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Bitrim (Trimethoprim)

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Bitrim (generic name: Co-trimoxazole; brand names include: Septra / Ciplin / Septrin) is a combination of two antibiotics (trimethoprim and sulfamethoxazole) used to treat a wide variety of bacterial infections.

Other names for this medication:
Altavit, Anitrim, Bactricid, Bactrimel, Baktar, Balkatrin, Bitrim, Broncoflam, Cosat, Cozole, Doctrim, Drylin, Editrim, Epitrim, Eusaprim, Infectrim, Kemoprim, Lagatrim, Nopil, Omsat, Primazole, Purbac, Servitrim, Suftrex, Sulfamethoxazolum, Sulotrim, Sumetoprin, Suprim, Trimethazol, Trisulin, Urisept

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Also known as: Trimethoprim


Bitrim is effective in a variety of upper and lower respiratory tract infections, renal and urinary tract infections, gastrointestinal tract infections, skin and wound infections, septicaemias and other infections caused by sensitive organisms.

Each Bitrim tablet contains 80 mg trimethoprim and 400 mg sulfamethoxazole.

Each Bitrim DS (double strength) tablet contains 160 mg trimethoprim and 800 mg sulfamethoxazole.


This medication is given by injection into a vein as directed by your doctor. It is given by slow infusion over 60 to 90 minutes. Dosage is based on your medical condition, weight, and response to treatment. If you are giving this medication to yourself at home, learn all preparation and usage instructions from your health care professional. Before using, check this product visually for particles or discoloration. If either is present, do not use the liquid. Learn how to store and discard medical supplies safely. Drink plenty of fluids while taking this medication to lower the unlikely risk of kidney stones forming, unless your doctor advises you otherwise. Antibiotics work best when the amount of medicine in your body is kept at a constant level. Therefore, use this drug at evenly spaced intervals. Continue to use this medication for the full time prescribed, even if symptoms disappear after a few days. Stopping the medication too early may allow bacteria to continue to grow, which may result in a return of the infection. Tell your doctor if your condition persists or worsens.


Often, no treatment is needed for an antibiotic overdose. Usually, you'll need to watch for stomach upset and possibly diarrhea. In those cases, you should give extra fluids.


Store at room temperature between 20 to 25 degrees C (68 to 77 degrees F) away from moisture, light and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

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The most common side effects associated with Bitrim are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of sulfamethoxazole and trimethoprim combination in the elderly. However, elderly patients are more likely to have a folate deficiency, age-related kidney or liver problems, and may be more likely to experience unwanted side effects (eg, severe skin rash, increased potassium in the body, or problems with blood clotting or the immune system). There may be an adjustment in the dose for elderly patients receiving sulfamethoxazole and trimethoprim combination.

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Inverted ratio of inducer to suppressor T-lymphocyte subsets in drug abusers with opportunistic infections. We performed a subgroup analysis of the The CLopidogrel plus Aspirin for Infarction Reduction (CLAIR in acute stroke or transient ischemic attack patients with large artery stenosis and microembolic signals) study of only patients with intracranial occlusive disease, excluding those with extra cranial disease. CpG island hypermethylation in progression of esophageal and gastric cancer. A proportion of macrophages showed a DNA content more than occurs in diploid cells, which could indicate a future division. The effects of temperature and ionic strength on HeLa cell aggregation, and of surfactants on the electrophoretic mobility of HeLa cells and the release of sialic acid from their surfaces by neuraminidase, were also examined.

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This review summarizes the current evidence for the existence of human breast stem cells and the pathways involved in their regulation, and discusses how the disruption of these pathways may result in the generation of a population of cells with the capacity for unlimited self-renewal. Suprapubic compared with transurethral bladder catheterization for gynecologic surgery: a systematic review and meta-analysis. The effects of angiopoietin-1 and -2 on tumor growth and angiogenesis in human colon cancer. The eigenvalues are expressed in terms of the zeros of Bessel functions of integer order. Growth in Chilean infants with chromosome 22q11 microdeletion syndrome. The aromaticity of the spacer decreases the strength of the exchange coupling constant. Excess mortality has proven to be a useful epidemiologic tool for influenza surveillance in the temperate zone.

