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Alprawin (Alprazolam)
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Alprawin

Alprazolam, available under the trade name Xanax, is a potent, short-acting benzodiazepine anxiolytic—a minor tranquilizer. It is commonly used for the treatment of anxiety disorders, especially of panic disorder, but also in the treatment of generalized anxiety disorder (GAD) or social anxiety disorder. It was the 12th most prescribed medicine in the United States in 2010. Alprawin, like other benzodiazepines, binds to specific sites on the GABAA receptor. It possesses anxiolytic, sedative, hypnotic, skeletal muscle relaxant, anticonvulsant, amnestic, and antidepressant properties. Alprawin is available for oral administration as compressed tablets (CT) and extended-release capsules (XR).

Other names for this medication:
Albiz, Alpose, Alprotame, Alproz, Altok, Alwe, Alzolam, Alzorix, Aryalam, Betapax, Calmtec, Cooltime, Depwell, Destres, Fluti, Nitril, Norex, Pronil, Rezolam, Sanprazole, Serex, Suzilam, Tenfree, Tensyl, Tenzorid, Trika, Visram, Xycalm, Zolorel, Zolorest, Zolran

Similar Products:
Fasigyn, Claritin, Yasmin, Cytoxan, Amaryl

Also known as: Alprazolam

Description

{name} (alprazolam) is a benzodiazepine (ben-zoe-dye-AZE-eh-peen). It is thought that alprazolam works by enhancing the activity of certain neurotransmitters in the brain.

{name} is used to treat anxiety disorders and anxiety caused by depression.

{name} is also used to treat panic disorders with or without a fear of places and situations that might cause panic, helplessness, or embarrassment (agoraphobia).

It is dangerous to purchase {name} on the Internet or outside the United States. The sale and distribution of medicines outside the U.S. does not comply with safe-use regulations of the Food and Drug Administration (FDA). These medications may contain dangerous ingredients, or may not be distributed by a licensed pharmacy.

Dosage

This section provides information on the proper use of a number of products that contain alprazolam. It may not be specific to Alprawin XR. Please read with care.

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. If too much of this medicine is used for a long time, it may become habit-forming (causing mental or physical dependence) or cause an overdose.

This medicine should come with a Medication Guide. Read and follow the instructions carefully. Ask your doctor if you have any questions.

Swallow the extended-release tablet or tablet whole with a full glass of water. Do not break, crush, or chew it.

If you are using the orally disintegrating tablet, make sure your hands are dry before you handle the tablet. Do not remove the tablets from the bottle until you are ready to take it. Place the tablet immediately on the top of your tongue. It should melt quickly and be swallowed with saliva.

If you are using the oral liquid, measure the dose with a marked measuring spoon, oral syringe, or medicine cup.

Do not eat grapefruit or drink grapefruit juice while you are using this medicine.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For anxiety: For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.25 to 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 4 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For panic disorder: For oral dosage form (extended-release tablets): Adults—At first, 0.5 to 1 milligram (mg) taken in the morning once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.5 mg taken in the morning once a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor.

Overdose

If you have been prescribed Alprawin for medical reasons, the best way to avoid a Alprawin overdose is to adhere to prescribed orders—closely monitor your dose and the time at which you take your medication. Track your Alprawin consumption in a notebook or on your phone. If you notice that you are taking a higher dose of the drug, taking the drug more often, or you want to consume more of the drug, talk with your doctor immediately.

Storage

Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details.

Side effects

The most common side effects associated with Alprawin are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not use Alprawin if you are pregnant. It could harm the unborn baby.

Do not use this medication if you are allergic to Alprawin or to other benzodiazepines, such as chlordiazepoxide (Librium), clorazepate (Tranxene), diazepam (Valium), lorazepam (Ativan), or oxazepam (Serax).

Before you take Alprawin, tell your doctor if you have asthma or other breathing problems, glaucoma, kidney or liver disease, a history of alcoholism, or a history of depression, suicidal thoughts, or addiction to drugs or alcohol.

Do not drink alcohol while taking Alprawin. This medication can increase the effects of alcohol.

Alprawin may be habit-forming and should be used only by the person for whom it was prescribed. Keep the medication in a secure place where others cannot get to it.

