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Aprical (Nifedipine)

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Aprical is a drug that performs by relaxing the muscles inside the heart and blood vessels in order to enable easier blood flow. This enables the heart to have an easier time pumping blood. The active ingredient is nifedipine and it a part of a class of drugs called calcium channel blockers. The primary use of this medication is to help stop chest pain (angina) and help treat high blood pressure problems (hypertension). In addition to this it can also be used in order to heighten the supply of oxygen and blood to the heart and help with a specific blood circulation condition called Raynaud’s phenomenon.

Other names for this medication:
Aprical, Atanaal, Cardicon, Cardiosol, Cardipin, Corotrend, Depicor, Fenidina, Myogard, Nelapine, Nicardia, Nidilat, Nifecap, Nifecard, Nifedel, Nifedipine, Nifelong, Nifensar, Nifeslow, Nirena, Oxcord, Sepamit, Siopelmin, Tensopin, Tredalat

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Also known as: Nifedipine


Nifedipine is used alone or together with other medicines to treat severe chest pain (angina) or high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled.

Nifedipine is a calcium channel blocker. It works by affecting the movement of calcium into the cells of the heart and blood vessels. As a result, nifedipine relaxes blood vessels and increases the supply of blood and oxygen to the heart while reducing its workload.

This medicine is available only with your doctor's prescription.


Aprical should be taken orally with or without food. It is better to take Aprical at the same time every day. Take on an empty stomach. Avoid grapefruit juice during treatment with Aprical. If you want to achieve most effective results do not stop taking Aprical suddenly.


If you overdose Aprical and you don't feel good you should visit your doctor or health care provider immediately.


Store at room temperature between 15 and 25 degrees C (59 and 77 degrees F) away from moisture and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Aprical are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Appropriate studies have not been performed on the relationship of age to the effects of nifedipine in the pediatric population. Safety and efficacy have not been established.

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The effect of flexion angle on the macro and microscopic appearance of the rupture surface of the ACL of rabbits. Much of the knowledge derived from the huge number of discoveries in molecular biology research over the past five decades and the genome project has the potential to be of immense benefit world-wide. Beyond the sound of one hand clapping: experiences in six countries using health equity research in policy. Electrophysiologic effects and efficacy of intravenous propafenone in terminating atrioventricular reentrant tachycardia in children. The biopsy showed deposition of yellow-brown globules in the dermis. Impaired retention of technetium-99m tetrofosmin in hypertrophic cardiomyopathy. For those who did not choose to wear lenses, the reason was asked. When mice were treated with ultraviolet (UV) radiation before immunization with the skin sensitizers, trinitro-chlorobenzene or dinitrofluorobenzene, they showed greatly depressed levels of priming for a secondary in vitro cytotoxic response against haptenated cells. The transformed WI-38 cells which are growing steadily without showing aging phenomena at the present time showed epithelial-like morphology, abnormal karyology, B-type isoenzyme pattern of glucose-6-phosphate dehydrogenase (G6PD), and produced sarcomas when transplanted into cheek pouches of hamsters treated with anti-hamster thymocyte serum.

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Glucose-6-phosphate dehydrogenase and phosphofructokinase were isolated from hemolysate and investigated. Unusual behavior of membrane somatic angiotensin-converting enzyme in a reversed micelle system. Analytic studies of nitrogen for optimizing the nutrition of very premature infants by supplementation with breast milk. Transabdominal embryofetoscopy was performed at 13 weeks of gestation. On the other hand, laparoscopic gastrectomy with lymph node dissection, such as laparoscopy-assisted distal gastrectomy, is widely accepted for the treatment of EGC with the risk of lymph node metastasis. The second glucose tolerance test performed on Day 18 yielded similar results. C-tubes were used as substitutes for posterior dental anchorage during upper anterior retraction. Phylogenetic study of Rickettsia species using sequences of the autotransporter protein-encoding gene sca2.

