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Anxofit (Alprazolam)

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Alprazolam, available under the trade name Xanax, is a potent, short-acting benzodiazepine anxiolytic—a minor tranquilizer. It is commonly used for the treatment of anxiety disorders, especially of panic disorder, but also in the treatment of generalized anxiety disorder (GAD) or social anxiety disorder. It was the 12th most prescribed medicine in the United States in 2010. Anxofit, like other benzodiazepines, binds to specific sites on the GABAA receptor. It possesses anxiolytic, sedative, hypnotic, skeletal muscle relaxant, anticonvulsant, amnestic, and antidepressant properties. Anxofit is available for oral administration as compressed tablets (CT) and extended-release capsules (XR).

Other names for this medication:
Aldip, Alfix, Alfresh, Alpaz, Alprosym, Alprozam, Alrif, Alzex, Alzin, Alzolite, Alzoset, Ansilumirm, Anxicalm, Anxit, Anzocalm, Balmusa, Belfa, Besquil, Betapax, Calmtec, Cooltime, Depser, Depsolam, Emlol, Erazol, Fludep, Golprax, Himzolam, Imprax, Mebrin, Nitril, Nokzok, Oclam, Poize, Restam, Rivcam, Sanprazole, Serex, Somnirest, Tranisol, Welnorm, Wycalm, Xerodep, Zeprax, Zocam, Zolran, Zolyde, Zopax, Zorest

Similar Products:
Diovan, Cenforce, Aricept, Mircette, Aldara

Also known as: Alprazolam


{name} XR (alprazolam) is in a group of drugs called benzodiazepines (ben-zoe-dye-AZE-eh-peens). Alprazolam affects chemicals in the brain that may become unbalanced and cause anxiety.

{name} XR is used to treat anxiety disorders, panic disorders, and anxiety caused by depression.

{name} XR may also be used for other purposes not listed in this medication guide.


This section provides information on the proper use of a number of products that contain alprazolam. It may not be specific to Anxofit. Please read with care.

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. If too much of this medicine is used for a long time, it may become habit-forming (causing mental or physical dependence) or cause an overdose.

This medicine should come with a Medication Guide. Read and follow the instructions carefully. Ask your doctor if you have any questions.

Swallow the extended-release tablet or tablet whole with a full glass of water. Do not break, crush, or chew it.

If you are using the orally disintegrating tablet, make sure your hands are dry before you handle the tablet. Do not remove the tablets from the bottle until you are ready to take it. Place the tablet immediately on the top of your tongue. It should melt quickly and be swallowed with saliva.

If you are using the oral liquid, measure the dose with a marked measuring spoon, oral syringe, or medicine cup.

Do not eat grapefruit or drink grapefruit juice while you are using this medicine.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For anxiety: For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.25 to 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 4 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For panic disorder: For oral dosage form (extended-release tablets): Adults—At first, 0.5 to 1 milligram (mg) taken in the morning once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.5 mg taken in the morning once a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of alprazolam can be fatal.

Overdose symptoms may include extreme drowsiness, confusion, muscle weakness, loss of balance or coordination, feeling light-headed, and fainting.


Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details.

Side effects

The most common side effects associated with Anxofit are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Studies in women breastfeeding have demonstrated harmful infant effects. An alternative to this medication should be prescribed or you should stop breastfeeding while using this medicine.

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During 48 hours after injury, estimation of serum levels of pNF-H, NSE, and GFAP, combined with neurological testing, could predict the presence of SCI and severity prior to spinal computed tomography and surgical or conservative interventions. A total of 155 guidelines from 40 medical organizations met inclusion criteria and are represented in our compendium. The combination of hypercholesterolemia and ionizing radiation may serve as a useful experimental model for further studies in various animal species on why and how plaques originate, develop or regress and how they could possibly be prevented. Epigastric discomfort and scalp tingling have been documented especially after intravenous administration. Asymmetry of dopamine D2 receptor binding predicts sensitivity to reward versus punishment. The target of rapamycin (TOR) kinase integrates nutritional and stress signals to coordinately control cell growth in all eukaryotes. Identification of candidate genes JcARF19 and JcIAA9 associated with seed size traits in Jatropha.

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Autologous bone marrow transplantation in acute leukemia and lymphoma following ex vivo treatment with monoclonal antibodies and complement. Sustained heterozygosity across a self-incompatibility locus in an inbred ascidian. This dose from different diagnostic procedures provides information that can be used to establish national reference levels. Knowledge in why, where, and when TDI appears is therefore essential for dental personnel who will work to reduce TDI. The changes of xCT expression in both Acb and whole brain following ethanol dependence and withdrawal indicate that xCT might represent a novel therapeutic target for the treatment of ethanol addiction. Recovery from stroke is dependent on axonal sprouting and reconnection that occurs during a third degenerative/regenerative phase. To determine the efficacy, stability, and predictability of refractive surgery for hyperopia using four different procedures: photorefractive keratectomy (PRK), laser in situ keratomileusis (LASIK), implantation of a phakic intraocular lens (PIOL), and removing the transparent lens with IOL implantation.

