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Avdol (Tramadol)

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Avdol is a strong painkiller used to treat moderate to severe pain. It is generally used when non-opioid painkillers don't work as well to control the pain anymore. Avdol may cause drowsiness. You shouldn't drive or use heavy machinery or perform dangerous activities until you know how this drug affects you.

Other names for this medication:
Adamon, Bramadol, Cadol, Cosdol, Hyperdol, Lagesic, Leedol, Mobiya, Neutram, Nopidol, Pentazen, Servodol, Spasteez, Supridol, Tacil, Tamody, Taramol, Traceta, Tramadol, Tramex, Trapidol, Trectadol, Trofel, Tromar, Urgendol, Urogendo, Xtram

Similar Products:
Claritin, Mobic, Atarax, Ovral, Nolvadex, Compazine, Pepcid, Phenergan

Also known as: Tramadol


{name} ER is an pain medicine similar to an opioid. This medicine is used to treat moderate to severe pain.

The extended-release form of tramadol is for around-the-clock treatment of pain. This form of tramadol is not for use on an as-needed basis for pain.


Follow the directions on your prescription label and read all medication guides. Never use Avdol ER in larger amounts, or for longer than prescribed. Tell your doctor if you feel an increased urge to take more of Avdol ER.

Never share Avdol ER with another person, especially someone with a history of drug addiction. MISUSE CAN CAUSE ADDICTION, OVERDOSE, OR DEATH. Keep the medicine where others cannot get to it. Selling or giving away this medicine is against the law.

Stop taking all other opioid medications when you start taking Avdol ER.

Avdol ER can be taken with or without food, but take it the same way each time.

Swallow the capsule or tablet whole to avoid exposure to a potentially fatal overdose. Do not crush, chew, break, open, or dissolve.

Measure liquid medicine with the supplied syringe or a dose-measuring device (not a kitchen spoon).

Never crush or break a Avdol ER pill to inhale the powder or mix it into a liquid to inject the drug into your vein. This practice has resulted in death.

You may have withdrawal symptoms if you stop using Avdol ER suddenly. Ask your doctor before stopping the medicine.

Store at room temperature away from moisture and heat. Keep track of your medicine. You should be aware if anyone is using it improperly or without a prescription.

Do not keep leftover Avdol ER. Just one dose can cause death in someone using it accidentally or improperly. Ask your pharmacist where to locate a drug take-back disposal program. If there is no take-back program, mix the leftover medicine with cat litter or coffee grounds in a sealed plastic bag throw the bag in the trash.

Detailed Avdol ER dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose can be fatal, especially in a child or other person using the medicine without a prescription. Overdose symptoms may include severe drowsiness, pinpoint pupils, slow breathing, or no breathing.

Your doctor may recommend you get naloxone (a medicine to reverse an opioid overdose) and keep it with you at all times. A person caring for you can give the naloxone if you stop breathing or don't wake up. Your caregiver must still get emergency medical help and may need to perform CPR (cardiopulmonary resuscitation) on you while waiting for help to arrive.

Anyone can buy naloxone from a pharmacy or local health department. Make sure any person caring for you knows where you keep naloxone and how to use it.


Store at room temperature below 30 degrees C away from excess moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Avdol are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not take Avdol if you are allergic to tramadol, or if you have:

severe asthma or breathing problems; a stomach or bowel obstruction (including paralytic ileus); if you have recently used alcohol, sedatives, tranquilizers, or narcotic medications; or if you have used an MAO inhibitor in the past 14 days (such as isocarboxazid, linezolid, methylene blue injection, phenelzine, or tranylcypromine).

Avdol should not be given to a child younger than 12 years old. Avdol ER should not be given to anyone younger than 18 years old.

Do not give Avdol to anyone younger than 18 years old who recently had surgery to remove the tonsils or adenoids.

Seizures have occurred in some people taking Avdol. Your seizure risk may be higher if you have ever had:

a head injury, epilepsy or other seizure disorder; drug or alcohol addiction; or a metabolic disorder.

To make sure Avdol is safe for you, tell your doctor if you have ever had:

breathing problems, sleep apnea; liver or kidney disease; urination problems; problems with your gallbladder, pancreas, or thyroid; a stomach disorder; or mental illness, or suicide attempt.