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FT-IR, FT-Raman, NMR studies and ab initio-HF, DFT-B3LYP vibrational analysis of 4-chloro-2-fluoroaniline. Entrepreneurship in continuing dental education: a dental school perspective. We have screened a cohort of 11 women with diploid HMs with biparental contributions to the molar genome with regard to mutations in NLRP7, NLRP2, the NLRP gene most homologous to NLRP7, and C6orf221. Perceived barriers to the implementation of a baby friendly initiative in Jeddah, Saudi Arabia. H2B Tyr37 phosphorylation excluded binding of the transcriptional coactivator NPAT and RNA polymerase II and recruited the histone chaperone HIRA upstream of the Hist1 cluster. Failure of normal fusion between the AV node primordia and AV bundle can result in a variety of junctional anomalies including congenital heart block. Secondary bone grafting in cleft palate: a follow up of 145 patients.

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We are in the midst of a pandemic of obesity, which is complicating the care of patients with coronary artery disease (CAD). We conclude that valvulotomy within in situ vein bypasses can be successfully performed using a 1.5-mm laser hot-tip probe at 14 W power, with patency of the grafts demonstrated at 6 weeks. The objective of the study was to investigate the rates of mental disorder among women in prison in Victoria, and to compare with community rates. It is part of the chapter on cardiovascular, pulmonary, and cancer rehabilitation in the Self-Directed Physiatric Education Program for practitioners and trainees in physical medicine and rehabilitation. A set of case studies and preliminary user studies have been conducted with real graphs containing thousands of vertices, which provide supportive evidence about the usefulness of PIWI in community related tasks.

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We herein identified the p120 component as the protooncoprotein Cbl and the first steps associated to its activation. We report a very rare tongue localization in a 22-year-old white woman. Histopathology revealed hyperplastic arteriolosclerosis with intimal calcification contributing to ischemia. Survival prediction in portacaval shunts: a computerized statistical analysis. The absorption step of folic acid was identical in the two groups, while deconjugation of pteroyl-L-glutamyl-gamma-L-glutamyl-gamma-L-glutamic acid was significantly decreased in the patients with progressive systemic sclerosis. This article describes common primary (idiopathic) and secondary forms of hypogammaglobulinemia and how to evaluate and manage them. Parasitic worms: strategies of host finding, recognition and invasion.

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Clarification of turbid waters was effective, but filtration through a cloth is necessary to prevent flocculated sediment from entering the canteen. The circumstances of an accident as a misleading factor in therapeutic management. Outcomes from surgical repair are associated with high mortality. The relationship between amphetamine antagonism and depletion of brain catecholamines by alpha-methyl-p-tyrosine in rats. It is thought that this is mainly due to the conflicting information on the mass media and to the individual attitude (formed by cultural, educational and environmental factors), that is, one external factor and another personal factor. The other calculated low-frequency mode corresponds to the puckering motion coupled with the ring twisting mode and its ground state frequency has been observed at 119 cm(-1) and 111 cm(-1) from SVL spectra. Parameters describing the haemodynamic effect of PED and NF were calculated and were different according to the type of device used.

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The physical characterization of mutations that abolished coronatine production indicated that at least 30 kb of pPT23A DNA are required for toxin synthesis. Results confirmed that irradiation of male germ cells cause genetic effects which could be transmitted to the offspring. Educational intervention for patients with head and neck cancer in the discharge phase. Laboratory method for fermentation of meat and poultry sausages in fibrous casings. Idiopathic sclerosing encapsulating peritonitis (or abdominal cocoon) is a rare cause of small bowel obstruction, especially in adult population. The successful grafting of PMPC on the Fe(3) O(4) nanoparticles surface was ascertained from the FTIR analysis. Transfer of constructs containing different pax gene combinations into a paxilline negative deletion derivative of Penicillium paxilli demonstrated that just four proteins, PaxG, a geranylgeranyl diphosphate synthase, PaxM, a FAD-dependent monooxygenase, PaxB, a putative membrane protein, and PaxC, a prenyl transferase, are required for the biosynthesis of paspaline. In the thirteen other cases, the average follow up was four years. Surface modification of mesoporous, macroporous, and amorphous silica with catalytically active polyoxometalate clusters. We show that FDG-PET/CT is complementary to TAP-CT and of special interest in the diagnosis of local relapses.

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Stimulation of erythrocyte phosphatidylserine exposure by chlorpromazine. Cloned human T-cell lines with allospecific or natural killer-like cytotoxicity. The symptoms, sign, neuroimaging were analyzed and related literatures were reviewed. Proteins that interact with and regulate this essential enzyme are of great interest. Concurrent infection with human immunodeficiency virus (HIV) may accelerate the progression from cirrhosis to HCC. A retrospective analysis was performed of 101 consecutive patients who received chemoradiation and surgery for GEJ carcinoma between 1992 and 2001. The combination of knockdown studies and pharmaceutical inhibition in preclinical models demonstrates that FGFRs are attractive targets for therapeutic intervention in cancer. Three dimensional tracking of exploratory behavior of barnacle cyprids using stereoscopy. Quali-quantitative and temporal values are reported in the light of which we can affirm that conservative treatment enables the patient to lead an almost normal life, as well as returning to work, with a reduced risk of complications. Hyperoxic-induced hypercapnia in stable chronic obstructive pulmonary disease.