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The expression of a membrane-anchored gp41-derived peptide (M87) has been shown to confer protection from infection through human immunodeficiency virus type 1 (HIV-1) (Hildinger et al., J. The UK has a rapidly ageing population with increasing healthcare needs. This analysis reveals an asymptotic link between Laguerre-Gauss beams and one-dimensional Hermite-Gauss beams in the limit of high azimuthal orders. Here we investigate whether Shox2 and Hox genes function together during mouse limb development by modulating their relative dosage and examining the limb for nonadditive effects on growth. Relative deficits in verbal knowledge and verbal memory may continue to increase after deficits in other domains have stabilized. Psychological barriers to Internet usage among older adults in the UK. We have determined by immunohistochemistry the expression of matriptase and HAI-1 in 54 epithelial ovarian cancers.

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The results indicate that both surgical techniques are effective procedures in the treatment of shoulder impingement syndrome, and the type of bone resection does not influence the clinical outcome. As a result, the vital role of essential surgical care and safe anesthesia in low-income and middle-income countries is gaining increasing attention. Arbuscular mycorrhizal fungi (Glomeromycota) harbour ancient fungal tubulin genes that resemble those of the chytrids (Chytridiomycota). Principles of nucleation of H3K27 methylation during embryonic development. We performed a survey of neglected tropical diseases experts to elicit their opinions on the role of mass drug administrations for the elimination of these infections. In contrast, after FR, ObRe mRNA expression decreased, whereas ObRa mRNA expression further increased compared with 8- and 24-month-old rats fed AL. In this systematic review we have undertaken a comprehensive analysis to assess the effectiveness of anti-oestrogen therapy in terms of ability to induce partial or complete regression of DTs. The advent of targeted therapy in RCC does not eliminate the potential utility of immunotherapy but rather requires a rational refinement of this approach through improvements in patient selection and combination therapy that may increase the cure rate for patients with this disease. The goal is to provide the clinician neurosurgeon with the knowledge and tools needed to appraise published economic evaluations and to direct high-quality health economic evaluations.

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An open reading frame in intron seven of the sea urchin DNA-methyltransferase gene codes for a functional AP1 endonuclease. RAPD profiles of the faecal isolate were identical to that of strains isolated from a commercial product. Among groups of antihypertensive agents angiotensin converting enzyme inhibitors, angiotensin receptor blockers, calcium antagonists, beta-blockers, and diuretics have proven renoprotective properties. Validation of echocardiographic methods for assessing left ventricular dysfunction in rats with myocardial infarction. eggs contained hexoses, ketoses, 6-deoxyhexoses, heptoses and uronic acids with hexoses, ketoses, and 6-deoxysugars occurring free and in bound form. Then caspase-3 activity was activated, followed by DNA fragmentation.

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The inhibitory effect on HBsAg secretion was footed using aqueous extracts of Agrimonia eupatoria at four different temperatures (37 degrees C 45 degrees C, 55 degrees C and 60 degrees C), and the extract prepared at 60 degrees C was found to have the greatest effect. An in vitro investigation of genetic susceptibility to cancer in diploid fibroblasts from retinoblastoma patients. The inefficient formation of a charge-separated state, both in solution and in the solid state, translates into a poor photovoltaic performance of dyads 2 b-4 b if compared to that of dyad 1 b, in which photoinduced electron transfer is operative in the solid state. By adopting a randomization grouping, parallel control, and prospective study, 73 T2DM patients of QYDPSIOS were assigned to two groups by random digit table, the Pioglitazone Tablet group (36 cases, as the control) and the JTXZC group (37 cases). Excess recurrent cardiac events in rheumatoid arthritis patients with acute coronary syndrome. Aroclor 1254-treatment caused a 4.2-fold induction of GSH S-transferase in NFS/NCR but only a 1.4-fold increase in AKR/NCR mice. Photosynthetic light reactions--an adjustable hub in basic production and plant immunity signaling. However, estimated rates for these countries still exhibit wide discrepancies related to the methods used.

