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Cardon (Losartan)

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Cardon is used to treat patients with chronic heart failure when therapy with specific medicines called angiotensin-converting-enzyme inhibitors (ACE inhibitors, medicine used to lower high blood pressure) is not considered suitable by your doctor. If your heart failure has been stabilised with an ACE inhibitor you should not be switched to Cardon.

Other names for this medication:
Angilock, Angizaar, Arapres, Biortan, Cardon, Covance, Cozzar, Enromic, Hizaar, Lacine, Lakea, Loben, Losacar, Losan, Losardil, Losartic, Losazid, Losium, Lostad, Lozatan, Maxartan, Mozartan, Myotan, Ocsaar, Osartil, Psycholanz, Ranlozar, Rasertan, Repace, Resilo, Sanipresin, Sarvas, Sarvastan, Sarve, Sedeten, Simperten, Sortiva, Tacicul, Temisartan, Tensartan

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Also known as: Losartan


Cardon is indicated for the treatment of hypertension in adults and pediatric patients 6 years of age and older, to lower blood pressure. Lowering blood pressure lowers the risk of fatal and nonfatal cardiovascular (CV) events, primarily strokes and myocardial infarction. These benefits have been seen in controlled trials of antihypertensive drugs from a wide variety of pharmacologic classes including losartan.

Control of high blood pressure should be part of comprehensive cardiovascular risk management, including, as appropriate, lipid control, diabetes management, antithrombotic therapy, smoking cessation, exercise, and limited sodium intake. Many patients will require more than 1 drug to achieve blood pressure goals. For specific advice on goals and management

Cardon is indicated to reduce the risk of stroke in patients with hypertension and left ventricular hypertrophy, but there is evidence that this benefit does not apply to Black patients

Cardon is indicated for the treatment of diabetic nephropathy with an elevated serum creatinine and proteinuria in patients with type 2 diabetes and a history of hypertension. In this population, Cardon reduces the rate of progression of nephropathy as measured by the occurrence of doubling of serum creatinine or end stage renal disease


Usual Adult Dose for Diabetic Nephropathy:

Initial dose: 50 mg orally once a day Maximum dose: 100 mg orally once a day Comments: -If hypertensive patients with left ventricular hypertrophy or type 2 diabetic nephropathy patients require titration from initial dose, increase to 100 mg orally once a day. -Antihypertension is substantially present within 1 week but in some studies the maximal effect occurred in 3 to 6 weeks. Uses: -Treatment of hypertension. -To reduce the risk of stroke in patients with hypertension and left ventricular hypertrophy. -Treatment of diabetic nephropathy with an elevated serum creatinine and proteinuria (urinary albumin to creatinine ratio 300 mg/g or greater) in patients with type 2 diabetes and a history of hypertension.

Usual Adult Dose for Hypertension:

Initial dose: 50 mg orally once a day Maximum dose: 100 mg orally once a day Comments: -If hypertensive patients with left ventricular hypertrophy or type 2 diabetic nephropathy patients require titration from initial dose, increase to 100 mg orally once a day. -Antihypertension is substantially present within 1 week but in some studies the maximal effect occurred in 3 to 6 weeks. Uses: -Treatment of hypertension. -To reduce the risk of stroke in patients with hypertension and left ventricular hypertrophy. -Treatment of diabetic nephropathy with an elevated serum creatinine and proteinuria (urinary albumin to creatinine ratio 300 mg/g or greater) in patients with type 2 diabetes and a history of hypertension.

Usual Pediatric Dose for Hypertension:

6 Years or Older: Initial dose: 0.7 mg/kg orally once a day (up to 50 mg total) Comments: -May be given as a tablet or suspension. -Doses above 1.4 mg/kg (or 100 mg) daily have not been studied in pediatric patients.

Detailed Cardon dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children in a container that small children cannot open.

Side effects

The most common side effects associated with Cardon are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Drinking alcohol can further lower your blood pressure and may increase certain side effects of Cardon.

Do not use potassium supplements or salt substitutes, unless your doctor has told you to.

Avoid getting up too fast from a sitting or lying position, or you may feel dizzy.

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Determination of vitamin D 2 in gelatin-protected vitamin A acetate-vitamin D2 beadlets by high pressure liquid chromatography. This is contrary to the assumption that processes in the foetal membranes initiate the sequence of events leading to abortion or labour. Though the birds exhibited gross behavioral incoordination, visual stimulus control appeared unaffected. Microbiological processes in the different technological modes of flax retting. The magnetic-field-induced (MFI) chains become floppy after removal of the field, folding into three-dimensional (3D) coiled structures upon gentle agitation. Synovial accumulation of technetium labelled liposomes in rheumatoid arthritis.

