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Alpracon (Alprazolam)

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Alprazolam, available under the trade name Xanax, is a potent, short-acting benzodiazepine anxiolytic—a minor tranquilizer. It is commonly used for the treatment of anxiety disorders, especially of panic disorder, but also in the treatment of generalized anxiety disorder (GAD) or social anxiety disorder. It was the 12th most prescribed medicine in the United States in 2010. Alpracon, like other benzodiazepines, binds to specific sites on the GABAA receptor. It possesses anxiolytic, sedative, hypnotic, skeletal muscle relaxant, anticonvulsant, amnestic, and antidepressant properties. Alpracon is available for oral administration as compressed tablets (CT) and extended-release capsules (XR).

Other names for this medication:
Aleez, Almee, Alprawin, Alprax, Alprine, Alprocontin, Alpronit, Alprose, Alprowon, Alzopax, Anquil, Anxofit, Anzal, Betapax, Coolam, Destres, Ezoprax, Fludep, Flumusa, Fluxozam, Kurelam, Notence, Omelam, Onapract, Poize, Prazolam, Proprazolam, Resolin, Samrox, Tenschem, Tensyn, Tryzo, Zolipax, Zopam

Similar Products:
Azulfidine, Celexa, Daklinza, Lozol, Soma

Also known as: Alprazolam


{name} XR (alprazolam) is in a group of drugs called benzodiazepines (ben-zoe-dye-AZE-eh-peens). Alprazolam affects chemicals in the brain that may become unbalanced and cause anxiety.

{name} XR is used to treat anxiety disorders, panic disorders, and anxiety caused by depression.

{name} XR may also be used for other purposes not listed in this medication guide.


Usual Adult Dose for Anxiety:

Immediate-release tablets: 0.25 to 0.5 mg orally administered 3 times a day -Maximum dose: 4 mg/day

Usual Adult Dose for Panic Disorder:

Immediate-release tablets: 0.5 mg orally administered 3 times a day -Maximum dose: 10 mg/day Extended-release tablets: -Initial dose: 0.5 to 1 mg orally once a day -Maintenance dose: 3 to 6 mg orally per day, preferably in the morning -Maximum dose: 10 mg/day Comments: -The lowest possible effective dose should be administered and the need for continued treatment reassessed frequently. -Dosage should be reduced gradually when discontinuing therapy or when decreasing the daily dosage. -The daily dosage may be decreased by no more than 0.5 mg every 3 days; however, some patients may require an even slower dosage reduction. -The dose of extended-release tablets may be increased at intervals of 3 to 4 days in increments of no more than 1 mg per day. -The times of administration should be distributed as evenly as possible throughout the waking hours.

Usual Geriatric Dose for Anxiety:

Elderly or debilitated patients: Immediate-release tablets: 0.25 mg orally administered 2 or 3 times a day.

Usual Geriatric Dose for Panic Disorder:

Elderly or debilitated patients: Immediate-release tablets: -Initial dose: 0.25 mg orally administered 2 or 3 times a day Extended-release tablets: -Initial dose: 0.5 mg orally once a day Comments: -If side effects develop, the dose may be lowered. -The lowest possible effective dose should be administered and the need for continued treatment reassessed frequently. -Dosage should be reduced gradually when discontinuing therapy or when decreasing the daily dosage.

Detailed Alpracon dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of alprazolam can be fatal.

Overdose symptoms may include extreme drowsiness, confusion, muscle weakness, loss of balance or coordination, feeling light-headed, and fainting.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

It is very important to protect the orally disintegrating tablets from moisture. Remove and throw away any cotton packaging from the medicine bottle when you first use the medicine.

Detailed Alpracon dosage information

Side effects

The most common side effects associated with Alpracon are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

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Free neutrophil elastase (NE), neutrophil elastase/alpha(1)-anti-trypsin complex (NE-AAT), tumour necrosis factor receptor (p55) and interleukin-8 (IL-8) were measured in cell free supernatants. Blood flow causes induced voltages via the magnetohydrodynamic (MHD) effect distorting electrograms (EGMs) made during magnetic resonance imaging. A case-control study in 100 patients with symptomatic PAD and 100 control subjects matched for age, sex, and diabetes mellitus was conducted. Data: archival information on the physical stature and weight of American men during World War I and World War II. The exposure was the use of the price transparency platform to search for laboratory tests, advanced imaging services, or clinician office visits before receiving care for that service. Outcomes included times from transplantation to graft failure (including patient death), return to dialysis or pre-emptive re-transplantation, and death with a functioning graft. Potentially life-saving role for temporary endovascular balloon occlusion in atypical mediastinal hematoma. The limb bud organ culture system offers a variety of endpoints which may be monitored in the screening process. To describe the distribution and evolution over time of bone marrow oedema (BME) on magnetic resonance imaging of the sacroiliac joint (MRI-SIJ) in patients with recent-onset inflammatory back pain (IBP) suspected for axial spondyloarthritis (axSpA). A genetic correlation between Brugada syndrome (BS) and sinus node dysfunction (SND) has been proposed, although the clinical and electrophysiologic characteristics of this concomitant condition are unknown.

