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Alfacal (Calcitriol)

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Alfacal is a man made form of vitamin D. It helps your body keep the proper levels of calcium and phosphorus and maintain healthy bones and teeth. Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Take your medicine at regular intervals. Do not take your medicine more often than directed.

Other names for this medication:
Admax, Alcee, Alfabond, Alfacal, Alfacalcirol, Alfacip, Alfarich, Alphadol, Apcical, Aristrol, Biocitral, Calbory, Calcibest, Calcicare, Calcigra, Calcit, Calcitriol, Calcor, Caltin, Carcal, Cholical, Coecoral, Duracal, Koncal, Kurecal, Laretol, Minroset, Netxod, Novadee, Primacal, Qpcal, Riecal, Ritoca, Rolsical, Septriol, Statbone, Tobalt, Trolec, Vezocal, Vitalpha, Zaxial

Similar Products:
Prandin, Mestinon, Antivert, Priligy, Lexapro, Ultram, Dilantin

Also known as: Calcitriol


Generic Alfacal is a synthetic vitamin D analog which is active in the regulation of the absorption of calcium from the gastrointestinal tract and its utilization in the body. The two known sites of action of Generic Alfacal are intestine and bone. Generic Alfacal receptor-binding protein appears to exist in the mucosa of human intestine. Additional evidence suggests that Generic Alfacal may also act on the kidney and the parathyroid glands. Generic Alfacal is the most active known form of vitamin D3 in stimulating intestinal calcium transport. In acutely uremic rats Generic Alfacal has been shown to stimulate intestinal calcium absorption. The kidneys of uremic patients cannot adequately synthesize Generic Alfacal, the active hormone formed from precursor vitamin D. Resultant hypocalcemia and secondary hyperparathyroidism are a major cause of the metabolic bone disease of renal failure. However, other bone-toxic substances which accumulate in uremia (eg, aluminum) may also contribute. The beneficial effect of Generic Alfacal in renal osteodystrophy appears to result from correction of hypocalcemia and secondary hyperparathyroidism. It is uncertain whether Generic Alfacal produces other independent beneficial effects. Alfacal is also known as Calcitriol. Generic Alfacal treatment is not associated with an accelerated rate of renal function deterioration. No radiographic evidence of extraskeletal calcification has been found in predialysis patients following treatment. The duration of pharmacologic activity of a single dose of calcitriol is about 3 to 5 days. Generic name of Generic Alfacal is Calcitriol. Brand name of Generic Alfacal is Alfacal.


Generic Alfacal is available in capsules (0.25 mcg) and liquid form. Capsules must be swallowed whole. Do not crush or chew them. If you are prescribed the liquid form, use as directed. Follow dosing instructions closely. Do not take this medication with mineral oil or magnesium containing antacids which may reduce its effects. Foods rich in vitamin D include: fortified dairy products, eggs, sardines, cod liver oil, chicken livers and fresh-water fish. Vitamin D is also obtained from periodic exposure to the sun. It is important to maintain a well-balanced diet while taking this medication. Calcium supplements may be recommended in addition to this medication. If you want to achieve most effective results do not stop taking Generic Alfacal suddenly.


If you overdose Generic Alfacal and you don't feel good you should visit your doctor or health care provider immediately.


Keep out of the reach of children.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Do not keep outdated medicine or medicine no longer needed.

Side effects

The most common side effects associated with Alfacal are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Tell your doctor if you have ever had any unusual or allergic reaction to medicines in this group or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

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In multivariate analyses adjusted for probing depth, plaque and calculus, smokers appeared to be at higher risk for the transition from non-bleeding to bleeding on probing. The aim of the eye care project is to clear the backlog of cataract blindness for the people of Gaur and its surrounding districts in southeast Nepal. Smoking control programs are needed in Bangladesh to improve health and nutrition of the people who are already nutritionally deficient. Computerized assessment of voluntary control in the shift of the center of pressure: a pilot study. Treatment with cefrom (cefpirom) in severe urological infections. Developmental biologists have been intrigued by the mechanism of hypselodonty since it requires the maintenance of continuous crown formation during development via stem cell niche activity. We are presenting two cases of giant pyogenic granuloma, one, in a 28-year-old adult, presenting as a giant fluffy swelling of scalp and the other in a 11-year-old child, presenting as a giant ulcerated globular swelling of the scalp. These data indicate that RLN are essential in the development of tumor immunity and may be used as a source of therapeutic effector cells for adoptive immunotherapy. There was no evidence of blood or bone marrow involvement suggestive of acute leukemia. Diabetes mellitus (DM) is a metabolic disorder very common worldwide.

