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Buconif (Nifedipine)

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Buconif is a calcium-channel blocker. It affects the amount of calcium found in your heart and muscle cells. This relaxes your blood vessels, which can reduce the amount of work the heart has to do. This medicine is used to treat chest pain caused by angina.

Other names for this medication:
Adalate, Antrolin, Aprical, Atanaal, Belnif, Buconif, Calcigard, Cardules, Chronadalate, Cobalat, Conducil, Conetrin, Coracten, Coral, Cordaflex, Corotrend, Depicor, Depin, Emaberin, Ficor, Menoprizin, Myogard, Nidicard, Nifcal, Nifebene, Nifedip, Nifehexal, Nifeslow, Nifical, Niften, Nipin, Nirena, Noviken, Oxcord, Pabalat, Pressolat, Siopelmin, Tensopin, Valni, Vasdalat

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Amoxil, Fulvicin, Mircette, Motrin, Alprostadil, Nizoral, Trandate, Claritin

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Also known as: Nifedipine


Nifedipine is used alone or together with other medicines to treat severe chest pain (angina) or high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled.

Nifedipine is a calcium channel blocker. It works by affecting the movement of calcium into the cells of the heart and blood vessels. As a result, nifedipine relaxes blood vessels and increases the supply of blood and oxygen to the heart while reducing its workload.

This medicine is available only with your doctor's prescription.


This section provides information on the proper use of a number of products that contain nifedipine. It may not be specific to Buconif OROS. Please read with care.

In addition to the use of this medicine, treatment for your high blood pressure may include weight control and changes in the types of foods you eat, especially foods high in sodium (salt). Your doctor will tell you which of these are most important for you. You should check with your doctor before changing your diet.

Many patients who have high blood pressure will not notice any signs of the problem. In fact, many may feel normal. It is very important that you take your medicine exactly as directed and that you keep your appointments with your doctor even if you feel well.

Remember that this medicine will not cure your high blood pressure, but it does help control it. You must continue to take it as directed if you expect to lower your blood pressure and keep it down. You may have to take high blood pressure medicine for the rest of your life. If high blood pressure is not treated, it can cause serious problems such as heart failure, blood vessel disease, stroke, or kidney disease.

Swallow the extended release tablet whole. Do not break, crush, or chew it. It is best to take this tablet on an empty stomach.

If you are taking the extended-release tablets, part of the tablet may pass into your stool after your body has absorbed the medicine. This is normal and nothing to worry about.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For treatment of chest pain or high blood pressure: For oral dosage form (capsules): Adults—At first, 10 milligrams (mg) three times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage form (extended-release tablets): Adults—At first, 30 or 60 milligrams (mg) once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 90 mg once a day. Children—Use and dose must be determined by your doctor.


If you overdose Buconif and you don't feel good you should visit your doctor or health care provider immediately.


Store at room temperature between 15 and 25 degrees C (59 and 77 degrees F) away from moisture and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Buconif are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of nifedipine in the elderly. However, elderly patients are more likely to have age-related kidney, liver, or heart problems which may require caution and an adjustment in the dose for patients receiving nifedipine.

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Studies with 51Cr-labeled T cells indicated that the low activity of intravenously transferred cells was due to an altered migration pattern. The studies also suggest that relatively less efficient convective transport with glucose as compared to hydrostatic pressure is neither a membrane phenomenon nor a characteristic of all osmotic pressure induced ultrafiltration. Differentiation of adipose tissue and muscle in hypophysectomized pig fetuses. A new ventilator: a combined minute volume divider and humidifier. RT-PCR analysis showed that the lower level of protein production was due to a reduction in RNA synthesis. Previous interventions (excisional biopsy, incomplete dissection) in the regional basin that drain a melanoma site prior to definitive surgical procedures significantly increase the risk of melanoma recurrence in the surgical field. The aim of this article is to illustrate the possibility of performing a cochlear implant with local anesthesia and sedation, the anesthesic technique and the advantages of that in comparison to a general anesthesia. Primordial germ cells comprise a privileged cellular class within the embryo charged with the elite task of maintaining species longevity. As results from numerical computations, an initial diversity of cultural features in a community has an essential influence on an evolution of social network. Both enhancement of GABAergic neurotransmission and antagonism of glutamatergic neurotransmission involving the NMDA receptor have been implicated in the acute effects of ethanol.

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Jump-land characteristics and muscle strength development in young athletes: a gender comparison of 1140 athletes 9 to 17 years of age. Testicular adrenal rest tumors (TART) are consequences of delayed diagnosis and/or undertreatment in patients with congenital adrenal hyperplasia (CAH). None of these metabolites revealed a splenotoxic potential comparable to that of aniline in studies with repeated or long-term administration to rats. Active video games as a form of exercise and the effect of gaming experience: a preliminary study in healthy young adults. This activity of ghrelin could play a potentially significant role in rapid restoration of homeostasis after food intake. The resolution and sensitivity of this technique may be of diagnostic significance.

