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Fosamax (Alendronate)
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Fosamax

Fosamax is used to treat osteoporosis caused by menopause, steroid use, or gonadal failure. Fosamax is for use when you have a high risk of bone fracture due to osteoporosis. Fosamax is also used to treat Paget's disease of bone.

Other names for this medication:
Alant, Alendix, Alendronate, Alenost, Bifosa, Denfos, Osteofos, Ostogee, Poronil, Ralenost, Restofos, Zophost

Similar Products:
Myambutol, Bystolic, Omnicef, Eulexin, Cardura, Calan, Zyloprim, Cordarone, Valtrex, Lopressor

Also known as: Alendronate

Description

{name} Plus D contains a combination of alendronate and cholecalciferol. Alendronate is a bisphosphonate medicine that alters bone formation and breakdown in the body. This can slow bone loss and may help prevent bone fractures.

Cholecalciferol is a form of vitamin D, and is important for the absorption of calcium from the stomach and for the functioning of calcium in the body.

{name} Plus D is used to treat and prevent osteoporosis.

Dosage

Take Fosamax exactly as prescribed by your doctor. Fosamax is taken either once daily or once per week. Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.

Take Fosamax first thing in the morning, at least 30 minutes before you eat or drink anything or take any other medicine. If you take this medicine only once per week, take it on the same day each week and always first thing in the morning.

Take with a full glass (6 to 8 ounces) of plain water. Do not use coffee, tea, soda, juice, or mineral water. Do not eat or drink anything other than plain water.

Do not crush, chew, or suck on an Fosamax tablet. Swallow the tablet whole.

For at least 30 minutes after taking Fosamax:

Do not lie down or recline. Do not take any other medicine including vitamins, calcium, or antacids.

Pay special attention to your dental hygiene while taking Fosamax. Brush and floss your teeth regularly. If you need to have any dental work (especially surgery), tell the dentist ahead of time that you are using alendronate.

Fosamax is only part of a complete program of treatment that may also include diet changes, exercise, bone mineral density testing, and taking calcium and vitamin supplements. Follow your doctor's instructions very closely.

Store at room temperature away from moisture and heat.

Your doctor will determine how long to treat you with this medicine. Fosamax is often given for only 3 to 5 years.

Detailed Fosamax dosage information

Overdose

Drink a full glass of milk and seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Do not make yourself vomit and do not lie down.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Fosamax are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

You should not take Fosamax if you are allergic to alendronate, or if you have:

low levels of calcium in your blood (hypocalcemia); or problems with the muscles in your esophagus (the tube that connects your mouth and stomach).

Do not take Fosamax if you cannot sit upright or stand for at least 30 minutes. Fosamax can cause serious problems in the stomach or esophagus. You must stay upright for at least 30 minutes after taking this medicine.

To make sure this medicine is safe for you, tell your doctor if you have ever had:

trouble swallowing; problems with your stomach or digestion; low levels of calcium in your blood; a dental problem (you may need a dental exam before you begin taking Fosamax); kidney disease; or any condition that makes it hard for your body to absorb nutrients from food (malabsorption).

In rare cases, this medicine may cause bone loss (osteonecrosis) in the jaw. Symptoms include jaw pain or numbness, red or swollen gums, loose teeth, or slow healing after dental work. The longer you use Fosamax, the more likely you are to develop this condition.

Osteonecrosis of the jaw may be more likely if you have cancer or received chemotherapy, radiation, or steroids. Other risk factors include blood clotting disorders, anemia (low red blood cells), and a pre-existing dental problem.

Fosamax has also been reported to cause fractures, or broken bones, in the large bones of the leg. Tell your doctor if you have any leg or groin pain while using Fosamax.

Talk with your doctor about the risks and benefits of using this medication.

It is not known whether Fosamax will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant. Stop using the medicine and tell your doctor right away if you become pregnant.

It is not known whether alendronate passes into breast milk or if it could harm a nursing baby. Ask your doctor about any risk.

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Factorial structure and prognostic significance of premorbid adjustment in schizophrenia. Importance of the diagnosis in the treatment plan in dentofacial orthopedics. Microstructural imaging features of CLs differ from those of WM lesions and are likely to reflect neuronal damage and microglial activation. Analysis of volume displacement and length changes of the diaphragm during breathing. We demonstrated three factors influencing patient survival including treatment of liver metastasis, pre-treatment CEA level, and salvage treatment. This was then followed by an experiment with addition of paclitaxel once weekly for 4 weeks to observe effects of combination drug treatment on diarrhea. Our study suggests that there may be a genetic predilection towards developing focal segmental glomerulosclerosis. Genetic analysis of disheveled 2 and disheveled 3 in human neural tube defects.

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Approval on the basis of regulations designed to safeguard quality of dry powder inhalers does not mean that devices are interchangeable. To establish an oxidative stress model induced by cumene hydroperoxide (cHP) in testis and epididymis of rats in vivo, and to understand the peroxidative damage of oxidative stress in testis, epididymal sperm and its propensity to induce nuclear DNA damage during spermatogenesis and sperm maturation in vivo. Schistosoma japonicum egg excretion and kinship relationship data from 13 endemic villages in the mountainous transmission area near Xichang, in Sichuan province, China, were analyzed via a variance components methodology to assess the relative contribution of kinship, shared household, and shared village to the risk of infection. Glycosylation, the most prevalent post-translational modification of proteins, affects a number of physical properties including the interactions with the surrounding aqueous solvent. Phosphorylation of myosin light chain modulates the in vitro movement of fibrils composed of actin and myosin filaments from skeletal muscle zetia patient reviews . Balance of serum and urinary magnesium in various metabolic and bone diseases. This paper investigates the characteristics of voltage transient response, such as the maximum voltage, direct current (DC) time constant, alternating current (AC) time constant and oscillation frequency, and their applications for a Rosen-type piezoelectric transformer (PT). However, when considering the ratios of the lag phase duration times for post-treated to pre-treated cells, a significant difference was not found, where estimated ratios could exceed 4. The ability of the mammary gland to take up and organically bind radioiodide was studied in non-pregnant, pregnant, and lactating rats.

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Partial characterization of R-plasmids from Pasteurella multocida isolated from turkeys. Factors influencing the agglomeration rate and effect forces are studied, including agglomerator concentration, agglomerator flux and agglomerator density, atomized-particles diameters and inhaled-particles diameter and so on. Combined and sequential treatment using FCE 21336, a new prolactin-lowering drug, and medroxyprogesterone acetate (MPA) in DMBA-induced tumors in rats. Circadian variability is negligible in primary visual cortices as measured by fNIRS. It has been confirmed that examination for these in addition to formiminoglutamic acid is necessary for a full assessment of this test. Five out of six VEGF patients experienced a reduction in anginal complaints. The cell division cycle 25 phosphatases (CDC25s) are key regulators of the physiological cell cycle progression. However, since centrosomes are involved in multiple processes in vivo, including polarized cell divisions, which are an essential developmental mechanism for producing differentiated cell types, it remains to be shown whether or not a complete organism can develop without centrosomes. However, there appeared to be a relationship between abnormal development and the actual or estimated pKa values of the 10 retinoids tested.

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