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Almost one child in twenty with trisomy 21 will develop spontaneous dislocation of the hip between learning to walk and the age of 10 years. CEA levels greater than 10.0 ng/ml after therapy correlated with significantly shortened survival. Behavioral responses evoked by periodic sensitization and activation of C nociceptors innervating the vector-treated skin area revealed a substantial and long-lasting (at least 20 weeks) antihyperalgesic and analgesic effect limited to the areas to which the virus was applied. The incidence, mechanisms of injury, and reparative procedures were discussed for each type of procedure. The author considers that the AMDP scale so modified is superior to other classical somatic scales, but deplores that functional symptoms are confused with psychopathological symptoms, neurological symptoms, toxic signs, general examination signs and even laboratory tests in the original scale. Studies that have attempted to identify these genes have met with limited success. aeruginosa raising the possibility of cross-talk with other related bacterial species which occupy similar ecological niches. Periodically stepped NiO(100) surfaces were prepared and characterized with low-energy electron diffraction (LEED), Auger electron spectroscopy (AES), X-ray photoelectron spectroscopy (XPS), and temperature-programmed desorption (TPD). Dissolved concentrations were determined for Fe, Mn, Al, Cu, Zn, La, U, Th, Cd and As in a wetland and its recipient stream to reveal the effect of seasonal changes in environmental conditions on the cycling and transfer of trace elements at the transition between terrestrial and aquatic ecosystems. denitrificans was grown on glucose with dialysis, addition of 5 x 10(-4)m pyruvate inhibited growth.

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The effect of highlight and object colors on perception of glossiness was examined. Comparison of Escherichia coli, Saccharomyces cerevisiae, Pichia pastoris, Spodoptera frugiperda, and COS7 cells for recombinant gene expression. Laparoscopic resection is the method of choice in the treatment of patients with nontumoral affection of colon. The information obtained was compared to previous data series available for the area affected by the spill. This has prompted newer searches for immune function and regulation in other systems. The T cell responses in these animals are comprised of Th2 cells in the lymph node and anergic Th1 lymphocytes in the spleen. Daily Pco-2 and pH fluctuations in pulmonary emphysema with carbon dioxide retention. TNFalpha treatment induced DCs maturation and up-regulation of CD80, CD86 and CD83. The paranoid participants also gave increased estimates of control on the contingency judgment task. The primary prevention of cardiovascular disease involves using the Framingham risk score to identify high risk patients and then prescribe preventive treatments.

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The present work was designed to investigate the effects of ketanserin on BRS within the nucleus tractus solitarus (NTS) and the rostral ventrolateral medulla (RVLM). Of the three species studied, Desulfobacter postgatei was the least successful competitor for limiting amounts of sulfate. Decontamination of of aromatic amine cancer-suspect agents on concrete, metal, or painted surfaces. Transient-state analysis of metabolic fluxes in crabtree-positive and crabtree-negative yeasts. Sequence changes in coliphage lambda mutants affecting the nutL antitermination site and termination by tL1 and tL2. The reliability of histological diagnosis of squamous epithelial changes was tested by letting 13 pathologists read 1,001 consecutive cervical biopsies twice. It is thought that delayed mobilization aids brain re-expansion thereby reducing the risk of recurrence. albicans clinical strains using hyphae is feasible, as this has been previously shown with blastospores. Role of tumor necrosis factor alpha (TNF-alpha) and interleukin-10 in the pathogenesis of severe murine monocytotropic ehrlichiosis: increased resistance of TNF receptor p55- and p75-deficient mice to fatal ehrlichial infection. Our findings for the physically unlinked LGALS2, invite further study of LGALS2 specifically and the LTA pathway generally for their influence on glucose-insulin regulation.

