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Alsartan

Alsartan is a moderately priced drug used to treat high blood pressure. This drug is also used to treat patients with heart failure and patients who have had a heart attack. This drug is more popular than comparable drugs. It is available in brand and generic versions. It is not covered by most Medicare and insurance plans, but manufacturer and pharmacy coupons can help offset the cost.

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Also known as: Valsartan

Description

{name} (valsartan) is an angiotensin II receptor blocker (sometimes called an ARB). Valsartan keeps blood vessels from narrowing, which lowers blood pressure and improves blood flow.

{name} is used to treat high blood pressure (hypertension) in adults and children who are at least 1 year old. Lowering blood pressure may lower your risk of a stroke or heart attack.

{name} is also used in adults to treat heart failure and lower your risk of needing to be hospitalized, and to lower your risk of death after a heart attack.

Dosage

Usual Adult Dose for Congestive Heart Failure:

Initial dose: 40 mg orally twice a day Maintenance dose: 80 to 160 mg twice a day. The dose should be increased to the highest dose tolerated by the patient.

Usual Adult Dose for Hypertension:

Initial dose: 80 to 160 mg orally once a day. Maintenance dose: 80 to 320 mg orally once a day

Usual Adult Dose for Myocardial Infarction:

Initial dose: 20 mg orally twice a day Maintenance dose: The initial dosage may be titrated upward within 7 days to 40 mg twice daily, with subsequent titrations to a target maintenance dose of 160 mg twice a day as tolerated by the patient. If symptomatic hypotension or renal dysfunction occurs, consideration should be given to a dosage reduction. Comment: Valsartan may be initiated as early as 12 hours after a myocardial infarction, and may be given with other standard postmyocardial infarction treatment, including thrombolytics, aspirin, beta blockers, and statins.

Usual Pediatric Dose for Hypertension:

6 to 16 years: Initial dose: 1.3 mg/kg once a day (up to 40 mg) Maintenance dose: up to 2.7 mg/kg (up to 160 mg) once a day titrated according to patient response Comments: If the calculated dosage does not correspond to the available tablet strengths, or if children are unable to swallow tablets, the use of a suspension (which can be prepared from the tablets) is recommended. The valsartan dose may need to be increased if the suspension is replaced by a tablet. No data are available in pediatric patients either undergoing dialysis or with a glomerular filtration rate less than 30 mL/min.

Detailed Alsartan dosage information

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include fast heartbeats or fainting.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Keep your medicine container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Alsartan are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not take Alsartan if you are allergic to Alsartan components. Do not take Alsartan if you're pregnant or you plan to have a baby, or you are a nursing mother. Alsartan can harm your baby. Take Alsartan with care if you are taking any other blood pressure medications: diuretic (water pill) such as amiloride (Midamor), spironolactone (Aldactone), triamterene (Dyrenium, Maxzide, Dyazide), angiotensin-converting enzyme (ACE) inhibitors such as benazepril (Lotensin), captopril (Capoten), enalapril (Vasotec), fosinopril (Monopril), lisinopril (Prinivil, Zestril), moexipril (Univasc), perindopril (Aceon), quinapril (Accupril), and trandolapril (Mavik); beta blockers such as atenolol (Tenormin), labetalol (Normodyne), metoprolol (Lopressor, Toprol XL), nadolol (Corgard), propranolol (Inderal), ramipril (Altace). Be careful with Alsartan if you suffer from or have a history of liver disease, kidney disease. Do not use potassium supplements or salt substitutes. If you want to achieve most effective results without any side effects it is better to avoid alcohol. Do not stop taking Alsartan suddenly.

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With higher lidocaine concentrations, changes in Vmax continued to be an exponential function of recovery interval, whereas changes in conduction time consistently deviated from the terminal exponential relationship at short diastolic intervals. The oto-vertebral syndrome is a rare combination of malformations of the ears, spinal anomalies, and congenital heart disease. Antireflux procedure in surgical correction of long lower ureteral defects. The histopathological features, treatment and prognosis of this unusual malignancy are reviewed. This report describes the experience of managing two pediatric patients with HIT that underwent cardiovascular procedures requiring anticoagulation. Many factors probably have an important role, including somatic mutation, epigenetic modulations, interactions with normal stroma, and environmental stimuli.

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The periodic health examination: a comparison of United States and Canadian recommendations. The Questionnaire on Eating and Weight Patterns-Revised can be useful in a first-step screening procedure to identify probable cases of binge eating. Coronary perfusion is impaired in patients with aortic stenosis (AS). Physicians demonstrate variability in interpretation for the need for informed consent and frequently lack formal training in communicating informed consent. The aims of this study are to calculate the sensitization rates to Compositae mix and SL mix in an occupational dermatology clinic and to describe cases of active sensitization caused by patch testing with Compositae mix and SL mix. Focal cortical dysplasia (CD) is characterized by the presence of dysmorphic neurons, laminar and columnar disorganization. Quantifying the rhythm of KaiB-C interaction for in vitro cyanobacterial circadian clock. The Arg----Trp replacement found in the thrombin portion of prothrombin Tokushima appears to reduce its interaction with various substrates including fibrinogen and platelet receptors and accounts for the recurrent bleeding episode observed in the propositus. The mechanism of this regional dysfunction is poorly understood. Changes in biological markers of health: older Americans in the 1990s.

