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Arimidex (Anastrozole)

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Arimidex is an aromatase inhibitor, indicated primarily for the adjuvant treatment of postmenopausal women with hormone receptor-positive early breast cancer, the first-line treatment of postmenopausal women with hormone receptor-positive or hormone receptor-unknown locally advanced or metastatic breast cancer and the treatment of advanced breast cancer in postmenopausal women with disease progression, following tamoxifen therapy.

Other names for this medication:
Altraz, Altrol, Anabrez, Anastrocare, Anastrozole, Anatero, Anazol, Armilon, Armotraz, Femistra, Femitraz, Qubol, Redest, Rimidex, Stazonex, Xenosoul

Similar Products:
Rogaine, Thorazine, Benemid, Persantine, Valium, Floxin, Lunesta, Antabuse

Also known as: Anastrozole


Generic Arimidex is brand name for anastrozole, an oral antiestrogen. Generic Arimidex inhibits the enzyme aromatase in the adrenal glands that produces the estrogens (estradiol and estrone) and thereby lowers their levels. Generic name of Generic Arimidex is Anastrozole. Arimidex is also known as Anastrozole. Brand name of Generic Arimidex is Arimidex.


The following information describes Arimidex dosages that are commonly used or recommended. However, be sure to take the dosage your doctor prescribes for you. Your doctor will determine the best dosage to fit your needs.

Drug forms and strengths

Arimidex comes as 1-mg tablets that are taken by mouth.

Dosage for breast cancer

The usual dosage of Arimidex for breast cancer is one tablet taken once a day. It’s best to take your dose at the same time each day.

What if I miss a dose?

If you forget to take a dose of Arimidex, take the missed dose as soon as you remember. However, if it’s almost time for your next dose, just skip the missed dose and take your next dose as usual. Don’t take two doses together to make up for a missed dose.

To help make sure that you don’t miss a dose, try setting a reminder on your phone. A medication timer may be useful, too.

Will I need to use this drug long term?

Arimidex is meant to be used as a long-term treatment for breast cancer. If you and your doctor determine that Arimidex is safe and effective for you, you’ll likely take it long term.

The length of time that you’ll take this drug depends on the type of cancer you’re using it to treat. Below we describe the typical length of time that Arimidex is given. But to know for sure how long you should take Arimidex, talk with your doctor.

For advanced breast cancer

If you’re taking Arimidex to treat advanced breast cancer, you’ll usually take the drug for as long as your doctor feels this treatment is right for you. (With advanced breast cancer, the cancer has either spread to nearby areas or lymph nodes, called locally advanced breast cancer, or spread to other parts of your body, called metastatic breast cancer.)

For early breast cancer

If you’re taking Arimidex as adjuvant treatment of early breast cancer, you’ll usually take the drug for at least 5 years. Adjuvant treatment is used to lower the risk of your breast cancer coming back or spreading after it’s already been treated with surgery. (With early breast cancer, the cancer hasn’t spread out of either your breast or the lymph nodes in your armpit.)

It’s not currently known if Arimidex should be continued after these 5 years. And if so, it’s not known for how long after the first 5 years it should be taken.

Some studies found that breast cancer is less likely to come back if an aromatase inhibitor is taken for an additional 5 years after the first 5 years of adjuvant therapy. (Aromatase inhibitors are a class of medications.) With this approach to treatment, the drug would be taken for a total of 10 years. However, other studies didn’t show a benefit for extending the treatment beyond 5 the usual years.

In addition, one recent study found that taking Arimidex for a total of 10 years didn’t provide any more benefit than taking it for a total of 7 years.

How long you take Arimidex for early breast cancer will depend on how likely your breast cancer is to come back. It will also depend on your risk of side effects from treatment.


If you overdose Generic Arimidex and you don't feel good you should visit your doctor or health care provider immediately.


Store between 20 and 25 degrees C (68 and 77 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children in a container that small children cannot open.

Side effects

The most common side effects associated with Arimidex are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Arimidex can interact with several other medications.

Different interactions can cause different effects. For instance, some interactions can interfere with how well a drug works. Other interactions can increase side effects or make them more severe.

Arimidex and other medications

Below are lists of medications that can interact with Arimidex. These lists do not contain all the drugs that may interact with Arimidex.

Before taking Arimidex, talk with your doctor and pharmacist. Tell them about all prescription, over-the-counter, and other drugs you take. Also tell them about any vitamins, herbs, and supplements you use. Sharing this information can help you avoid potential interactions.

If you have questions about drug interactions that may affect you, ask your doctor or pharmacist.

Arimidex and tamoxifen

Like Arimidex, tamoxifen is a hormone therapy that’s used to treat breast cancer. But taking tamoxifen with Arimidex can lower the amount of Arimidex in your body. This can make Arimidex less effective for you.

Because of this interaction, you shouldn’t take tamoxifen with Arimidex. However, if recommended by your doctor, it’s fine to take Arimidex after you’ve finished taking tamoxifen.

Arimidex and drugs that contain estrogen

Taking Arimidex with drugs that contain estrogen could make Arimidex less effective for you. Because of this, you shouldn’t take these types of drugs while you’re using Arimidex.

Examples of drugs that contain estrogen include:

  • hormone replacement therapy (HRT)
  • vaginal estrogen products, such as creams and tablets
  • birth control medications, such as pills, patches, and vaginal rings
If you have questions about using medications that contain estrogen with Arimidex, talk with your doctor.

Arimidex and herbs and supplements

There aren’t any herbs or supplements that have been specifically reported to interact with Arimidex. However, you should still check with your doctor or pharmacist before using any of these products while taking Arimidex.

For example, it’s possible that supplements such as red clover or wild yam could make Arimidex less effective. (These supplements are used by some women to reduce menopausal symptoms, such as hot flashes.)

This interaction is possible because these supplements contain phytoestrogens, which are weak estrogen-like substances found in certain plants. There isn’t enough information available to say for sure whether taking phytoestrogens can affect your breast cancer treatment or not.

Be sure to talk with your doctor before taking any herbs or supplements with Arimidex.

Arimidex and foods

There aren’t any foods that are known to interact with Arimidex. Talk with your doctor to find out if there are any foods you should avoid during Arimidex treatment.

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