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We conclude that more data is required to understand the spectrum of PRES and its management in SLE patients. Sociometry is presented as an alternative way of measuring role taking, specifically, an alternative to an often used projective measure, the Role-Taking Task (RTT). From these observations we speculated that the threshold of taste sensation is increased in rats fed a low- panadol australia medicine protein diet. Significance of frozen section diagnosis for the management of laryngeal tumors. However, the emerging concept of cooperative hormone action opens new possibilities for a better understanding of the complex interactions of all phytohormones and their possible synergistic effects and involvement in the gravitropic bending process. Bidentate coordination of pyrazolate in low-coordinate iron(II) and nickel(II) complexes. A new TFSI- anion disordering mode has been discovered in a supercooled plastic crystalline phase of Et4NTFSI, which may, in part, account for the low melting points of TFSI- salts with organic cations, thereby forming ionic liquids, and the intriguing properties of LiTFSI for lithium battery applications. Many have done a good job of tracking and enabling employers to appreciate the impact they have had on business performance, but few have done the same for the health and quality-of-life they deliver to consumers.

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Little is known about the role of xenobiotic-metabolizing gene variants as risk factors for small-for-gestational-age (SGA) births or as modifiers for the effects of exposures such as maternal smoking. The quality of the product is documented using 3 independent assay criteria. Surgeons may face a dilemma in which their obligations to their patients and their obligations to others or society may conflict. To describe the epidemiological aspects of childhood tuberculosis (TB) in a Brazilian reference hospital. The structure provides insight into the cleocin antibiotic and alcohol organization of the cytoplasmic domains within the ClC family and establishes a framework for guiding future investigations on regulatory mechanisms. Specificity as well as reproducibility of MMTC is demonstrated and a novel MMTC-based function to improve visual discrimination of subpopulations is introduced. The high number of 14 integrally bound lipids reflects the structural and functional importance of these molecules for flexibility within and assembly of photosystem II. The case of uniformly distributed points is first studied as a benchmark. Focus on the family as a factor in differential treatment outcome.

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A large cervico-mediastinal tracheal defect in a 72-year-old man as a result of surgery for thyroid carcinoma with tracheal invasion and mediastinal lymph node metastasis was reconstructed using a pectoralis major myocutaneous flap and free costal cartilage grafts. Carcinogenic activation of benzo(a)pyrene by iodine and ferric chloride in the respiratory tract of Syrian golden hamsters. It is concluded that Vicryl and Dexon sutures of suitable USP size can secure the wound until the time when the suture is superfluous. We describe a case of renal oncocytoma with the unusual gross appearance of a cystic tumor. Educational programs are needed to maintain vasotec drug class the low-risk status of Southwestern Hispanics for cigarette-related diseases. The immediate and late follow-up results of their application are satisfactory. The influence on this process of the basic N-terminal part of the protein and of the previously identified hydrophobic loop has also been investigated. Percutaneous balloon valvuloplasty for congenital pulmonary valve stenosis.

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Effects of azathioprine on the human mixed lymphocyte reaction (MLR). Motion sickness susceptibility: a retrospective comparison of laboratory tests. The aim of this work is to present prostate cancer highlights of the 2005 AUA annual meeting, and in particular the main subjects of news and innovations that are supposed to modify urological clinical practice. Morphological modifications of the mast cells of the vessel wall in the course of provoked venous stasis. In case of additional disease of the pleura, mediastinum and lung parenchyma, further measures may be necessary: especially in chronic obstructive lung disease ventilation perfusion ratio and outwash of xenon might be helpful.

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The hydrolytic activity of urokinase (plasminogen activator from urine) on acetyl-glycyl-L-lysine methylester acetate (Ac-gly-lys-OMeAc) was inhibited by antithrombin III in a slow time-dependent manner. In this study we assessed the contributions of regional and cellular differences in the distribution of the IL-13R components to the physiological regulation of smooth muscle function in wild-type mice and mice deficient in STAT6 or IL-13Ralpha2. The detection of marrow and/or blood host cells suggests graft rejection, relapse of the underlying disease, or a state of stable mixed chimerism. Mockery through caricature: a variant of introjection utilized by a masochistic woman. This cell line provides a unique in vitro hepatoma cell system for the investigation of structural and functional properties of HCV NS proteins. Current judgments: Obligatory protection of medical competition while leasing medical offices. The expression products were analyzed through SDS-PAGE followed by Coomassie blue staining. To describe the prevalence and risk factors of diabetic retinopathy in a multi-ethnic US population of whites, blacks, hispanics, and chinese. Among both healthy adults and patients, active and avoidance coping were positively associated with negative life events. Part 1: contribution of the amino group and the uracil moiety upon the inhibition of MraY.

