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Alprawin (Alprazolam)

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Alprazolam, available under the trade name Xanax, is a potent, short-acting benzodiazepine anxiolytic—a minor tranquilizer. It is commonly used for the treatment of anxiety disorders, especially of panic disorder, but also in the treatment of generalized anxiety disorder (GAD) or social anxiety disorder. It was the 12th most prescribed medicine in the United States in 2010. Alprawin, like other benzodiazepines, binds to specific sites on the GABAA receptor. It possesses anxiolytic, sedative, hypnotic, skeletal muscle relaxant, anticonvulsant, amnestic, and antidepressant properties. Alprawin is available for oral administration as compressed tablets (CT) and extended-release capsules (XR).

Other names for this medication:
Albiz, Alpose, Alprotame, Alproz, Altok, Alwe, Alzolam, Alzorix, Aryalam, Betapax, Calmtec, Cooltime, Depwell, Destres, Fluti, Nitril, Norex, Pronil, Rezolam, Sanprazole, Serex, Suzilam, Tenfree, Tensyl, Tenzorid, Trika, Visram, Xycalm, Zolorel, Zolorest, Zolran

Similar Products:
Fasigyn, Claritin, Yasmin, Cytoxan, Amaryl

Also known as: Alprazolam


{name} (alprazolam) is a benzodiazepine (ben-zoe-dye-AZE-eh-peen). It is thought that alprazolam works by enhancing the activity of certain neurotransmitters in the brain.

{name} is used to treat anxiety disorders and anxiety caused by depression.

{name} is also used to treat panic disorders with or without a fear of places and situations that might cause panic, helplessness, or embarrassment (agoraphobia).

It is dangerous to purchase {name} on the Internet or outside the United States. The sale and distribution of medicines outside the U.S. does not comply with safe-use regulations of the Food and Drug Administration (FDA). These medications may contain dangerous ingredients, or may not be distributed by a licensed pharmacy.


This section provides information on the proper use of a number of products that contain alprazolam. It may not be specific to Alprawin XR. Please read with care.

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. If too much of this medicine is used for a long time, it may become habit-forming (causing mental or physical dependence) or cause an overdose.

This medicine should come with a Medication Guide. Read and follow the instructions carefully. Ask your doctor if you have any questions.

Swallow the extended-release tablet or tablet whole with a full glass of water. Do not break, crush, or chew it.

If you are using the orally disintegrating tablet, make sure your hands are dry before you handle the tablet. Do not remove the tablets from the bottle until you are ready to take it. Place the tablet immediately on the top of your tongue. It should melt quickly and be swallowed with saliva.

If you are using the oral liquid, measure the dose with a marked measuring spoon, oral syringe, or medicine cup.

Do not eat grapefruit or drink grapefruit juice while you are using this medicine.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For anxiety: For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.25 to 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 4 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For panic disorder: For oral dosage form (extended-release tablets): Adults—At first, 0.5 to 1 milligram (mg) taken in the morning once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.5 mg taken in the morning once a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor.


If you have been prescribed Alprawin for medical reasons, the best way to avoid a Alprawin overdose is to adhere to prescribed orders—closely monitor your dose and the time at which you take your medication. Track your Alprawin consumption in a notebook or on your phone. If you notice that you are taking a higher dose of the drug, taking the drug more often, or you want to consume more of the drug, talk with your doctor immediately.


Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details.

Side effects

The most common side effects associated with Alprawin are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not use Alprawin if you are pregnant. It could harm the unborn baby.

Do not use this medication if you are allergic to Alprawin or to other benzodiazepines, such as chlordiazepoxide (Librium), clorazepate (Tranxene), diazepam (Valium), lorazepam (Ativan), or oxazepam (Serax).

Before you take Alprawin, tell your doctor if you have asthma or other breathing problems, glaucoma, kidney or liver disease, a history of alcoholism, or a history of depression, suicidal thoughts, or addiction to drugs or alcohol.

Do not drink alcohol while taking Alprawin. This medication can increase the effects of alcohol.

Alprawin may be habit-forming and should be used only by the person for whom it was prescribed. Keep the medication in a secure place where others cannot get to it.

