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Alpradol (Alprazolam)

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Alprazolam, available under the trade name Xanax, is a potent, short-acting benzodiazepine anxiolytic—a minor tranquilizer. It is commonly used for the treatment of anxiety disorders, especially of panic disorder, but also in the treatment of generalized anxiety disorder (GAD) or social anxiety disorder. It was the 12th most prescribed medicine in the United States in 2010. Alpradol, like other benzodiazepines, binds to specific sites on the GABAA receptor. It possesses anxiolytic, sedative, hypnotic, skeletal muscle relaxant, anticonvulsant, amnestic, and antidepressant properties. Alpradol is available for oral administration as compressed tablets (CT) and extended-release capsules (XR).

Other names for this medication:
Actirax, Alflux, Allam, Alpraday, Alprax, Alzep, Alzin, Alzocum, Alzokam, Alzonex, Alzopam, Alzoset, Alzot, Anzal, Apsolam, Ateez, Azolam, Azoslip, Calmtec, Dazolam, Depoxit, Depsolam, Elzopam, Emlol, Endep, Erazol, Fultop, Luzarn, Mebaspa, Meloprax, Onapract, Ozolam, Pronil, Resolin, Samrox, Serxanti, Sinaday, Suzilam, Tenrid, Tenschem, Tensyl, Texidep, Trazopin, Zamitol, Zopain, Zopax, Zotin

Similar Products:
Fasigyn, Lexapro, Minipress, Actos, Coumadin, Altace, Zovirax, Decadron, Prandin, Nexium

Also known as: Alprazolam


Alprazolam is used to relieve symptoms of anxiety, including anxiety caused by depression. It is also used to treat panic disorder in some patients.

Alprazolam is a benzodiazepine. Benzodiazepines belong to the group of medicines called central nervous system (CNS) depressants, which are medicines that slow down the nervous system.

This medicine is available only with your doctor's prescription.


Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results.

Do not crush, chew, or break an extended-release tablet. Swallow the pill whole. It is specially made to release medicine slowly in the body. Breaking the pill would cause too much of the drug to be released at one time.

Measure the liquid form of Alpradol with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

Do not swallow the orally disintegrating tablets whole. Allow it to dissolve in your mouth without chewing.

Contact your doctor if this medicine seems to stop working as well in treating your panic or anxiety symptoms.

You may have seizures or withdrawal symptoms when you stop using Alpradol. Ask your doctor how to avoid withdrawal symptoms when you stop using Alpradol.

Keep track of the amount of medicine used from each new bottle. Alpradol is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of alprazolam can be fatal.

Overdose symptoms may include extreme drowsiness, confusion, muscle weakness, loss of balance or coordination, feeling light-headed, and fainting.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

It is very important to protect the orally disintegrating tablets from moisture. Remove and throw away any cotton packaging from the medicine bottle when you first use the medicine.

Detailed Alpradol dosage information

Side effects

The most common side effects associated with Alpradol are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not use Alpradol if you are pregnant. It could harm the unborn baby.

Do not use this medication if you are allergic to Alpradol or to other benzodiazepines, such as chlordiazepoxide (Librium), clorazepate (Tranxene), diazepam (Valium), lorazepam (Ativan), or oxazepam (Serax).

Before you take Alpradol, tell your doctor if you have asthma or other breathing problems, glaucoma, kidney or liver disease, a history of alcoholism, or a history of depression, suicidal thoughts, or addiction to drugs or alcohol.

Do not drink alcohol while taking Alpradol. This medication can increase the effects of alcohol.

Alpradol may be habit-forming and should be used only by the person for whom it was prescribed. Keep the medication in a secure place where others cannot get to it.

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This contribution reviews studies of major gene effects in inbred strains of mice with high aggressivity, and considers the relevance of some rare single-gene disorders in man which include uncontrollably aggressive behavior as part of the phenotype. Extrathoracic extramedullary hematopoiesis is a rare and usually asymptomatic condition. Patients admitted to a hospital emergency asthma service had nasal aspirates (NAs) taken and peak expiratory flow (PEF) measured on admission and again 7, 28 and 56 days after admission. The onset in elderly subjects of clinical signs of chronic venous insufficiency (CVI), without a previous history of venous disease of the lower limbs, raises questions about the etiology. Molecular dosimetry studies of forward mutation induced at the yg2 locus in maize by ethyl methanesulfonate. Different procedures of managing difficult shoulder delivery are described. Nasal fibroblasts produced high levels of VEGF, when cultured under hypoxic condition and this production was remarkably enhanced in the presence of TNF-alpha or endotoxin.

