutant for inturned, fuzzy, multiple wing hairs, or dishevelled.

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Tetrahydrobiopterin metabolism in chronic uraemia: possible explanation of dialysis encephalopathy. The DBD interacts preferentially with branched DNA structures in vitro. The aim of this study was to determine appropriate guidelines for knee MRI administration using the RAND Appropriateness Method (RAM)-2013. Changing Italian nosocomial-community trends and heteroresistance in Staphylococcus aureus from bacteremia and endocarditis. The simulations indicate that the BLYP-D2 description with the TZV2P basis set underpredicts the saturated vapor densities and overpredicts the saturated liquid densities and critical and boiling temperatures for both compounds. Low levels of 4-ABP exposure have been associated with non-smoking-related bladder cancer. A comparative immunopathological and electron microscopic study of vasculitis and glomerulonephritis in autoimmune mice (B/W F1, SL/Ni, MRL/1) was performed. The solid-state reaction involves mix-grinding dry powders of beta-tricalcium phosphate powder (TCP) and either calcium hydroxide (Ca(OH)2) or calcium carbonate (CaCO3) or combination thereof, from pure commercial chemicals or derived from natural limestone or from seashells, of total calcium/phosphorus molar ratio between 1.5 to 2.0, to particle size of less than 10 microns, and firing the resultant powder to temperature between 600 degrees C - 1250 degrees C in atmosphere or in controlled atmospheric condition. As in other osteotropic cancers, both angiogenesis and the epithelial-to-mesenchymal transition play a crucial role in skeletal colonization, with the cooperation of additional factors including vascular endothelial growth factor, transforming growth factor beta, platelet-derived growth factor, insulin-like growth factors I and II, bone morphogenetic proteins, secretory protein clusterin, and others.

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To test the systemic and cardiac consequences of ovarian hormone deprivation, ovariectomy was induced in young female rats that were submitted or not to HT. Chlamydia pneumoniae is a significant cause of both upper and lower respiratory tract infections. Traumatic posterior root tear of the medial meniscus in patients with severe medial instability of the knee. By identifying different peaks for the analyzed samples, their chemical composition can be rapidly determined. The antiamnestic effect of tyramine and adrenaline is antagonized by the simultaneous administration of prazosin or yohimbine, but not by that of propranolol. The authors made a survey of a rural hospital emergency room to determine the types of foot injuries seen and the frequency of foot injuries in relation to total emergency room visits. Recent observations have established a complex signaling interplay between Ras and other members of the family. We identified 30 patients with 30 acetabular fractures who had been treated by this technique between 1995 and 2004. In this work, we focus on these structural properties, comparing them between different organisms and assessing their ability to describe the core promoter. Use of alcohol in the elderly: transcultural validation of the Michigan Alcoholism Screening Test - Geriatric Version (MAST-G).

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Aerobic treadmill plus Bobath walking training in moderately affected stroke patients was better than Bobath walking training alone with respect to the improvement of walking velocity and capacity. We propose what drugs does klonopin interact with that the extent of theta-gamma synchronization can be used to estimate the working-memory ability. This study supports teeth clipping of sucking pigs because there are welfare, production and financial benefits including reduced facial damage and preweaning mortality. Factors affecting thermodynamic stabilities of RNA 3 x 3 internal loops. A vulnerability model, in which perfectionism affects depressive symptoms, was compared to a scar model, in which depressive symptoms affects perfectionism, and to a reciprocal-causality model, in which both constructs concurrently affect each other across time.

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Gene expression in relation to exhaled nitric oxide identifies novel asthma phenotypes with unique biomolecular pathways. In vivo detection of applied electric currents by magnetic resonance imaging. Anthocyanidins, novel FAK inhibitors, attenuate PDGF-BB-induced aortic smooth muscle cell migration and neointima formation. A 34-year-old male presented with a 5-month history of fatigue, anorexia, low fever, night sweats, and oliguria with edema of the eyelid, exacerbated by abdominal distension and mild diarrhea of 3 weeks duration. Suppression of histamine-induced adrenocorticotropic hormone release by antihistamines and antidepressants. Ultraviolet light-induced yellowing of dental restorative resins. Given the rapid tissue accumulation of glycerol, dose-dependent decrease in brain growth, and lack of IVH effect on measured outcomes, we question the validity of this model because glycerol toxicity cannot be ruled out. Psychophysiological response to virtual reality and subthreshold posttraumatic stress disorder symptoms in recently deployed military.

