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Cardem (Diltiazem)

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Cardem is an antihypertensive and vasodilating agent that works by relaxing the vascular muscle and reducing blood pressure. This is related to the long-term therapeutic effects, as lowering the blood pressure reduces the risk of fatal and non-fatal cardiovascular events, primarily strokes and myocardial infarctions.

Other names for this medication:
Altiazem, Angizem, Cardem, Cardiorex, Cartia, Coriem, Dilacor, Dilcardia, Dilcontin, Dilcor, Dilgard, Dilocor, Dilter, Diltia, Diltiaz, Diltiazem, Diltp, Dilzem, Heartil, Icidil, Ionozem, Kaizem, Masdil, Onzem, Tiamate, Tiazac

Similar Products:
Ativan, Zyloprim, Zofran, Requip, Mircette, Elocon, Aldara, Robaxin, Aceon, Zyprexa

Also known as: Diltiazem


Diltiazem is used alone or together with other medicines to treat angina (severe chest pain) or hypertension (high blood pressure). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled.

Diltiazem is a calcium channel blocker. It works by affecting the movement of calcium into the cells of the heart and blood vessels. As a result, diltiazem relaxes the blood vessels and increases the supply of blood and oxygen to the heart while reducing its workload.

This medicine is available only with your doctor's prescription.


This section provides information on the proper use of a number of products that contain diltiazem. It may not be specific to Cardem CD. Please read with care.

In addition to the use of this medicine, treatment for your high blood pressure may include weight control and changes in the types of foods you eat, especially foods high in sodium (salt). Your doctor will tell you which of these are most important for you. You should check with your doctor before changing your diet.

Many patients who have high blood pressure will not notice any signs of the problem. In fact, many may feel normal. It is very important that you take your medicine exactly as directed and that you keep your appointments with your doctor even if you feel well.

Remember that this medicine will not cure your high blood pressure, but it does help control it. You must continue to take it as directed if you expect to lower your blood pressure and keep it down. You may have to take high blood pressure medicine for the rest of your life. If high blood pressure is not treated, it can cause serious problems such as heart failure, blood vessel disease, stroke, or kidney disease.

Swallow the extended-release tablet, extended-release capsule, or tablet whole. Do not open, crush, or chew it. It is best to take the extended-release capsule on an empty stomach.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For chest pain: For oral dosage form (extended-release capsules): Adults—At first, 120 milligrams (mg) once a day in the morning. Your doctor may adjust your dose if needed. Children—Use and dose must be determined by your doctor. For oral dosage form (extended-release tablets): Adults—At first, 180 milligrams (mg) once a day, either in the morning or evening. Your doctor may adjust your dose if needed. Children—Use and dose must be determined by your doctor. For oral dosage form (tablets): Adults—At first, 30 milligrams (mg) four times a day before meals and at bedtime. Your doctor may increase your dose if needed. Children—Use and dose must be determined by your doctor.

For high blood pressure: For oral dosage form (extended-release capsules): Adults—At first, 180 to 240 milligrams (mg) once a day in the morning. Your doctor may adjust your dose if needed. Children—Use and dose must be determined by your doctor. For oral dosage form (extended-release tablets): Adults—At first, 180 to 240 milligrams (mg) once a day, either in the morning or at bedtime. Your doctor may adjust your dose if needed. Children—Use and dose must be determined by your doctor.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of diltiazem can be fatal.

Overdose symptoms may include slow heartbeat, weakness, chest pain, shortness of breath, or fainting.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Cardem CD dosage information

Side effects

The most common side effects associated with Cardem are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Studies in women suggest that this medication poses minimal risk to the infant when used during breastfeeding.

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Certain cases of acute leukemia in children with hyperleukocytosis in the peripheral blood and increased risk of development of uric acid nephropathy. Quasi-elastic neutron scattering experiments supplemented by molecular simulations. Systemic involvement of other organs, however, was excluded by bone scintigraphy, abdominal ultrasound, bone marrow aspiration and echocardiography. Particle sizing and biokinetics of interstitial lymphoscintigraphic agents. Use of a serological approach for prediction of Salmonella status in an integrated pig production system. The former is employed by lipophilic drugs and by molecules selectively transported by channels, pumps and carriers present in the plasma membrane.

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The present findings suggest close antigenic relationship of camels with pigs and ruminants. In parallel infections using inocula supplemented with an inducing 2 microM concentration of hemin chloride, hemin coadministration augmented the competitive advantage of the wild-type strain over the mutant. Addition of 1 mM MgCl2 to the medium prevented the total uncoupling of inner membranes and gave ADP:O values similar to those obtained with whole mitochondria from magnesium-deficient rats. The estimation of economic benefits of health effects through direct methods, such as contingent valuation, presents the problem of preference imprecision. Treatment was introduced sequentially across subjects and involved six thermal biofeedback treatment visits. At the end of this article, special issues in economic evaluation sumycin 500 mg price in uae studies are presented such as discounting, sensitivity analysis, incremental analyses and ratios.

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GRFdeltaC binds H-Ras.GTP in both pulldown assays from bacterial lysates and by coimmunoprecipitation from HEK293 cells. As a conclusion, assessment of endocrine disruption based on chemical analysis alone does not appear sufficient and further research into the spectrum of substances with potential endocrine activity as well as into additive or even synergistic effects in complex environmental samples is urgently needed. These normative data for three calcaneal QUS parameters will be useful for predicting fracture risk and determining diagnostic QUS criteria of osteoporosis in non-industrialized populations in South America and elsewhere. To evaluate the effect of combination of Nance and TPA on the use of MBT appliance to treat Class II division I malocclusion. In addition, they retained some ability to express the GFP transgene for at least 6 weeks after transplantation. A multidisciplinary renal osteoporosis clinic: a new role for the nephrology nurse.

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