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Imitrex (Sumatriptan)

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Imitrex is an inexpensive drug used to treat migraines. It is more popular than comparable drugs. It is available in generic and brand versions. Generic Imitrex is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.

Other names for this medication:
Migratan, Sumatriptan, Suminat, Sumitrex

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Also known as: Sumatriptan


Imitrex is a perfect remedy in struggle against the symptoms of migraine headaches. Imitrex acts by narrowing blood vessels in the head and stopping pain signals from being sent to the brain. It is selective serotonin receptor agonists. Imitrex is also known as Sumatriptan, Imigran. Generic name of Imitrex is Sumatriptan. Brand names of Imitrex are Imitrex, Imitrex nasal.


Do not use this medicine for a headache that is different from your usual migraines. Talk to your doctor about what to do for regular headaches.

To relieve your migraine as soon as possible, use this medicine as soon as the headache pain begins. Even if you get warning signals of a coming migraine (an aura), you should wait until the headache pain starts before using sumatriptan.

Ask your doctor ahead of time about any other medicine you might take if sumatriptan does not work. After you use the other medicine, check with your doctor as soon as possible. Headaches that are not relieved by sumatriptan are sometimes caused by conditions that need other treatment.

If you feel much better after a dose of sumatriptan, but your headache comes back or gets worse after a while, wait at least 2 hours before taking another dose. However, use this medicine only as directed by your doctor. Do not use more of it, and do not use it more often, than directed. Using too much sumatriptan may increase the chance of side effects. Do not take more than 200 mg in 24 hours.

Swallow the tablet whole with water or other liquids. Do not crush, break, or chew it.

You may take the tablet with or without food.

This medicine comes with a patient information leaflet. Read and follow the instructions carefully. Ask your doctor if you have any questions.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For oral dosage form (tablets): For migraine headaches: Adults—25, 50, or 100 milligrams (mg) as a single dose. If you get some relief, or if the migraine comes back after being relieved, another dose may be taken 2 hours after the last dose. Do not take more than 200 mg in any 24-hour period. Children—Use and dose must be determined by your doctor.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include tremors, skin redness in your arms or legs, weakness, loss of coordination, breathing problems, blue-colored lips or fingernails, vision problems, or a seizure (convulsions).


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Throw away used syringes or autoinjectors in a hard, closed container that the needles cannot poke through. Keep this container away from children and pets.

Detailed Imitrex dosage information

Side effects

The most common side effects associated with Imitrex are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

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OBJECTIVE To study the clinicopathologic features, radiologic findings, treatment modalities and prognosis of dysembryoplastic neuroepithelial tumor (DNT). A case of hyperinsulinemia of undetermined origin, successfully treated with long-acting octreotide. Demonstration by arteriography and successful treatment with infusion of vasopressin into the superior mesenteric artery. The structure of lactiflorasyne isolated from Artemisia lactiflora wall. Only 11 qualitative changes in protein expression and 26 quantitative changes greater than two-fold were observed. The influence on the kinetics of T-helper cells was responsible for a significant decrease of helper/suppressor ratios in the intravascular compartment. Anaesthesia for patients undergoing ventricular assist-device implantation. Wound healing in the colon and the effect of fibrinolysis and collagenolysis. fumigatus, differential patterns of enzymes of the gluconeogenesis, glyoxylate cycle and ethanol degradation pathway during growth on glucose and ethanol were observed.

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Demonstration of the plasminogen activator in Ehrlich ascites tumor cells. At necropsy, there was no evidence of a pulmonary arteritis or vascular immune-complex deposition to account for the recurrent thromboembolic lesions in the small pulmonary arteries and arterioles. Myocardial injury recruits endothelial progenitor cells (EPCs) to the site of damage and stimulates their differentiation, contributing to myocardial tissue repair. We next examined ET patients that had undergone unilateral thalamotomy in the cerebellar thalamus and found that adaptation with the contralateral arm was impaired compared with the ipsilateral arm. Serum relaxin concentrations were measured every 30 min during a 24-h period in nonpregnant and pregnant women. The MTGXO consists of about 15 large perikarya, forming a distinct subgroup of neurosecretory cells in the medulla terminalis and giving rise to a prominent fibre bundle. To determine whether measures of transitional zone volume (TZV) are more strongly associated than total prostate volume with longitudinal urologic outcomes. Oral anticoagulation in atrial fibrillation: balancing the risk of stroke with the risk of bleed. Adhesion between the fluorescent HepG2 cells and human umbilical vein endothelial cells (HUVEC) was examined by solid phase adhesion assay in vitro. In four cases 4.0-9.0 months were needed to establish the diagnosis.

