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Amicon (Amitriptyline)

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Amicon is an antidepressant medication that is sometimes prescribed off-label to manage chronic back pain. It is one of the drugs in a class of drugs known as tricyclic antidepressants. Amicon is not a narcotic (opioid) drug, and there is not usually an addiction risk with the medication.

Other names for this medication:
Amicon, Amimax, Amitar, Amitop, Amitrol, Amitryn, Amiwel, Amize, Amizep, Amrea, Chlotrip, Eliwel, Emotrip, Estiline, Libotryp, Librodep, Limbival, Maxitrip, Normaline, Raitrip, Sarotena, Tryline, Tryptomec, Typlin, Vanatrip

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Also known as: Amitriptyline


{name} (amitriptyline) is a tricyclic antidepressant with sedative effects. Amitriptyline affects certain chemical messengers (neurotransmitters) that communicate between brain cells and help regulate mood.

{name} is a prescription medicine used to treat symptoms of depression.


Usual Adult Dose for Depression:

OUTPATIENTS: -Initial dose: 75 mg orally per day in divided doses; this may be increased to 150 mg/day (if needed) -Maintenance dose: 40 to 100 mg orally per day -Maximum dose: 150 mg/day Alternate outpatient treatment regimen: 50 to 100 mg orally as a single dose at bedtime; this may be increased by 25 or 50 mg as needed at bedtime to a total of 150 mg/day INPATIENTS: -Initial dose: 100 mg orally per day -Maintenance dose: 40 to 100 mg orally as a single dose at bedtime -Maximum dose: 300 mg/day Comments: -Dose increases should preferably be made in the late afternoon or at bedtime due to the sedative effect. -The full therapeutic effect may take as long as 30 days to develop. -Maintenance doses should be reduced to the lowest amount that will maintain relief of symptoms when satisfactory improvement has been obtained. -Maintenance therapy should be continued for 3 months or longer to lessen the possibility of relapse. Use: Relief of symptoms of depression

Usual Geriatric Dose for Depression:

10 mg orally 3 times a day AND 20 mg orally once a day at bedtime Comments: -The full therapeutic effect may take as long as 30 days to develop. -Elderly patients should be monitored carefully and serum levels obtained as clinically appropriate. -Dose adjustments should be made according to clinical response. Use: Relief of symptoms of depression

Usual Pediatric Dose for Depression:

12 years or older: 10 mg orally 3 times a day AND 20 mg orally once a day at bedtime Comments: -The full therapeutic effect may take as long as 30 days to develop. -Dose adjustments should be made according to clinical response. Use: Relief of symptoms of depression

Detailed Amicon dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of amitriptyline can be fatal.

Overdose symptoms may include irregular heart rhythm, feeling like you might pass out, seizures, or coma.


Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Amicon are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not take Amicon if you are allergic to Amicon components. Do not take Amicon if you are pregnant, planning to become pregnant, or are breast-feeding. Be careful with Amicon if you suffer from or have a history of a history of heart attack, stroke, bipolar disorder (manic-depression), schizophrenia or other mental illness, diabetes, overactive thyroid, glaucoma, problems with urination, heart disease, seizures. Be careful with Amicon if you are taking guanethidine (Ismelin), disulfiram (Antabuse), heart rhythm medications such as flecainide (Tambocor), propafenone (Rhythmol), quinidine (Cardioquin, Quinidex, Quinaglute), cimetidine (Tagamet). Avoid alcohol. Be careful! Taking Amicon you can become suicidal. Be careful when you are driving or operating machinery. Be careful with Amicon if you are going to have a surgery. It can be dangerous to stop Amicon taking suddenly.

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Fatal nonocclusive mesenteric ischaemia: population-based incidence and risk factors. B cell differentiation is controlled by a complex network of lineage-restricted transcription factors. Involvement of postnatal gonads in the maturation of dopaminergic regulation of prolactin secretion in female rats. Human cardiac myocytes and neonatal rat cardiac myocytes were exposed to hydrogen peroxide with or without pre-treatment with recombinant human neuregulin-1 (rhNRG-1). Additional factors are iron deficiency and iatrogenic factors, e.g. Performance of a cognitive, but not visual, secondary task interacts with alcohol-induced balance impairment in novice and experienced motorcycle riders.