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This activity increased the focus on antimicrobial resistance issues and on laboratory quality assurance issues. Thus, we performed molecular dynamics simulations in this study to elucidate the detailed penetration process and mechanism. Age-related dynamics of natural killer activity and basic lymphocyte populations in the peripheral blood of healthy women. 3) Differences in IL28Brs12979860 genotypes could be a consequence of environmental or ethnic variation. Blood measurements of BNP and NT-proBNP have been used to identify patients with heart failure (HF). We demonstrate that the antioxidative effect of green tea decreases the formation of calcium oxalate stones, OPN (osteopontin) expression, and apoptosis, and increases SOD (superoxide dismutase) activity in rat kidney tissues. Internet use among people living with HIV/AIDS: coping and health-related correlates. Assembly of NF-L subunits into filaments does not require nucleotide binding or hydrolysis but is strongly dependent on ionic strength, pH, and temperature.

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Increase of erroneous action quantity is caused probably by a series of physiological, psychophysiological and psychological changes in the condition of a man under the action of alcohol. Few myopic traction maculopathy cases have been studied with SDOCT. Multivariate analysis and odds ratios were used to calculate the significance of the variables of interest and to compare the risk of complications attributable to each of the independent variables during each stage of the procedure. Further studies are required to determine how best to overcome these perceived barriers to appropriate anticoagulation. Flexible teaching and learning needs to involve vertical and horizontal integration. Alkaloids as important scaffolds in therapeutic drugs for the treatments of cancer, tuberculosis, and smoking cessation. Fifty-six volunteer medical students participated in three groups balanced for number of subjects, performance at last examination, and hypnotizability. The effects on locomotor activity of mice was assessed in the open field (OF) paradigm, and those on the spatial orientation and learning ability of mice were investigated in the radial arm maze (RAM) paradigm.

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Biologic agents indeed lead to a better prognosis and clinical remission in patients with RA, especially in patients who are not well-controlled with traditional disease-modifying anti-rheumatic drugs (DMARDs). Abdominal BIA is a simple and safe method that is superior to WC for the detection of excessive visceral fat accumulation. Pharmacokinetics and metabolism of oral midazolam in preterm infants. The uniform high mite exposure in summer cottages is likely to imply disease deterioration in patients already allergic to mites. Practical implementation of thermo-tunneling, however, requires the formation of a nanometer-sized gap spanning macroscopically significant surfaces. Because of importance of prognosis, early adaptation of treatment requires an empirical antimicrobial therapy (generally aminopenicillin and macrolide combination). Due to the increasing use of electronic patient records and other health care information technology, we see an increase in requests to utilize these data. The Vojvodina population shows polymorphism of the KIR gene family present in other European and European-derived populations studied previously. We believe that AVSC is an alternative device when specialized jejunal endoscopy is not available. A humanized TLR7/TLR8 transgenic mouse line was engineered for studies using TLR7/8 ligands as vaccine adjuvants.

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Enhanced fluorescence from CdSe/ZnS quantum dot nanophosphors embedded in a one-dimensional photonic crystal backbone structure. Nonlinear waves in networks: model reduction for the sine-Gordon equation. This result indicates for the short aromatic thiol compounds, the AuNPs should enter the cell after the serum-coating regardless of the surface functional groups. The Hospital Anxiety and Depression Scale in Greek cancer patients: psychometric analyses and applicability. Semi-quantitative RT-PCR was used to validate the microarray results. Multiple myeloma: illegitimate switch recombinations and their relation to chromosomal translocations. The earliest recognisable defect is the reduced occupancy by the definitive endoderm in the posterior and lateral region of the prospective mid- and hindgut of the headfold-stage embryo. To isolate and identify the human periodontal ligament stem cells, evaluate osteogenetic capacity, and investigate the changes of osteogenic bone related gene expression in mineralized medium at different times. Despite improvements in surgical techniques and postoperative care, morbidity associated with pancreatoduodenectomy (PD) is still high.

