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Aratan (Losartan)
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Aratan

Aratan and associated names, 12,5 mg, 25mg, 50 mg, 100 mg, film-coated tablets is an orally active angiotensin II (Ang- II) receptor antagonist, Aratan, acting on the AT1 receptor subtype, thus blocking the effect of Ang-II in the renin angiotensin system (RAS) cascade. Aratan is indicated for the treatment of hypertension.

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Also known as: Losartan

Description

{name} (losartan) belongs to a group of drugs called angiotensin II receptor antagonists (sometimes called ARB blockers). It keeps blood vessels from narrowing, which lowers blood pressure and improves blood flow.

{name} is used to treat high blood pressure (hypertension) in adults and children who are at least 6 years old. It is also used to lower the risk of stroke in certain people with heart disease.

{name} is also used to slow long-term kidney damage in people with type 2 diabetes who also have high blood pressure.

Dosage

Take Aratan tablets orally with or without food. Do not crush or chew it. Take Aratan once or twice a day at the same time. If you want to achieve most effective results do not stop taking Aratan suddenly.

Overdose

If you overdose Aratan and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Aratan overdosage: fainting, feeling lightheaded, rapid heartbeat.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children in a container that small children cannot open.

Side effects

The most common side effects associated with Aratan are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Use of drugs that act on the renin-angiotensin system during the second and third trimesters of pregnancy reduces fetal renal function and increases fetal and neonatal morbidity and death. Resulting oligohydramnios can be associated with fetal lung hypoplasia and skeletal deformations. Potential neonatal adverse effects include skull hypoplasia, anuria, hypotension, renal failure, and death. When pregnancy is detected, discontinue Aratan as soon as possible.

In patients with an activated renin-angiotensin system, such as volume- or salt-depleted patients (e.g., those being treated with high doses of diuretics), symptomatic hypotension may occur after initiation of treatment with Aratan. Correct volume or salt depletion prior to administration of Aratan.

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