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Oxidation of alpha-1-proteinase inhibitor: significance for pathobiology. Degenerative changes, or spondylosis, are the most common causes of these symptoms throughout the spinal axis, but these changes are encountered least frequently in the thoracic region. Theory of magnetodynamics induced by spin torque in perpendicularly magnetized thin films. This allowed both the means and the proportions to vary across levels of the covariates. The difference peaks represented mostly small changes in various protein surface groups and in the adjacent solvent regions, and some displayed convincing evidence of binding of the guanidinium ion to the protein. One of the criticisms of this research is that the exposure has not been represented by measures of infection. So-called HFHLL, better termed haemosiderotic fibrolipomatous tumour, is a distinct lesion characterized by an admixture of fibroblastic spindle cells, mature adipocytes and haemosiderin pigmentation, shows a predilection for the distal extremities and quite often recurs locally. We also found that high basal (lowest observed in triplicate cores) Ki67 expression was more strongly associated with improved 5-year disease-specific survival than hot-spot and average Ki67 measurements.

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Congenital heart defects still constitute serious medical problems. Although the shapes of polarized cells display extraordinary diversity, the key molecules involved in cell polarity are relatively well conserved. Purification of bovine thyrotropin and study of some properties of this hormone. These residues were previously identified by mutational analysis as significant for stabilization of the enzyme-carbohydrate complex, with Glu105 and Glu109 being the catalytic residues. Participants memorized lists of intermixed visual and auditory words with either an elaborative or rote rehearsal strategy. To determine whether ALK-positive NSCLC is also sensitive to pemetrexed, we retrospectively evaluated progression-free survival (PFS) of ALK-positive versus ALK-negative patients who had been treated with pemetrexed-based chemotherapy for advanced NSCLC.

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A case of acute gonococcal flexor tenosynovitis without joint involvement is presented. Patients who fell in between these two values require further monitoring with conventional calcium levels. A new class of macrocyclic lanthanide complexes for cell labeling and magnetic resonance imaging applications. State of the cardiovascular and nervous systems from the use of individual meand of protection. Therapeutical possibilities and side effects of intrafocal BCG-vaccination into metastases of malignant melanomas are discussed. Effects of ionizing radiation on bacterial DNA-membrane complexes.

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Gender and marital status differences in control and distress: common stress versus unique stress explanations. Erythrocyte-endothelial cell adherence in senescence and in hemolytic disorders. The metabolic effect of low-dose ethinyl estradiol was studied (estrogen suppressed testosterone, luteinizing hormone, and follicle-stimulating hormone). Fifteen per cent of the patients had high or moderate disease activity in all 3 yr, indicating a need for more aggressive early anti-rheumatic therapy. We propose that the addition of the polyglycine chain can promote the binding of g14-3-3 to alternative ligands and that the differential rate of polyglycylation/deglycylation during the encystation process can act as a novel mechanism to regulate the intracellular localization of g14-3-3. Molecular modeling allowed prediction of the tenormin drug form structure of the mutant IRE in affected cases.

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Experimental research on the influence of some antiblastics on production of agglutinating and hemolyzing antibodies. Group crisis intervention in a school setting following an attempted suicide. The entire assay can be accomplished within 24 h with a sensitivity of 1 ng/ml in milk and in the cheese extract or 1.3 ng/ml in the chicken salad extract. Phrenic paralysis after heart surgery with extracorporeal circulation. Most of the remaining assistance was in the form of obligated or unobligated grants and scholarships, with an increasing share attributable to grants/scholarships with obligations following graduation. Embolized vessels remained occluded 2 days following embolization. It presents an operational analysis of the Dexamethasone Suppression Test as utilized at a state hospital.

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More attention should be paid to the young men of Han and Uygur on prevention of dyslipidemia, in Xinjiang. To reduce mortality related to delay in diagnosis and treatment, medical providers need to be educated about blastomycosis, with an emphasis on symptom recognition, methods of diagnosis, and appropriate antifungal treatment. Assessment of normal flow patterns in the pulmonary circulation by using 4D magnetic resonance velocity mapping. An MRI of the temporal bone demonstrated a tiny isointense intracanalicular tumor with inhomogeneous enhancement. Algorithms exist for the deformation of dose based on patient image sets, though these are sometimes contentious because not all such image calculations are constrained by physical laws. Neurological development up to the age of four years of extremely low birthweight infants born in Southern Finland in 1991-94 maximum dosage of altace . Grouping by developmental level produced more statistical differences than did grouping by age. With little ambiguity, the lowest energy conformer is therefore predicted to be the dominant conformation, consistent with the diffraction data available for C6H12, C10H20, C12H24, and C14H28. has a wider range of optimum conditions and is also more resistant to extreme environmental variables. We searched for the residual fragment by real-time fluoroscopic examination.

