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Astrim (Trimethoprim)

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Astrim (sulfamethoxazole / trimethoprim) is absorbed by the body and begins to kill bacteria within 1 to 4 hours after taking your dose. For more common problems like urinary tract infections and ear infections, most people will start to feel relief after a few days.

Other names for this medication:
Betam, Broncoflam, Cotribene, Ditrim, Groprim, Groseptol, Ikaprim, Infectrin, Kombitrim, Licoprima, Neoset, Omsat, Ottoprim, Ribatrim, Servitrim, Sulfoid, Sulphytrim, Suprim, Theraprim, Trifen, Trimethazol, Trimosazol, Trimoxsul, Trisolvat, Zaxol

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Also known as: Trimethoprim


Astrim is effective in a variety of upper and lower respiratory tract infections, renal and urinary tract infections, gastrointestinal tract infections, skin and wound infections, septicaemias and other infections caused by sensitive organisms.

Each Astrim tablet contains 80 mg trimethoprim and 400 mg sulfamethoxazole.

Each Astrim DS (double strength) tablet contains 160 mg trimethoprim and 800 mg sulfamethoxazole.


This medication is given by injection into a vein as directed by your doctor. It is given by slow infusion over 60 to 90 minutes. Dosage is based on your medical condition, weight, and response to treatment. If you are giving this medication to yourself at home, learn all preparation and usage instructions from your health care professional. Before using, check this product visually for particles or discoloration. If either is present, do not use the liquid. Learn how to store and discard medical supplies safely. Drink plenty of fluids while taking this medication to lower the unlikely risk of kidney stones forming, unless your doctor advises you otherwise. Antibiotics work best when the amount of medicine in your body is kept at a constant level. Therefore, use this drug at evenly spaced intervals. Continue to use this medication for the full time prescribed, even if symptoms disappear after a few days. Stopping the medication too early may allow bacteria to continue to grow, which may result in a return of the infection. Tell your doctor if your condition persists or worsens.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include loss of appetite, vomiting, fever, blood in your urine, yellowing of your skin or eyes, confusion, or loss of consciousness.


Store at room temperature between 20 to 25 degrees C (68 to 77 degrees F) away from moisture, light and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Astrim are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Before using sulfamethoxazole with trimethoprim, tell your doctor or pharmacist if you are allergic to sulfa medications or trimethoprim; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney disease, liver disease, certain blood disorders (such as porphyria, anemia due to folate vitamin deficiency), history of blood disorders caused by trimethoprim or sulfa medications, vitamin deficiency (folate or folic acid), severe allergies, asthma, decreased bone marrow function (bone marrow suppression), a certain metabolic disorder (G6PD deficiency), underactive thyroid, mineral imbalances (such as high level of potassium or low level of sodium in the blood). Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). This medication may make you more sensitive to the sun. Avoid prolonged sun exposure, tanning booths or sunlamps. Use a sunscreen and wear protective clothing when outdoors. If you have diabetes, this product may affect your blood sugar levels. Check your blood sugar levels regularly as directed by your doctor. Tell your doctor immediately if you have symptoms of low blood sugar (see Side Effects section). Your doctor may need to adjust your diabetes medication, exercise program, or diet. Older adults may be more sensitive to the side effects of this drug, especially skin reactions, blood disorders, easy bleeding/bruising, and a high potassium blood level. Patients with AIDS may be more sensitive to the side effects of this drug, especially skin reactions, fever, and blood disorders. This medication is not recommended for use during pregnancy especially near the expected delivery date because of possible harm to the unborn baby. Consult your doctor for more details. This drug passes into breast milk. While there have been no reports of harm to healthy infants, this drug may have undesirable effects on infants who are ill or premature or have certain disorders (jaundice, high blood levels of bilirubin, G6PD deficiency). Therefore, breast-feeding is not recommended for infants with these conditions. Consult your doctor before breast-feeding.

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Variance, correlation and regression analysis of clinical data has allowed the identification of the predictors of therapy efficacy. Epitrochleoplasty: a method for release and protection of the ulnar nerve at the elbow. Beta-alanyl dipeptide preparations from whale muscles made by several workers. The important role of immunopathological responses in the pathogenesis of psoriasis is emphasized. Reconstitution of polymorphonuclear leukocyte cells from normal and ENL patients with ENL serum, however, showed increased Nitro Blue Tetrazolium reduction well above the normal range, whereas reconstitution with normal, lepromatous, and tuberculoid sera failed to increase Nitro Blue Tetrazolium reduction above the normal values. Copper-catalyzed hydrative amide synthesis with terminal alkyne, sulfonyl azide, and water.