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Subsequent laboratory examinations showed that serum alkaline phosphatase, gamma-glutamyl transpeptidase, C-reactive protein, and soluble interleukin-2 receptor levels were 3,078 IU/l, 510 IU/l, 20 mg/dl, and 7,290 U/ml, respectively. Magnetically coupled micromanipulator for use within a sealed chamber. The subjects were healthy and had full dental arches and no orofacial pain. Pathological score for the evaluation of allograft rejection in human hand (composite tissue) allotransplantation. Identification of risk factors might serve for preventing the appearance of this co-morbidity. An attempt to classify the most famous of biomaterials based on their physico-chemical and biological properties, as well as identified trends in the further development of tissue engineering and its importance in traumatology and orthopedics. A split calvarial frontal bone can you drink alcohol 2 days after taking flagyl graft was used to reconstruct the orbital roof. Side shift exercise for idiopathic scoliosis after skeletal maturity.

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Utility of cycle ergometer stress testing as a measure to assess health status and physical functioning for elderly people. Here we have used PCR DNA sequence analysis from multiple segments of DNA amplified directly from blood or necropsy tissue samples of six more selected cases of hemorrhagic disease to partially characterize four other types of EEHVs from either Asian or African elephants. Transcriptome network analysis reveals potential candidate genes for ankylosing spondylitis. Eligible guidelines were assessed by three reviewers using the Appraisal of Guidelines for Research and Evaluation (AGREE II) Instrument. Mineralocorticoid receptors in the heart: lessons from cell-selective transgenic animals. Together, these studies suggest that the TGF-beta signal transducer, Smad3, is required for the development of experimental OB in transplanted tracheas. Disseminated intravascular coagulation is associated with a high mortality rate, with patient outcomes largely dependent upon swift recognition and appropriate management of events. Atorvastatin reduces proinflammatory markers in hypercholesterolemic patients. A sclerosing stromal tumor of the ovary with masculinization in a premenarchal girl.

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Genetic linkage analysis of oral lichen planus in a Chinese family. With the nested set of crossover DNA samples and appropriate cloning techniques, this tightly linked marker can be used to clone the quaking locus. A debriefing questionnaire was administered to determine patient acceptability and understanding lasix dosage dogs congestive heart failure . Yet, modality-shift costs occur when subjects switch between response modalities. Fostering research in nursing practice: clinical leadership in action.

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Effect of photolytically generated hydroxyl radicals on the nucleation of ammonium chloride from aqueous solution. First, we aim to provide clear examples on the applications and zithromax antibiotic cats benefits of the use of proteomics in all aspects related to APH. Multinomial logistic regression was used to characterize the groups using socio-demographic and psychiatric covariates. Analysis of sulphation patterns indicates that heparan sulphate and heparin are separate families of N-sulphated polysaccharides. This group of patients do not benefit from complete axillary lymph node dissection. However, reliable predictive models are lacking for resource-limited prehospital settings such as those in developing countries like South Africa. For example, it is often assumed that colony-forming cells represent epidermal stem cells, although this has not proved to be the case in hematopoietic cell lineages. The crossover time from an exponential to a power law is also predicted. Two closely related sponge color morphs have been described, one inside caves and at their entrance (white/pink), and one on the rocky cliffs (violet). Dose-dependent effect of dehydroepiandrosterone, but not of its sulphate ester, on angiogenesis.