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Thirty enumeration areas within the study location were randomly picked and their boundaries were defined with the assistance of the National Population Commission (NPC) Officials. Bilateral undescended testes classified according to preoperative and postoperative status of gonadotropins and inhibin B in relation to testicular histopathology at bilateral orchiopexy in infant boys. Under voltage clamp noradrenaline elicited an inward current, which persisted in 18 mM external potassium with the membrane potential set at the potassium equilibrium potential. This research was designed in consultation with service users and employed a qualitative, phenomenological, and idiographic design using semi-structured interviews. We propose that treatment sustaining secretion of endogenous vitronectin or direct application of exogenous vitronectin may be a method to augment regeneration of the severed optic axons. Here, we focused on HCMV-encoded unique short (US) 2 and US11, which bind newly synthesized MHC class I heavy chains (HCs) and support their dislocation into the cytosol for subsequent degradation by proteasomes. RNA polymerases in the germinal vesicle contents of Rana pipiens oocytes. Visually evoked cortical response in light-adapted cat and liminal brightness discrimination. Acute canine model for drug-induced Torsades de Pointes in drug safety evaluation-influences of anesthesia and validation with quinidine and astemizole. Moreover, the TAN-1 and int-3 oncogenes represent activated versions of Notch1 and Notch4, respectively.

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Clinical and neuro investigational profile of patients suggested a low incidence of HSV-1 encephalitis in the study group. Vagotomy and capsaicin treatment attenuate dorsal vagal complex (DVC) but not myenteric Fos-like immunoreactivity (Fos-LI) induced by cholecystokinin-8 (CCK-8). These data indicate that the defective AMLR observed in patients with RA is related to disease activity and is associated with altered cellular interactions among T lymphocytes, macrophages, and the B lymphocyte-enriched population. To clarify the clinical feature, diagnosis and therapy of the pulmonary cryptococcosis (PC). Despite the fact that intracerebral hemorrhage (ICH) is the deadliest and least treatable of all stroke subtypes, historically researchers have directed most of their efforts toward ischemic strokes.

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Although none of the patients exhibited symptoms of acquired immune deficiency, 5 of them showed an abnormally low proportion of T-cells with reversal of the OKT4 (helper/inducer) to OKT8 (cytotoxic/suppressor) ratio. Brachial plexus injuries are devastating injuries that affect primarily young healthy males. The first incorporates pleiotropic effects of a Y-linked locus, such that viability, segregation distortion, fecundity and sexual selection can all be determined by one locus. The chronic low back pain syndrome: identification and management. Both therapies have integrated acceptance-based mindfulness approaches with change-based cognitive and behavioural therapies to create efficacious treatments. Results may hold the potential of offering an instrument for treating MOH patients in the general population by GPs. However, the cellular mechanisms that link Nox activation with plasma membrane receptor signaling remain poorly defined. Sudden hydrocephalus caused by an isolated cysticerous of the 4th ventricle. New class of competitive inhibitor of bacterial histidine kinases. Observational cohort study using ANZDATA (Australia and New Zealand Dialysis and Transplant) Registry data.

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All lesions extended from the medulla oblongata to the basal nuclei/parietal cortex area. It is important to note that the adsorption capacities presented in this paper vary, depending on the characteristics of the individual adsorbent, the extent of surface modification and the initial concentration of the adsorbate. Effect of a glucosyltransferase inhibitor on glucan synthesis and cellular adherence of Streptococcus mutans. An 84-year-old man with a history of permanent pacemaker placement had a preoperative cardiac evaluation for prostate cancer surgery. When retested with a novel target action, also the previously successful subject failed to copy--and he did so across several contexts. The in-build electrical readout of the piezoresistive cantilevers provides a convenient alternative to the conventional optical detection, and the presented method offers the possibility of detecting protein conformational changes using miniaturized microarrays. With a polygon rotational speed of 900 revolutions per second, a continuous wavelength tuning rate of 9200 nm/ms and a tuning repetition rate of 115 kHz were achieved. Recent proteomic studies of detergent resistant membrane fractions have begun to characterize the protein composition of caveolae and lipid rafts.

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Anthelminthic treatment may induce a host reaction with inflammation and deterioration of the clinical picture and has to be performed cautiously and under protection with corticosteroids. We discuss the implications of sequence haplotypes and STS markers for the generation of high-density maps in cereals. In carcinomas, the influences of the microenvironment are mediated, in large anxiety medication xanax side effects part, by paracrine signaling between epithelial tumor cells and neighboring stromal fibroblasts. The AED represents an efficient method of delivering defibrillation to persons experiencing out-of-hospital cardiac arrest and its use by both traditional and nontraditional first responders appears to be safe and effective. LDL cholesterol is a well-established risk factor for myocardial infarction, but not for stroke.

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