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The binding of Chlamydia trachomatis and zinc to McCoy cells (mouse fibroblasts). These questions were addressed in two studies by examining time and accuracy of keystrokes in a variety of typinglike activities among typists ranging in speed from 17 to 104 net words per minute and ranging in age from 19 to 72 years old. We examined whether racial differences in patient trust are associated with physician-patient communication about lung cancer treatment. A wide variety of tumors depend on the dysregulation of Bcl-2 family proteins for survival. Studies on the interaction between manganese and fenitrothion in rats. The authors report their experience with the use of an automatic switch mechanism allowing continuous pulmonary radiograms during deep inspiration in babies and infants. This study found that adverse prognostic factors were similar to the current evidence for nonconcurrent metastatic cSCC. Proper food storage and preparation can reduce the risk of food poisoning.

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The effect of anticoagulation on antenatal ultrasound findings in pregnant women with thrombophilia. Children born during a five year period, resident in a British city, and administratively defined as mentally retarded were followed up at age 22. MspI, an isoschizomer of HpaII available from New England Biolabs, cleaves DNA irrespective of the presence of a methyl group at this position. People who were small at birth have an increased risk of type 2 diabetes in later life. We describe the clinical and histological symptoms of four women with IAPP. The evaluation of HbF as a potential plasma marker is suggested by the high concentration of FRBCs in colorectal tumours. These applications require systems that can rapidly detect small organics including nerve agents, toxic proteins, viruses, spores and whole microbes. In unstimulated peritoneal macrophages, which normally contain few tubular lysosomes and which exhibit relatively inefficient transfer of pinocytosed LY to lysosomes, such treatments had little effect on pinocytosis. Complement fixing antibodies in groups of healthy women and women with suspected infection due to Toxoplasma gondii.

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Furthermore, it seems likely that this conformation is also significant and common in other numerous unsubstituted indolealkylamines, because their conformations are similar to that of the tryptamine. Organization and chromosomal localization of the murine Testisin gene encoding a serine protease temporally expressed during spermatogenesis. Gephyrin regulates the cell surface dynamics of synaptic GABAA receptors. The effects of zimeldine and amitriptyline on car driving and psychomotor performance. Repeat resections for recurrence should be considered given the lack of other effective treatment options. This paper discusses the phenomenon of spurious or secondary association between factors in heterogeneous study populations. We report a case of Hodgkin lymphoma that developed in temporal association with the initiation of GH replacement in a 57-year-old woman with panhypopituitarism secondary to a non-secretory pituitary macroadenoma. Effects of moderator variables in reducing stress outcome in mothers of children with handicaps.

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This pilot study demonstrates that surfactant can be delivered by LMA, which leads to a significant decrease in supplemental oxygen requirement. Reliability of pelvic floor muscle strength assessment using different test positions and tools. The aim of this study was to investigate the effects of 2,4-D in mouse liver on chromosomes as well as hexokinase (HK), glucose-6-phosphate dehydrogenase (G6PD), 6-phosphogluconate dehydrogenase (6PGD), lactate dehydrogenase (LDH) and malate dehydrogenase (MDH) which are required for the generation of the pyridine nucleotide pool. To determine the correlation between transit times of retinal blood flow calculated from fluorescein angiograms and retinal blood flow determined by the microsphere method. Diagnostic possibilities of computer tomography in the thoracic area. Two spatial memories are not better than one: evidence of exclusivity in memory for object location. Malignization is associated with simplification of this regulation. Overall, all patients were improved in terms of New York Heart Association class. For several decades, the existence in some hearts of accessory conduction pathways other than the principal pathway (AV node and His bundle) has been postulated. In some forms of acquired lipodystrophy, the loss of fat is suggested to be a result of autoimmune destruction of adipocytes.

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Good overall correspondence between the the measured and calculated trends is observed. A subset of these patients is believed to benefit from putative cerebroprotective effects of anaesthetic agents is the drug soma a controlled substance . Techniques and results based on a review of the literature are first presented then analyzed. Spinal fusion surgery in older patients does not generate excess hospital-based health care use in the longer term as compared with the background population, but primary care use increases. The rationale was that psychological services should be focused where the majority of problems first present, i.e. These rats exhibited linear IgG deposits without detectable C3 deposits. At subsequent valve replacement the results of transthoracic echocardiography were confirmed in all cases. Synaptic sites on reinnervated nerve cells visualized at two different times in living mice.

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Design and analysis of association studies using pooled DNA from large twin samples. More specifically, consumption of the WB liver contributed significantly to total cadmium and lead exposure of members of the households of WB can you drink alcohol when taking bactrim hunters. The POG has already made preliminary attempts in this direction for T-ALL and B-ALL. The results suggest mobility is a strong determinant of casual sex. Biochemical assay for histone H2A.Z replacement by the yeast SWR1 chromatin remodeling complex. The problem is further complicated because the myocardial infarction may be silent. The articles showed a wide variation with respect to the surveillance intervals and recommended evaluations.