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Non-colony type monolayer culture of human embryonic stem cells. We have developed a method that can identify switching dynamics in time series, termed the improved annealed competition of experts (IACE) algorithm. In the traumatically injured mice SC, NSC grafting improves motor recovery. Endogenous carbon monoxide modulates canine HPV only in the absence of nitric oxide. Twenty control subjects, 12 insulin treated and 10 non-insulin treated diabetics were studied. A 2-day-old newborn was admitted to the hospital because of a mass in the interscapular region. Here sumycin drug classification we identify the Cdk1 substrate, Ect2, as a central regulator of mitotic rounding, thus uncovering a link between the cell-cycle machinery that drives mitotic entry and its accompanying actin remodeling.

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Delirium and dementia in the peri-operative management of elderly surgical patients. Congenital megacolon associated with enterocolitis and hypoproteinemia. Content of cytochrome P-450 was decreased in rat liver microsomes, pretreated with phenobarbital, after incubation with acrylamide, methyl methacrylate and butyl methacrylate in presence of NADPH in vitro. To compare spectral and complexity characteristics of the EEG in a unique case of subcortical infarct to those seen in healthy controls. Two women (aged 72 and 78 years) developed hepatitis due to clometacine. Absence of generalized immunosuppression in C57BL/6J mice implanted with Lewis T241 fibrosarcoma or Lewis lung carcinoma. Collectively, these results are consistent with a critical role for CD36 dephosphorylation through Src family kinase activation in regulating IRBC adhesion to vascular endothelium. Morphometry disclosed a substantial shift of the mast cell population towards light, heparin-free cells within one minute after alpha-thrombin administration. CRT is defined as a mental health intervention involving physical restraint and is used in adoptive or foster families with the intention of increasing emotional attachment to parents.

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The indications for HIFU have recently been expanded to include its use both as a primary therapy for organ-confined prostate cancer as well as for local recurrence of prostate cancer, following radiation therapy. Likewise, patterns of within-sex shape variation were similar in the two species, particularly in males: relative elongation of the male head capsule, antenna, and legs was associated with reduced head capsule width and wing length, but was nearly independent of variation in thorax length. Over a period of 14 1/2 years, 26 instances of amoebic perforation of the bowel occurring in 25 patients were treated surgically. This A-E2-induced and--sustained E2U deficiency was not accompanied by similar changes in plasma and tissue progesterone (P), since P decreased similarly in the control and A-E2--treated rats in preparation for parturition. The results show influence of internal muscle dynamics on muscle control histories vis a vis muscle forces.

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The main outcome measure was FSHr sequencing and in vitro evaluation of the variation of cAMP production of FSHr mutants. tianshanense genomic expression library in Escherichia coli, coupled with a sensitive AHL detector, uncovered a LuxI-type synthase, MrtI, and a LuxR-type spironolactone amiloride equivalent dose regulator, MrtR, in M. Successful revascularization of the heart muscle improved the mechanical function of the left ventricle. Some regard drug-eluting metal stents as the final technologic advancement in the treatment of coronary artery disease, others consider the future development of degradable, drug-eluting stents as the next logical step. After a trivial injury, a 16-year-old girl had pain, disability and oedema in her right arm.

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Authors assume that there is a correlation between the damage of the organella and the detoxication of the toluene by hepatocytes. At testing, the patient group showed an overall decrease in depression severity symptom load as measured on the Hamilton Depression Rating Scale (HDRS), but with variable symptom load. Idiograms of yak (bos grunniens), cattle (bos taurus) and their hybrid. Lectin histochemistry of Jacalin (Artocarpus integrifolia) and peanut agglutinin (PNA), specific lectins for galactosyl (beta-1, 3) N-acetylgalactosamine (galactosyl (beta-1, 3) GalNAc), was applied to the gustatory epithelium of the adult rat. Splenic alterations during mammary tumorigenesis: diverse effects on different immune parameters. The benefits of long-term inhaled glucocorticosteroid treatment in children with asthma outweigh the risks. Based on these, it is our opinion that for now the management and control of trypanosomosis will continue to depend on proper usage of the few available trypanocides, especially strategic deployment of the sanative drugs in order to reduce the development of drug resistance, in addition to the continued use of environmentally friendly vector control programmes such tsetse trapping. Evidence of a neural loop involved in controlling spermathecal contractions in Locusta migratoria.