If you use tramadol during pregnancy, your baby could be born with life-threatening withdrawal symptoms, and may need medical treatment for several weeks.

Ask a doctor before using tramadol if you are breastfeeding. Tell your doctor if you notice severe drowsiness or slow breathing in the nursing baby.

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Secukinumab efficacy and safety in Japanese patients with moderate-to-severe plaque psoriasis: subanalysis from ERASURE, a randomized, placebo-controlled, phase 3 study. Prolonged stimulation of the adrenals by corticotropin suppresses hepatic low-density lipoprotein and high-density lipoprotein receptors and increases plasma cholesterol. We study electrostatic interactions of polystyrene particles at an oil/water interface controlled by a chemical reaction of carboxylate surface functional groups. In recent years, the incidence rate of childhood tuberculosis (TB) in Japan has declined steadily and it reached at a lower level than that in U.S. Catalase is a scavenger of hydrogen peroxide and presumably protects against the cytolytic effects of reactive oxygen metabolites.

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These concurrent and prospective associations were independent of expected symptom trajectories informed by individual risk factors. In the majority of the lateral septal neurons, iontophoretically applied AVP induced a marked increase in the excitatory responses to glutamate, aspartate, quisqualate and N-methyl-D-aspartate. Evidence for cooperativity in the rejection of cardiac grafts mediated by CD4 TCR Tg T cells specific for a defined allopeptide. These results are similar to those found with drug binding to the SMR protein EmrE in an earlier study. Women with breast implants constitute a growing proportion of the female population in Denmark. The result revealed that the institutions were not producing the graduates upon their capacity, only 1,451 staff nurse graduated annually against the capacity of producing 4,017 per annum. It is concluded that the increased muscle tone observed with ATX II may reflect a summation of increased fibrillatory activity. Release of Rho-specific nucleotide exchange factor GEF-H1 from microtubules activates the Rho pathway of EC permeability. We attempted to correlate surgical treatment and outcomes over time.

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Canadian Association of Gastroenterology position statement: fecal microbiota transplant therapy. Both pre- and postoperative UVG evaluated the posterior-urethral vesical angle and position of the urethrovesical junction. The findings provide cross-cultural support for the multidimensional model of schizotypy and schizophrenia. Clinical isolates were molecularly characterized using IS6110-based RFLP analysis and spoligotyping methods to identify patients infected with the same strain. Laminate veneers are widely used in the management of unesthetic anterior teeth. The method was applicable both to DNA extracted from pure cultures and to DNA extracted from fresh or frozen H. The function of DAX1 as an antagonist of SF1 in gonadal development is consistent with the fact that in humans, duplication of the region of the X chromosome containing DAX1 causes a similar phenotype as mutations in SF1.

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The PIIP and UCIP are crucial to understanding the relationship of the insula with the posterior limb of the internal capsule including the corticospinal tract. The frequency of abnormal bile acids was greater than that of the standard liver function tests except for alkaline phosphatase in liver cancer. An evaluation of the image quality of scanning equalization radiography (SER) of the chest was conducted with 60 volunteer patients. Tight linkage between the syndrome of generalized thyroid hormone resistance and the human c-erbA beta gene. The purpose of this study was to (1) determine the accuracy with which the BGS tracks the hip joint through repositioning and (2) identify improvements to the workflow. To explore the mechanism of nourishing kidney and reducing urine effect of suoquan capsule by discussing the adjusting action on ALD synthase.

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Overcoming barriers to HPV vaccination: non-inferiority of antibody response to human papillomavirus 16/18 vaccine in adolescents vaccinated with a two-dose vs. Isolation and characterization of autophagic vacuoles from rat kidney cortex. Among the occupational group, irritants were of much greater importance than allergens. Administration of 3,5-T2 to hypothyroid rodents rapidly stimulated their basal metabolic rate, prevented high-fat diet-induced obesity as well as steatosis, and increased oxidation of long-chain fatty acids. Obesity hypertension may be the result of an inappropriately raised cardiac output in the presence of a relatively restricted arterial capacity due to the low vascularity of adipose tissue. Taurine applied to mouse brain slices evokes a long-lasting enhancement (LLE) of corticostriatal synaptic transmission, LLE(TAU). Long-lived individuals are rare and may be selected in part for the genetic factors that promote successful aging. Band gap opening in silicene on MgBr2(0001) induced by Li and Na.


