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Benforce (Metformin)

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Benforce is an anti-diabetic medication (biguanide). It works by lowering glucose production in the liver, delaying the absorption of sugar (glucose) from the intestines, and increasing the body's sensitivity to insulin.

Other names for this medication:
Asoride, Cetapin, Chromet, Daomet, Diamin, Dmbest, Duomet, Enselin, Formet, Glatix, Glidiet, Glinate, Glucoact, Glycimex, Glycirest, Glycurb, Glycurub, Glyrep, Jalra, Matce, Mefinda, Metaday, Mintide, Nilconorm, Rozyformin, Secrin, Tgmet, Voglinorm, Zeformin, Zomelis

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Plavix, Eulexin, Imovane, Cardura, Keflex, Vermox

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Also known as: Metformin


{name} XR is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus.

{name} XR is sometimes used together with insulin or other medications, but this medicine is not for treating type 1 diabetes.


Benforce can be taken in form of pills and extended-release pills which should be taken by mouth. It is better to take Benforce every day at the same time with meal or without it. Usual Benforce dosage is taken 2-3 times a day with meals. Benforce XR (extended-release tablets) is taken once a day with evening meal. Take Benforce and remember that its dosage depends on patient's health state. Benforce can't be used by patients under 10 years. Benforce XR (extended-release tablets) can't be used by patients under 17 years. It can be dangerous to stop Benforce taking suddenly.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose can cause severe hypoglycemia or lactic acidosis.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Benforce are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not use MetFORMIN (Eqv-Benforce XR) if you are allergic to it, or if you have:

severe kidney disease; or metabolic acidosis or diabetic ketoacidosis (call your doctor for treatment).

If you need to have surgery or any type of x-ray or CT scan using a dye that is injected into your veins, you may need to temporarily stop taking MetFORMIN (Eqv-Benforce XR). Be sure your caregivers know ahead of time that you are using this medication.

Tell your doctor if you have ever had:

kidney disease (your kidney function may need to be checked before you take this medicine); high ketone levels in your blood or urine; heart disease, congestive heart failure; liver disease; or if you also use insulin, or other oral diabetes medications.

You may develop lactic acidosis, a dangerous build-up of lactic acid in your blood. This may be more likely if you have other medical conditions, a severe infection, chronic alcoholism, or if you are 65 or older. Ask your doctor about your risk.

Follow your doctor's instructions about using this medicine if you are pregnant or you become pregnant. Controlling diabetes is very important during pregnancy, and having high blood sugar may cause complications in both the mother and the baby.

MetFORMIN (Eqv-Benforce XR) may stimulate ovulation in a premenopausal woman and may increase the risk of unintended pregnancy. Talk to your doctor about your risk.

You should not breastfeed while using this medicine.

MetFORMIN (Eqv-Benforce XR) should not be given to a child younger than 10 years old. Some forms of MetFORMIN (Eqv-Benforce XR) are not approved for use by anyone younger than 18 years old.

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Cross-sectional study of 91 women with oligomenorrhea or amenorrhea and elevated serum testosterone, followed by an OGTT in 27 of the women. Additionally, real-time dust exposure was measured using a DataRAM monitor in 12 grass seed workers to obtain more information on exposure patterns during specific tasks. Molecular typing by pulsed field gel electrophoresis (PFGE) with the restriction enzymes SmaI, SalI and KpnI, yielded unique profiles for most unrelated strains but indistinguishable profiles for all isolates from the same outbreak. A mouse model with a genetic deletion of Pak1 (Pak1(-/-)) was used to determine the role of Pak in the response of the airways in vivo to challenge with inhaled or intravenous acetylcholine (ACh). The Dretler Stone Cone effectively prevents proximal stone migration and facilitates stone fragmentation during pneumatic lithotripsy with no risk of ureteral injury. Maps of both sets of peptides demonstrate a marked similarity between the two parent polypeptides. We report on clinical and laboratory findings of 28 patients with tick-bite Borrelia burgdorferi-infection. Our data indicate that punishment-induced suppression of alcohol-taking behavior is context-dependent. In mice, embryonic stem cell cultures are routinely used for gene transfer and provide the advantage of in vitro selection for rare events such as homologous recombination and targeted mutation. Data were generated from 221 patients with C1 inhibitor deficiency by asking them about symptoms they experienced during their edema episodes.