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Cervical cerclage is a surgical intervention involving placing a stitch around the uterine cervix. Our results showed that the bacterial and archaeal community structures in the studied podzols varied with depth and that the bacterial communities in the bleached mottles were significantly different from that in their immediate vicinity. Furthermore, we calculate the primary radiation force acting on a microbubble. These results suggest the possibility that guar induced somatostatin secretion contributes to reduction of postprandial glucose levels at least in NIDDM patients as well as in normal subjects, for somatostatin is reported to inhibit glucose uptake from gastrointestinal tract. If a causal relationship exists, then recurrent laryngeal cancer after irradiation should predominantly be characterized by aneuploidy. Mechanism of drug dissolution rate enhancement from beta-cyclodextrin-drug systems. Linear dynamic features of ambulatory blood pressure in a population-based study. MRI intensity inhomogeneity correction by combining intensity and spatial information. The orl rat is more responsive to methacholine challenge than wild type. Therapeutic options include intercostal tube drainage, video-assisted thoracoscopic surgery (VATS), and medical or surgical pleurodesis.

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CysC is more sensitive than SCr in assessing renal function at the early stage of shock. L-tryptophan treatment in combination with an HFHFD exacerbated hepatic steatosis, expression of HNE-modified proteins, hydroxyproline content, and serum alanine aminotransaminase levels, whereas L-tryptophan alone did not result in these effects. Plasmacytoid dendritic cells in human blood expressed siglec-5 only. Serum levels of both testosterone and luteinizing hormone (LH) were measured by radioimmunoassay (RIA). To better understand whether a single consumer species benefits from diverse resources, we tested how the protective function of a defensive plant resource (i.e. Antipyretic, analgesic and anti-inflammatory activities of ketoprofen beta-cyclodextrin inclusion complexes in animals. Bioluminescence and 19F magnetic resonance imaging visualize the efficacy of lysostaphin alone and in combination with oxacillin against Staphylococcus aureus in murine thigh and catheter-associated infection models.

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Dexmedetomidine produces its neuroprotective effect via the alpha 2A-adrenoceptor subtype. Out of 86 Type 1 and 2 diabetic patients, 49 were untreated, 25 received captopril and 12 received enalapril as chronic treatment. Current tobacco control strategies seek primarily to decrease the demand for cigarettes through measures that encourage individuals to adopt healthier behaviours. Though herbal medicines have been used for cancer prevention and treatment, their scientific evidences still remain unclear so far. A contributory role for ACTH in promoting inhibition is not ruled out, but neither is it likely that elevated ACTH alone accounts for the observed reproductive inhibition in animals taken from populations. Data on sick leave and unemployment before injury were gathered from the Swedish social insurance agency. Attenuation of IGF-I receptor signaling inhibits serum-induced proliferation of prostate cancer cells. The gap between the axolemma of the nerve terminals and immunocytes was 20-200 nm.

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The major compound emitted from the mites is (4R,6R,8R)-4,6,8-trimethyldecan-2-one (4R,6R,8R-8). Here we showed that clk/STY, as well as other members of the family (e.g. pylori virulence factors and gastric disorders were recommended. Due to the influence of personality traits on behavior in general, the secondary aim of our study was to investigate the possible impact of personality disorders on dental status. Western blotting indicated the upregulation of p53 and Bax proteins, whereas Bcl-2 was significantly downregulated. The preoperative and postoperative photographs of 52 patients were reviewed retrospectively.

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In young rats, BDNF-LTP was accompanied by increased activation of the BDNF receptor TrkB, and extracellular signal-regulated kinase (ERK), as well as enhanced evoked release of glutamate in synaptosomes prepared from DG. Although all factors evidenced support for parenting interventions, subtle differences emerged between factors regarding the endorsed content, barriers and delivery of interventions. The molecular mechanisms involved in this mTOR-mediated hypoxia-induced chemoresistance, however, are unclear. Behavior planning is presented as a model of language evolution from storytelling. During 41 d of observation postchallenge there was low or no mortality in all groups, and no virus was detected in the small number of fish that died. Antibody reactivity to leukotoxin antigens which were significantly correlated with resistance and common with important surface antigens were detected at 86, 66, and 49 kDa. As predicted, reductions in the LPP following reappraisal were greater for older children and those showing less anxiety. This raises the question as to the nature of the bonds that hold two molecules of sTfR together to form a dimer. After review, each anesthesiologist assigned a Likert score based on his or her perception of risk for oversedation-related sequelae in each record.

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Sexually dimorphic effect of in vitro fertilization (IVF) on adult mouse fat and liver metabolomes. Cognition can be defined as all mental activities that are involved in acquisition, processing, storage and retrieval of information. Intravenous steroid administration on the day of tonsillectomy in children was an independent risk factor for severe bleeding requiring reoperation. Although evidence from animals and humans consistently supports the therapeutic effect of these phytomedicines, multicenter large-scale clinical trials have not been conducted to evaluate the safety and efficacy of these herbal medicines and their interaction with conventional drugs when administered simultaneously. The underlying factorial structure of PACIC, which reflects the patient perspective, is dynamic, patient-centered, and differs from the original 5-factor model that was more aligned with views of healthcare delivery stakeholders.