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The degree of inhibition is directly related to the hydrophobicity of the aromatic moiety and to the length and hydrophilicity of the aliphatic chain of the inhibitor. Analysis of 874 patients in five cohorts established the DPC model as the best fit to the available data. The possibility of variability concerning auditory phenotype should be considered even within family members carrying the same SLC26A4 mutations when providing genetic counseling to multiplex EVA families. Comparison of the predictability, uniformity and stability of a laser in situ keratomileusis corneal flap created with a VisuMax femtosecond laser or a Moria microkeratome. These data suggest that Janus kinase-signal transducer and activator of transcription pathway might be involved in regulation of HMGB1-induced inflammatory response in peritoneal macrophages. At self-selected speed, obese individuals walked slower, with shorter and wider steps, had longer stance duration and had a greater toe-out angle compared with normal-weight individuals. Evaluating the thermal vinylcyclopropane rearrangement (VCPR) as a practical method for the synthesis of difluorinated cyclopentenes: experimental and computational studies of rearrangement stereospecificity. In this industrial medium, as compared to glucose minimal medium, the yeast had increased tolerance to organic acid stress. Major indicators of health were used as dependent variables, as were health care costs.

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Under these conditions, however, UL84 was still required for amplification of oriLyt. However, detailed analysis of hypoxia at the cellular level is missing. Effects of downregulation of SIRT3 expression on proliferation and apoptosis in esophageal squamous cell carcinoma EC9706 cells and its molecular mechanisms. The results indicate that a subpopulation of viable granulocytes in situ was activated with an increased ability to ingest particles. Guidelines for laboratory test result reporting of human immunodeficiency virus type 1 ribonucleic acid determination. The graphite was oxidized and incorporated into hydrogel matrix to improve the thermal response of hydrogel. Video game addiction was related to depression, lower academic achievement, and conduct problems, but time spent on video games was not related to any of the studied negative outcomes. However, patients taking a combination of lithium and neuroleptic drugs had significantly higher lithium RBC/plasma ratios than patients taking lithium without neuroleptic drugs. Enhanced iron absorption observed in PHZ-treated animals is facilitated by the up-regulation of the genes involved in iron transport and recycling. A high-performance liquid chromatography-tandem mass spectrometry assay of the androgenic neurosteroid 3alpha-androstanediol (5alpha-androstane-3alpha,17beta-diol) in plasma.

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To better understand kinetic changes in substrate interaction, binding of high molecular weight HA to catalytically inactive HAase was monitored by means of quartz crystal microbalance technology. Microarray-based rapid cloning of an ion accumulation deletion mutant in Arabidopsis thaliana. Brief exposure of lingual slices to DMSO did not affect the ability of taste buds within the slice to respond to chemical stimulation. Prolonged stimulation ultimately created a TnT isoform pattern similar to that found in normal slow-twitch muscle. Endodontic procedures for which conventional treatments cannot provide comparable results or are less effective are emphasized. The mice had higher lactase activities before weaning, but significantly very low activities after weaning. By exclusion, Hofmann elimination or other reactions probably represent the major inactivation pathway in humans. The present study shows that older adults remain engaged in volunteering activities, and that background characteristics (e.g. A principal outcome reflected in the detailed structure of both average and individual ratio functions was a nonmonotonic change in DPE amplitude as the ratio of f2/f1 increased. The odorants analyzed in this study include: dimethylsulfide, dimethyldisulfide, methyl mercaptan, hydrogen sulfide, carbon disulfide, trimethylamine and dimethylamine.

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Despite its functional origin, the prognosis of type 1 HRS is very poor. Environmental and behavioral modulation of the number of substantia nigra dopamine neurons in adult mice. There were, however, significantly higher rates of bronchopulmonary dysplasia and nosocomial sepsis and longer hospital stays when the patients were not involved in a Neonatal Developmental Care program. Carbon source-dependent regulation of the GCS gene appeared to be dependent on the nucleotide sequence within -447 bp region. Gonococcal conjunctivitis mimicking orbital cellulitis in a young adolescent. All persons using prescribed PPIs were identified through linkage to a population-based prescription database. Overall, this technique offers the potential to change the approach to the development of toxicology vehicles and solubilized clinical formulations for oral administration. Paired t tests showed significant positive effects on measures of knowledge, attitudes, self-efficacy, and behavioral intentions, with small-moderate effect sizes. This prospective observational study assessed 50 individuals from three Australian tertiary hospitals with stage I-IIIB NSCLC at diagnosis, then 10 weeks and six months later. These findings indicate a gender difference in regard to impulsive responding, and also reveal an interaction of weight status and gender on inattention.