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At the same time we found a greater activity of the musculi glutaei medii than with the brace taken off. Mutations and polymorphism of chaperones and the regulators of their synthesis, heat shock factor-1, chaperone diseases, sick chaperones and chaperone overload might all affect (mostly impairing) immune responses. A similar role for Rab7 and RILP has been demonstrated also for phagosomes. Here the effect of cell hydration on MG-132-induced MKP-1 expression was investigated in H4IIE rat hepatoma cells. A surgical operation of liver resection was successfully performed at 16 GW. Serum nutritional markers can be used to predict the probability of PEI in CP and provide guidance in decisions on enzyme replacement therapy. The different spectral features developed for the classification are tested on a real-life material originating from human lymphoblast samples and on a standard mixture of 9 proteins, both labelled with the ICAT-reagent. Antero-postero differences in cortical thickness and cortical porosity of T12 to L5 vertebral bodies. Logistic regression analysis was used to examine differences in symptoms of AMI according to the presence of kidney disease while controlling for several potentially confounding demographic and clinical factors.

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Exogenous addition of arachidonic acid, the cleavage product of PLA2G4A-catalyzed lipolysis, but not other related poly-unsaturated fatty acids restored infectivity. We describe the successful treatment of a patient with iatrogenic acute aortic dissection including cerebral malperfusion as a complication of coronary artery surgery. Interfacial electric energy density values were calculated using the electric field intensity and the dielectric permittivity obtained by the fitting of the experimental points. Ringing the alarm bells: signalling and apoptosis in influenza virus infected cells. For subperiosteal abscess, in particular, there are no generally accepted therapy recommendations. spiralis-infected mice and diminished the influx of eosinophilic granulocytes, goblet cell hyperplasia, and villous atrophy, it was concluded that during a T. As judged by monoclonal antibodies, two of the PHA-derived T-cell lines carried the helper-inducer (H-I) phenotype and two the suppressor-cytotoxic (S-C) phenotype. Lamivudine prophylaxis reduces the incidence and severity of hepatitis in hepatitis B virus carriers who receive chemotherapy for lymphoma.

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Both single flexible chains and flexible loops can adopt different configurations (straight, hairpin, S-shaped, etc.) when subjected to magnetic fields, the configurations depending on the directions of these fields. Three-year follow-up after withdrawal of iron therapy in uremic patients on regular dialytic treatment. To investigate the role of the endogenous cystathionine gamma-synthase (CSE)/hydrogen sulfide (H2S) pathway in vascular calcification in vivo. Effects of selective dopamine D2-receptor agonists on the release of cholecystokinin-like immunoreactivity from rat neostriatum. A two-level floc structural model comprised of (i) a primary floc (of fractal dimension D(S)) consisting of primary particles and (ii) a secondary floc (of fractal dimension D(F)) consisting of the microflocs is proposed to interpret the experimental findings. Although all three Lys residues of CtBP2 (Lys-6, Lys-8, and Lys-10) appear to be acetylated, acetylation of Lys-10 is critical for nuclear localization. Surgical correction of the skeleton in the area of the orbit and maxilla. We conclude that, at present, only one rating scale measuring suicidality specifically designed for patients with schizophrenia (the InterSePT-scale) is based on both sound methodology and has clinical relevance.

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Although minor elevations in osteoid surface and osteoid volume are found among distal RTA patients, overt osteomalacia is not the predominant bone lesion. Clonidine hydrochloride, 0.05 mg, was given orally twice daily for two weeks. Synthesis, crystal structure, and catalytic properties of MgCo6Ge6. A gamma-variate curve was fit to the time-density data obtained from the inlet and outlet, as well as from the tissue-equivalent part of the phantom. Differential ethanol intake in high and low responders to novelty. In the present study, the behavioral effects of a 5,7-dihydroxytryptamine (5,7-DHT) lesion in the dorsal raphe were evaluated in animal models of anxiety (open field test), depression (forced swimming test), behavioral inhibition (discrete fixed interval test) and cognition (object recognition task). Parameters affecting the efficiency of Agrobacterium tumefaciens-mediated transformation of Colletotrichum graminicola. Isolation of linkage-region glycopeptides from corneal peptidokeratan sulfate was attempted under mild conditions. Although clinical signs developed within six weeks of vaccination in all 12 dogs for which information was available, no association was found between DQA1 alleles and HOD in this population of Weimaraner dogs.

