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Bicofen (Roxithromycin)

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Bicofen is a semi-synthetic macrolide antibiotic. It is a white crystalline powder. Bicofen is very slightly soluble in water, freely soluble in acetone, in alcohol and in methylene chloride. It is slightly soluble in dilute hydrochloric acid.

Other names for this medication:
Acevor, Aristomycin, Asmetic, Bazuctril, Biaxsig, Bicofen, Biostatik, Cadithro, Claramid, Crolix, Delos, Erybros, Floxid, Infectoroxit, Macrolid, Monobac, Nirox, Odonticina, Overal, Pedilid, Ramivan, Redotrin, Remora, Renicin, Rokilide, Rokithrid, Roksimin, Roksolit, Rolexit, Rolicyn, Rolid, Romyk, Rossitrol, Rotramin, Roxithromycine, Roxithromycinum, Roxitromicina, Rulid

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Also known as: Roxithromycin


Each Bicofen tablet contains either 150mg or 300mg of the active ingredient roxithromycin. Each tablet also contains: hydroxypropylcellulose, poloxamer, povidone, colloidal anhydrous silica, magnesium stearate (470), purified talc (553), maize starch, hypromellose, anhydrous glucose, titanium dioxide (171), propylene glycol (1520). Bicofen does not contain gluten, sucrose, lactose, tartrazine or any other azo dyes.


Bicofen is typically prescribed for a period of 7 to 14 days and patients should take the medication for as long as it has been prescribed to prevent the infection from returning even if they become asymptomatic. Patients should not however, take doses larger than has been prescribed as this can result in an overdose. Overdosing requires immediate medical intervention and may present with symptoms which include abdominal pain, nausea, diarrhea, vomiting, and a general and prolonged feeling of illness.


Immediately telephone your doctor or pharmacist. Do this even if there are no signs of discomfort or poisoning.


Keep your tablets in the blister pack until it is time to take them. If you take the tablets out of the blister pack they may not keep well.

Keep the medicine in a cool, dry place where the temperature stays below 25 degrees C.

Do not store it or any other medicine in the bathroom, near a sink or on windowsill.

Do not leave it in the car. Heat and damp can destroy some medicines.

Keep it where children cannot reach it. A locked cupboard at least one-and-a-half metres above the ground is a good place to store medicines.

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The most common side effects associated with Bicofen are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not take Generic Bicofen if you are allergic to Generic Bicofen components. Try to be careful with Generic Bicofen if you're pregnant or you plan to have a baby, or you are a nursing mother. It can be dangerous to stop Generic Bicofen taking suddenly.

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Effects of intra- and extracellular injected prostaglandins (PG) E2 and F2 alpha on chemosensitivity to transmitter substances as well as on electrical activity of identified neurons were studied in the snail Helix pomatia. These results are consistent with the possibility that oestradiol alters transcription in the neonatal rat brain and may do this through the oestrogen receptor.(ABSTRACT TRUNCATED AT 250 WORDS). This study was designed to investigate the effects of alpha-tocopherol alone and a mixed tocopherol preparation (gamma-, delta-, and alpha-tocopherol) on hydrogen peroxide-induced lipid peroxidation in human erythrocytes. We sought to investigate the clinicopathologic features, surgical outcomes, and prognostic factors of curatively resected pathologic T4b gastric cancer with a focus on organs invaded. Covalent docking of large libraries for the discovery of chemical probes. The distribution of actin and Rho was affected by toxin B and, in dark-adapted retinas, actin and Rho distribution was similar to that observed in the light. The effect of glucocorticoid hormones on release of HBsAg from PLC/PRF/5 (Alexander) hepatoma cells.

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