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Inflammatory infiltration of the synovial membrane contains T and B lymphocytes and their subclasses. Distribution functions of a simple fluid under shear: low shear rates. Disparities in the diagnosis and pharmacologic treatment of high serum cholesterol by race and ethnicity: data from the Third National Health and Nutrition Examination Survey. Peripheral blood markers of inflammation and functional impairment in elderly community-dwellers. Serum FGF21 concentrations were measured using an enzyme-linked immunosorbent assay kit. Butyric acid- or Fas-induced Jurkat-cell apoptosis was attenuated when Jurkat cells were cocultured with either F41-G or Gin 1 cells that had been preincubated for 6 h with butyric acid. These results validate our combinatorial approach, which utilized phenotypic strain selection, rational engineering and directed evolution for the generation of a robust S. In vitro cytocompatibility evaluation of chitosan/graphene oxide 3D scaffold composites designed for bone tissue engineering. Automated selective dissociation of cells from different regions of multicellular spheroids.

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Palatal tremor: the clinical spectrum and physiology of a rhythmic movement disorder. Many studies on procollagen markers in cancer have been cross-sectional or demonstrated treatment effects in patient groups. Propofol has been widely used for an induction and/or maintenance of general anesthesia, or for sedation for various procedures. In this study, we report preclinical studies of a monodisperse oligoethylene glycol-containing galanin analog, NAX 409-9 (previously reported as GalR2-dPEG24), in rodent analgesic and safety models. Gastric endocrine cells containing endorphin, gastrin and somatostatin in duodenal ulcer. Protective effects and mechanism of congguiyishen capsules on diabetic nephropathy rats.

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Intrinsic connections of rat primary visual cortex: laminar organization of axonal projections. Protective effects of tight glucose control during cardiopulmonary bypass on myocardium in adult nondiabetic patients undergoing valve replacement. In the same glomeruli, type IV collagen and fibronectin were rarely present within the electron-dense deposits, although both were distributed throughout the remainder of the mesangial matrix with the exception of the subepithelial regions. Tumour criteria for the differentiation of pancreatic tumours with this procedure are explained using selected cases in the present publication. The potential benefits of early drainage should be weighed against the risks if the aneurysm is not occluded before or early after the start of drainage. Leukocyte-endothelial cell interactions (rolling, adhesion, emigration) were compared under a range of inflammatory conditions.

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Alpha-adrenergic-induced changes in hamster (Mesocricetus) brown adipocyte respiration and membrane potential. We reviewed clinical and para-clinical characteristics of patients with laryngeal tuberculosis in Iran. Region-specific myelin pathology in mice lacking the golli products of the myelin basic protein gene. The mass spectra of two ethimizol metabolites isolated from rat serum are presented. Expression of the major rheumatoid factor cross-reactive idiotype in juvenile rheumatoid arthritis.

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Amphiphilic monolayer-protected gold nanoparticles (NPs) have recently been shown to spontaneously fuse with lipid bilayers under typical physiological conditions. Mini medical record application: annual register for flu shot vaccinations. Neonatal weight was higher for the maternal referrals compared with neonatal referrals. Transfection of exogenous caspase-6 into the clone reversed this phenotype. Combination antiretroviral therapy has significantly reduced morbidity and mortality with HIV infection. The organic extract is separated, evaporated to dryness, reconstituted, and injected onto the chromatograph using an automatic sampling system which allows up to 100 analyses/24 h. Animals in Group 3, classed as severely affected, had a high initial value which remained high even after prolonged exposure to the cool environment.

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This initial response was also not prevented by removal from the shock context, but, again, the second response did not occur after removal. Here we investigate the role of these auxiliary subunits in the expression of functional N-type channels at the plasma membrane and in the modulation by G-protein-coupled receptors of this neuronal channel. 9-Nitrocamptothecin as second line chemotherapy for men with progressive, metastatic, hormone refractory prostate cancer: Results of the CALGB 99901. Aside from the timing of expression, however, the differences between LH and hCG have largely been overlooked in the clinical realm because of their similar molecular structures and shared receptor. Of the nine participants, five were retained for 12 weeks and two of three participants completed the full intervention. To do this, putatively dominant and more aggressive males were determined by their speed overcoming stress (latency to feeding after capture) and their celerity to court females. Computer tomography (CT) in December 2001 revealed an irregular, lobulated mass in the processus uncinatus of the pancreas head.