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We find evidence of substantial underreporting, which is indeed systematically higher for individuals in the labor market. COX-2 expression is most evident at sites of inflammation, while COX-1 accounts for most of the PG synthesis in the normal gastrointestinal tract. The electroreduction of the disulphide bonds of insulin and other proteins. A brief discussion on using this technique to estimate the rheological properties of wormlike micelles is presented. In vitro antibacterial activity of norfloxacin compared with eight other antimicrobial agents. Wear particles generated following total joint arthroplasty interact with cells at the periprosthetic margin and induce an inflammatory response that contributes to osteolysis, aseptic loosening, and implant failure. Consequently, Ca entry via activated NCX is favored, which together with ROS-induced dysfunction of the sarcoplasmic reticulum can lead to dramatic intracellular Ca accumulation, diminished contractility, and arrhythmias.

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Twelve of the 13 bushcricket species of the Saga genus are bisexuals and diploids, except the parthenogenetic and tetraploid bush cricket, Saga pedo. Quantitative imaging of red blood cell velocity invivo using optical coherence Doppler tomography. Socioeconomic indicators and oral health services in an underprivileged area of Brazil. The transient imbalance of a Wheatstone bridge was used to estimate the changes in both membrane and myoplasmic impedance that occurred as an action potential propagated over a 1 mm length of a frog muscle fiber. This distortion can be mathematically predicted with the magnification varying at each point in the image.

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The purpose of this study was to determine the effects of zinc-supplementation on the TJs of a well-studied in vitro GI model, CACO-2 cells. An intravascular loopless monopole antenna for vessel wall MR imaging at 3.0 T. On the osteogenesis of the bone system and the growth of the skull and extremities in the chicken (Gallus domesticus). Our findings indicate that the presence of isolated BBB denotes a high-risk patient subgroup that has a compromised long-term outcome comparable to patients with conventional cardiovascular risk factors. Twenty-seven issues were extracted that are not covered by the current version of the European Organization for Research and Treatment of Cancer (EORTC) questionnaires. The mean duration of treatment varied from 5.5 to 8.2 days for tazobactam/piperacillin and 5 to 9.4 days for imipenem/cilastatin. We next examined the effect of astrapterocarpan on PDGF-BB signal transduction. A knowledge of the anatomy, pathology, and physiology of the area is essential. The regions of the adenovirus type 12 genome which encode l- and r-strand-specific cytoplasmic RNA were mapped by the following procedure.

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Search terms included evidence-based medicine, evidence-based practice, resources, and abstraction. Our observations suggest that atmospheric transport of PCBs contributes to levels in the Yupik people, but that the abandoned military site at the NEC may also contribute to the human body burden in those individuals who have either spent substantial time or consumed food from zopiclone tablets there. A comparison between a combination of ipratropium bromide plus fenoterol in a single metered dose inhaler (Duovent) and salbutamol in asthma. Furthermore, many NET treatments do not induce cytotoxic effects despite demonstrated clinical benefit. Dysbindin (DTNBP1, 6p22.3) is associated with childhood-onset psychosis and endophenotypes measured by the Premorbid Adjustment Scale (PAS).

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In a longitudinal study the postnatal physical growth of 188 small for gestational age and 225 appropriate for gestational age children was compared. Traumatic brain injury is a major cause of death and disability. Additional results revealed a facilitatory effect of Instrumentality in both languages. Effects of environment on enhancing functional plasticity following cerebral ischemia. By comparison, obestatin lacked specific binding and endocytosis, and the small amount internalized showed rapid intracellular degradation before the radioactivity was released by exocytosis. Thermodynamics of the isothermal interaction of human immunoglobulin G with guanidinium chloride. The IGF-I/IGFBP-3 system in gingival crevicular fluid and dependence on application of fixed force. OKCs show proliferation and genuine maturation behavior reminiscent of benign neoplasms with local destructive capacity.

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The results indicate that antibodies directed to certain epitopes of P44 proteins have a critical role in inhibiting A. BV was not associated with spontaneous preterm birth, but was associated with both LBW and SGA in nulliparous women. In some fast glycogenolytic fibers (FG) central calcifications, probably representing mitochondria, were observed. The commonest aetiology was biliary tract disease (30 per cent of males and 53 per cent of females). Most commonly used probiotics come from the genera Bifidobacterium and Lactobacillus but other species are in trial. During follow-up at 34 weeks of gestation, concomitant emergency cesarean section and transsphenoidal surgery were performed because of advancing vision loss. Recent results of pulmonary arterial angioplasty: the differences between proximal and distal lesions. It has been suggested that closure of the abdominal fascia may be unnecessary when such nonbladed trocars are used.

