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Biolar (Lorazepam)
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Biolar

Biolar, an antianxiety agent, has the chemical formula, 7-chloro-5-(o-chlorophenyl)-1,3- dihydro-3-hydroxy-2H-1,4-benzodiazepin-2-one. It is a nearly white powder almost insoluble in water. Each Biolar tablet, to be taken orally, contains 0.5 mg, 1 mg, or 2 mg of lorazepam. The inactive ingredients present are lactose monohydrate, magnesium stearate, microcrystalline cellulose, and polacrilin potassium.

Other names for this medication:
Almazine, Anxilor, Anxionil, Anxipose, Atipam, Biokalm, Biolar, Calmese, Dulozep, Larosh, Larpose, Lopam, Lopez, Loracalm, Lorakar, Loralite, Lorazam, Lorazepam, Lorazine, Loricon, Loripam, Lorivan, Lorpam, Lorvin, Lotweet, Nexlor, Norpose, Olraz, Trapex, Urpam, Zelor, Zepatrac, Zepnap

Similar Products:
Adalat, Uroxatral, Ultram, Luvox, Glucophage, Lodine, Myambutol

Also known as: Lorazepam

Description

Biolar tablets should be taken in the way your doctor prescribed them. Don’t take more or less Biolar than prescribed without first talking with your doctor.

Timing

Biolar is usually taken two or three times daily. These doses are usually spread out at equal intervals. However, when Biolar is used for insomnia, it’s usually taken just once at bedtime.

Taking Biolar with food

You can take Biolar with or without food. If it upsets your stomach, try taking it with food to help decrease this side effect.

Can Biolar be crushed?

Yes, Biolar can be crushed. Some Biolar tablets may also be split. If you’d like to split your tablets, ask your pharmacist if it’s safe to do so.

Dosage

ake this medication by mouth with or without food as directed by your doctor. The dosage is based on your medical condition, age, and response to treatment.

If directed by your doctor, use this medication regularly in order to get the most benefit from it. To help you remember, use it at the same time(s) each day.

Overdose

In cases of a suspected Biolar overdose, it is important to establish whether the patient is a regular user of Biolar or other benzodiazepines, since regular use causes tolerance to develop. Also, one must ascertain whether other substances were also ingested.

Signs of overdose range through mental confusion, dysarthria, paradoxical reactions, drowsiness, hypotonia, ataxia, hypotension, hypnotic state, coma, cardiovascular depression, respiratory depression, and death.

Early management of alert patients includes emetics, gastric lavage, and activated charcoal. Otherwise, management is by observation, including of vital signs, support and, only if necessary, considering the hazards of doing so, giving intravenous flumazenil.

Patients are ideally nursed in a kind, nonfrustrating environment, since, when given or taken in high doses, benzodiazepines are more likely to cause paradoxical reactions. If shown sympathy, even quite crudely feigned, patients may respond solicitously, but they may respond with disproportionate aggression to frustrating cues. Opportunistic counseling has limited value here, as the patient is unlikely to recall this later, owing to drug-induced anterograde amnesia.

Storage

Store Ativan at room temperature away from moisture, heat, and light.

Keep track of the amount of medicine used from each new bottle. Biolar is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription.

Side effects

The most common side effects associated with Biolar are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

The additive central-nervous-system effects of other drugs, such as phenothiazines, narcotic analgesics, barbiturates, antidepressants, scopolamine, and monoamine-oxidase inhibitors, should be borne in mind when these other drugs are used concomitantly with or during the period of recovery from Biolar Injection.

Extreme caution must be used when administering Biolar Injection to elderly patients, very ill patients, or to patients with limited pulmonary reserve because of the possibility that hypoventilation and/or hypoxic cardiac arrest may occur. Resuscitative equipment for ventilatory support should be readily available.

When Biolar injection is used IV as the premedicant prior to regional or local anesthesia, the possibility of excessive sleepiness or drowsiness may interfere with patient cooperation in determining levels of anesthesia. This is most likely to occur when greater than 0.05 mg/kg is given and when narcotic analgesics are used concomitantly with the recommended dose.

As with all benzodiazepines, paradoxical reactions may occur in rare instances and in an unpredictable fashion. In these instances, further use of the drug in these patients should be considered with caution.