Given the PCR protocol, the midpoint cycle number (where the template concentration is half that of the final concentration) can be theoretically determined and graphed for a variety of initial DNA concentrations. Structured interviews with leading private payers representing over 110 million commercially-insured lives exploring current and planned use of P4P provider payment models, evidence requirements for technology assessment and new technology coverage, and the evolving relationship between the two topics. The on-center cells were activated during increasing luminance, the off-center cells during decreasing luminance. A scanning electron microscopic (SEM) investigation of endothelial behavior, following carotid end-to-side microsurgical anastomoses, was carried out in twenty-four Sprague-Dawley rats. Determinants of altered sleep-wake rhythmicity in patients treated for nonfunctioning pituitary macroadenomas. Two cases of dyschromatosis universalis hereditaria (DUH) from a Chinese family are presented.

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Expression of hypoxia-inducible factor 1 alpha and oligodendrocyte lineage gene-1 in cultured brain slices after oxygen-glucose deprivation. Based upon this framework we encoded and implemented several CPGs in varying medical domains. Trypanosoma brucei has ocyltransferose and phospholipase A(1) activities for the metabolism of exogenous lysophospholipids. The active phase of labor was prolonged by an average of 60 minutes and the 2nd stage by an average of 36 minutes regardless of the type of epidural compared with controls. To examine the relationship between the severity of cartilage damage and the severity of meniscus damage after transection of the anterior cruciate ligament (ACLT) in adult dogs. This study measured the longitudinal relaxation rate constants (R1 ) over a concentration range for non-protein-binding and protein-binding CRs in ex vivo whole blood and plasma at 1.5 and 3.0 Tesla (T) under physiologic arterial conditions. The Complex Emergency Database: a global repository of small-scale surveys on nutrition, health and mortality.

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BAX and BAK are critical mediators of B cell death induced by multiple stimuli. Ectodermal Defects and Anal Atresia in a Child with a TP63 Mutation--Expanding the Phenotypic Spectrum. EESI-MS shows excellent performance for monitoring uranium species in various samples at trace levels since it tolerates extremely complex matrices. The size of the lesion and cortical erosion seen on the computed tomography scan help in differentiating the osteoid osteoma and osteoblastoma, but they are less sensitive and specific. Self-reported management of pain in hospitalized patients: link between process and outcome. The role of the locus coeruleus in corticotropin-releasing hormone and stress-induced suppression of pulsatile luteinizing hormone secretion in the female rat. The adhesins are usually composed of proteins in the form of fimbriae or fibrillae and the receptors of glycolipids or glycoproteins. This article reviews recent advances in central airway imaging with MDCT.

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Innovative approaches were developed for assessing the ankle-brachial index using an automatic device instead of the mercury column to measure blood pressure and for assessing the anterior-posterior diameter of the right lobe of the liver by ultrasound for quantitative assessment of nonalcoholic fatty liver disease. The use of hyaluronidase reduced the patient discomfort within 24 to 48 hours, deterring any patient anxiety or patient dissatisfaction. The reason why the observed characteristics of these NTFET biosensors differed among the devices was that the carbon nanotube (CNT) that formed the channel was not uniform. This phenomenon was different from risperdal dose titration the typical smile responses we have observed in obsessive-compulsive disorder cases. The findings highlight the importance of offering appropriate instruction on smoking cessation to students in nursing schools in Japan.

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The musculoskeletal system is largely regulated through dynamic physical activity and is compromised by cessation of physical loading. Persistence of inflammatory M1 macrophages may derail healing and compromise organ functions. Paracoccidioidomycosis is a systemic fungal infection common in Latin America. Non-tuberculous mycobacterial lung disease (NT MLD ) in patients with chronic thromboembolic pulmonary hypertension and idiopathic pulmonary arterial hypertension. Analyses of the data for these 13 categories of leaves identify seven statistically significantly different modes of A vs.

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An evaluation study on rural roads in the Dutch province Friesland. The primary analysis compared time-to-death between patients receiving no shocks and patients receiving shocks of any type adjusted for SHFM score at time of implantation and other comorbidities. Several plants are traditionally used to treat mental diseases in South Africa. Studies on IAP catalyzed 32P-ADP-ribosylation of astroglial cell particulate material revealed an incorporation of radiolabel into three polypeptides in the molecular weight range of 41,000-39,000 Dalton. Volumes of neuronal loss were calculated and compared between groups by analysis of variance.

