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Alparazole (Alprazolam)

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Alprazolam, available under the trade name Xanax, is a potent, short-acting benzodiazepine anxiolytic—a minor tranquilizer. It is commonly used for the treatment of anxiety disorders, especially of panic disorder, but also in the treatment of generalized anxiety disorder (GAD) or social anxiety disorder. It was the 12th most prescribed medicine in the United States in 2010. Alparazole, like other benzodiazepines, binds to specific sites on the GABAA receptor. It possesses anxiolytic, sedative, hypnotic, skeletal muscle relaxant, anticonvulsant, amnestic, and antidepressant properties. Alparazole is available for oral administration as compressed tablets (CT) and extended-release capsules (XR).

Other names for this medication:
Acalm, Alcalm, Alfix, Allam, Alpam, Alpraquil, Alprawin, Alprine, Alpronit, Alprose, Alprosym, Alzot, Ambulax, Anlzium, Anxicalm, Anxiflu, Anxigon, Anxit, Anxorel, Aryalam, Axizox, Azicalm, Balmusa, Depsolam, Dizeral, Esteem, Exprex, Faxtin, Fluxin, Fluzolam, Kurelam, Niravam, Orten, Pecalm, Pifzot, Prazil, Procalm, Prosanti, Samitol, Sertakem, Setex, Sinaday, Stresnil, Tensfree, Welnorm, Zocam, Zolark, Zoldac, Zolorest, Zolyde

Similar Products:
Aurogra, Altace, Eulexin, Moduretic, Vasotec, Lamisil, Cymbalta, Remeron, Thorazine

Also known as: Alprazolam


Alparazole is a benzodiazepine (ben-zoe-dye-AZE-eh-peen). Alprazolam affects chemicals in the brain that may be unbalanced in people with anxiety. Alparazole is used to treat anxiety disorders, panic disorders, and anxiety caused by depression.

You should not use Alparazole if you have narrow-angle glaucoma, if you also take itraconazole or ketoconazole, or if you are allergic to Alparazole or similar medicines (Valium, Ativan, Tranxene, and others).

Alprazolam may be habit-forming. Misuse of habit-forming medicine can cause addiction, overdose, or death.

Do not drink alcohol while taking Alparazole. This medication can increase the effects of alcohol. Alprazolam may be habit-forming and should be used only by the person for whom it was prescribed. Keep the medication in a secure place where others cannot get to it.


Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results.

Do not crush, chew, or break an extended-release tablet. Swallow the pill whole. It is specially made to release medicine slowly in the body. Breaking the pill would cause too much of the drug to be released at one time.

Measure the liquid form of Alparazole with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

Do not swallow the orally disintegrating tablets whole. Allow it to dissolve in your mouth without chewing.

Contact your doctor if this medicine seems to stop working as well in treating your panic or anxiety symptoms.

You may have seizures or withdrawal symptoms when you stop using Alparazole. Ask your doctor how to avoid withdrawal symptoms when you stop using Alparazole.

Keep track of the amount of medicine used from each new bottle. Alparazole is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription.


If you have been prescribed Alparazole for medical reasons, the best way to avoid a Alparazole overdose is to adhere to prescribed orders—closely monitor your dose and the time at which you take your medication. Track your Alparazole consumption in a notebook or on your phone. If you notice that you are taking a higher dose of the drug, taking the drug more often, or you want to consume more of the drug, talk with your doctor immediately.


Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details.

Side effects

The most common side effects associated with Alparazole are:

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Replicative study of GWAS TP63C/T, TERTC/T, and SLC14A1C/T with susceptibility to bladder cancer in North Indians. Concepts and supporting tools such as checklists for literature assessment have been developed and validated. A technique is described for a one-stage reconstruction of a large congenital defect of upper eyelid in a newborn. Overt hypothyroidism and myxedema coma always require treatment, but treatment of subclinical hypothyroidism is not as clear. The effect of OVA-DT on the production of allergen-specific Ig isotypes of the sensitized mice and the cytotoxic effect of OVA-DT on B cells expressing OVA-specific IgE were examined. It is suggested that reduced cytosolic acetaldehyde dehydrogenase activity may represent a primary defect in alcoholism and is, in part, the cause of the abnormal acetaldehyde metabolism in alcoholic patients. The ADX improved her hypertension with normalization of the plasma aldosterone concentration, but without adequately increasing her plasma renin activity. Density functional theory for hyperfine coupling constants with the restricted-unrestricted approach.