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These include the effects of binding cavity size and hydrophobic and electrostatic interaction on the reversal activities of these compounds. Each participant completed the SDMT and Stroop Interference Test at baseline and after random allocation to a condition (HIIP vs control). Under optimum conditions all the species of bacteria tested were capable of splitting sulphasalazine and there were no major differences in the degree of activity shown by different species. Time-patterned treatments of cancer involve two distinct lines of research. It should be noted that anterior instability has been described after patellectomy and could be attributed to complete absence of the patella, which is rare in NPS. To explore the complex allele distribution of the D1S80 polymorphic locus in different populations comparing the derived single nucleotide polymorphism (SNP) rs16824398-D1S80 haplotype frequencies in samples of European (Russians), Asian (Yakuts) and sub-Saharan African origin. Daring as this hypothesis is, I argue that it is not possible to know this to be the case and that it is premised on epistemological individualism, a thesis itself replete with problems.

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Noradrenergic modulation of the limbic system by way of the locus coeruleus accounts for a number of clinical observations, such as the worsening of tardive dyskinesia by stress, the greater risk for tardive dyskinesia in patients with affective disorder, the time-of-onset of tardive dyskinesia, and the coexistence of tardive dyskinesia and pseudoparkinsonism. Cyclic AMP-dependent kinase regulates Raf-1 kinase mainly by phosphorylation of serine 259. Circulating levels of all-trans retinol (Vitamin A) were not different between the two groups. Initial evidence of subjective improvement in the treatment group compared to the placebo group was not sustained with sensitivity analysis. Negative correlation of the expression level of proteins with respective molecular weights supports the notion that P. SYBR Green I-based product-enhanced reverse transcriptase assay for quantification of retroviral PFV and detection of the divalent cation preference of PFV RT. GST Y-1 showed specific activity 10.4-times and 6.0-times higher when 1-chloro-2,4-dinitrobenzene and o-dinitrobenzene were used as substrates, respectively, than GST Y-2. This article reviews the latest developments in our understanding of the origin, development, and evolution of nymphalid butterfly eyespots. Participants consisted of 28 Jewish and 14 Arab children (aged 4-18 years) and their parents. Academic medical centers (i.e., teaching hospitals) particularly need an effective strategy that will allow them to meet their tripartite missions of patient care, education, and research in this time of increasing competition and resource constraints.

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Thirty-four patients in a tertiary care neuroscience critical care unit with major traumatic brain injury underwent pH(b) monitoring. Congenital multiple clustered dermatofibroma and multiple eruptive dermatofibromas--unusual presentations of a common entity. Here, we report that deletion of the Hes1 gene in mice promotes acute myeloid leukemia (AML) development induced by the MLL-AF9 fusion protein. Avoidable mortality was analyzed according to the classification used by the Health Department of the Regional Government of Catalonia from 1986-2001 for health areas and causes were grouped as treatable and preventable. Improved FlexX docking using FlexS-determined base fragment placement. The response to systemic treatment in metastatic RCC is also being evaluated in defined subpopulations. Elements in the training are self-experience in small and large groups, supervision and theory discussions. For a 4.5-cm-long coated microfiber, an internal gain of 1.8 dB and a net gain of 0.8 dB for a 1550 nm signal were observed, when combing together the gain of the doped jackets and low loss of microfibers. An evaluation of risk factors for major adverse cardiovascular events during tocilizumab therapy.

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A remarkable increase in hydrodynamic volumes was observed for Co(III) mPEG(20k)-insulin hexamers (1600 kDa), as well as Co(III) mPEG(5k)-insulin hexamers (300 kDa). Earlier detection of HLA alloimmunization in platelet transfusion refractoriness by flow cytometric analysis. Hence, a study was undertaken to investigate the effects of operating temperature (5-41 degrees C) on the morphology and structure of two commercially available thin film composite NF membranes. A similar development was observed in his affected stepbrother and one first-degree cousin. Central Asian republics: a case study for medical education reform. Further, recognition of facial expressions of anger, sadness and disgust is impaired in ALS, even when cognition is preserved. Numerous studies were carried out on heroin to investigate its rate of hydrolysis. Health status and biological maturity of children in the Udmurtsk Autonomic Republic starting school at age 6. We describe coronary artery spasm occurring in the immediate postoperative period following coronary artery bypass operation. Detection and assessment of risk factors associated with natural concurrent infection of Trypanosoma evansi and Anaplasma marginale in dairy animals by duplex PCR in eastern Punjab.

