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Angizem (Diltiazem)

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Angizem hydrochloride is a first generation calcium channel blocker that is widely used in the therapy of hypertension and angina pectoris. Angizem therapy is associated with serum enzyme elevations and has been linked to rare instances of clinically apparent liver injury.

Other names for this medication:
Altiazem, Angizem, Cardem, Cardiorex, Cartia, Coriem, Dicard, Dilacor, Dilcardia, Dilcontin, Dilcor, Dilgard, Dilocor, Dilter, Diltia, Diltiaz, Diltiazem, Dilticard, Diltime, Diltp, Dilzem, Heartil, Icidil, Ionozem, Kaizem, Masdil, Onzem, Taztia, Tiamate, Tiazac

Similar Products:
Keflex, Xanax, Cozaar, Cycrin, Temovate, Biaxin, Dostinex, Aldara

Also known as: Diltiazem


Diltiazem is used alone or together with other medicines to treat angina (severe chest pain) or hypertension (high blood pressure). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled.

Diltiazem is a calcium channel blocker. It works by affecting the movement of calcium into the cells of the heart and blood vessels. As a result, diltiazem relaxes the blood vessels and increases the supply of blood and oxygen to the heart while reducing its workload.

This medicine is available only with your doctor's prescription.


This section provides information on the proper use of a number of products that contain diltiazem. It may not be specific to Angizem LA. Please read with care.

In addition to the use of this medicine, treatment for your high blood pressure may include weight control and changes in the types of foods you eat, especially foods high in sodium (salt). Your doctor will tell you which of these are most important for you. You should check with your doctor before changing your diet.

Many patients who have high blood pressure will not notice any signs of the problem. In fact, many may feel normal. It is very important that you take your medicine exactly as directed and that you keep your appointments with your doctor even if you feel well.

Remember that this medicine will not cure your high blood pressure, but it does help control it. You must continue to take it as directed if you expect to lower your blood pressure and keep it down. You may have to take high blood pressure medicine for the rest of your life. If high blood pressure is not treated, it can cause serious problems such as heart failure, blood vessel disease, stroke, or kidney disease.

Swallow the extended-release tablet, extended-release capsule, or tablet whole. Do not open, crush, or chew it. It is best to take the extended-release capsule on an empty stomach.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For chest pain: For oral dosage form (extended-release capsules): Adults—At first, 120 milligrams (mg) once a day in the morning. Your doctor may adjust your dose if needed. Children—Use and dose must be determined by your doctor. For oral dosage form (extended-release tablets): Adults—At first, 180 milligrams (mg) once a day, either in the morning or evening. Your doctor may adjust your dose if needed. Children—Use and dose must be determined by your doctor. For oral dosage form (tablets): Adults—At first, 30 milligrams (mg) four times a day before meals and at bedtime. Your doctor may increase your dose if needed. Children—Use and dose must be determined by your doctor.

For high blood pressure: For oral dosage form (extended-release capsules): Adults—At first, 180 to 240 milligrams (mg) once a day in the morning. Your doctor may adjust your dose if needed. Children—Use and dose must be determined by your doctor. For oral dosage form (extended-release tablets): Adults—At first, 180 to 240 milligrams (mg) once a day, either in the morning or at bedtime. Your doctor may adjust your dose if needed. Children—Use and dose must be determined by your doctor.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of diltiazem can be fatal.

Overdose symptoms may include slow heartbeat, weakness, chest pain, shortness of breath, or fainting.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Angizem CD dosage information

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

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To evaluate the extent to which exercise physiologic characteristics account for the association between lower SES and mortality. The e-vent has seen significant growth over a 3-year period with participation increasing from an average of five participants per session to 50. The purpose of this case report is to describe the use of TAMO therapy in the physical therapy intervention for an infant with congenital muscular torticollis (CMT). Structure of the carbohydrate chain of glycosylated porcine prolactin. Effects of atelectasis on pulmonary surfactant and quasi-static lung mechanics.