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BCL6 is a zinc-finger transcriptional repressor, which is highly expressed in germinal centre B-cells and is essential for germinal centre formation and T-dependent antibody responses. RA patients included in the study met the 2010 ACR/European League Against Rheumatism (EULAR) criteria, were receiving stable doses of steroids and had not received rituximab in the previous year. This pullout model makes it possible to study the kinetics and strength of bone bonding with negligible influence of shear forces or mechanical interlocking. Lysine acetylation sites in bovine foamy virus transactivator BTas are important for its DNA binding activity. In this study, the susceptibility values of 5 regions of interest in the human brain were measured on 9 healthy subjects following calibration by using phantom experiments. TEM analysis revealed gold nanoparticles within AuNP-treated stratum corneum. Histologically, the posterior capsule opacification (PCO) corresponds to regenerative tissue of transformed lens epithelial cells (LECs) with extracellular matrix production. Consistent with its proposed microsomal origin, LPGAT1 was localized to the endoplasmic reticulum by subcellular fractionation and immunohistochemical analyses.

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Interaction between the microtubule inhibitor tubulozole and gamma-irradiation in murine tumors in vivo. Reduced low forced expiratory volume in 1 second (FEV1) is reportedly associated with an increased risk of atrial fibrillation (AF). Integrative data mining highlights candidate genes for monogenic myopathies. In the 32-cell embryo, the vegetal-most tier 4 cells are able to induce dorsal development in the overlying, equatorial tier 3 cells (R.L. These findings are discussed in relation to the processing of flavivirus polyproteins. Experimental transmission of Actinobacillus seminis infection to rams. Age-related balance impairments, particularly in mediolateral direction (ML) may cause falls.

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Fatty acid esters of 17beta-estradiol (E2) are estrogen metabolites associated with lipoproteins in blood. It contains an ORF with length of 1191bp, encoding a protein with a signal peptide sequence and galactosyl-T domain, and its molecular weight and isoelectric point is predicted to be 43.3 kDa and 8.67 respectively. Surgical correction of the varus position of the 1st metatarsal bone. Drawing upon two studies by the Rehabilitation Engineering Research Center on Workplace Accommodations, we expound on employee-side considerations in the implementation of telework. To explain the influence of parental monitoring on adolescent sexual initiation within the context of a cognitive behavioral model.

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Abnormality of odd-numbered long-chain fatty acids in erythrocyte membrane lipids from patients with disorders of propionate metabolism. Treatment with follicle regulatory protein significantly slowed the rate of tumor growth with both treatments. Pulmonary alveolar proteinosis is a rare disease characterized by the deposit of lipid-rich proteinaceous material in alveolar spaces. Diagnosis of either anomalous trichromacy or dichromacy was performed using a Nagel Type I anomaloscope. HE proteins mediate reversible binding to sialic acid receptor determinants, very abundant glycan residues in the enteric and respiratory tracts. Filler injection enhances the projection of the reconstructed nipple: an original easy technique.

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Laser-induced birefringence patterns which break the symmetry of the experimental setup have been observed in a low molar mass anisotropic glass with nematic orientational order under a polarizing microscope. Discrimination of Chinese teas with different fermentation degrees by stepwise linear discriminant analysis (S-LDA) of the chemical compounds. Insights into the Mechanisms of the Therapeutic Efficacy of Alemtuzumab in Multiple Sclerosis. The objective of this study was to analyse mortality in migrants from Finland to Sweden. This leads to the retention of not only other lipids, but also of transmembrane proteins that transiently associate with the late endosomes (LE) in normal cells, on their way to other cellular destinations such as the trans-Golgi network (TGN).