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A convenient method for preparation of high-purity, Amadori-glycated phosphatidylethanolamine and its prooxidant effect. The increased metabolism was associated with increased activities of hepatic phenylalanine:pyruvate aminotransferase, tyrosine aminotransferase and phenylalanine hydroxylase. We first examined the influence of insulin on the proliferation of several human cell lines. Selective localization of glutaminase in spinal and sensory nerve cells. Drosophila Orc6 protein, the smallest subunit of the origin recognition complex (ORC), directly binds to septin complex and facilitates septin filament formation. Washing out DMSO in thawed HPC-A by use of this approach is safe and efficient in terms of recovery and viability of nucleated and progenitor cells. We report a Japanese male patient with molecularly confirmed Kabuki syndrome who was found to have CPHD. Prospective cohort study of pregnancy outcome in relation to gestational age at primary maternal CMV infection.

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EA also promoted cell cycle arrest substantially at G2/M phase in HCT-15 cells. Characterization and antioxidant activities of the polysaccharides from Radix Cyathulae officinalis Kuan. Patients previously treated with ketoconazole were excluded from phase III trials of abiraterone acetate due to potential overlapping mechanism of action. Eviction of the stalled helicase allows leading strands to be extended toward the ICL, followed by endonucleolytic processing of the crosslink, lesion bypass, and DSB repair. Increased efficacy may be achieved by performing multiple passes at the time of treatment.

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As the severity of injury escalates, the surgical difficulties increase, making acceptable results of therapy difficult to achieve. Impact of worker education on respiratory symptoms and sensitization in bakeries. A 49-year-old female patient admitted to our hospital with the complaint of occasional abdominal pain. A polymorphism in the promoter region of the survivin gene is related to hemorrhagic transformation in patients with acute ischemic stroke. Cultured NCB-20 mouse neuroblastoma X Chinese hamster brain clonal hybrid cells express an adenylate cyclase-coupled receptor for serotonin (5HT) which corresponds pharmacologically to the 5HT1 receptor in whole brain, except for its much lower affinity for serotonin. Development of NADPH diaphorase-positive pedunculopontine nucleus neurons.

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We analyze second-harmonic generation (SHG) at a thin effectively quadratic nonlinear interface between two linear optical media. The Cross-Cultural Loss Scale: development and psychometric evaluation. This result would explain why most archaea and bacteria do not normally use U or a modified U in the anticodon wobble position of isoleucine tRNA for reading the codon AUA. Results support the utility of this animal model to elucidate serotonergic changes linking dieting to binge eating. Data are lacking on the association between preoperative FABP serum level and postoperative incidence of AKI. Although the endoscopic finding was partially improved, clinical symptoms and histologic finding were persisted. Follow-up of the schizophrenic patient by the general practitioner. Limited tissue for analysis remained in the clinical sample tissue blocks. Study of the contractile and electrophysiological maturation responses of the human foetal myocardium. Dissecting individual cellular pathways to reveal the function of numerous proteins is an approach to drug discovery.

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Three hundred and ninety-seven grandmultiparous women were compared with three hundred and ninety-seven age-matched multiparous women. Our methodology included a microcosting and time study focusing on estimating average direct and indirect costs. A new approach to monitoring tumor clone dynamics (Carreira et al., this issue) uses sequential biopsies and circulating DNA to help optimize treatment in metastatic prostate cancer. The emphasis was to study the number of positive nodes found after axillary lymph node dissection (ALND) following a positive ultrasound-guided biopsy or a positive sentinel lymph node biopsy (SLNB). Propionibacterium acnes is a normal inhabitant of the skin and mucosal surfaces and is rarely identified as a cause of significant infection. Performance and electron transport properties of TiO(2) nanocomposite dye-sensitized solar cells. Images of patients, x-rays, study models, and general views of the practice and staff were often left to the more experienced photographer. Pharmacological investigation of rotational behaviors produced by unilateral electrical stimulation of the substantia nigra in the rat. These bacteria possess major and minor resistance mechanisms that will be described in detail. Effect of glass plavix 75 mg nedir dissolution products on the detection of proteins by silver staining.