There have been reports of possible propylene glycol toxicity (e.g., lactic acidosis, hyperosmolality, hypotension) and possible polyethylene glycol toxicity (e.g., acute tubular necrosis) during administration of Biolar Injection at higher than recommended doses. Symptoms may be more likely to develop in patients with renal impairment.

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An improved breast irradiation technique using three-dimensional geometrical information and intensity modulation. The treatment and reuse of wastewater in the textile industry by means of ozonation and electroflocculation. The interpretations of specific features of the Swiss cheese model varied considerably among quality and safety professionals. Cell and molecular analysis of long-term sensitization in Aplysia. A systematic literature review identified qualitative studies of issues important to older people near the end of their lives, to develop a model of the illness experience near the end of life based on the views of older people. Evaluation of the epidemiological importance of classical swine fever infected, E2 sub-unit marker vaccinated animals with RT-nPCR positive blood samples. We describe 1 unusual complication after MIRPE and 1 life-threatening bleeding during removal of the pectus bar.

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This article has provided evidence that children with chronic disorders of all kinds are at increased risk for psychosocial disturbances. These results justify further investigation into the role of teicoplanin for the treatment of serious infections caused by S. The effect on allograft survival of the transplantation of kidneys from living donors without the previous initiation of long-term dialysis is controversial. The Cox proportional model was used to analyze the risk factors in prognosis of patients. Residency and activation of myeloid cells during remodeling of the prepartum murine cervix. Recent candidate molecular markers: vitamin D signaling and apoptosis specific regulator of p53 (ASPP) in breast cancer. Before and during hypotension, we evaluated blood flow in the anterior spinal cord artery by determining the pulsatility index (PI) and resistance index (RI) using power Doppler ultrasonography. Studies with muscle cells from controls and a patient with the cerebro-hepato-renal (Zellweger) syndrome.

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Alcohol as a factor precipitating aggression and conflict behaviour leading to homicide. Patients with concomitant pathology (bronchicial asthma, chronic bronchitis, sinusitis, etc.) were found to have changes in the systemic immunity. In conclusion, these results indicate that the active T rosette MLC is a rapid approach (2 hr) to evaluate HLA-D-DR differences without influence by HLA-A,-B, or -C. A previously healthy 66-year-old women presented with onset of general weakness, shortness of breath and significant weight loss. These results suggest potentially promising performance of S-SIBS-coated stent in human clinical applications of coronary stenting. On the basis of the phase diagram, particulate and porous membranes, dominated by crystallization and liquid-liquid demixing, respectively, were prepared. Confirmation of target internalisation was achieved using a combination of fluorescent quenching and lipophilic membrane probes: R18 and FM 1-43. Subjects with Rett syndrome in this pilot sample were completely or partially dependent in all functional domains and significantly more so than children with Down syndrome. The ultrasound-mediated microbubble technique provides an effective noninvasive method for gene therapy.

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It also demonstrated that the sequences of the homoeologous Lrk genes evolved independently after polyploidization. In this study, we overexpressed type 1 sphingosine kinase (SPHK1), the enzyme that converts sphingosine to SPP, in order to examine more directly the role of intracellularly generated SPP in neuronal survival. Binding of reactive metabolites of CCl4 to specific microsomal proteins. The analog scintigram is a functional image with high sensitivity and low specificity. The objective of the present study was the unequivocal identification of its anti-sigma factor and of genes controlled by sigma(V). Eighty per cent of all creatinine values at 37 weeks gestation and over were 1.6 mg/100 ml or more. We have demonstrated a method for fabricating C60 overlayers with controlled spacing and chirality by reactive coadsorption with the aromatic molecule acridine-9-carboxylic acid (ACA). We found that in single trials the alpha oscillations after visual stimuli preserve their phase relationship with respect to the phase before the stimuli.

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The technique involves systemic administration of hematoporphyrin derivative (HpD), a photosensitizing compound that is preferentially retained by malignant cells and photoactivation of the neoplasm with red light (630 nm) to achieve selective destruction of cancer cells. Several treatments, including topical corticosteroids, photochemotherapy, ciclosporin, acitretin and etanercept 50 mg twice a day for 1 month, were ineffective or not tolerated. Lactoferrin in synovial fluid of patients with inflammatory arthritis. These were related to inadequate fixation of the ulna and to resection of the radial head which led to an increased strain on the ulnar fracture. In a group of patients who suffered from chronic ill health after an attack of acute infectious mononucleosis a disorder of T cell regulation was found. Their significance in an individual should be interpreted in the light of prior risk assessment based on maternal age and results of any first-trimester screening tests.