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Green tea and vitamin C ameliorate some neuro-functional and biochemical signs of arsenic toxicity in rats. We consider an inhomogeneous substrate for Marangoni convection. Our results showed that the embryonic stem cell-derived macrophages (ES Mphi) had a more similar expression profile to peritoneal xanax drug classification dsm macrophages than the two mouse macrophage cell lines. Conversely, autophagy regulates ciliogenesis by controlling the levels of ciliary proteins. Nevertheless, a need for simple, rapid, and cost-effective molecular protocols to accurately discriminate between D. Arrows of time in infancy: the representation of temporal-causal invariances. Here, we explore these phenomena for endocrine-active steroid hormones, focusing on examples of conserved bioactivity and related implications for fate assessment, regulatory approaches, and research opportunities. Efficacy and safety of iodopovidone pleurodesis through chest tube in spontaneous pneumothorax. Residents with AUD diagnoses functioned somewhat better than demographically matched controls. Models predict a significant reduction in reef spatial extension together with a decline in biodiversity in the relatively near future.

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This means simply offering coverage to individuals with MD may not be sufficient in eliminating health disparities. Overall, a low pH of weakly acidic reflux represents a determinant factor in provoking heartburn. When growing up, the pharmacokinetic (PK) and pharmacodynamic (PD) profiles of drugs change, which may alter the effect of drugs. These results suggest that H2 antagonist prevented the whealing reaction by changing the vascular reaction to secreted or exogenous histamine. The highest insecticidal activity was obtained for beta-photogedunin. Fluorinated vitamin D analogs to probe the conformation of vitamin D in its receptor complex: 19F-NMR studies and biological activity. Beyond the second hour FA Ca remained slightly depressed with somatostatin, but was not significantly different from the basal conditions. A midline sagittal scan of the fetal pelvis, perineum and external genitalia was obtained and observed continuously during fetal micturition. Together, these results indicate that the level of stimulation experienced by C. Our data suggest that modulation of integrin binding by FIII9 may arise in part from its steric properties that determine accessibility of the RGD motif.

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It is timely to review the existing data on this procedure derived from European, Australian, and American studies and compare and contrast their results. Serum and whole blood concentrations of fat and water soluble vitamins in normal persons and athletes. Numerous treatments are available for type 2 diabetes mellitus (T2DM), which can improve insulin sensitivity or stimulate its secretion. Theophylline did not have any direct effect on e.j.p.s nor did it reverse the effects of adenosine or 2-chloroadenosine. As such, we suggest the continued use of SSEP alone in idiopathic scoliosis surgeries.

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Fructus Ligustri Lucidi (FLL) ethanol extract increases bone mineral density and improves bone properties in growing female rats. Thrombosis of the veins and thromboembolism of the pulmonary artery in patients with cerebral insult (clinico-morphological study). An 81-year-old man presented with poor visual acuity of the left eye, swelling of the left eyelid, and elevation of the left intraocular pressure after contusion of the left palpebral portion. Underlying any understanding of the mode, tempo and relative importance of the adaptive process in the evolution of natural populations is the notion of whether adaptation is mutation limited. The model is trained by a procedure combining an EM algorithm and model selection techniques. Nuclear export of mRNA is a central step in gene expression that shows extensive coupling to transcription and transcript processing.

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Multiphoton imaging has evolved as an indispensable tool in cell biology and holds prospects for clinical applications. Mean fluorescence intensity (MFI) was evaluated for HLA-DR expression for each DC subtype. Establishing a mental health consultation program with a police department. Uterine artery embolization has become an adjuvant treatment, although the potential for obstetric hemorrhage still exists. The location of the eyebrow relative to the center of the pupil, the lateral canthus, and the depth of the supraorbital rim was measured. Mental health reform in Ontario is moving in the direction of community-based delivery of mental health services. The balance of these two factors produces the observed bi-directional shift of the modes while they both contribute to promoted quality factor after coating. Left ventricular morphology and function in patients with atherosclerotic renovascular disease. There are not many studies about treatment of glyburide dose route shoulder spasticity.

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