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Focusing on cardiovascular phenotypes, the learning procedure predicted known knockdown and mutant phenotypes with high precision. The effects of speed enforcement with mobile radar on speed and accidents. Butorphanol suppression of histamine itch is mediated by nucleus accumbens and septal nuclei: a pharmacological fMRI study. In both cases, the activating influence and the anti-tyrosine hydroxylase activity bound to the matrices and were eluted together. The construct validity of the scale was assessed in Study 2 by confirmatory factor analysis. We applied this method to explore an open question in preimplantation embryonic development.

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Retinal IR injury was induced by unilateral elevation of intraocular pressure and the level of Hmgb1 in vitreous humor was analyzed 24 hours after reperfusion. However, squalamine significantly blocked VEGF-induced activation of MAP kinase and cell proliferation in human vascular endothelial cells. Data from the 2005 National Survey of Children with Special Health Care Needs were combined with state characteristics to estimate a hierarchical generalized linear model of the association between state residence, Medicaid reimbursement rate and problems accessing care for children with special health care needs with and without autism. Effects of Solar Particle Event-Like Proton Radiation and/or Simulated Microgravity on Circulating Mouse Blood Cells. Malignancy of the sphenoid sinus is rare and metastasis from a cholangiocarcinoma (CC) to this location is even rarer. Reactive oxygen species (ROS) have been implicated in mediating 4HPR-induced apoptosis in various cancer cells, including head and neck squamous cell carcinoma (HNSCC) cells. The epidermal barrier function is dependent on the serine protease CAP1/Prss8. Involvement of presynaptic dopamine receptors in the antihypertensive response to 2-NN-dimethylamino-5,6-dihydroxy-1,2,3,4,-tetrahydronaphthalene (M-7). Centrally administered orexin A increases motivation for sweet pellets in rats.

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The control group consisted of 15 healthy volunteers matched by sex and age. No differences in the changes of health-related quality of life were found between the groups during follow-up. We investigated if a history of clinician-diagnosed sleep apnea or primary snoring was associated with LTL in later adulthood. To investigate whether patients with a history of placental abruption have an increased risk for subsequent maternal long-term morbidity. Some miRNAs are excellent disease biomarkers due to their abundance and cell-type specificity. Online faculty listings from 98 otolaryngology departments were organized by gender, academic rank, fellowship training status, and institutional location. Two patients with ESRD presented with acute ICH (one with putaminal hematoma, the other with bilateral subdural hematomas) and developed fatal/near-fatal herniation during HD, associated with malignant worsening of cerebral edema.

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The palladium-catalyzed cross-coupling reaction of carboxylic anhydrides with arylboronic acids: a DFT study. Transcriptional unit of the murine Thy-1 gene: different distribution of transcription initiation sites in brain. Previous fine mapping studies in Norwegian Red cattle (NRC) in the region 86-90.4 Mb on Bos taurus chromosome 6 (BTA6) has revealed a quantitative trait locus (QTL) for protein yield (PY) around 88 Mb and a QTL for clinical mastitis (CM) around 90 Mb. Older adults often have difficulty communicating sexual problems, concerns, and questions because of their conflicting attitudes and perceptions. The membrane-based SERS sensor shows high sensitivity and good reproducibility. Doppler echocardiographic evaluation of tilting-disc prosthetic heart valves in children.

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Although poor mental health in Thai women represents an obstacle for integration, the potential resilience indicated in the group with high social trust and without exposure to social isolation suggests that such aspects be included in the program designed to facilitate integration. The premise that lung function can regulate chest wall mobility is an accepted concept. Temperature dependence studies showed that spectral signal intensity of the fat resonance of the fibrous plaque increased while linewidth decreased with increasing temperature from 24 degrees C to 37 degrees C. At 12-month follow-up, the patient is in good clinical condition, with a small residual walking impairment and no clinical, laboratory, or imaging sign of aortic endograft infection. Recovery of intact 2-aminobenzamide-labeled O-glycans released from glycoproteins by hydrazinolysis. This was a prospective study conducted over a period of three years in patients of aneurysmal subarachnoid hemorrhage. The laparoscopic technique involves an isoperistaltic tube of 6-7 cm of length and 10-12 mm of diameter is created by 2 applications of linear stapling and cutting device. The spatial distribution and architecture of the biofilms were examined by scanning electron microscopy and confocal scanning laser microscopy. One of the hallmark findings in patients suffering from SARS (severe acute respiratory syndrome) is lymphopenia, which is the result of massive lymphocyte death.