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Whiplash: a case of regretting being responsible for naming a condition. After being weighted according to complex sampling scheme and post-stratification, the sample was used to estimate the prevalence of hypertension by age, gender, urban and rural areas, and geographic locations. The titres were compared to that obtained by conventional assays. These changes show that exposure of pseudoglandular lungs to hyperoxia modulates the lung architecture to resemble saccular lungs. A questionnaire on the management of radiologically placed drains was sent to all radiology departments on a Royal College of Radiologists database. oryzae alpha-amylase gene (creA) was deleted, no significant decrease in the specific rate of alpha-amylase formation was observed. Improved ethanol yield and reduced Minimum Ethanol Selling Price (MESP) by modifying low severity dilute acid pretreatment with deacetylation and mechanical refining: 1) Experimental. Given the potential for laboratory-associated severe acute respiratory syndrome-associated coronavirus (SARS-CoV) infections, we must know which cell lines are susceptible to the virus.

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Combining therapeutics with single-agent activity has improved treatment for patients with many malignancies. By flow cytometry, three OB cell lines all were found to express ligands for T-cell co-stimulation. However, the mechanism of light absorption by a chromophore does not explain many of the experimental observations and therefore the primary mechanism for cellular light responses remains unproven. Facile shape control of Co(3)O(4) and the effect of the crystal plane on electrochemical performance. Both patients had CCC and phacoemulsification and confirmed in-the-bag acrylic IOL implantation in the second eye months after surgery in the first eye. 7 amelanotic/hypomelanotic melanomas in 6 patients were analyzed in order to define their dermatoscopic findings using standard pattern analysis. Long-term prediction of mortality in elderly persons by dobutamine stress echocardiography. Phosphorylation of serine 144 in cells is also induced by hyperosmotic stress, which activates PKCzeta and regulates its interaction with caspase 9, but not by growth factors, phorbol ester, or other cellular stresses. We report successful treatment of a total hip replacement infected with this rare organism by a two-stage revision and synergistic combination antifungal therapy amiloride 5 mg tablets accord with Amphotericin B and 5-Flucytosine. The analysis of intracellular cAMP levels showed that gpr4 mutants still respond to glucose but not to certain amino acids, such as methionine.

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Modulation of pain-induced neuromuscular trunk responses by pain expectations: a single group study. The project was financed by the European Commission in the 5th Framework Programme and involved agronomists, biologists, analytical chemists, organic chemists, environmental chemists, ecotoxicologists, and modelers. She underwent urgent aortic valve replacement and, despite implementation of known fetal-protection strategies, fetal demise occurred. Unusual posterior reversible encephalopathy syndrome in a case of influenza A/H1N1 infection. Pom1p is present in a large protein complex and requires its non-catalytic domain to localize to the cell periphery and its kinase activity to localize to cell ends. After removal of a 300-g adenocarcinoma, gynecomastia regressed and essentially normal hormone levels were restored.

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Tips and strategies for problem solving during each step are included. Based on the findings from this exploratory study, participation in a domestic or international medical mission trip as a student volunteer or APPE student appears to have a positive impact on some of the beliefs and perceptions of GSOP students. Calcipenic osteopathies from the viewpoint of the rheumatologist. gondii serum was used to confirm the expression of GST-ROP17 and analyze its antigenic properties. It increases practical usefulness by eliminating unimportant factors in the screening step. Development of a silver nanoparticle-based method for the antioxidant capacity measurement of polyphenols. Glucagon immunoassay using polyethylene glycol to precipitate antibody-bound hormone. It has a great implication to developing any effective treatment or prevention strategies for such transmissions. To evaluate the phytochemical constituents and the aphrodisiac potential of the aqueous extract of Fadogia agrestis (Rubiaceae) stem in male albino rats.

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We conclude that single-unit biventricular ICD implantation is feasible for pacing and ventricular tachyarrhythmia control in patients with underlying atrial fibrillation. Folate, vitamin B6, vitamin B12, and vitamin B2 intake, genetic polymorphisms of related enzymes, and risk of colorectal cancer in a hospital-based case-control study in Japan. The other anaesthetic agents significantly increased only the contralateral reflex thresholds. Pathologic evaluation found the tumor to arise from the endocervix and to be of predominant signet ring cell morphology. Consequently, oral glucose tolerance test results in a pregnancy complicated by gestational diabetes mellitus with a fetus that already has hyperinsulinemia may erroneously be considered normal. Evaluation of clinical signs and causes of lower urinary tract disease in European cats. Our results show significant increment in the number of ovarian follicles expressing the gap junction subunit Cx43 after in vivo rGH treatment.

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