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To compare the variability and sample size requirements of the global quality-of-life (QOL) scores of the following three major QOL instruments: the Functional Assessment of Cancer Therapy-General (FACT-G), Functional Living Index-Cancer (FLIC), and European Organisation for Research and Treatment of Cancer Core Quality of Life Questionnaire C30 (EORTC QLQ-C30). Patch testing has been used as confirmatory testing in patients with extensive cutaneous reactions. The optimal stimulation site for electroventilation was first determined using hand-held, stimulating electrodes. Combined, our results highlight the impact of APC/C(C) (dh1) on the maintenance of genome integrity and show that this is, at least partially, achieved by controlling CtIP stability in a cell cycle- and DNA damage-dependent manner. Radiation sensitivity of human primary MSCs from healthy volunteers and primary human fibroblast cells was examined, and cellular morphology, cell cycle effects, apoptosis, and differentiation potential after exposure to IR were assessed. These findings demonstrate that the A1330V and V667M polymorphisms are associated with low BMD in peri- and postmenopausal Greek women. Sagittal imbalance cascade for simple degenerative spine and consequences: algorithm of decision for appropriate treatment. Decision making and decision support for hereditary breast-ovarian cancer susceptibility. Of notice, in all cases, morphological features suggesting hyaline-vascular Castleman disease were recognized in the interfollicular areas, containing scattered epithelioid cells similar to those found in the nodules, thus providing a useful clue for FDCS diagnosis.

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To investigate, in pregnant OW/OB women, the longitudinal changes of adiponectin plasma levels, carbohydrate and lipid metabolism, and to identify if there is any association between adipokines and subsequent development of GDM. Inhibition of CaV2.3 channels by NK1 receptors is sensitive to membrane cholesterol but insensitive to caveolin-1. The delta 4 acetylenic acids are therefore useful tools for investigating the function and action of LTC4 and LTD4. The aim of our study was to monitor a panel of cytokines extracted from the bronchoalveolar lavage (BAL) during the first year after LT and correlate them with clinical ALR. Long-term hormone replacement therapy is associated with an increased breast cancer risk. Plants, symbiosis and parasites: a calcium signalling connection.

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An examination of a widely used commercially available large pore (100kDa MWCO) polymeric microdialysis probe, the CMA/20 (polyethersulfone) over 6 days of continuous microdialysis showed that: (1) published molecular weight cut-off values may not predict the size of proteins that can be recovered. Calliper measurements and CT scan analysis were undertaken to determine the optimum positions in obtaining a 5-mm-thickness tricortical graft whilst remaining safe for the LFCN. The charts of all patients who had undergone CXL because of a worsening corrected distance visual acuity (CDVA) and/or diurnal visual fluctuations after RK were reviewed retrospectively. In this study a modification of the equation has been suggested to take into account the changes in the heat capacities that result due to high temperature effects. Fluoride accumulation and distribution in mulberry insects near fluoride pollution sources. Compound 2 was distributed mainly in the muscle and fatty tissue. A reduction in examination anxiety after beta-blocker intake could not be demonstrated with a multi-level test model (which included the parameters self-rated anxiety, motor behaviour, task performance and physiology), although pulse rates were lowered significantly. Sexual systems are highly variable in flowering plants and an important contributor to floral diversity.

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The application of this method to the numerical investigation of motion and aggregation of red blood cells in two-dimensional microvessels is discussed. By contrast the construct validity of the questionnaire was satisfactory. Our findings suggest that SFS allows for the greater understanding of protein fibers in solution, which is important when, for example, designing scaffolds in tissue engineering or developing cures for diseases associated with protein fibers. The prevalence of type 2 diabetes mellitus is increasing worldwide with obese diabetic patients constituting the majority of this population. CMECs were cultured under normal (5.5 mmol/l) or high glucose (22 mmol/l) concentrations for 7 days. pylori isolates from family members by multi-locus sequence typing (MLST) and identified the original strain infecting the index child. Acute respiratory infections largely caused by viruses, are the most common illnesses experienced by otherwise healthy adults and children. GM1b and GD1a were more prominent in AR-negative than in AR-positive cells. The respiratory complex I couples the electron transfer from NADH to ubiquinone with a translocation of protons across the membrane.

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