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Ciprofloxacin appeared to be the most potent inhibitor of colony formation among the antimicrobial agents tested. High level of dexterity: differential contributions of frontal and parietal areas. Monitoring of tick-borne encephalitis virus populations and etiological structure of morbidity over 60 years. Alternatively, retrograde extra-articular drilling avoids drilling the cartilage while ensuring adequate channels for revascularization and healing. Bioanalytical methods for the metalloproteomics study of bovine longissimus thoracis muscle tissue with different grades of meat tenderness in the Nellore breed (Bos indicus). At a major university medical center, untreated semen was compared with semen treated with anti-ASC polyclonal antibody. The immunotolerance mechanism of the third-party bone marrow-derived mesenchymal stem cells in the allogeneic transplantation might be associated with its effect on the proliferation of Treg cells and increasing expression of TGF-beta and IL-10, decreasing expression of IFN-gamma. Possible implications for medical practice and clinical trial research will be discussed in the article. The different extraction methods did not affect the quality of results, while the commercial real-time kit cannot be used.

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Le Fort fractures are a part of the facial fracture spectrum, sustained from significant forces of impact to the midface. In muscles sectioned longitudinally, points of rhodanese staining occurred in linear arrays along the lengths of the muscle fiber corresponding to the location of mitochondria within the fiber. Surface expression of CD25, CD28, CD40, CD54, CD80, CD86 and CTLA-4 was evaluated on CD3, CD4, CD8, CD14 and CD19 PBMC subpopulations by three-colour flow cytometry. 2014 Williams Harvey Lecture: importance of coronary vasomotion abnormalities-from bench to bedside. A great deal of research has been performed during recent years and guidelines for the management of avulsions have been published. Yki/YAP, Sd/TEAD and Hth/MEIS control tissue specification in the Drosophila eye disc epithelium.

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This is a case-report of a male infant with typical signs of Cornelia de Lange syndrome. This study was conducted to evaluate blood pressure control glucose homeostasis, and the plasma lipid profile in patients with type 2 diabetes mellitus and mild hypertension during 12 months of treatment with the ARB telmisartan or nifedipine gastrointestinal therapeutic system (GITS). Reconstruction results were compared with target EP values in both simulations and phantom experiments. The dynamic properties of chromatin play essential roles in regulating genomic DNA functions, such as DNA replication, recombination, repair, and transcription. In addition to reductions in annual relapse rates and other measures of clinical disability, the disease-modifying drugs appear to reduce MRI measures of disease activity. One of the fundamental lines followed by Neuropsychology today focuses on rehabilitation processes and their effectiveness. Familial body concepts and illness attributions in primary headache in childhood and adolescence. Annexin 1 was detected by immunoblotting, in tissue homogenates and supernatants of colonic biopsies incubated in culture media, and in luminal colonic perfusates of UC patients.

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Over the last thirty years such genetic screens have been used to elucidate the cell cycle, secretory pathway, and many more highly conserved aspects of eukaryotic cell biology (1-5). These results indicate that multiple factors contribute to the placebo effect, including suggestibility, expectancy and conditioning, and that the judgement of placebo analgesia is critically determined by whether pain relief is assessed concurrently or bactrim dosing hemodialysis after treatment. Concurrently, its neuromuscular synapses enlarge in area, become perforated, and acquire more active sites of transmitter release. Effects of carvedilol on the hemodynamics and its tolerance in elderly patients. A comment on the role of magnesium in the control of muscle glycogen synthetase kinase. Pseudomonas aeruginosa regulates the production of many exoproteins and secondary metabolites via a hierarchical quorum-sensing cascade through LasR and RhlR and their cognate signal molecules N-(3-oxododecanoyl)-L-homoserine lactone (3O-C12-HSL) and N-(butanoyl)-L-homoserine lactone (C4-HSL). We aimed to evaluate the effect of vitamin D analogue, Alfacalcidol, on MS-related fatigue.

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Nervous tissue samples were collected from infected animals for immunohistochemistry and molecular biology analysis. The PG-induced modulation disappeared after chemical sympathectomy, suggesting that the PG-induced modulation of pressor response is regulated by the sympathetic nervous system. MM was modelled on publicly available information from the PARTNER-B study. Multifaceted genome control by Set1 Dependent and Independent of H3K4 methylation and the Set1C/COMPASS complex. The who, what, why, and how-to guide for circumferential pulmonary vein ablation. It is concluded that YM-11170 is a competitive antagonist of dimaprit-induced gastric secretion in vivo and that the activity of the H2-antagonists in blocking gastric H2-receptors may reflect their inhibitory effect on the acid response to pentagastrin and methacholine. Two designed peptides that formed higher-order structures suggest how future design protocols could be improved. Self-concept structure and borderline personality disorder: evidence for negative compartmentalization.

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Secondary angiographic efficacy endpoints were binary restenosis at 8 months, in-stent minimum luminal diameter (MLD), and late loss. The HPLC fractions were tested in several EIAs for glucocorticoid metabolites. sinensis (CsHK), the first key regulatory enzyme of the glycolytic pathway, was characterized in this study. In cardiomyocytes, the EDG1 receptor is likely to be co-expressed with EDG3 and EDG5, although EDG1 exhibits the most prominent expression pattern. The majority of the congenital anomalies of middle ear are solitary and a non-hereditary.