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Identification of color centers on MgO(001) thin films with scanning tunneling microscopy. ANN and genetic algorithms can reveal parsimonious variable sets accurate for predicting urinary tract infection, and novel relationships between symptoms, urinalysis findings, and infection. Mechanistic investigations on the end-to-end assembly of Au nanorods to nanochains, in the presence of alpha,omega-alkanedithiols, were reported. The expression of surface antigens on three trophoblastic tissues in the mouse. An overview of methods for interval-censored data with an emphasis on applications in dentistry.

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Thiafatty acids as tracers to investigate biosynthetic pathways of lepidopteran sex pheromones. Iron supplements reduce erythrocyte copper-zinc superoxide dismutase activity in term, breastfed infants. Intensive insulin therapy significantly improves endothelial injury/dysfunction as measured by vWF in early stage type 2 diabetes. For a target gene, several siRNAs must be designed according to the empirical rules. The patho-physiological background of NIV and the equipment required technology are described. The biomechanics of the spinal cord and its membranes in the spinal canal. Using a TE of 31 ms, no differences were found in glutamate/NAA (Glx/NAA), Glx/Cho, myo-inositol/NAA (mI/NAA), and mI/Cho ratios between neonates with a good and those with a poor outcome. Progestin effects on growth in the human breast cancer cell line vantin medication class T-47D--possible therapeutic implications. Due to the lognormal distribution of epiphytic bacterial populations, estimates of population size based on the common practice of using bulked samples (wherein several leaves are washed together) will overestimate the population median by a factor of approximately 1.15sigma. A variety of cell types have been used in various research models to affect matrix repair of the intervertebral disc.

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Immunochemical similarity between a gastric mucosa non-pepsin acid proteinase and neutrophil cathepsin E of the rat. This asymmetry implies that the hemispheric autonomic control of the face differs and could influence the expression of emotion. In our experience, it appears that heterotopic renal autotransplantation by which normal arterial perfusion distal to the dissection is reestablished is a good therapeutic option for reperfusion of the ischemic kidney compromised by a progressive dissection of the thoracoabdominal aorta. During the period January 1980-June 1981, an investigation was made of skin diseases among employees of a film laboratory. Isothermal desorption measurements of self-diffusion in supercooled o-terphenyl. We show that the majority of error sources cause relatively small magnitude peak-to-valley errors in measurement of the order of 0.002-0.005lambda. The study included 650 Egyptian females between 16 and 55 years of age (333 genitally cut women and 317 uncut women). Our data further indicate that PARP-1, probably through topoisomerase I interactions rather than poly(ADP-ribosyl)ation, prevents p53 from stimulating spontaneous HR on chromosomes via topoisomerase I activity. A marked loss of keratin production was evident in the tumours that expressed p16.

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The laser-induced movement of CO molecules over a platinum surface was followed in real time by means of ultrafast vibrational spectroscopy. A mechanical testing machine was used to apply moments to the model at a controlled loading rate. Psychological stress is a major risk factor for cardiovascular disease (CVD), with multiple behavioral and physiological mediators. Binding constants measured by these methods will help predict the behavior of monoclonal antibodies in immunoassays and in experiments where monoclonal antibody is injected in vivo for imaging or pharmacologic delivery. In this study, we have developed the physicochemical nitrogen removal process to remove the nitrogen content for a real industrial wastewater. The effect of radiation on lenticular epithelial enzymes in young rabbits. ECT during the index hospitalization was associated with greater improvement in depressive symptoms and in most measures of QOL. It is concluded that extended treatment with dalteparin is useful as a bridge to revascularization in this high-risk subgroup of patients with unstable coronary artery disease.

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The prognostic importance of obesity after primary percutaneous coronary intervention (PCI) in patients with acute myocardial infarction (AMI) is unknown. Moreover, the year in which the cancer rate starts decreasing is more recent in the older age groups. In 75 patients with circulatory insufficiency of various degree the diuretic effect of moduretic was studied. The results obtained indicate that HNE might be important factor affecting intestinal barrier integrity, while stobadine could efficiently protect intestinal cells against harmful HNE effects. Letter: Enzyme variations produced in epidermis by soft x-ray collimated beams. Effect of cisapride on morphine-induced delay in gastric emptying. ACTH and cortisol secretion rates, analytical dose-response estimates of endogenous ACTH efficacy (maximal cortisol secretion), dynamic ACTH potency, and adrenal sensitivity (slope term) from 24-h ACTH-cortisol profiles were quantified. The interaction of sympathetic stimulation and blockade on the calcium uptake of the sarcoplasmic reticulum. Immunological suppression of parasite rejection by removal of selected lymphocyte populations: the effect of neonatal thymectomy and anti-thymocyte serum administration on the resistance of rats to infection with the nematode, Nippostrongylus brasiliensis. The relationship between predicted TNFalpha genotype and circulating TNFalpha levels in patients undergoing coronary revascularization surgery has yet to be defined.

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When associated with relative macrocephaly, the phenotype resembles Silver-Russell syndrome (SRS). The numerical dynamics of rosette-forming cells after primary and secondary immunization of mice and administration of the serotonin precursor 5-hydroxytryptophan. Although small-scale observational studies have suggested a beneficial impact of vitamin D supplementation on the incidence and severity of multiple sclerosis, large scale clinical trials remain warranted to confirm these preliminary results. The free energy of the adsorption process of an ionic surfactant from aqueous solutions onto a set of carbon blacks in the range of low concentrations was evaluated using the model proposed by van Oss and co-workers. Parallel synthesis and rapid photochemical screening of organosoluble Ru(II) photosensitizers.

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