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Over the last few years, the posterior cruciate ligament (PCL) has taken over from the anterior cruciate ligament (ACL) as the new challenge in knee diagnosis and treatment. The study examined the distribution and correlates of differential levels of self-reported anomalous experience in a British sample of 1,000 individuals. Relationships between feeding and locomotion behaviors after central administration of CRF in chicks. Effect of anti-CD 20 antibody rituximab in patients with post-transplant lymphoproliferative disorder (PTLD). Uncertainty of Measurement: A Review of the Rules for Calculating Uncertainty Components through Functional Relationships. Weight gain interventions, including behavioral modifications, show promise in controlling or reducing weight in patients treated with antipsychotics. In addition, a discussion of the advantages and limitations of this technique is provided. Due to rapid enlargement of the kidney, we first suspected that she had diffuse renal invasion of anaplastic carcinoma or lymphoma of the kidney. Mortality and morbidity from colorectal or lung cancers were not associated with folate levels. The results lead one to question when and how emotional engagement might occur in a professional ethical situation.

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Mortality in relation to the functional capacities of people with disabilities living at home. Stapled and sewn anastomoses have similar primary and secondary patency and flow characteristics, with minimal operative time differences. The experimental neurogenic inflammation model represents a simple procedure to obtain preliminary information on well characterized receptortargeted drugs. Hepatitis B e antigen elimination or seroconversion was achieved in 3 survivors. Cephalofacial characteristics of North American Black individuals with sickle cell disease. OCT is increasingly being utilized to further our understanding of intracoronary pathology and the effects of therapies both pharmacologic and procedural on the coronary vasculature. Four days later she developed vomiting with serum sodium 119 mEq/L. Ultrasonic nebulization of water and mucoevacuant solutions in patients with obstructive aristocort dosage lung disease: volumetric and ventilatory responses to acute administration.

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FO significantly reduced the severity of ulceration in gastric ulcers induced by aspirin, cold-restraint stress (CRS), alcohol, and pylorus ligation. The influence of photon scattering and attenuation was dependent on regions. Airborne fungi and bacteria in child daycare centers and the effectiveness of weak acid hypochlorous water on controlling microbes. Accurate diagnosis was achieved in all 3 living patients by echocardiography, angiocardiography, and magnetic resonance imaging. AcrySof Natural SN60AT versus AcrySof SA60AT intraocular lens in patients with color vision defects.

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n-Butyl benzyl phthalate promotes breast cancer progression by inducing expression of lymphoid enhancer factor 1. Reactive oxygen species (ROS) are implicated in the pathophysiology of a number of vascular disorders, including atherosclerosis. Although experimental models of restenosis may not reflect restenosis in humans in all details, we suggest that a NO-releasing aspirin derivative could be an effective drug in reducing restenosis following PTCA, especially in the presence of hypercholesterolemia and/or gastrointestinal damage. EMAP cytokine expression in developing retinas of normal and retinal moduretic 5 mg 50 mg compresse degeneration (rd) mutant mice. Two papers in this issue of Immunity demonstrate that PKC-dependent phosphorylation of CARMA1 is the critical molecular link that controls the activation of the IKK signalosome and NF-kappaB. This may participate in the mucosal infiltration by eosinophils in this disease. In some regions, this newly formed bone seemed to present interdigitations connecting to or entering into the particle surface.

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Diagnosis of occult scaphoid fracture with high-spatial-resolution sonography: a prospective blind study. Due to the linkage of retinal to the protein, it seems colored and has numbers of versatile properties. Germination and outgrowth of single spores of Saccharomyces cerevisiae viewed by scanning electron and phase-contrast microscopy. Effects of two glucocorticoids on milk yield and biochemical measurements in healthy and ketotic cows. To create a breast mound and nipple with projection and even pigmentation, the free-nipple-graft breast reduction technique is presented. Many patients with advanced head and neck cancer become unable to obtain sufficient nutrition and hydration orally, leading to considerable weight loss and compromised clinical outcomes. Menopause is an important life event that has not yet been well characterized among women with severe mental illness. AFXa levels were determined 4, 12 and 24 h after injection of certoparin.

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As a result, the application of risk assessment of diffuse pollution at the catchment level has been limited. The recombinant extracellular domain of human short RPTPbeta was used to immunize mice and generate monoclonal antibodies that selectively recognize RPTPbeta and bind to the antigen with low nanomolar affinities. The aim of this study was to determine the influence of debonding force direction in shear bond strength testing of orthodontic brackets in vitro. Within 18 h after settlement, the cells at the surface of the cell mass differentiate to pinacocytes. This article gives a short survey of the most important genetic alterations and their prognostic influence on the outcome of patients with plasma cell malignancies known to date. To compare the antibacterial effect between sodium fluoride and Galla Chinesis in bioflim model. The results were assessed radiologically and by histological studies. Pathology of delayed radiation brain damage: an experimental canine model. Guidelines recommend presumptive treatment of sexual contacts of individuals with syphilis at the point of care.

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