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Alprastan (Alprazolam)

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Alprazolam, available under the trade name Xanax, is a potent, short-acting benzodiazepine anxiolytic—a minor tranquilizer. It is commonly used for the treatment of anxiety disorders, especially of panic disorder, but also in the treatment of generalized anxiety disorder (GAD) or social anxiety disorder. It was the 12th most prescribed medicine in the United States in 2010. Alprastan, like other benzodiazepines, binds to specific sites on the GABAA receptor. It possesses anxiolytic, sedative, hypnotic, skeletal muscle relaxant, anticonvulsant, amnestic, and antidepressant properties. Alprastan is available for oral administration as compressed tablets (CT) and extended-release capsules (XR).

Other names for this medication:
Aleez, Alpanol, Alpraday, Alpradol, Alprastan, Alprop, Alprose, Altrex, Alzep, Alzocum, Alzomax, Anilam, Anlzium, Anxitab, Avizolem, Depoxit, Depsolam, Depten, Elflu, Endep, Flunix, Fluprax, Kurelam, Luzarn, Mebasap, Morecalm, Nokzok, Pifzot, Pranol, Prazil, Rescalm, Restam, Sanprazole, Tenolam, Trika, Zocam, Zolent

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Ticlid, Lioresal, Reminyl, Asacol, Requip, Amaryl, Xalatan, Nuvigil, Imuran, Motrin

Also known as: Alprazolam


{name} (alprazolam) is a benzodiazepine (ben-zoe-dye-AZE-eh-peen). It is thought that alprazolam works by enhancing the activity of certain neurotransmitters in the brain.

{name} is used to treat anxiety disorders and anxiety caused by depression.

{name} is also used to treat panic disorders with or without a fear of places and situations that might cause panic, helplessness, or embarrassment (agoraphobia).

It is dangerous to purchase {name} on the Internet or outside the United States. The sale and distribution of medicines outside the U.S. does not comply with safe-use regulations of the Food and Drug Administration (FDA). These medications may contain dangerous ingredients, or may not be distributed by a licensed pharmacy.


Take Alprastan exactly as prescribed by your doctor. Follow all directions on your prescription label. Never use Alprastan in larger amounts, or for longer than prescribed. Tell your doctor if the medicine seems to stop working as well in treating your symptoms.

Alprastan may be habit-forming. Never share Alprastan with another person, especially someone with a history of drug abuse or addiction. Keep the medication in a place where others cannot get to it.

Misuse of habit-forming medicine can cause addiction, overdose, or death. Selling or giving away this medicine is against the law.

Do not crush, chew, or break a Alprastan extended-release tablet. Swallow the tablet whole. Call your doctor if this medicine seems to stop working as well in treating your panic or anxiety symptoms. Do not stop using Alprastan suddenly, or you could have unpleasant withdrawal symptoms. Ask your doctor how to safely stop using this medicine.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of alprazolam can be fatal.

Overdose symptoms may include extreme drowsiness, confusion, muscle weakness, loss of balance or coordination, feeling light-headed, and fainting.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

It is very important to protect the orally disintegrating tablets from moisture. Remove and throw away any cotton packaging from the medicine bottle when you first use the medicine.

Detailed Alprastan XR dosage information

Side effects

The most common side effects associated with Alprastan are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Studies in women breastfeeding have demonstrated harmful infant effects. An alternative to this medication should be prescribed or you should stop breastfeeding while using this medicine.

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At last follow-up, the mean absolute Constant score was 37 points: pain 10 pts, activity 9 pts, motion 14 pts, force 4 pts. Effect of different analgesics on pain relief during extracorporeal shock wave lithotripsy. To assess the safety and efficacy of sofosbuvir plus ledipasvir in patients with chronic HCV GT-1 that relapsed after sofosbuvir plus ribavirin therapy. Symptoms and Quality of Life: Before and after stem cell transplantation in cancer. The homozygous Ala280Val variation in the third intracellular loop of the histamine H(3) receptor of a patient with Shy-Drager syndrome may be related to the etiology of the illness due to altered norepinephrine release.