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Depletion of adherent monocytes from mononuclear cells from a patient with acute GVHD and deficient Con A-induced suppressor function, restored the suppressor function, demonstrating the role of monocytes for deficient Con A suppressor function in some patients with acute GVHD. The local coding, which is carried out on the locally linear manifold, can extract the salient feature of image patches and leads to a sparse measure matrix on which maximum pooling is carried out. The influence of population structure on the probability of occurrence of complete gene substitution is discussed on the basis of a numerical example. Beyond the specific applicability to storage devices, the possibility of a two-phase effect on mass storage generally highlights the availability of novel degrees of freedom in materials research when dealing with nanocomposites. Steam versus hot-water scalding in reducing bacterial loads on the skin of commercially processed poultry. Proteomic analysis reveals the spatial heterogeneity of immobilized Taxus cuspidata cells in support matrices. Application of the method to the diffusion of the superoxide anion to the protein superoxide dismutase revealed that the electric field of the enzyme enhances the association rate of the anion by a factor of 30 or more. Psychological hazards involved in treatment of medical colleagues. Neomycin displayed higher blockade with a half inhibition in the nanomolar range at low calcium concentration and in the micromolar range in physiological calcium concentration but still exerted blockade below the concentration used in the clinic. In particular, the mass spectral investigation indicated the cleavage of the 2,3- and 4,5-ring bonds, in contrast with the usual behavior of other thiazole derivatives with no triphenylmethyl substituent.

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The majority of RAEs identified, transcribed, and entered are not clinically important. Digestion of amniotic fluid with bromelain produces a rapidly-migrating active enzyme form, with a molecular weight of about 135,000, compared with 145,000 for the fetal intestinal phosphatase in serum. Evidence supporting an association between osteoporosis and loss of alveolar crestal bone is limited. Rats made congenic for Oia3 on chromosome 10 become susceptible to squalene-induced arthritis. A synopsis of the methods implemented in such studies (populations studied, measurements strategies, questionnaires on time-activity patterns, residences and work place) was detailed. Balloon catheter dilation of a stenotic renal artery can cure or enable easy medical control of renovascular hypertension when vessel narrowing is caused by fibromuscular dysplasia or an isolated atherosclerotic plaque in the main renal artery. These proteins were not detectable in nonpermissive cells in course of these experiments, although the corresponding mRNAs were synthesized. Likewise were both mixed lymphocyte reaction (MLR) and autologous mixed lymphocyte reaction (AMLR) severely hampered while stimulation induced by mitogens was only minimally affected.

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The minimum Na concentration permitting growth consistently was 15 mM. All patients with secondary involvement and/or urologic complications had undergone previous pelvic surgery. Inappropriate dietary habits, overweight and lifestyle are suggested to contribute considerably to the increasing incidence and prevalence of urolithiasis. The guidelines of the Society of Infectious Pathology of French Language (SPILF) for the prevention of infective endocarditis of at-risk patients were updated in 2002. Experimental study of the effect of nonachlazine on the functional activity of the thrombocytes. We tested Ho:YAG and Er:YAG laser ablation of human urinary calculi to determine if Er:YAG is a more efficient lithotripsy device.

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Transvenous double-balloon occlusion of the persistent ductus arteriosus: an experimental study. Its immunosuppressive activity results from binding to receptor proteins designated as immunophilins (i.e., FKBP12, FK506 binding protein). The role of dentistry in the medical evaluation of general health. coli to aggressively macerate tuber tissue and that deletion of pelE significantly diminishes the virulence of E. Since most of the grain yield of rice comes from the photosynthesis of flag leaves, the similar Asat and much higher AQY, CE and PhiCO2 at heading stage of the two super-rice hybrids indicates that higher photosynthetic efficiency rather than higher photosynthetic capacity may be the primary factor contributing to their higher grain yields. Therefore, a continuous physical map covering the entire ovine autosome inversion/insertion region was successfully constructed. Aprotinin in major orthopedic surgery: a systematic review of randomized controlled trials.

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Responses at frequencies bands centered on 0.8, 1.6, 2.4, 3.2 and 4.0 kHz, as well as total emission responses, were analyzed. Milk odd and branched-chain fatty acids to predict ruminal methanogenesis in dairy cows. This brief review will focus on the interactions of three known neurotoxicants, lead, ethanol and polychlorinated biphenyls, with signal transduction pathways, particularly the family of protein kinase C isozymes, and discusses how such effects may be involved in their neurotoxicity. Thus, a conjoint project of the statutory pension and health insurance institutes to assess and to describe the structure quality of in-patient medical rehabilitation clinics for children and adolescents was initiated. In contrast, the meat consumption of women and younger people was strongly associated with more specific concerns about lack of iron and protein in the vegetarian diet. Rejection of lamb carcasses due to a strong potato odor was caused by Pseudomonas taetrolens. We screened the MAGEL2 open reading frame for mutations in genomic DNA samples from hyperphagic but non-dysmorphic individuals with severe childhood-onset obesity. DBC1 re-expression alters the expression of multiple components of the plasminogen pathway.

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A new beta-lactamase (carbenicillinase) in Pseudomonas aeruginosa. Collateral vessels in the pelvic or paravertebral plexus and dilated veins in the abdominal skin are indirect evidence of ileo-caval thrombosis. Percutaneous absorption is influenced by a large number of factors. Childbirth and the development of acute trauma symptoms: incidence and contributing factors. A novel computer-assisted algorithmic method for differential diagnosis of dermatological diseases. A Pseudomonas stutzeri gene cluster encoding the biosynthesis of the CCl4-dechlorination agent pyridine-2,6-bis(thiocarboxylic acid). One patient had a mixed clinical response with reduction of bone pain.

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