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We also develop algorithms to optimize the JPEG2000 code stream for exponential and Laplacian rate distribution functions while maintaining compatibility with the JPEG2000 standard. The evolutionary emergence of the egalitarian syndrome is one of the most intriguing unsolved puzzles related to the origins of modern humans. Maximal voluntary isometric contraction force averaged 189 N (120 to 309 N), and showed a close relationship with total cross-sectional area of the brachial biceps muscle. The articular manifestations of periodic disease (familial Mediterranean fever). Further improvements in preoperative risk stratification, including advances in imaging technology, may help refine decisions regarding the extent of surgery and the use of neoadjuvant chemotherapy in these individuals. In the chronic stage, no significant differences were observed between the two sides. Method of calculation of energy loss in the apparatus for artificial respiration of different types.

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More than 3000 men and women, aged 40-64 years, from the French study: data from an epidemiological study on the insulin resistance syndrome (D.E.S.I.R.). We found no evidence to support the hypothesis that suckling reduces binding capacity of transcortin or increases unbound cortisol. Especially in their early phase of action carcinogens are strong inhibitors of cell proliferation. Effect of visual input on vestibular nystagmus in autistic children. The effects of quinestrol on hepatic function are similar to the effects of other estrogen derivatives. The method is able to process simultaneously several related chromatograms. The patient, a 9-year-old girl, came to our clinic with chief complaints of unconsciousness and left hemiplegia. Overexpression and specific depletion of PKA inhibit CE movements. Insertion sequences shared by Bordetella species and implications for the biological diagnosis of pertussis syndrome.

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The purpose of this study was to explore the relationship between two measures of empathy in older adults. The influence of rat suspension-hypokinesia on the gastrocnemius muscle. There is currently a paucity of instruments with established psychometric properties measuring severity of trauma exposure in disaster survivors. The level of accountability was very high, with less than 1 discrepancy in 10, for all the data collected. ATG were responsible of an early and long lasting impairment in CD4 cells. We studied 494 colon and rectal cancer patients to identify risk factors for nodal metastasis and evaluated the potential to predict nodal metastasis by either the logistic regression model or the Bayesian neural network model with built-in matrilysin. Moreover, a marked drop in the mucosal level of leptin and the reduction in the severity of mucosal damage was attained following pretreatment with ET(A) receptor antagonist BQ610, but not by ET(B) receptor antagonist BQ788.

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Structural equation modeling using LISREL 8.51 was used to assess the proposed model. Intractable asthma and hostile identification, imprinting in humans, and autonomic mechanisms. We report a revised mRNA and protein sequence for IkappaBR, which predicts that the protein is larger than originally described. These data therefore dissect the TNF receptor 1 proximal events that regulate Tpl2 and ERK and highlight a role for RIP1, TRAF2, and Syk in this pathway. However, there was no apparent difference in the therapeutic effects between a nonselective ET(A)/ET(B) receptor antagonist and selective ET(A) receptor antagonist. Subfascial endoscopic supplementary surgery of perforating veins. Many methods for the determination of aflatoxins have been developed in recent thirty years. The mechanisms behind the formation of a characteristic tissue reaction at the surface of the dorsal root ganglion (DRG) exposed to nucleus pulposus was studied with special reference to apoptosis using electron microscopy and immunohistochemistry in rats. These processing deficits are consistent with the parallel behavioral and physiological deficits recorded in children and adults with a history of language-learning impairment and autism. Noise suppression in reconstruction of low-Z target megavoltage cone-beam CT images.

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Significant differences in enzyme activity have been found between dilated cardiomyopathy and alcoholic heart muscle disease when the groups are defined by detailed drinking histories. A group of 97 residents was followed up for 11 years in order to characterize the long-term persistence of hepatitis B antibodies after vaccination. We present the first case report of onychomycosis in the United States caused by Trichosporon beigelii in a normal, healthy man. French pediatric wards working with 166 microbiology laboratories enrolled all children (0-18 years old) with bacterial meningitis. The deep surface of the anterior aspect of the superficial masseter was biopsied in nine patients at the time of corrective surgery. Overexpression of the O1 tail domain (the C-terminal 644 amino acids) significantly inhibited ER streaming in tobacco (Nicotiana benthamiana) cells. Heat shock-induced augmentation of vascular contractility is independent of rho-kinase. The microsensor exhibited a linear response to both O(2) and N(2)O, and the response to N(2)O was independent of the O(2) concentration and vice versa.

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Slice-based supine-to-standing posture deformation for Chinese anatomical models and the dosimetricresults with wide band frequency electromagnetic field exposure: simulation. Factors responsible for enhancing the system pressures selective for the morphological variants were identified. This review summarizes the clinical dilemma of intestinal ischemia and the latest experimental results using the microdialysis technique to detect critical perfusion in the small intestine. Concomitant administration of Hu-IFN-alpha A and monoclonal antibody may thus be effective in overcoming the antigenic heterogeneity of carcinoma cell populations and in enhancing the efficacy of monoclonal antibodies in the detection and treatment of carcinoma lesions. TAPI polymorphisms in several human ethnic groups: characteristics, evolution, and genotyping strategies. This suggests that autologous and allogeneic MSLR in man depends upon in vitro conditions similar to that studied in animals, and that MSLR may provide an useful tool for the study and the understanding of lympho-epidermal interactions in man. Inflammatory pain was induced by injection of formalin in non-diabetic and diabetic (2 weeks) rats. DNA-Cu(II) poly(amine) complex membrane as novel catalytic layer for highly sensitive amperometric determination of hydrogen peroxide. These observations led us to believe that the calcite might remain as a form of precipitation, not as a bonding material within the matrices.