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The degree of inhibition is directly related to the hydrophobicity of the aromatic moiety and to the length and hydrophilicity of the aliphatic chain of the inhibitor. Analysis of 874 patients in five cohorts established the DPC model as the best fit to the available data. The possibility of variability concerning auditory phenotype should be considered even within family members carrying the same SLC26A4 mutations when providing genetic counseling to multiplex EVA families. Comparison of the predictability, uniformity and stability of a laser in situ keratomileusis corneal flap created with a VisuMax femtosecond laser or a Moria microkeratome. These data suggest that Janus kinase-signal transducer and activator of transcription pathway might be involved in regulation of HMGB1-induced inflammatory response in peritoneal macrophages. At self-selected speed, obese individuals walked slower, with shorter and wider steps, had longer stance duration and had a greater toe-out angle compared with normal-weight individuals. Evaluating the thermal vinylcyclopropane rearrangement (VCPR) as a practical method for the synthesis of difluorinated cyclopentenes: experimental and computational studies of rearrangement stereospecificity. In this industrial medium, as compared to glucose minimal medium, the yeast had increased tolerance to organic acid stress. Major indicators of health were used as dependent variables, as were health care costs.

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To better understand kinetic changes in substrate interaction, binding of high molecular weight HA to catalytically inactive HAase was monitored by means of quartz crystal microbalance technology. Microarray-based rapid cloning of an ion accumulation deletion mutant in Arabidopsis thaliana. Brief exposure of lingual slices to DMSO did not affect the ability of taste buds within the slice to respond to chemical stimulation. Prolonged stimulation ultimately created a TnT isoform pattern similar to that found in normal slow-twitch muscle. Endodontic procedures for which conventional treatments cannot provide comparable results or are less effective are emphasized. The mice had higher lactase activities before weaning, but significantly very low activities after weaning. By exclusion, Hofmann elimination or other reactions probably represent the major inactivation pathway in humans. The present study shows that older adults remain engaged in volunteering activities, and that background characteristics (e.g. A principal outcome reflected in the detailed structure of both average and individual ratio functions was a nonmonotonic change in DPE amplitude as the ratio of f2/f1 increased. The odorants analyzed in this study include: dimethylsulfide, dimethyldisulfide, methyl mercaptan, hydrogen sulfide, carbon disulfide, trimethylamine and dimethylamine.

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Despite its functional origin, the prognosis of type 1 HRS is very poor. Environmental and behavioral modulation of the number of substantia nigra dopamine neurons in adult mice. There were, however, significantly higher rates of bronchopulmonary dysplasia and nosocomial sepsis and longer hospital stays when the patients were not involved in a Neonatal Developmental Care program. Carbon source-dependent regulation of the GCS gene appeared to be dependent on the nucleotide sequence within -447 bp region. Gonococcal conjunctivitis mimicking orbital cellulitis in a young adolescent. All persons using prescribed PPIs were identified through linkage to a population-based prescription database. Overall, this technique offers the potential to change the approach to the development of toxicology vehicles and solubilized clinical formulations for oral administration. Paired t tests showed significant positive effects on measures of knowledge, attitudes, self-efficacy, and behavioral intentions, with small-moderate effect sizes. This prospective observational study assessed 50 individuals from three Australian tertiary hospitals with stage I-IIIB NSCLC at diagnosis, then 10 weeks and six months later. These findings indicate a gender difference in regard to impulsive responding, and also reveal an interaction of weight status and gender on inattention.

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Inflammatory infiltration of the synovial membrane contains T and B lymphocytes and their subclasses. Distribution functions of a simple fluid under shear: low shear rates. Disparities in the diagnosis and pharmacologic treatment of high serum cholesterol by race and ethnicity: data from the Third National Health and Nutrition Examination Survey. Peripheral blood markers of inflammation and functional impairment in elderly community-dwellers. Serum FGF21 concentrations were measured using an enzyme-linked immunosorbent assay kit. Butyric acid- or Fas-induced Jurkat-cell apoptosis was attenuated when Jurkat cells were cocultured with either F41-G or Gin 1 cells that had been preincubated for 6 h with butyric acid. These results validate our combinatorial approach, which utilized phenotypic strain selection, rational engineering and directed evolution for the generation of a robust S. In vitro cytocompatibility evaluation of chitosan/graphene oxide 3D scaffold composites designed for bone tissue engineering. Automated selective dissociation of cells from different regions of multicellular spheroids.