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To evaluate in a cohort of women with systemic sclerosis (SSc) the dehydroepiandrosterone sulphate (DHEAS) serum levels and their relationship with disease severity. Thus, the oocytes appear to contain the machinery necessary for performing typical genetic recombination. Thus, subsequent interferon synthesis had to be directed by messenger RNA synthesized before addition of actinomycin D. Considerations on the treatment of chronic suppurated otitis media in students of the Bucharest University Center. Enzymatic synthesis of layered titanium phosphates at low temperature and neutral pH by cell-surface display of silicatein-alpha. This behavior is important in establishing the trend of a generalization of the surmise to describe the terrace-width distribution on vicinal surfaces. Tryptophan hydroxylase-1 gene variants associate with a group of suicidal borderline women. The measurement of the nerve conduction velocity of the dorsal nerve of the penis is a valuable test for assessment of impotence in patients with diabetes mellitus.

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Twenty-three patients underwent multidetector computed tomographic scan (MDCT) of the chest 6 months after surgery to evaluate graft patency. This activity was dose dependent and was evident at various effector/target cell ratios. Infiltration of T cells, monocytes, and enhanced endothelial-leukocyte interactions result in microvascular impairment and altered perfusion. Temperature regulation and cold acclimation in the golden hamster. Continuing large-scale clinical investigations may lead to an expansion of their role in therapy for various cardiovascular diseases. Induction of Cellulolytic and Xylanolytic Enzyme Systems in Streptomyces spp. Clinical research during the past 14 years at the National Institute for Rehabilitation Engineering has shown that many elderly persons with permanent vision, hearing, speech, and mobility handicaps can be helped to be happier and more independent through a multidisciplinary team approach. Suitability of the Cordis Stabilizer marker guide wire for quantitative coronary angiography calibration: an in vitro and in vivo study. Determination of difenidol hydrochloride by capillary electrophoresis with electrochemiluminescence detection. Atrophy with large ventricles, subdural hygromas and mild hydrocephalus may still be difficult to separate.

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Mutations conferring resistance to SCH6, a novel hepatitis C virus NS3/4A protease inhibitor. Whether the activity is a music performance, a friendly round of golf, or a high-level track-and-field competition, the benefits of participation in sports and recreation are numerous both at the individual and at the societal level. It was shown that the presence of lichenase in the hybrid proteins facilitated selection and analysis of the hybrid proteins expression in transgenic organisms. Nanovectors targeted to tissues involved in cardiovascular diseases offer great opportunities to improve cardiovascular treatment through their imaging and drug delivery capabilities. Pathogenesis of cerebral hemorrhages in experimental hypertension in rabbits with particular reference to acute vascular lesions (fibrinoid necrosis) of small arteries and arterioles. Degradation of 4-Chlorobenzoate by Facultatively Alkalophilic Arthrobacter sp. Medicinal chemistry of N-acylhydrazones: new lead-compounds of analgesic, antiinflammatory and antithrombotic drugs.

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Pyruvate dehydrogenase phosphatase1 mRNA expression is divergently and dynamically regulated between rat cerebral cortex, hippocampus and thalamus after traumatic brain injury: a potential biomarker of TBI-induced hyper- and hypo-glycaemia and neuronal vulnerability. Coupling increased hepatic carbohydrate catabolism with its ability to promote beta-oxidation in muscle allows PPARdelta to regulate metabolic homeostasis and enhance insulin action by complementary effects in distinct tissues. JMAR human oral squamous cell carcinoma cells were injected into the tongues of nude mice. Double-stranded RNA in hamster, chick, and mosquito cells infected with Sindbis virus. We carried out a literature search on copepods and Daphnia in ecology and ecotoxicology to compare the recognition given to these two taxa in these respective aceon medication fields. At this time point marked expression of TNF-alpha and IFN-gamma mRNA was observed in the endo- and epi-/perineurium of the proximal stump.