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Heart rate and hematocrit also decreased in the recent series of 18 animals in which left ventricular bypass pumps were implanted. Using a maize cell suspension culture system and pathogen elicitors, responses to pathogen attack that are localised to the extracellular matrix were examined by a proteomic approach. The field of early intervention in psychosis is young, with encouraging preliminary results, especially for improving outcome in established FEP. Assuming no retardation and no degradation the contaminated plume would have travelled a distance of 1,096 m (best case) to 11,496 m (worst case) in 30 years. typhimurium was suppressed in non-sterilized compost with a maximum population density of less than 10(3) g(-1). Value of digital angiography in the follow-up of vascular reconstructive surgery. Activity in heptane also varied but to a lesser extent than that in water. Recent advances in the treatment of hepatocellular carcinoma (HCC) have prolonged patient survival. On various cardiovascular effects of 4-(3-isoamyloxy, 2-(3,4,5 trimethoxy) benzoyloxy) propyl tetrahydro 1,4 oxazine in the dog. Strong coupling between single photons in semiconductor microcavities.

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Hyper-recombination was found to be dependent on RecA in the dnaE, dnaN and dnaX mutants, whereas the dnaG and dnaD mutants stimulated recombination independently of RecA. The energy contents did not present significant differences in any of the studied periods. It is only in the pharate adult that changes associated with development of the tympana first appear. The same cutaneous reactions occurred after application of heparin calcium. Analogous bioconversion products from alpha-methylionone and alpha-isomethylionone were also identified. In order to reduce any complications and practice safety in radiological units, it is imperative to carry out pre-sedation assessments of children, obtain parental/guardian consent, monitor them closely before, during and after the procedure and have adequate equipment, a safe environment and a well-trained personnel. Distal biceps brachii tendinosis is a relatively uncommon clinical diagnosis seen by physical therapists. In all cases the parathyroid glands were identified, and in two cases of familial MTC, how often can you take pyridium 200 mg in which they were grossly enlarged, the parathyroid glands were removed. Our results point to a potentially important role of Color Doppler myocardial imaging in diagnosing hypertensive heart disease as well as in follow-up of treatment. Exposure to the laser beam during the sorting process caused significant physiological damage.

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A splinting method for replantation of teeth in a noncontiguous arch. Chlor-Floc (CF) emergency water purification tablets were tested for bactericidal, virucidal, and cysticidal efficacy in water at temperatures ranging from 5 to 25 degrees C. In contrast, p53-null HCT116 have higher levels of Hif-1alpha during normoxia and are extremely sensitive to TRAIL, but are protected from TRAIL-induced apoptosis during hypoxia. Results confirm earlier claims that there is an isolatable object-level component to OSM and indicate that a target can be protected from OSM if, prior to offsetting, it can be represented as a distinct object from the mask. Body mass index (BMI) is the dominating weight-for-height index, but its validity as a body fat (BF) index has not been properly examined. This pilot study suggests that 25-OHD levels measured early during critical illness are not important determinants of delirium risk.

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Enzymatic assays: optimization of systems by using pyruvate kinase and lactate dehydrogenase as auxiliary enzymes. The protein level of CrtI was increased to explore its potential for enhancing the flux of metabolites through the pathway. The function of the NF-E2 transcription factor, a p45/small Maf heterodimer, was analyzed in the erythroleukemia cell lines MEL and CB3. In newborn rat pups virtually all sciatic nerve axons are unmyelinated and myelination is an essentially postnatal event. A variety of autoimmune and infectious diseases can result in this condition, which is labeled as idiopathic in the absence of any definite inciting factor.

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Evaluation of symptom presentation and antipsychotic response based on benicar tab 20mg ethnicity in children and adolescents with schizophrenia is limited. NADPH oxidase, the primary source of reactive oxygen species in the cardiovascular system, is a strong candidate for the development of therapeutic agents to ameliorate hypertension and end-organ damage. REporting recommendations for tumor MARKer prognostic studies (REMARK). While the young leaves of plants supplied with nil Cu showed chlorosis and necrotic scorching of laminae, the older and middle leaves of plants supplied with nil or 0.1 microM Cu showed purplish-brown pigmented interveinal areas that later turned necrotic along the apices and margins of leaves. Cardiovascular differences between phenylpropanolamine and its related norephedrine isomers in the rat. Regulation of rodent-borne viruses in the natural host: implications for human disease. Active immunotherapy has been successful in preventing many infectious diseases, and is being explored for its anti-tumor use. Accuracy of the present technique was equivalent to or greater than that of previous methods. Stability of tea polyphenol (-)-epigallocatechin-3-gallate and formation of dimers and epimers under common experimental conditions.

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