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Palatal tremor: the clinical spectrum and physiology of a rhythmic movement disorder. Many studies on procollagen markers in cancer have been cross-sectional or demonstrated treatment effects in patient groups. Propofol has been widely used for an induction and/or maintenance of general anesthesia, or for sedation for various procedures. In this study, we report preclinical studies of a monodisperse oligoethylene glycol-containing galanin analog, NAX 409-9 (previously reported as GalR2-dPEG24), in rodent analgesic and safety models. Gastric endocrine cells containing endorphin, gastrin and somatostatin in duodenal ulcer. Protective effects and mechanism of congguiyishen capsules on diabetic nephropathy rats.

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Intrinsic connections of rat primary visual cortex: laminar organization of axonal projections. Protective effects of tight glucose control during cardiopulmonary bypass on myocardium in adult nondiabetic patients undergoing valve replacement. In the same glomeruli, type IV collagen and fibronectin were rarely present within the electron-dense deposits, although both were distributed throughout the remainder of the mesangial matrix with the exception of the subepithelial regions. Tumour criteria for the differentiation of pancreatic tumours with this procedure are explained using selected cases in the present publication. The potential benefits of early drainage should be weighed against the risks if the aneurysm is not occluded before or early after the start of drainage. Leukocyte-endothelial cell interactions (rolling, adhesion, emigration) were compared under a range of inflammatory conditions.

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Alpha-adrenergic-induced changes in hamster (Mesocricetus) brown adipocyte respiration and membrane potential. We reviewed clinical and para-clinical characteristics of patients with laryngeal tuberculosis in Iran. Region-specific myelin pathology in mice lacking the golli products of the myelin basic protein gene. The mass spectra of two ethimizol metabolites isolated from rat serum are presented. Expression of the major rheumatoid factor cross-reactive idiotype in juvenile rheumatoid arthritis.

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The molecular imaging approach to image infections and inflammation by nuclear medicine techniques. The results thus demonstrate that ligand-activated EGFR at different expression levels results in different kinetics of signaling and induction of gene expression. Optimism and pessimism as predictors of change in health after death or onset of severe illness in family. The recovery of reflectance from colorimetric data is an ill-posed problem, and a unique solution requires additional constraints. And, we discuss some pitfalls that researchers commonly encounter when they use the procedure for the first time. Morphometric development of sphincter of oddi in human fetuses during fetal period: microscopic study. Sixteen patients (3 male) with intermittent LBBB were identified with ST- and T-wave changes during normal ventricular conduction urispas 200mg tablet that matched the pattern described by Hein J.J. Fifteen gaps were identified in the areas of treatment (e.g., uncertainty regarding the long-term safety and efficacy of commonly prescribed analgesics), epidemiology (e.g., lack of knowledge regarding the course of common pain syndromes), and implementation (e.g., limited understanding of optimal strategies to translate evidence-based pain treatments into practice). Functional rehabilitation, self-rehabilitation and patient education in arthrosis of the lower limb. The second stage presents as worsening pain, swelling, fever, and actual abscess formation in the muscle.

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Cirazoline produced a postsynaptic alpha 1-adrenoceptor mediated potentiation of the isometric contraction to single pulse field stimulation in both prostatic and epididymal portions. Characterization of volume-sensitive, calcium-permeating pathways in the osteosarcoma cell line UMR-106-01. 43rd Annual Meeting of the American Society of glucophage xr 500 mg merck serono Hematology, December 7-11, 2001, Orlando, Florida. Phase 2a study of ataluren-mediated dystrophin production in patients with nonsense mutation Duchenne muscular dystrophy. Nucleotide alterations in p53 intron 6 have been reported to be associated with the dysregulation of p53 function and tumor development. We asked 20 young and 17 older participants to recall specific and general autobiographical events (i.e., episodic and semantic AM) elicited by personalized cues while recording their brain activity by means of fMRI. Our main focus is how the propagation of waves of neural activity in each layer is affected by interlaminar coupling. The bacteria are susceptible to relatively affordable antibiotics like amoxicillin, erythromycin and cefadroxyl. Moreover, a supramolecular strategy has recently been developed for the preparation of enzyme-responsive polymer assemblies where the enzyme-responsive moieties are non-covalently complexed with the polymer building blocks.

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