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We present a case of a 9-month-old boy diagnosed with both hepatoblastoma and neurofibromatosis type 1. We use molecular dynamics to simulate experiments where a symmetric binary fluid mixture (AB), confined between walls that preferentially attract one component (A), is quenched from the one-phase region into the miscibility gap. We have previously shown that lysyl oxidase (LOX) mRNA is up-regulated in invasive breast cancer cells and that catalytically active LOX facilitates in vitro cell invasion. Cells such as ataxia-telangiectasia mutated-deficient fibroblasts and U2OS cells, in which the early G2/M checkpoint after treatment with low concentrations of etoposide has been lost, executed mitosis with etoposide-induced DNA double-strand breaks, and 2-color FISH signals located on either side of the MLL gene were segregated in the postmitotic G1 phase. However, preimmersion of similarly patterned surfaces in water for 2 h prior to protein incubation was found to dramatically improve the protein-resistant properties of the comb polymer regions. Regulation of the rpsU-dnaG-rpoD macromolecular synthesis operon and the initiation of DNA replication in Escherichia coli K-12. We have previously shown that she is not able to perform a shape-matching task for stimuli presented to different hemifields. Vitamin D (VD) and estrogen deficiencies impair Ca absorption and bone mineralization, and the relevance of the interaction between these factors has not been fully understood. Within this maximum lamictal dose per day pilot study, we show for the first time that there is a correlation between certain radionuclide content and time since death.A larger study is proposed to confirm these findings and possibly provide a calibration against which bones uncovered can be dated.

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A novel polarographic method for the determination of coenzyme Q(10) in beta-cyclodextrin (beta-CD) and iodinate system is proposed. Paediatric caudal extradural catheterisation: an evaluation of a purpose designed equipment set. The material is representative and has been corrected according to new legislation. Results showed that AAV1 was superior to serotypes 2, 5, 7, and 8 in its relative ability to express hASM, alleviate storage accumulation, and correct behavioral deficits. Medical errors in the care of patients who present with acute coronary syndrome (ACS)include errors in emergency department (ED) triage, such as the decision to send home a patient who presents with ACS or to hospitalize a patient who does not have ACS to the cardiac care unit (CCU), and errors in treatment, such as the failure to promptly use reperfusion therapy for patients who present with ST-elevation acute myocardial infarction(AMI). The number of ED patients differed according to bed size, nurse staffing, residency training program, and the availability of emergency care-related equipment of the hospital. Progressive disseminated disease has been documented in the second patient despite postoperative adjuvant chemotherapy with combined cis-platinum and epipodophyllotoxin, and combined vincristine, cyclophosphamide, doxorubicin and dimethyl-tri propecia 90 day supply cost -azeno imidazole carboxamine. While a high CGA before treatment was found as an unfavorable prognostic determinant, a high ProGRP conferred a survival advantage.

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Effect of separate factors on the achievement of medical students in the lower courses. Amongst the investigated approaches, preincubation of the detection antibody with labeled anti-species antibody turned out to be most suitable under our conditions. In this prospective study, our aim was to investigate the CSF PSA levels and CSF/Serum PSA ratios in patients with prostate cancer with lower spine metastasis. Lateralisation of sound in temporal-lobe epilepsy: comparison between pre- and postoperative performances and ERPs. The extents of current inhibition as well as the time constant of current decay upon addition of the blocker to the test solution were dependent on agonist concentration, pointing to a competitive inhibition. In only one child, there was ankylosis of the hip and the end of treatment, the others having less sequelae of returning completely to normal. Transfusion-associated graft versus host disease postcardiac surgery. Bone marrow mesenchymal stem cells in myelodysplastic syndromes: cytogenetic characterization.