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SC-19220, a PG receptors antagonist, also inhibited the contraction and ACh release induced by nicotine. Mutations in the PCCA or PCCB genes, encoding both subunits of propionyl-CoA carboxylase, result in propionic acidemia, a life-threatening inborn error of metabolism with autosomal recessive inheritance. The effect of nebulized beta-stimulant on the regional ventilation-perfusion ratio and blood gas analysis. Multiple protein-DNA interactions within the human interferon-beta regulatory element. We study the electrically driven spreading of dielectric liquid films in wedge-shaped gaps across which a potential difference is applied. Spirituality may be helpful to cope with these negative emotions. Residual subretinal fluid may be identified intraoperatively despite tamponade with perfluoro-n-octane. The need to provide rigid bony fixation in the surgical treatment of craniofacial deformities has inspired an on-going evolution of surgical innovations and implants.

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In the recent decade, high-throughput genotyping and next-generation sequencing platforms have enabled genome-wide association studies (GWAS) of many complex human diseases. The relation between prefrontal cortex structure and tic inhibition has not been investigated. Towards a population genetics of microorganisms: The clonal theory of parasitic protozoa. Data were analyzed using descriptive and nonparametric statistics, excluding the three unknown students. A logistic approach to manufacture erythrocytes ex-vivo by using modern tissue culture techniques have surfaced in the past few years. An efficient moving target detection algorithm based on sparsity-aware spectrum estimation. Effective communication with the mentally challenged person during treatment of minor ailments. Multi-scale modeling of mycosubtilin lipopeptides at the air/water interface: structure and optical second harmonic generation. Prevention of gastroduodenal content reflux and delayed gastric emptying after esophagectomy: gastric tube reconstruction with duodenal diversion plus Roux-en-Y anastomosis. We validate the MBWSS using a publicly available dataset, a paediatric cohort, an adolescent cohort, intra-surgical scans and demonstrate flexibility of the approach by modifying the method to extract macaque brains.


Bronchoalveolar lavage fluid and serum canine surfactant protein A concentrations in dogs with chronic cough by bronchial and interstitial lung diseases. The transdermal delivery of ENX to the breast should be further developed in preclinical and clinical studies. In addition, there is some but limited evidence that RSV variation may be, at least partially, immune (antibody) driven. The latter interpretation was strengthened by the observation that AC injection of a mixture of gC- (expressing normal gB) and gB- (expressing normal gC) effectively suppressed the DTH response to wild-type HSV-1. With the agreement of all affected parties, students experience some simulated events of the type that they may experience while on call as foundation-year doctors. To evaluate the results of an integrated maternal, newborn, and child health (MNCH) program to improve maternal health outcomes in Northern Nigeria. Traumatic optic neuropathy is a cause of loss of vision associated with head injuries. The redox potentials, formal heterogeneous electron-transfer rates, and thermal denaturation temperatures of the two reconstituted Mbs were also indistinguishable.

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Twenty-three clinically and histopathologically proven WG (16 CWG, 7 LWG) were studied. Borrelia burgdorferi sensu lato is a tick-borne pathogen that causes Lyme disease. This detailed review, which summarizes studies on the major anti-oxidant enzymes of helminths, clearly illustrates that methods to block or overcome anti-oxidant protection may be a fertile field in the search for improved ways to inhibit parasite survival. To the best of our knowledge, this is the second reported case of an sex cord-stromal tumors recurring in small bowel mucosa and mimicking a primary colorectal tumor. RAMONA: a Web application for gene set analysis on multilevel omics data. In the other reported NRAS-/BAP1-mutated MBAIT case, presence of a BAP1 germline mutation was not tested. A marked lower level of formic acid, as well as higher levels of acetic acid, propionic acid and butyric acid in gingival crevicular fluid of patients with G-AgP was consistent with periodontal pathogen infection.

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249 pregnant women who had received the diagnosis of a severe lethal fetal malformation. Comprehensive detection and identification of human coronaviruses, including the SARS-associated coronavirus, with a single RT-PCR assay. To determine the risk of clinical trial failure for drugs developed for type-2 diabetes. We describe a sensitive and specific liquid-chromatographic assay for pentoxifylline and three of its metabolites in human plasma and urine. Further, we believe that imaging-guided lifestyle management may have considerable potential for improving outcomes and reducing health-care costs by eliminating unnecessary invasive procedures. We aimed to quantify the proportion of the general population with OLD, and the intersections of physician-diagnosed asthma, chronic bronchitis (CB), and emphysema in two Italian general population samples, in relationship to airflow obstruction (AO) determined through spirometry.

