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Arapres (Losartan)

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Arapres is used to treat patients with chronic heart failure when therapy with specific medicines called angiotensin-converting-enzyme inhibitors (ACE inhibitors, medicine used to lower high blood pressure) is not considered suitable by your doctor. If your heart failure has been stabilised with an ACE inhibitor you should not be switched to Arapres.

Other names for this medication:
Aratan, Araten, Faxiven, Forzaar, Insaar, Lohyp, Loortan, Lopress, Losacar, Losap, Losarb, Losartanum, Maxartan, Niten, Ostan, Psycholanz, Resilo, Sanipresin, Sarilen, Sarlo, Sortal, Sortiva, Tensiohess, Tiasar, Tozaar, Zaart

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Also known as: Losartan


{name} (losartan) belongs to a group of drugs called angiotensin II receptor antagonists (sometimes called ARB blockers). It keeps blood vessels from narrowing, which lowers blood pressure and improves blood flow.

{name} is used to treat high blood pressure (hypertension) in adults and children who are at least 6 years old. It is also used to lower the risk of stroke in certain people with heart disease.

{name} is also used to slow long-term kidney damage in people with type 2 diabetes who also have high blood pressure.


Usual Adult Dose for Diabetic Nephropathy:

Initial dose: 50 mg orally once a day Maximum dose: 100 mg orally once a day Comments: -If hypertensive patients with left ventricular hypertrophy or type 2 diabetic nephropathy patients require titration from initial dose, increase to 100 mg orally once a day. -Antihypertension is substantially present within 1 week but in some studies the maximal effect occurred in 3 to 6 weeks. Uses: -Treatment of hypertension. -To reduce the risk of stroke in patients with hypertension and left ventricular hypertrophy. -Treatment of diabetic nephropathy with an elevated serum creatinine and proteinuria (urinary albumin to creatinine ratio 300 mg/g or greater) in patients with type 2 diabetes and a history of hypertension.

Usual Adult Dose for Hypertension:

Initial dose: 50 mg orally once a day Maximum dose: 100 mg orally once a day Comments: -If hypertensive patients with left ventricular hypertrophy or type 2 diabetic nephropathy patients require titration from initial dose, increase to 100 mg orally once a day. -Antihypertension is substantially present within 1 week but in some studies the maximal effect occurred in 3 to 6 weeks. Uses: -Treatment of hypertension. -To reduce the risk of stroke in patients with hypertension and left ventricular hypertrophy. -Treatment of diabetic nephropathy with an elevated serum creatinine and proteinuria (urinary albumin to creatinine ratio 300 mg/g or greater) in patients with type 2 diabetes and a history of hypertension.

Usual Pediatric Dose for Hypertension:

6 Years or Older: Initial dose: 0.7 mg/kg orally once a day (up to 50 mg total) Comments: -May be given as a tablet or suspension. -Doses above 1.4 mg/kg (or 100 mg) daily have not been studied in pediatric patients.

Detailed Arapres dosage information


If you overdose Arapres and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Arapres overdosage: fainting, feeling lightheaded, rapid heartbeat.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children in a container that small children cannot open.

Side effects

The most common side effects associated with Arapres are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Changes in renal function including acute renal failure can be caused by drugs that inhibit the reninangiotensin system and by diuretics. Patients whose renal function may depend in part on the activity of the renin-angiotensin system (e.g., patients with renal artery stenosis, chronic kidney disease, severe congestive heart failure, or volume depletion) may be at particular risk of developing acute renal failure on COZAAR. Monitor renal function periodically in these patients. Consider withholding or discontinuing therapy in patients who develop a clinically significant decrease in renal function on Arapres.

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Dental caries in the primary (dmft) and permanent (DMFT) dentitions at baseline are goods indicators of subsequent caries development in this group of children in a medium income country. Serum and kidney beta-N-acetyl-D-glucosaminidase in vasectomized rhesus monkeys. Ultrastructure of the palpal bulb sensilla of the black fly Simulium arcticum (Diptera: Simuliidae). A peak of glutamine synthetase activity was seen during fermentation for production of the antibiotic thienamycin. Several themes emerged in the literature regarding culture, language, health beliefs and health care access among Pacific Islander women. This research investigated the regulation of LiP and MnP production by Mn(II). Microglial cultures obtained from rat cerebral cortex were found to express the excitatory amino acid transporter GLT-1, but not neurontin 600mg tablets GLAST, and this expression was increased by 1 ng/ml lipopolysaccharide after 12 h of stimulation.

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