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The present report describes a 70 year old female patient who was complicated by catheter-related extensive coronary dissection in the right coronary artery (RCA) when treated for an acute myocardial infarction. A total of 127 consecutive patients with functional constipation were examined in the left-lateral position with rectal palpation and rectoscopy according to a protocol. Hygiene training of food handlers in hospital settings: important factor in the prevention of nosocomial infections. Moreover, recent data implicate SIRT3 and SIRT6 in controlling mitochondrial and nuclear circadian functions, revealing previously unappreciated roles that extend to various subcellular domains, including fatty acid metabolism in the mitochondria. To compare ECG-gated and non-gated CT angiography of the aorta at the same radiation dose, with regard to motion artifacts (MA), diagnostic confidence (DC) and signal-to-noise-ratios (SNRs). Linear free-energy analysis of mercury(II) and cadmium(II) binding to three-stranded coiled coils. Collaborative study of the determination of the dithiocarbamate residues by a modified carbon disulfide evolution method.

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alpha-Adrenoceptor subtypes were demonstrated in an in vitro preparation phenergan dose children of the vascular smooth muscle of the canine nasal mucosa. Compared with peritumor tissues, tumor tissues showed decreased SDF-1 expression levels according to TNM stage progression in gastric cancer specimens. The latter are thought to be FGF8 and BMP4, proteins secreted from the neural plate to induce lens formation in the overlying ectoderm. We report a patient with progressive brainstem infarction despite medical therapy. Hierarchical structures of nickel sulfide have been grown by the hydrothermal method.

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Loss of heterozygosity and point mutation at Aprt locus in T cells and fibroblasts of Pms2-/- mice. We investigated the impact of emotional task-irrelevant visual stimuli on cortical activation during verbal WM. This suggests that the pathways of the cold and pressure unfolding are substantially different from that of the heat unfolding. It was shown that the effects of the analgesics of a different structure: phenylpiperidine derivatives (trimeperidine, fentanyl), diphenylacetic acid derivative (dimenoxadol) and 3-benzazocine tricyclic derivative (pentazocine) were unchanged by the studied GABA-ergic analyzers. A recently presented meta-analysis of the available RCTs has confirmed the efficacy of prophylactic CSFs. Sequences were aligned, and the results obtained showed that the products of PCR amplification were the required specific gene fragments of HBV, and HDV.

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The Chanock lecture, instituted in 2003 to acknowledge important contributors to RSV research, was presented by Peter Collins. We expressed and purified the N-terminal fragment of ClpB (residues 1-147). typhimurium mutants were avirulent in mice, an indication that these proteins are required for Salmonella virulence. A brief review of some of the mechanisms by which activation of the renin-angiotensin system can inflict damage on the heart is presented. A highly facile coinclusion method has been used for making doxorubicin and folic acid loaded vesicles. SLE preterm offspring seem to be more prone to neonatal infection, small for gestational age and at a higher risk of congenital heart disease as compared to preterm babies from women without SLE. Simultaneously, a satisfactory model for the cellular mechanisms that regulate normal sperm function must be established. Raman spectra of ionic liquids: a simulation study of LaCl3 and its mixtures with alkali chlorides.

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tuberculosis, the disclosure of the GgH function allows reconfiguration of the MGLP pathway in rapidly-growing species and accommodation of this possible regulatory step. Potential-dependent changes in the conductance of the somas of snail neurons induced by glutamate in near-threshold concentrations. Enhanced expression of EsWAX1 improves drought tolerance with increased accumulation of cuticular wax and ascorbic acid in transgenic Arabidopsis. In white, singleton children in the United Kingdom, breastfeeding is associated with improved cognitive development, particularly in children born preterm. Studies on the morphological structure of the liver in patients with gasric and duodenal ulcers. Astaxanthin inhibits apoptosis in alveolar epithelial cells type II in vivo and in vitro through the ROS-dependent mitochondrial signalling pathway. Interestingly, physical mixture of levofloxacin and indolicidin showed improvement in the activity against Gram-positive bacteria. Gestational diabetes mellitus (GDM), preterm delivery, caesarean section, fetal growth restriction (FGR) and small-for-gestational age (SGA), anthropometric birth outcomes including weight, length and head circumference (HC).