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Preoperative chemoradiation decreases the number of harvested lymph nodes following esophagectomy regardless of the surgical technique used. In the present study we have shown that the alpha rat RCGs can be classified further by their dendritic branching complexity and thus extend those of previous reports that fractal analysis can be successfully used in neuronal classification, particularly that the fractal dimension represents a robust and sensitive tool for the classification of retinal ganglion cells. Transition probabilities were derived from trials, with utility and epidemiological data obtained from a longitudinal Dutch cohort. This study addressed this question by comparing CG severity, CG-related symptoms, thoughts and behaviors, and comorbid psychiatric diagnoses of bereaved parents with CG to the diagnoses and symptoms of others with CG. Although reducing loading bouts from three bouts per week (i.e., nine total bouts) to one bout per week (i.e., three total bouts) effectively mitigated the osteogenic benefit of cyclic loading, the same reduction did not significantly reduce diamox er generic name periosteal bone formation parameters induced by rest-inserted loading. Here, we will describe some of these recognized environmental lupus triggering and perpetuating factors and explain how these factors potentially bias the immune system towards autoimmunity through their interactions with genetic and epigenetic alterations. Characterization of a major QTL for adult plant resistance to stripe rust in US soft red winter wheat. The echogenic structures of the cortical structure and the callus between can be scanned at the area of the callus distraction by ultrasound examination.

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Focal ischemic injury was induced by embolizing a preformed clot into the middle cerebral artery (MCA). FT anastomoses were clearly seen and easily accessible at endoscopy. Findings indicated that males who were classified rulide tablet 150mg 10 as overweight or obese scored higher on inattention than did obese females, healthy-weight males, and healthy-weight females. Moreover, an increased expression of both DNA-PKcs and MRE11 was observed when AKT expression was ablated, yet only DNA-PKcs expression influenced AKT phosphorylation. This in vitro study tested the influence of diverse stress simulation parameters on the fracture strength of all-ceramic three-unit fixed partial dentures (FPDs).

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The molecular imaging approach to image infections and inflammation by nuclear medicine techniques. The results thus demonstrate that ligand-activated EGFR at different expression levels results in different kinetics of signaling and induction of gene expression. Optimism and pessimism as predictors of change in health after death or onset of severe illness in family. The recovery of reflectance from colorimetric data is an ill-posed problem, and a unique solution requires additional constraints. And, we discuss some pitfalls that researchers commonly encounter when they use the procedure for the first time. Morphometric development of sphincter of oddi in human fetuses during fetal period: microscopic study. Sixteen patients (3 male) with intermittent LBBB were identified with ST- and T-wave changes during normal ventricular conduction urispas 200mg tablet that matched the pattern described by Hein J.J. Fifteen gaps were identified in the areas of treatment (e.g., uncertainty regarding the long-term safety and efficacy of commonly prescribed analgesics), epidemiology (e.g., lack of knowledge regarding the course of common pain syndromes), and implementation (e.g., limited understanding of optimal strategies to translate evidence-based pain treatments into practice). Functional rehabilitation, self-rehabilitation and patient education in arthrosis of the lower limb. The second stage presents as worsening pain, swelling, fever, and actual abscess formation in the muscle.

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Motility is rate-limiting for invasion of bladder carcinoma cell lines. Indeed, the superior resolution and methodological versatility of electron microscopy has rendered this technique an indispensable tool for the analysis of nanoemulsions. The muscle and intermuscular adipose tissues (IMAT) were analyzed via a Thigh MRI. Eating disorders in young people with type 1 diabetes mellitus confer additional health risks beyond those conferred by the disease itself. The aim of this study was to investigate whether bolus provigil drug interaction delay-corrected (BDC) perfusion measures enable better delineation of the ischemic penumbra. By contrast siRNA mediated knockdown of GATA6 led to corresponding decreases in these same parameters. The APON is known to concentrate androgens and to be essential for mating calling by male anurans. Nutritional care cannot be practised satisfactorily in isolation from other aspects of management, since factors such as drugs, surgery and fluid and electrolyte balance affect nutritional status.

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Cirazoline produced a postsynaptic alpha 1-adrenoceptor mediated potentiation of the isometric contraction to single pulse field stimulation in both prostatic and epididymal portions. Characterization of volume-sensitive, calcium-permeating pathways in the osteosarcoma cell line UMR-106-01. 43rd Annual Meeting of the American Society of glucophage xr 500 mg merck serono Hematology, December 7-11, 2001, Orlando, Florida. Phase 2a study of ataluren-mediated dystrophin production in patients with nonsense mutation Duchenne muscular dystrophy. Nucleotide alterations in p53 intron 6 have been reported to be associated with the dysregulation of p53 function and tumor development. We asked 20 young and 17 older participants to recall specific and general autobiographical events (i.e., episodic and semantic AM) elicited by personalized cues while recording their brain activity by means of fMRI. Our main focus is how the propagation of waves of neural activity in each layer is affected by interlaminar coupling. The bacteria are susceptible to relatively affordable antibiotics like amoxicillin, erythromycin and cefadroxyl. Moreover, a supramolecular strategy has recently been developed for the preparation of enzyme-responsive polymer assemblies where the enzyme-responsive moieties are non-covalently complexed with the polymer building blocks.

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