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During the 7-week period, the area under the blood alcohol versus time curve (AUC) increased slightly while the rate zantac 150 mg of ethanol elimination also increased slightly. Elucidation of the exact molecular mechanisms of immune and inflammatory responses caused by Chlamydia infection in human fallopian tubal cells in vitro and understanding how Chlamydia infection affects tubal transport and implantation in animal studies in vivo may explain how Chlamydia trachomatis infection drives inflammation and develops the tubal pathology in women with tubal ectopic pregnancy. Proximal intestinal segments showed a restructuring that resulted in mild hypoplasia of the enteric nerve plexuses in the proximal segments. Nonsurgical treatment methods, such as intralesional corticosteroid injections, systemic calcitonin and interferon have been reported. Two reviewers visually and quantitatively analyzed the images and recorded their findings after reaching a consensus. Nutritional regulation of glycolysis in rainbow trout (Salmo gairdneri R.). Its very uniqueness ensured that medical students, like others in the capital, had no set rules of conduct with which to govern their response to death and destruction on such an unprecedented scale in an urban area. In the future these techniques will allow the identification of as yet unidentified anomalies in cattle such as reciprocal translocations and paracentric inversions. Cold and immobilization stress-induced changes in pain responsiveness and brain Met-enkephalin-like immunoreactivity in the rat.

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Enantioselective total synthesis of (-)-flustramines A, B and (-)-flustramides A, B via domino olefination/isomerization/Claisen rearrangement sequence. Probiotic bacteria are found in the intestines of humans and other mammals where they provide health benefits to the host. Theophylline pharmacokinetics in elderly persons and in patients with bronchial asthma or chronic obstructive bronchitis. In the presence of this estrogen implant, luteal function and pregnancy are maintained after hypophysectomy, performed on day 4 of pregnancy. Zwitterionic character of nucleotides: possible significance in the evolution of nucleic acids. STF was injected to gravid mice on day 13 or on day 18 of gestation. Using DynaMed, primary care clinicians answered more questions and changed clinical decisions more often, without increasing overall search time. Percutaneous umbilical blood sampling, a method that involves ultrasonographically guided needle insertion into the umbilical vein, appears to have an acceptable complication rate. Ultrastructural study of the development of the auditory tympana in the cricket Teleogryllus commodus (Walker).

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ATF5 transcription factor plays an essential role in hematopoietic and glioma cell survival and neuronal cell differentiation. We used event-related fMRI to determine how brain responses to a neutral visual target are influenced by the emotional expression of faces appearing at the same is lipitor brand or generic location during a covert orienting task. This study was done to detect the types of Amp C prevalent in Escherichia coli and Klebsiella pneumoniae by multiplex polymerase chain reaction (PCR). RSA (a mixture of retrograded maltodextrins and branched high molecular weight polymers), which is more resistant than RSB (a retrograded potato starch), increased the rate of fermentation accompanied by a decrease of pH in cecum, colon, and feces. The soldiers consumed a nutritionally adequate diet made from fresh foods (A rations) prepared at the training site.

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Caenorhabditis elegans UNC-83 was shown to localize to the outer nuclear membrane and UNC-84 to the inner nuclear membrane in transfected mammalian cells, suggesting the KASH and SUN protein targeting mechanisms are conserved. The diagnostic possibilities of the basic radio-immunological methods for the determination of thyroid function were studied in 316 healthy subjects and 235 patients with diseases of thyroid gland. She responded to pulsed steroid therapy and anticoagulant with resolution of the complication and UC. A factorial design for optimizing a flow injection analysis system. All patients were then given L-T4 therapy individually to maintain all serum free T3 (FT3), free T4 (FT4), and TSH near or within the respective normal ranges. Surprisingly, results showed that not only is trimethylamine N-oxide able to decrease PrP thermal stability at low pH but it also acts as a strong denaturant at room temperature. One of them, 4-methoxy-N-(3-chloro-7-indazolyl)benzenesulfonamide, was identified as the most potent with an IC(50) of 0.44 microM. Radical neck dissections for squamous carcinomas: pathological findings and their clinical implications with particular reference to transcapsular spread. Colonial morphologies of the Smith diffuse strain of Staphylococcus aureus related to mouse virulence. Here, we present MotifIndexer--a comprehensive strategy for de novo identification of DNA regulatory motifs at a genome level.

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Reversible conformational changes in components of the transcortin--steroid complex. Among physicians who were contacted under both approaches, the proportion of patients for whom they approved contact or provided information was significantly higher when they were notified. Fixed pulse widths were programmed using the measured high voltage shock impedance. A recent consensus conference established criteria for standardization and evaluation of GH assays. The postoperative course was uneventful, and the patient remained free of recurrence, 34 months after the original diagnosis was made, and 29 months after surgical resection.

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