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The degree of right ventricular visualisation remained essentially unchanged in an early postoperative study (four to 60 days), though a decrease in right ventricular cavity size was noted in patients with right ventricular volume overload. Rapid, large-scale micropropagation of a Rheum rhaponticum (rhubarb) breeding line, selected for the absence of autumn dormancy, produces changes typical of somaclonal variation. The trace element nutrient selenium (Se) discharges its well-known nutritional antioxidant activity through the Se-dependent glutathione peroxidases. Inhibitors of von Willebrand factor prolong the bleeding time and impair ristocetin-induced platelet aggregation. The fractions were tested for immunoreactivity in human chorionic gonadotropin (hCG), hCG-beta-subunit and alpha-subunit radio-immunoassay systems. The use of rhenium or indium radiolabels for therapy may provide a new approach to GRP/bombesin expressing tumours. The identification of asbestos bodies in tissue sections is an indicator of past exposure to longer asbestos fibers. Small amounts of proteins with electrophoretic migration of tubulin and actin remain in neurofilament isolates. From our yeast two-hybrid screen, we found that four and a half LIM domains 2 (FHL2) could bind to the C-terminal half of HIPK2. Rat hepatocytes were isolated by in situ collagenase perfusion and primary culture, and pretreated with various concentrations of PKC agonist phorbol myristate acetale (PMA) and inhibitor chelerythrine for 20 minutes.

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A brief gun-safety counseling session supported with written information along with a gun lock giveaway resulted in significant improvements in safe gun storage behaviors. Embolization of central venous devices, such as infusion catheters, ventriculo-atrial drains for hydrocephalus or intracardial pacemaker leads, may cause fatal secondary complications. Analysis of the secondary structure of the wild-type, mutant, and pseudorevertant LamB signal sequences suggests that the secondary mutations restore export by allowing the formation of a stable alpha-helical conformation in the central, hydrophobic region of the signal sequence. Effects of mechanical stress on Anammox granules in a sequencing batch reactor (SBR). During chondrogenic differentiation of hMSCs, the genes for collagen 3alpha1, 9alpha2, 9alpha3, 10alpha1, 11alpha1 were activated, collagen 4alpha1 and fibromodulin inactivated and the genes for Col 1alpha1, biglycan und chondroadherin constantly expressed. Weight regain following LSG may require conversion to RYGBP or DS. The cytoskeleton is bound to the transmembrane proteins: by ankyrin to the internal segment of protein band 3, and by protein 4.1 to a glycoprotein named glycoconnectin. The advantage of using JJ ureteral stent during pregnancy in case of ureteral obstruction is shown two clinical observations. TIME offers a systematic approach to wound healing, which involves eliminating non-viable tissue, controlling infection, restoring moisture balance and promoting epithelial advancement. Slot blot results showed that apoA-I mRNA level increased at the end of the 1st week in the small intestine.

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This may inform the process of case selection for ICD therapy on an individual basis, although no single measurement provides sufficient reassurance to obviate device implantation if otherwise clinically indicated. Neuronal death was identified in semithin sections and with the electron microscope. The five deaths were due to pheumonia (two), innominate artery rupture missed one dose of clozapine (two), and pulmonary embolus (one). Scanning electron microscopic study of different hair types in various breeds of rabbits. Mathematical modeling and analysis of the flocculation process in chambers in series. The use of Ginkor Fort in the program of multimodality rehabilitation treatment of CYI patients with edematous syndrome. The ocular manifestations of sarcoidosis are diverse and include dry eyes due to lacrimal gland involvement, uveitis and optic nerve disease. The relationship between correction of hyponatraemia and the development of central pontine myelinolysis (CPM) remains controversial.

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Culture of monocytes with AGE-beta(2)m did not alter membrane expression of Fas or Fas ligand. The P terminal vector in lead V1 of the electrocardiogram in cor pulmonale. Proteolysis of D-EA virions by endocytic protease cathepsin L occurred with faster kinetics than proteolysis of wild-type T3D virions. The high hydrophobicity of the TM1 domain of L, but not of S, was shown to be cleocin topical cost essential for virus infection at a step downstream of receptor binding and virus internalization. This study demonstrates that the nitrosourea analogues act as immunomodulating agents and reinforces their interest as antineoplastic drugs since they can stimulate nonspecific effector mechanisms known to play a role in resistance against tumors. Sealing technologies using low-viscosity fluids are advantageous in this context since they potentially reduce the necessary injection pressures and increase the radius of influence around injection wells. Trisomy 12 is one of the most common chromosomal abnormalities in B-cell chronic lymphocytic leukemia (CLL).

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