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In the isolated rat pancreas perfused with glucose-free medium, HB 419 released glucagon beside insulin and somatostatin. Time course of rat motility response to apomorphine: a simple model for studying preferential blockade of brain dopamine receptors mediating sedation. Can the lumpy distribution of galaxies be reconciled with the smooth X-ray background?. High frequency of BRAF(V600E) in DNTs and SEGAs would be useful in the differential diagnosis, and also offers a potential specific treatment targeting BRAF(V600E) . In this cohort, responses to simple questions on the frequency of any physical activity and of strenuous activity asked at baseline were associated with hours spent on specific activities and the associated estimated excess MET-hours expended, reported 3 years later. Nerve growth factor attenuates neurotoxic effects of taxol on spinal cord-ganglion explants from fetal mice. The correlation between SPI and IPSS was investigated and each symptom was classified according to its frequency and according to the bothersomeness it induced. Salivary cortisol was collected from all participants during ambulatory conditions risperdal consta dosing conversion in response to reminders provided by portable mini-computers on 3 consecutive days every 2 h for 14 h after awakening.

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Lack of association of primary iron overload and common HFE gene mutations with liver cirrhosis in adult Indian population. Consistent with the presence of a high density of binding sites in the SFO and the ME of the rat brain, our results show an increase in PI hydrolysis induced by ETs in each structure, in a dose-dependent manner and with similar ED50 values. SSEPs were recorded by stimulating the median nerve, and the negative potentials elicited from the brachial plexus (N9), neck (N11, lcN13, ucN13), and somatosensory area (N18) were measured to determine interpeak latencies and then corrected latency. Furthermore, the antiepileptogenic effects of LEV in addition to antiseizure effects have been reported in the amygdala-kindling model in rats. A new study identifies homozygous missense mutations in SGOL1, which encodes a component of the cohesin complex, in a newly described disorder termed Chronic Atrial and Intestinal Dysrhythmia (CAID) syndrome. Routine standing lateral radiographs should be standard practice to identify DS, as nearly 1/3 of cases will be missed on supine MRI. Cellular evidence for selfish spermatogonial selection in aged human testes. Each volunteer then read a 5-minute script while reclined how many zyrtec pills can i take in a day in a standard ophthalmic examination chair with an open blood agar plate secured to the forehead to simulate bacterial dispersal associated with a talking patient.

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Randomized trial showing efficacy and safety of twice-daily remogliflozin etabonate for the treatment of type 2 diabetes. An excellent resolution of the two antipodes is obtained (Rs greater than 2) with high peak symmetries. Effects of dietary betaine supplementation subjected to heat stress on milk performances and physiology indices in dairy cow. Sarcoma of the abdominal aorta involving marginal arteries of the small intestine: a case report. Short-term exposure to ozone of elastase-treated rats revealed panacinar emphysema, including an inflammatory response in the centroacinar region. Usage of whey protein may cause liver damage via inflammatory and apoptotic responses. The three experiments indicate that even very simplistic images of fear-relevant animals can divert attention. Such collision tumours in the pituitary and adrenal as components of MEN syndrome have not been previously described. Caspase-12 also significantly increased at 1, 3, 6, 24, 48, and 72 h. PI correlated with homocysteine and interleukin-6, monocyte count, gender, age and BMI, with monocyte count and age being independent determinants for PI.

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Among patients hospitalized with acute cardiovascular disease, pneumonia, and major surgery, Asian and Hispanic patients had significantly higher rates of HAIs than white non-Hispanic patients. Isolation of Karelian fever agent from Aedes communis mosquitoes. High Id1 expression, a generally negative prognostic factor, paradoxically predicts a favorable prognosis for adjuvant paclitaxel plus cisplatin therapy in surgically treated lung cancer patients. The data suggest that changes in brain drug concentrations following hypophysectomy at least partially explain the behavioural alterations seen in this test situation. The overall reoperation rate attributable to identifiable device-related problems was 0.3 percent.

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Roentgenographically, an initial diffuse, pin-point micronodularity subsequently becomes associated with conglomerates, usually in the upper lobes, closely resembling the progressive massive fibrosis (PMF) of the pneumoconioses. A chemoselective switch between reaction pathways by an alcohol cosolvent effect in a general SmI2-mediated synthesis of uracil derivatives is described. An internet-based survey on the circumstances of food-induced reactions following the diagnosis of IgE-mediated food allergy. Mapping of B-cell epitopes in the nucleocapsid protein of Puumala hantavirus. Mosaics of ancient mitochondrial DNA: positive indicators of nonauthenticity. The superiority of combination beclomethasone and salbutamol over standard dosing of salbutamol in the treatment of chronic asthma. These include cardiomyopathy development and cardiac arrhythmias.

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