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Functional genetic analysis of the GarML gene cluster in Lactococcus garvieae DCC43 gives new insights into circular bacteriocin biosynthesis. Gene expression profile of steroid-induced necrosis of femoral head of rats. Pneumothorax is a life threatening situation that requires fast treatment. The release of Cu in soil pore waters and redistribution in the solid phase towards more labile pools were strongly dependent on the alternation between oxidizing and reducing conditions. A modification of the washing technique for quantitative evaluation of the ectoparasite load of small mammals. Because of the lower sensitivity of beta-receptors in old persons, the higher plasma concentrations of beta-receptor blockers in this group of patients should not result in a diminished dose of the investigated beta-receptor blockers in the elderly.

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In the model with symmetric hopping rate, a Laplacian term is essentially absent from the continuum equation. Phthalate esters are ubiquitous environmental contaminants and numerous organisms are thus exposed to various levels of phthalates in their natural habitat. Strong fungal specificity and selectivity for algal symbionts in Florida scrub Cladonia lichens. No overlapping QTLs were identified for the different traits measured in the behavioral tests, supporting the hypothesis that different genetic factors influence social reactivity and tolerance to humans. In CDSM, interactions are represented by ordinary differential equations and compared across conditions through statistical heterogeneity and homogeneity tests. They lack an axoneme or the actin and myosins of other types of motile cells, but their pseudopods contain abundant major sperm protein (MSP), a family of 14-kD polypeptides found exclusively in male gametes. When MEF-wt, MEF-Smad2-/- or MEF-Smad3-/- were co-cultured with KK or exposed to KK/KF co-culture conditioned media, enhanced proliferation and collagen production were seen in MEF-wt and MEF-Smad2-/- but not in MEF-Smad3-/- cells.

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The hepatic xanthine dehydrogenase/oxidase activity was not significantly affected by Mo supplementation. Head injuries are a common occurrence, with continuing care in the years following injury being provided by primary care teams and a variety of speciality services. Starch breakdown was faster in plants of Arabidopsis (Arabidopsis thaliana) ecotype Wassilewskija growing in long days. For example, the model does not support Reelin acting as a repelling or as a stopping signal. Target sugar alcohols and sugars in food samples were extracted in water by ultrasonic method and then reacted with benzoyl chloride to form violet-absorbing products, which were separated on a C18 column with gradient elution using methanol and water as mobile phase. Implications of changes in households and living arrangements for future home-based care needs and costs for disabled elders in China.

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Candidacidal activities of proteins partially purified from rat epidermis. The structure is consistent with a mechanism of in-line displacement via a trigonal bipyramidal transition state. RNase III is a double-stranded RNA-specific endoribonuclease that processes and degrades numerous mRNA molecules in Escherichia coli. The patient received supportive therapy and delivered a healthy child at term. Together with didactics, aligning activities with participant interests, and using existing social structures zithromax 250 mg azithromycin for health message delivery, the approach led to high satisfaction ratings for the three components of SDT along with improved skills, knowledge, and outcomes in cardiovascular fitness. The velocity of the rotation of the mobile ring varied depending on the anisotropy of the shape of the ring. Pulmonary artery systolic pressure and mortality in the oldest old. Approaches to the management of patients with cardiac arrhythmias have significantly evolved over the last decade, with advancement in catheter ablation and device implantation techniques. Outpatients follow up is more intensive in private than in public clinics.

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Measurements were repeated after 1 week and intraclass, intrarater, and interrater correlations of the measurements using the four different methods were analyzed. We found that TNBC cells compared to estrogen receptor (ER) positive cells possess special metabolic characteristics manifested by high glucose uptake, increased lactate production, and low mitochondrial respiration which is correlated with attenuation of mTOR pathway and decreased expression of p70S6K. Proper management of these lesions requires a specific process of evaluation. In man the electroretinogram to pattern reversal stimuli (P-ERG) represents a cone response of the proximal retina, dominated by the cone mechanisms sensitive to red (R) and green (G). Iridium-catalyzed regioselective C-7 amination of indolines has been achieved with organic azides as a facile nitrogen source. Here, we examined differences in the expression of factors related to myogenesis, adipogenesis and skeletal muscle growth during fetal muscle development of lean (Yorkshire) and obese (Chenghua) pig breeds.