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Relationship between occupation of cerebral H1-receptors and sedative properties of antihistamines. The levels of MMP-9 and fibronectin, but not those of MMP-2, were significantly higher in tumour tissues and in the ascites fluid of the recurrent patient group and the patient group who did not survive, as compared to the non-reccurent cases. Therefore, treatments that alleviate the burden of depression without increasing seizure risk or, better yet, with the possibility of improving seizure control are worth exploring. Therapy-related acute myeloid leukemia in a child with Noonan syndrome and clonal duplication of the germline PTPN11 mutation. We conducted a systematic PubMed search to identify studies examining risk factors for health effects of precipitation-related floods, among Organisation for Economic Co-Operation and Development (OECD) member countries. Using random effects model, no significant association was found in the ten TLR4 SNPs reported by at least four included studies under any inheritance model (rs2737191, rs1927914, rs10759932, rs1927911, rs11536879, rs2149356, rs4986790, rs11536889, rs7873784, and rs1554973).

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Genome scanning of the HXB/BXH sets of recombinant inbred strains of the rat for quantitative trait loci associated with conditioned taste aversion. At dpi 2, bacterial burdens in the lungs were similar between TLR4(d) and WT mice, but TLR4(d) mice surprisingly harbored approximately 10-fold fewer bacteria in their spleens and livers. We conclude that the suppression of spontaneous bursting or beating pacemaker activity in neuron R15 by FMRFamide is due to a decrease in the subthreshold calcium current. In this paper, we provide evidence to suggest that vitamin D3 acts as an anti-inflammatory agent and reverses the age-related increase in microglial activation and the accompanying increase in IL-1beta (interleukin-1beta) concentration. So we hypothesize that chronic intermittent low-level tragus stimulation (LL-TS) could attenuate LV remodeling in conscious dogs with healed MI.

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The tumor was diagnosed as a sarcomatoid renal cell carcinoma with overgrowth of the sarcomatoid component (World Health Organization: renal cell carcinoma, unclassified). Characterization is based on information obtained from a specific image analysis method applied to continuous sequences of microscopical images. Transformation of Chlamydia trachomatis should greatly advance the chlamydial research. In chromosomal females, expressing a tra or Sxl mutation, the gustatory system is transformed toward the male phenotype. High-quality measurements of MNCH coverage are essential for tracking progress and making evidence-based decisions. However, epidermal growth factor, fibroblast growth factor, and the tumor promoter tetradecanoyl phorbol acetate have a negligible effect. Calcium use in the management of osteoporosis: continuing questions and controversies. The signal peptide was found to specifically bind SecY in a saturable manner and at levels comparable to those that stimulate SecA ATPase activity. These studies yielded a single prominent mGluR7 CT-associated protein of 55 kDa, which subsequent microsequencing analysis revealed to be alpha tubulin.

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Alternative diagnostic and treatment measures of salivary gland fistulas are discussed. Using cone beam computed tomography to detect the relationship between the periodontal bone loss and mucosal thickening of the maxillary sinus. Two independent mechanisms for motion-in-depth perception: evidence from individual differences. Mosquitoes were sensitive to snake toxic or neurotoxic phospholipase A2 enzymes (but not to nontoxic phospholipase A2 enzymes), cobrotoxin, saxitoxin, microcystin and the scorpion insect sodium channel toxin. This is because solid masses typically have distinct stiffnesses compared to the surrounding normal tissue. The persistent hypocalcemia, apart of its acute repercussions, produces severe neurologic consequences.