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A receiver-operating-characteristic (ROC) analysis was performed to determine a cut-off value for the BP230 ELISA. Our findings indicate that early autonomic tone balance abnormalities are present in newborns with HCA and suggest that early dynamic analysis of pulse oximetry signals could be useful in identifying affected infants. Comparative studies on the fine structure of purple membrane from Halobacterium Cutirubrum and Halobacterium Halobium. Strains of Bacteroides gingivalis were compared for the presence of properties associated with pathogenicity. In the head-up position the response to CO2 was slightly suppressed in 2 of the patients, suggesting that chemical control may have tended to compensate for CBF dysautoregulation. A high initial degree of body fat mass and high plasma NE levels as determined by the Gly16 allele for the beta2-adrenoceptor polymorphisms predict those individuals who will have rebound weight gain after their initial successful weight loss.

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Detergent solubilization of the virus particles released polyhedra containing one major structural protein. Conversely, a pBR322 DNA fragment devoid of GRE sites showed barely detectable interaction with glucocorticoid receptor in either of these assays. Physicochemical parameters pertaining to the hydrodynamics (softness degree) and electrostatics of the bacterial cell wall (HB-C12) and soft polymeric layer (HB) are quantitatively derived. Calculation of the energetics for the oligomerization of gas phase HgO and HgS and for the solvolysis of crystalline HgO and HgS. Mig1 and Mig2 coregulated the filamentous growth pathway in response to glucose limitation, as did the AMP kinase Snf1.

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Air leaks occurred,but pleural defects could not be closed by sutures and ligations. Pigmentary anomalies in ataxia--telangiectasia: a clue to diagnosis and an example of twin spotting. We optimized 11 relevant enological traits in a single clone using successive hybridization and segregation steps. A systematic review of mammography educational interventions for low-income women. CMV isolation was performed by culture on fibroblasts, shell vial technique and polymerase chain reaction (PCR) amplification of CMV DNA. They shed light on the physical interactions between a protein tyrosine kinase and a divalent metal activator. Our data confirm previous findings but also indicate differences when compared to previous reports.

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Xenopus laevis tadpoles are midwater suspension-feeders that use buccopharyngeal surfaces for both food capture and aquatic respiration, but also have functioning lungs well before metamorphosis. Numerous investigators have shown that the glycoprotein IIb/IIIa integrin mediates the final common pathway in platelet aggregation which has led to development of GP IIb/IIIa receptor antagonists. Intake of whole grains is inversely associated with risk of diabetes and ischemic heart disease in observational studies. Bacterial mutation frequency after UV irradiation and phage mutation frequency under conditions of W-reactivation were determined in A. Regulation of human peripheral blood monocyte DR antigen expression in vitro by lymphokines and recombinant interferons. A total of 330 randomly selected Saudi adolescents were included. Kindergarten students were assigned to 2 groups: those who showed mastery of skills that are important predictors of proficient reading (low-risk group) and those who initially did not show mastery but later benefited from systematic reading instruction and developed average-range reading skills at the end of Grade 1 (high-risk responders). Studies on the kinetics of lactate dehydrogenase (EC, malate dehydrogenase (E.C. M gallisepticum could be recovered readily from respiratory tissue 10 and 30 days after infections but RSA tests were negative.

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Their geometrical configurations are key to a well-defined control and operation of the AND port. In relation to pentachloronitrobenzene, no increasing fungistatic activities were found with cysteine derivatives. Disruption of the Arabidopsis SMC4 gene, AtCAP-C, compromises gametogenesis and embryogenesis. The genomic DNAs were selected from assemblages A (WB) and B (GS) as reference and plasmids were constructed. Thirty-nine patients with chronic constipation based on Rome III criteria and 147 patients with normal bowel habits were included. The pattern of symptoms in patients receiving home based care in Bangwe, Malawi : a descriptive study. Reducing the risk of interval colorectal neoplasia: high magnification chromoscopic colonoscopy may offer a key resource?. More intensive prescriptions would enhance biodiversity because positive responses of early successional species exceeded negative responses of late successional species within the heavily forested study area.

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In this paper, we review the response of plasma para que sirve el enalapril 20 mg insulin-like growth factor-I (IGF-I) to quantity and nutritional quality of dietary proteins. The deduced amino acid sequence consisted of 318 amino acids and shared sequences conserved in many serine proteases. The presence of an inflated compression balloon in the stomach may narrow the artery, presumably by placing tension on the median arcuate ligament of the diaphragm. Effect of volume history on distribution of inspired gas in asthmatics. Recombinant barley high pI alpha-glucosidase was produced by high cell-density fermentation of Pichia pastoris expressing the cloned full-length gene. High metabolic process, induced due to high nutritional intake, results to endoplasmic reticulum (ER) stress and mitochondrial stress. The misdiagnosis of epilepsy in children admitted to a tertiary epilepsy centre with paroxysmal events. Effects of Staphylococcus aureus on the ciliary activity of the middle ear lining.

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