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Sociodemographic and clinical characteristics, as well as type of diet, were explored as potential predictive factors. Echinoderms are well known as being able to regenerate body parts and thus provide excellent models for studying regenerative processes in adult organisms. The homogeneous studies were analyzed and compared using Revman 5.2.6 software, and then effect model was selected and analyzed. Treatment of chronic hepatitis C in patients not responding to interferon. With the advent of detailed knowledge of mechanisms of gene expression, this definition was superseded by another: epigenetics concerned the transmission of phenotype through mitosis or the germ line by mechanisms that did not involve changes in the DNA sequence. Infusion of insulin (0.2 U/kg per h, i.v.) caused a significant drop in T(b). The extracted compounds were derivatized with trifluoroacetic anhydride and analyzed by selected ion monitoring. In several retrospective studies, survival rates were at least similar with intensity-modulated radiotherapy as those reported with three-dimensional irradiation. The germinal matrix neuroepithelium and the choroidal fissure of the fetal choroid plexus commonly possess microvessels that are often poorly developed. Ketone body-induced intracellular metabolomic reprogramming in pancreatic cancer cells also leads to a significantly diminished cachexia in cell line models.

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Often, misdiagnosis during the acute stages of CF leads to irreversible and persistent joint destruction which may be refractory to medical or surgical treatment. Altogether, our data point toward a role for NADPH oxidases in signalling fungal developmental transitions with respect to nutrient availability. The structure and implementation of the two proposed individual-based arava drug bacterial models are discussed, and some results from simulation experiments are presented, illustrating their adaptive properties. Other events such as the postpartum negative energy balance also have similar multilevel effects on postpartum endocrinology. Do nonsteroidal anti-inflammatory drugs affect the risk of developing ovarian cancer?. In response to cytokine stimuli, Stats are phosphorylated and translocated to the nucleus to activate target genes. The apex site in the parent Au5(-) cluster is not always the most preferred site for the chemisorption, and two bridged adsorption CO molecules are observed in the lowest-energy (CO)3Au5(-) cluster.

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In the 16 patients who did not take sulfonylurea, fasting plasma glucose (FPG) decreased and HbA1c significantly decreased from 3 months to 6 months. Incubation of purified bovine aortic lysyl oxidase with rat liver or calf thymus H1 histone results in the catalytic formation of hydrogen peroxide, indicating the substrate potential of H1 for this connective tissue enzyme. Prospective clinical trials have shown that antihypertensive classes differ in their ability to control excessive BP fluctuations with an impact in clinical outcomes. Further studies with this type of preplanning equipment may show a decrease in operative time and morbidity, decrease in radiation exposure, and improvement in accuracy of plate and screw placement. Thus, we have investigated EGFRvIII as a potential modulator of cellular radiation responses and explored the feasibility of adenovirus (Ad)-mediated expression of dominant-negative EGFR-CD533 as a gene therapeutic approach for inhibiting EGFRvIII function in vitro max dose of bystolic daily and in vivo. To make robust inferences on the role of different stages of HIV infection in the sexual spread of HIV, models should take into account that transmission rates may be asymmetric by sex.

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Congenital disorders of bilirubin metabolism of the type of Meulengracht-Gilbert intermittent juvenile icterus. Desorption electrospray ionization imaging of small organics on mineral surfaces. We show that when DCA and metformin are used in combination, synergistic induction of apoptosis of breast cancer cells occurs. Green tea extract is an inexpensive, nontoxic, and effective treatment modality in individuals with a risk for acute kidney injury of contrast media. Since then, many thoracic surgery departments have progressively adopted this technique, although the approach description may vary greatly among them. The lactose intolerance quick test (LIQT) measures lactase activity in duodenal biopsies and may be performed as part of upper gastrointestinal endoscopy. Neurosurgeons have observed the unexpected irregular shape and size of the aneurysmal dome and neck in many cases of unruptured cerebral aneurysms during aneurysmal microsurgery, and known the discrepancy between the findings of angiography and operative view. Medicaid expansion may not result in improved dental use among Medicaid patients unless dental services are covered and dental practitioners appropriately engaged.

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Water hyacinth plants were grown on nutrient solutions with five different lead concentrations: 0.00, 0.50, 1.00, 2.00 and 4.00 mg L-1 by 20 days. These have opened the way towards understanding why sex ratios become male biased and allow a proper assessment of its consequences in the epidemiology, diagnosis and pathology of infection. Formation of one procentriole next to each pre-existing centriole is essential for centrosome duplication, robust bipolar spindle assembly and maintenance of genome integrity. Cases of successful lioresal tablet 20mg desensitization against PAS using orally administered ascending doses are described in the literature. However, under pathological conditions after severe tissue injury and in inflammatory or neuropathic diseases, this system can become sensitized, and pain can then turn into a disease.

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