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Antialer (Desloratadine)

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Antialer is loratadine in which the ethoxycarbonyl group attached to the piperidine ring is replaced by hydrogen. Antialer is used to provide symptomatic relieve of allergic symptoms. The major metabolite of loratidine, Antialer is an antihistamine which is used for the symptomatic relief of allergic conditions including rhinitis and chronic urticaria. It does not readily enter the central nervous system, so does not cause drowsiness. It has a role as a H1-receptor antagonist, an anti-allergic agent and a cholinergic antagonist.

Other names for this medication:
Alerdain, Alerta, Allerdain, Allerde, Allerede, Allergesic, Antialer, Biomon, Dazit, Delorta, Descare, Desent, Deslor, Desloranid, Desloratadine, Desloriv, Desnova, Dilora, Lorday, Loreta, Nelora, Neoloridin, Nucope, Otrivin, Reditabs, Rodera, Tastylora, Veromon

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Also known as: Desloratadine


Desloratadine and pseudoephedrine is a combination of two medicines used to treat nasal congestion (stuffy nose), sneezing, and runny nose caused by hay fever.

Desloratadine works by preventing the effects of a substance called histamine, which is produced by the body. Histamine can cause itching, sneezing, runny nose, and watery eyes.

The pseudoephedrine causes narrowing of blood vessels. This leads to clearing of nasal congestion, but it may also cause an increase in blood pressure in patients who have high blood pressure.

This medicine is available only with your doctor's prescription.

Do not give any over-the-counter (OTC) cough and cold medicine to a baby or child under 4 years of age. Using these medicines in very young children might cause serious or possibly life-threatening side effects .


Usual Adult Dose for Allergic Rhinitis:

5 mg orally once a day Uses: -Relief of nasal and non-nasal symptoms of seasonal allergic rhinitis -Relief of nasal and non-nasal symptoms of perennial allergic rhinitis -Symptomatic relief of pruritus, reduction in the number of hives, and size of hives in patients with chronic idiopathic urticaria

Usual Adult Dose for Urticaria:

5 mg orally once a day Uses: -Relief of nasal and non-nasal symptoms of seasonal allergic rhinitis -Relief of nasal and non-nasal symptoms of perennial allergic rhinitis -Symptomatic relief of pruritus, reduction in the number of hives, and size of hives in patients with chronic idiopathic urticaria

Usual Pediatric Dose for Allergic Rhinitis:

6 to 11 months: 1 mg orally once a day 12 months to 5 years: 1.25 mg orally once a day 6 to 11 years: 2.5 mg orally once a day 12 years and older: 5 mg orally once a day Uses: -Patients 6 months and older: Relief of nasal and non-nasal symptoms of perennial allergic rhinitis -Patients 6 months and older: Symptomatic relief of pruritus, reduction in the number of hives, and size of hives in patients with chronic idiopathic urticaria -Patients 2 years and older: Relief of nasal and non-nasal symptoms of seasonal allergic rhinitis

Usual Pediatric Dose for Urticaria:

6 to 11 months: 1 mg orally once a day 12 months to 5 years: 1.25 mg orally once a day 6 to 11 years: 2.5 mg orally once a day 12 years and older: 5 mg orally once a day Uses: -Patients 6 months and older: Relief of nasal and non-nasal symptoms of perennial allergic rhinitis -Patients 6 months and older: Symptomatic relief of pruritus, reduction in the number of hives, and size of hives in patients with chronic idiopathic urticaria -Patients 2 years and older: Relief of nasal and non-nasal symptoms of seasonal allergic rhinitis

Detailed Antialer dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose may cause anxiety, trouble sleeping, headache, vomiting, thirst, muscle weakness, fast or pounding heartbeats, hallucinations, shallow breathing, or a seizure.


Store at room temperature 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children in a container that small children cannot open.

Side effects

The most common side effects associated with Antialer are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not use Antialer-D 12 Hour if you are allergic to desloratadine, loratadine (Claritin), or pseudoephedrine, or if you have:

narrow-angle glaucoma; severe coronary artery disease (clogged arteries); uncontrolled high blood pressure; or bladder obstruction or other urination problems.

Do not use Antialer-D 12 Hour if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.

Tell your doctor if you have ever had:

kidney disease; glaucoma; heart disease or high blood pressure; a seizure (in you or a family member); diabetes; thyroid disorder; or an enlarged prostate.

Antialer-D 12 Hour should not be given to a child younger than 12 years old.

It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

You should not breast feed while using desloratadine and pseudoephedrine.

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