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The aim was to evaluate the effects on acid-base status and serum phosphate of a regional citrate anticoagulation (RCA) protocol for continuous veno-venous hemofiltration (CVVH) combining the use of citrate with a phosphate-containing replacement fluid. Mitochondria cooperate with their host cells by contributing to bioenergetics, metabolism, biosynthesis, and cell death or survival functions. In the striatum of adalat medication Meth-sensitized rats, phosphothreonine-DARPP-32 immunoreactivities significantly increased, but DARPP-32 immunoreactivities were not significantly different from those of the control rats. Spatial distribution of insulin-like growth factor binding protein-2 following hypoxic-ischemic injury. J-point elevation, ST-elevation, and T-wave changes documented in the last sinus beat prior to ventricular extrasystoles are in agreement with phase 2 reentry, suggesting that this may be the responsible mechanism for ventricular extrasystoles and ventricular tachycardia/fibrillation. Assessment took place before and after the completion of a 14-week training program. SnRK2.6 is more important for overall stomatal control, while SnRK2.2 and SnRK2.3 are more important for implementing GC stress memory in the subsequent dehydration response. Thus, there is no need for replications and we obtain a continuous process in the limit. These results suggest that gender differences in VAT reduction during weight loss are independent of changes in FM. Cyclic adenosine monophosphate and cyclic guanosine monophosphate variations during isometric tetanus in frog sartorius muscle.

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Since the cellular functions of Rac3 have not been defined, constitutively active V12Rac3 was used to identify targets that transduce its signals. A set of test signals consisting of generic synthetic signals, simulated biomedical signals, and real RR records was created. An increase in hydration had little effect on the T(1rho) values of pure lysozyme, trehalose, lactose, trehalose-lysozyme, and lysozyme at low lactose concentrations. Chyluria is generally the result of parasitic infection and is extremely rare in Europe. Children of mothers diagnosed with serious mental illness: patterns and predictors of service use. Rat bone marrow MSCs were isolated from healthy rats and cultured in vitro.

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Exposure to potentially harmful drug-disease interactions in older community-dwelling veterans based on the Healthcare Effectiveness Data and Information Set quality measure: who is at risk?. The current study aimed to examine the underlying relationships between neurological soft signs and neurocognition in a group of healthy elderly. We publish here descriptions of the excitatory sensory responses and receptive field properties of the visual, auditory, somatosensory and multisensory caudate nucleus and substantia nigra pars reticulata neurons. These data suggest a separate neuroeffector/receptor mechanism for quisqualate compared to L-glutamate, L-aspartate and N-methyl-D-aspartate. Consistently, PAT also abolished the vascular endothelial cell growth factor-induced angiogenesis in the Matrigel plugs assay. In many cases, a gap still exists between best evidence and routine practice and pregnant women and neonates continue to experience preventable harm. The implications of this interplay will be also discussed in this review. In this paper, expected problems are discussed, leading to the conclusion that it will be difficult to achieve comprehensive analysis down to the concentrations presently considered safe, but that systematic work should start to define the possibilities and limitations of analytical chemistry for a migrate-oriented coating legislation. The incubation effect in rats: skin resistance changes after footshock. Under base-case assumptions (no herd immunity and no serotype replacement) the programme is not expected to be cost-effective from the NHS perspective at the current price of the vaccine (assumed 30 pounds per dose, three-dose programme).

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A lipid emulsion administered orally to rats with (-)-epigallocatechin gallate at a dose of 100 mg/kg resulted in the increase in plasma triacylglycerol being significantly inhibited after 1 and 2 h compared to the case without (-)-epigallocatechin gallate. The best support for the hypothesized involvement of central nervous system dopamine systems in zithromax dosage pediatric the pathophysiology of schizophrenia is the association between the affinity of neuroleptic drugs for the D2 dopamine receptor and their potency as antipsychotics. Functionalization of robust Zr(IV)-based metal-organic framework films via a postsynthetic ligand exchange. There was a significant association of AC with MG especially for ocular or seronegative MG in cases without thymoma. We sought to determine the rate and timing of adverse events that occur during preinduction cervical ripening using the Foley catheter before extrusion of the balloon and institution of oxytocin. We treated six MM cell lines, representative of different histotypes (epithelioid, biphasic, and sarcomatoid), with cisplatin in combination with MK-1775, an inhibitor of the G 2/M checkpoint kinase WEE1.

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