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Clostridium sordellii toxic shock syndrome after medical abortion with mifepristone and intravaginal misoprostol--United States and Canada, 2001-2005. We use molecular-dynamics simulations to study the effect of temperature and pressure on the local structure of liquid water in parallel with neutron-scattering experiments. EULAR recommendations for vaccination in paediatric patients with rheumatic diseases. We report that combined treatment with Scl-Ab and iPTH was more potent than either iPTH or Scl-Ab alone in increasing stromal cell production of OPG, osteoblastogenesis, osteoblast life span, bone turnover, bone mineral density, and trabecular bone volume and structure in mice with T cells capable of producing Wnt10b. Improved ultram name brand compliance with clinical practice guidelines was seen in both models. Rac regulation of chemotaxis and morphogenesis in Dictyostelium. Anticoagulants and antiplatelets may be safely continued perioperatively to avoid complications secondary to their systemic disease. On the contrary the continuous reduction in the number of young cysts clearly shows a slow but constant decrease of the infection rate. Treatment of traditional Chinese medicine for idiopathic male infertility. It has been discussed that the nonsynaptic release sites in the CNS of the snail Lymnaea stagnalis, and the nonsynaptic varicosities in the rat brain are the morphological correlates of nonsynaptic communication in the CNS.

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No patients needed plate removal because of irritation of the tendons. In the present study, the question whether jervine acts directly or indirectly noroxin medicine on mammalian embryos to produce malformations and the nature of the target tissue or cells were examined using whole-embryo cultures of the CD rat. In addition, androgen-enhanced cell growth was inhibited by antiandrogen, but not by antiestrogen, while estrogen-stimulated cell growth was suppressed by antiestrogen. Advances in operative techniques and perioperative management have improved the outcome of restorative proctocolectomies. This review highlights the relationship among individual constituents and the anti-inflammatory activity of Hp extracts and proposes that interactions of constituents may be important for the anti-inflammatory activity of botanical extracts, although the exact mechanisms of the interactions are still unclear. We next examined the role of cytoskeleton in the AQP2 trafficking and localization. CASA experiment: slides were evaluated using the Integrated Visual Optical System and compared to technician results. MD improves the muscular mass without increasing the total body weight, so this data could be determinant to define profiles for athletes.

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Few differences were noted between the activity groups and the controls on the posttest with pretest scores controlled. Response to corticosteroids and cytotoxic drugs in a case of idiopathic hypereosinophilic syndrome with predominantly elevated eosinophils and multiple clinical manifestations. We assessed proliferation, apoptosis and senescence in cultured cells, and tumour formation in mice. The Staphylococcus aureus CsoR regulates both chromosomal and plasmid-encoded copper resistance mechanisms. The purpose was to determine whether or not a novel device used in conjunction with orthodontic treatment produced root resorption shown on 3D images generated from a new cone beam computerized tomography. Antiretroviral therapy (ART) is associated with a myriad of metabolic complications which are potential cardiovascular risk factors. To investigate the effects of curcumin, an antioxidant and anti-inflammatory agent, on free oxygen radicals and lipid peroxidation in an experimental sepsis model, as well as to determine the role of curcumin in preventing hepatorenal tissue damage caused by sepsis. It will be imperative to ensure that comprehensive and specialized training sites are available to train researchers to support the regulation of therapeutic products.

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We evaluated whether count subtraction eliminated the need for higher activity doses in the second part of the 1-d stress-rest myocardial perfusion imaging (MPI) protocol. Pharmacological and biochemical evidence has implied that a widespread opioid peptide system exists within the cerebral cortex to mediate a variety of opiate effects. Estrogens shape brain circuits during development, and the capacity to synthesize estrogens locally has consequences for both sexual differentiation and the acute modulation of circuits during early learning. We have purified glutamine synthetase over 130-fold from Saccharomyces cerevisiae. Increasing the number of biopsy cores improves the concordance of biopsy Gleason score to prostatectomy Gleason score. Upper abdominal symptoms, as well as symptoms suggesting rhinitis, were well correlated with asthma symptoms. Traditional methods of collaboration yielded mixed results, making obvious a need for dedicated collaboration funds and a better framework to identify and align high-yield opportunities.

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