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Death by undiagnosed perforated peptic ulcer: analysis of 31 cases. Infection and inflammatory pathways that mediate prematurity have also been implicated in neonatal developmental impairments. Parachute abnormality of mitral valve frequently occurs with left sided obstructive lesions though occasionally may occur as an isolated lesion. The submucous resection of septum by Killian is not appropriate as a primary correcting treatment, especially in case of traumatical tenormin medication septum deformities. HLA-A2.1 molecules were purified from detergent-solubilized human melanoma cells by immunoaffinity column chromatography and further fractionated by reversed phase high performance liquid chromatography. The Delphi method was applied to elicit and combine the judgments of a fifty member panel considered knowledgeable about the CME field. The Medicare Modernization Act of 2003 provides federal assistance to eligible beneficiaries by paying for their prescription medications. Smad3NS also formed complexes with Smad4 and translocalized into the nucleus. She complained of back pain but had fully intact neurological function. Incubation of omental vessels from normotensive pregnant women and myometrial vessels from nonpregnant women with plasma from women with preeclampsia had no effect on the endothelium-dependent relaxation observed.

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Western blot analysis and repair activity in extracts from levaquin dosage oral Ogg1(-/-) mice revealed that OGG1 was responsible for the efficient 8-oxoG removal from prenatal mice. It is suggested that in school-aged children, peer pressure to keep up with activities in school and play may attenuate the reduced activity sometimes seen in preschool and adult subjects as a response to restricted energy intake. Static signatures originate as handwritten images on documents and by definition do not contain any dynamic information. In Europe, VTE prophylaxis by LMWH is widely used in elderly medical patients without specific guidelines in this population. To test the hypothesis that patients with asthma who develop cough and wheezing after the use of beclomethasone aerosol would have a better tolerance for triamcinolone aerosol. Subjects in all three age groups performed better in FWB than in PWB.

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The two registrations involved in SISCOM are (1) between the ictal-interictal SPECT max dose iv enalapril images, which was shown to be the more critical, and (2) between the ictal image and MRI. Adaptation-by-rate and adaptation-by-orientation effects were observed on the amplitude of N170, and both were more pronounced for faces relative to characters. Apparently, skin cells may produce factors that inhibit the development of metatarsal bones. Metal-assisted unusual hydroxylation at the carbon atom of the triazine ring in dinuclear ruthenium(II) and osmium(II) complexes bridged by 2,4,6-tris(2-pyridyl)-1,3,5-triazine: synthesis, structural characterization, stereochemistry, and electrochemical studies. An optical sensor is presented which determines the position and one degree of orientation within a magnetic resonance tomograph. This initial increase was regularly followed by a depression of ICP in between 7--12 days after SAH.

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Base specific binding of deoxyguanylate and deoxycytidylate antibodies to double stranded DNA. The oil and certain active ingredients showed beneficial immunomodulatory properties, augmenting the T cell- and natural killer cell-mediated immune responses. A large dose dependent change in per cent of sulphadimethoxine bound to plasma proteins was shown. It is showed which fascination had exclusively biological and genetic explanations for the genesis of diseases and human attitude characteristics. Effects of short-term fenofibrate treatment on circulating markers of inflammation and hemostasis in patients with impaired glucose tolerance. Most basidia produce two basidiospores, each of which receives two of the four postmeiotic nuclei. Degradation of organic matter from black shales and charcoal by the wood-rotting fungus Schizophyllum commune and release of DOC and heavy metals in the aqueous phase.

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Atazanavir concentrations are decreased when tenofovir is co-administered. The resultant pathophysiologic phenomena and their clinical aspects are the consequences of this. The cytochrome P450 arachidonic acid epoxygenase metabolites are resolved, without the need for derivatization, by chiral-phase HPLC on a Chiralcel OJ column. Consent, competence, and confidentiality related to psychiatric conditions in adolescent medicine practice. Experimentally the approach is based on a stirred flow-through reactor containing gel entrapped enzymes. The NMR-based metabonomic analyses corroborated these results showing changes of metabolites associated with the above altered mechanisms. New randomized clinical trials are needed to further refine the place of this approach in the management of SCLC. The hybrid system consists of a commercially available membrane filter incorporated into a poly(dimethylsiloxane) (PDMS) casted device. Effects of treatment with dithiothreitol on the extraction, activity and purification of ox-kidney urate oxidase. Predisposition to gastric erosions in the rat: behavioral and nutritional effects of early maternal separation.

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Prospective studies have demonstrated the clinical utility of determining 6-thioguanine nucleotides to individualise immunosuppressive therapy with azathioprine not only in the field of transplantation, but also in inflammatory bowel disease. As a result, influenza morbidity in Severodvinsk was reduced 1.5-2 times in comparison with that in the neighboring control cities. We assess the feasibility of PACES data for surveillance, describe time-trends, and identify methods of sub-analysis which could improve performance. To provide an update on the handheld electronic resources for evidence-based practice (EBP) in the community setting. In the search of chemicals that arise from natural food source, allicin is one such ingredient from garlic that was discovered with the potential to provide beneficial effects to the cardiovascular system. At each visit the patients were classified as being either in good control (GC) or in poor control (PC), based on well-defined clinical, auxological and biochemical criteria.

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