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Oral lichen planus in childhood seems to occur preferentially in those of Asian race. In vitro protection of cerebral mitochondrial function by E-resveratrol in anoxia followed by re-oxygenation. One effect of this may be that the learning of behavioural sequences is delayed, and that only short behavioural sequences are acquired in ADHD. It affects at any age and is equally present in both sexes with highest incidence in second decade of life. Moderate alcohol consumption and the risk of cardiovascular disease. A conclusive diagnosis of Pneumocystis carinii pneumonia in a smoldering ATL patient was made on these grounds. To evaluate the cost-effectiveness of different drug therapies for chronic hepatitis B in adult patients. Menstrual cycle interval, intensity and duration of bleeding, premenstrual symptoms, dysmenorrhea, dyspareunia, noncyclic pelvic pain and degree of sexual satisfaction were assessed in this questionnaire.

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The levels of SAH-hydrolase activity were also found to undergo a sharp decrease with red cell ageing. Anastomotic complications after esophagectomy continue to be a burden jeopardizing biaxin dosage pediatric the quality of life and of swallowing. Two-dimensional (2D) nanostructure patterns have extensive applications in photonic devices, nanoelectronics, electrochemical devices, biosensors, catalysts and high-density magnetic recording devices. Manipulations (neurological or behavioral) that either reduced the level of freezing or retarded its development promoted startle response decrements. Draft Genome Sequence of Lactobacillus crispatus EM-LC1, an Isolate with Antimicrobial Activity Cultured from an Elderly Subject. Characteristics and treatment preferences of people with symptoms of posttraumatic stress disorder: an internet survey. We included randomised controlled trials examining chemotherapy including at least two cycles of escalated BEACOPP regimens compared to chemotherapy including at least four cycles of ABVD regimens as first-line treatment for patients with early unfavourable stage or advanced stage HL. It is argued that a range of communicative formats serve to produce the activities associated with police murder investigations in a way that serves to legitimate the police function to both members of the public and police officers alike. Development, reliability, and validity of a novel Epidermolysis Bullosa Disease Activity and Scarring Index (EBDASI). Increased patient throughput and patient acuity resulting from the introduction of prospective funding mechanisms, such as Case Mix (based on the Diagnosis Related Groups) for in-patient acute care, raised serious concerns about compromising quality of care delivered to patients.

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The technique of incisionless otoplasty used in this study was well tolerated and effective in both pediatric and adult patients, producing favorable outcomes with minimal complications. Surgical results of proximal gastrectomy for early-stage gastric cancer: jejunal interposition and gastric tube reconstruction. Non-invasive H pylori testing should be the preferred mode of investigation. Treatment of mid-late stage NSCLC using sodium cantharidinate/vitamin B6/GP regimen in clinic. Two patients who were lepromin negative at diagnosis were retested after about 1 year of anti-retroviral treatment, and found to be positive. Here, we experimentally study the spring phenology of the orange tip butterfly, Anthocharis cardamines, by analysing post-winter pupal development in three populations along a latitudinal cline in each of Sweden and the United Kingdom. The concentrations of all measured iodine species vary noticeably above 1000 m but only minor latitudinal changes occur below 1000 m and slight vertical alterations can be observed below 2400 m. In total, 25 interviews were carried out over a period of 5 years. Isolations and further studies of Venezuelan and eastern equine encephalitis, Una, Itaqui, and Moju viruses. The ex rulide antibiotic dose vivo technique may be less applicable in rectal cancer and false negative results may occur.

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According to our study, posterior globe flattening, intraocular protrusion of the optic nerve, horizontal nerve sheath tortuosity, optic nerve sheath distension, and decreased pituitary gland size are reliable neuroradiological diagnostic markers for pediatric pseudotumor cerebri. Significant progress has been made during the past decade in corrective gene therapy of the skin. Road mobility and the risk of road traffic accident as a driver. The effects of the pyrethroids flucythrinate, cyfluthrin, bioallethrin and resmethrin on metabolic cooperation between V79 cells were investigated. Assay for cyclo-, seco- and pentobarbital by multiple ion detection: kinetics after a single dose.

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Compounding the problem is the repetitive nature of lateral ankle sprains, referred to as functional (FAI) or chronic (CAI) ankle instability. Sensory input regulates spatial and subtype-specific patterns of neuronal turnover in the adult olfactory bulb. Novel adeno-associated viruses derived from pig tissues transduce most major organs in mice. Globally, one-quarter of a million people die from peptic ulcer disease each year. Long-term treatment with antipsychotics: new research strengthens the information about the risk of brain atrophy.

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