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The C4 and Slp genes of the complement region of the murine H-2 major histocompatibility complex. A polymorphism of kynureninase gene in a hypertensive candidate chromosomal region is associated with essential hypertension. Many statistical models have been proposed for survival analysis. This review will discuss the current knowledge relating to the molecular mechanisms involved in the generation of SVs from nerve terminal endosomes, how this relates to other mechanisms of SV production and the functional role of such SVs. The N1(2) is approximately coincident with the N1(1), whereas the P3(2) is coincident with N2(1). Investigations in healthy volunteers and comparison with ranitidine and placebo.

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Physical activity (PA) is a strong and independent CVD risk factor, and despite the fact that current clinical practice guidelines recommend simultaneous treatment of multiple risk factors for optimum management of CKD, PA is rarely addressed by renal care teams. Here, we tested whether incorporating the fiber targets 3PO to CAR, thus recapitulating the Ad5 infection pathway. To identify demographic, morphological and biochemical characteristics of interstitial pregnancies that are associated with a successful outcome of conservative treatment (expectant management or medical treatment with methotrexate). On several occasions we used forearm flap as a free microvascular transplant. Benzodiazepine dose tapering can be done faster in a hospital setting in high-dose abusers, but must be done more slowly in the outpatient setting in therapeutic dosage users. Effects of non-steroid antirheumatic agents on microsomal drug-metabolizing enzymes of rat liver. Blood samples were collected monthly from 10 yearling Jezersko-Solchava, 10 Bovec and 10 Istrian ewes.

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The practice of a 155-bed medium-sized rehabilitation hospital in Japan is investigated regarding stroke rehabilitation and the LLB from October 2001 to October 2003. Joint properties of cast Fe-Pt magnetic alloy laser welded to gold alloys. Prostate specific antigen decreases as hemoglobin A1c increases in men with type 1 diabetes pepcid dosage form mellitus. Semen analysis results from over 750 fathers in the USA demonstrated marked differences in the quality of semen from men at different locations and of different ethnic groups. Thus, the gastroenterologist must develop a keen understanding of bariatric surgical anatomy and physiology, as well as the expected postoperative side effects and potential complications experienced by the post-bariatric patient. It also can cause overcorrection in the basal inferior and lateral segments. Effect of fish oil supplementation on erythrocyte lipid pattern, malondialdehyde production and glutathione-peroxidase activity in psoriasis.

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To explore the clinical features and demography of PCS in athletes. Furthermore, VEGF immunoreactivity was attenuated by the treatment with FR173657. Zolpidem was administered according to the following age-based dosing schedule: 2.5 mg per dose for 2-4 year olds, 5.0 mg per dose for 5-10 year olds, and 10 mg per dose for older than 10 years. A growing body of evidence suggests that oxidative stress plays a key role in the pathogenesis of micro- and macrovascular diabetic complications. In this review macrolides, lincosamides, streptogramins, and tetracycline resistance genes and bacteria will be discussed with an emphasis on the resistance genes which are unique to environmental bacteria which are defined for this review as species and genera that are primarily found outside of humans and animals. The method is exemplified with images of bruising damage in fruits and of biological activity in germinating corn seeds. Comparison of radiographic and clinical characteristics of low-risk and high-risk cystic fibrosis genotypes.

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Flexible supercapacitor made of carbon nanotube yarn with internal pores. Functional Evolution of BRCT Domains from Binding DNA to Protein. Surveillance and norfloxacin brand name management of multidrug-resistant microorganisms. Our examples reveal that stress measurements enhance, support and clarify the interpretation of quantitative structural data. Nutrient supply differentially alters the dynamics of co-infecting phytoviruses.

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Involvement of ethylene in stress-induced expression of the TLC1.1 retrotransposon from Lycopersicon chilense Dun. The largest color difference was observed in the light-polymerized composite provisional material. The molecular mechanisms by which somatostatin may exert its anti-angiogenic effects, both indirect (through antagonism of the growth hormone axis) and direct (through direct antiproliferative and apoptotic effects on endothelial cells mediated by specific receptor subtypes) are described. Complications of acute intermittent porphyria, which is a defect of heme production, are due to the accumulation of heme intermediates often precipitated by medications. In cancer tissue, S1 may function as a positive element since ERRalpha-1 is expressed, but EAR-2 and RARgamma are only present in a small number of tumor specimens. This study aims to assess the nanotribology research output at global level using scientometric tools.

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