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Biocal (Calcitriol)

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Biocal is an active metabolite of vitamin D that is used to treat hyperparathyroidism and is also used in dialysis patients to combat hypocalcemia. Biocal is a biologically active calcitrophic hormone with anti-osteoporotic, immunomodulatory, anticarcinogenic, antipsoriatic, antioxidant, and mood-modulatory activities.

Other names for this medication:
Alcee, Alfacalcirol, Alfacip, Alfarich, Arcium, Aristrol, Biocal, Calbovic, Calcimet, Calcirol, Calcit, Calcor, Calday, Caldikind, Calgel, Calosto, Calotec, Calsonic, Calsure, Caltop, Calzem, Cholical, Citroj, Coecoral, Denscal, Dmcal, Laretol, Minroset, Novadee, Osteobel, Ostonex, Politrol, Refirm, Rical, Riecal, Rockbon, Rolsical, Septriol, Solbiocal, Statbone, Sunmic, Tobalt, Vezocal, Zaxial

Similar Products:
Geodon, Elocon, Ceftin, Urispas, Coumadin, Valtrex, Calan

Also known as: Calcitriol


Generic Biocal is a synthetic vitamin D analog which is active in the regulation of the absorption of calcium from the gastrointestinal tract and its utilization in the body. The two known sites of action of Generic Biocal are intestine and bone. Generic Biocal receptor-binding protein appears to exist in the mucosa of human intestine. Additional evidence suggests that Generic Biocal may also act on the kidney and the parathyroid glands. Generic Biocal is the most active known form of vitamin D3 in stimulating intestinal calcium transport. In acutely uremic rats Generic Biocal has been shown to stimulate intestinal calcium absorption. The kidneys of uremic patients cannot adequately synthesize Generic Biocal, the active hormone formed from precursor vitamin D. Resultant hypocalcemia and secondary hyperparathyroidism are a major cause of the metabolic bone disease of renal failure. However, other bone-toxic substances which accumulate in uremia (eg, aluminum) may also contribute. The beneficial effect of Generic Biocal in renal osteodystrophy appears to result from correction of hypocalcemia and secondary hyperparathyroidism. It is uncertain whether Generic Biocal produces other independent beneficial effects. Biocal is also known as Calcitriol. Generic Biocal treatment is not associated with an accelerated rate of renal function deterioration. No radiographic evidence of extraskeletal calcification has been found in predialysis patients following treatment. The duration of pharmacologic activity of a single dose of calcitriol is about 3 to 5 days. Generic name of Generic Biocal is Calcitriol. Brand name of Generic Biocal is Biocal.


Generic Biocal is available in capsules (0.25 mcg) and liquid form. Capsules must be swallowed whole. Do not crush or chew them. If you are prescribed the liquid form, use as directed. Follow dosing instructions closely. Do not take this medication with mineral oil or magnesium containing antacids which may reduce its effects. Foods rich in vitamin D include: fortified dairy products, eggs, sardines, cod liver oil, chicken livers and fresh-water fish. Vitamin D is also obtained from periodic exposure to the sun. It is important to maintain a well-balanced diet while taking this medication. Calcium supplements may be recommended in addition to this medication. If you want to achieve most effective results do not stop taking Generic Biocal suddenly.


If you overdose Generic Biocal and you don't feel good you should visit your doctor or health care provider immediately.


Keep out of the reach of children.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Do not keep outdated medicine or medicine no longer needed.

Side effects

The most common side effects associated with Biocal are:

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Inferring developmental stage composition from gene expression in human malaria. Somatosensory evoked responses in carbon monoxide poisoned subjects. Self-pulsating sources based on cascaded regeneration by self-phase modulation and offset filtering are investigated experimentally using large filter bandwidths of 3.5 nm and up to semi-infinite bandwidths. The lung W/D and the protein content in BALF in hyperoxia group were significantly higher than those in atmospheric air groups. In the dome pretreated with propranolol (10(-6) M), phenylephrine (10(-5) M-10(-3) M) and norepinephrine (10(-7) M-10(-5) M) caused only a small contraction but norepinephrine, only at high concentrations (10(-4) M-10(-3) M), produced a small relaxation. The pattern of gastrointestinal lymphoma in Iran is very similar to the Western countries. For the patient studies, we compared organ activity estimates at 24 h after injection with those from conventional geometric mean-based planar quantification using a 24 h post-injection quantitative SPECT reconstruction as the gold standard.

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We evaluated the rate of serious adverse events during sedation (SAEDS) in patients who had an IOP (case subjects) and in patients who had a closed reduction of a forearm fracture (controls) and compared the 2 cohorts. Immunopathogenesis of oropharyngeal candidiasis in human immunodeficiency virus infection. No single pulmonary-specific variable, including the severity of hypoxemia, has been found to predict the risk of death independently when measured early in the course of the acute respiratory distress syndrome. 1,5-Disubstituted indole derivatives as selective human neuronal nitric oxide synthase inhibitors. Posttranscriptional regulation of the RAD5 DNA repair gene by the Dun1 kinase and the Pan2-Pan3 poly(A)-nuclease complex contributes to survival of replication blocks.

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