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The interviews were recorded, transcribed and subjected to content analysis, in which the text was analysed in five steps, inspired by Graneheim and Lundman. Insulin administration resulted in Cbl phosphorylation in cardiac, skeletal muscle, and adipose tissue. The as-prepared CdSe nanocrystals were well dispersed and uniform in shape and the diameter of the particles was confined within 8 nm. Nucleic acid amplification methods have promoted this development. 17 141 peripheral blood samples of 0-6 years old children from 15 cities in China were tested. Effect of gamma ray low doses on the system how much does a ventolin inhaler cost without insurance of the nonspecific defense of the organism. This situation leads to delays in treatment or to transfer of patients to other centres for stent insertion.

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Net sodium and water movements in the newborn rabbit collecting tubule: lack of modifications by indomethacin. Because of overlapping toxicities, there have been challenges in combining some of these agents in full dose with combination paclitaxel plus platinum. A spectral correlation function for efficient sequential NMR assignments of uniformly (15)N-labeled proteins. In PC-ANN models, the spectral data were initially analyzed by principal component analysis. The second method is an iterative resolution procedure named the stepwise key spectrum selection which has also been developed to resolve automatically the spectra and chromatographic profiles of every component in the peak cluster investigated. Since EphA2-Fc receptors can inhibit activation of multiple EphA receptors, the specific role of EphA2 receptor in angiogenesis was further investigated in EphA2-deficient endothelial cells. Renin release in response to Renin system blockade: activation of the Renin system in type 1 diabetes mellitus. Disparities in survival exist among American Indians/Alaska Natives patients with HNSCC. It is concluded that the radial SCV is the most reliable conduction test and is proposed as an early diagnostic test for leprosy. Neuronal responses to transient hypoglycaemia in the dorsal vagal complex of the rat brainstem.

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These results suggest that the drinking of green tea with a high catechin content may help to prevent and/or attenuate the development of a certain type of hepatitis. We encountered several patients with rhabdomyolysis and elevated cTnI, although they did not otherwise have evidence of cardiac injury. Determination of IL-12 protein secretion by enzyme-linked immunosorbent assay of culture supernatants from both macrophage types infected with either Lp-V or Lp-Av showed only minimum production. However, burst fracture can be managed conservatively, provided the neurologic condition improves. Offering a potentially unlimited source of material, directed differentiation of pluripotent cell lines has zithromax 500 mg iv dilution been particularly well combined with high-throughput transcriptomic and epigenetic analyses. In our patients the genotype is correlated with the biochemical phenotype whereas the cognitive phenotype depends on determining factors such as early diagnosis and diet.

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The amounts of carboxymethyl cellulase present in the midguts and hindguts of two species of cockroaches were determined. Modification of the cytosol, for example, by immunodepletion or addition of purified proteins, allows the identification of proteins involved in vesicle formation. In addition, we discuss recent developments with respect to alternative donors, stem cell sources, and supportive care. To determine the occurrence and effect of incidental deep ulnar nerve (DUN) costimulation during palmar stimulation of the recurrent median nerve (RMN). The use of airbag systems in motor vehicle construction has led to a significant reduction in both the frequency and intensity of injuries during traffic accidents. In this study, we compared mechanisms involved in two eryptotic models (oxidative stress and cell calcium overload) so as to distinguish whether they share signaling pathways and could be prevented by erythropoietin (Epo). Understanding bullying among younger prisoners: recent research and introducing the Multifactor Model of Bullying in Secure Settings.

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Medical management of arrest disorders of labor: a current overview. To report further observations on an established cohort of patients with gastro-oesophageal reflux disease, after 7 years of follow-up. There is some suggestion that its initially elastic properties, present during the early days after implantation, make it more compliant during this healing period and more adaptable to the actual flow conditions present at the time of its insertion. Complete or major cytogenetic response (CgR) was obtained in 4 patients, minor in 5 minimal in 7, and no response in 5 patients. The milled RNC restorations can be individualized intra-orally or extra-orally, either before or after insertion. Administration of monoclonal antibodies to the product of the I-Jk subregion of the major histocompatibility complex or low doses of cyclophosphamide in vivo inhibited the development or activity prilosec dosage chart of these cells.

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This is basically explained by the involuntary injection of embolizing material into the anastomoses between the external and internal carotid arteries within the orbit. Balance was tested with the Timed Up and Go test (TUG), the Functional Reach test (FR) and the Falls Efficacy Scale (FES) (Swedish Version). When the concentration of Chl-a was high, the degradation effects of mixed strain excelled that of any single strains. Minireview: progress and challenges in proteomics data management, sharing, and integration. Plasma arginine-vasopressin (AVP) levels were measured by radioimmunoassay in 26 untreated myxoedematous patients and 27 healthy subjects.

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Despite only a moderate response to treatment, patient satisfaction with the service was high, emphasising the importance of good communication when managing children with chronic, debilitating conditions. Blood flow to the wound increased significantly by day 4 and returned toward baseline by day 14. Clinical examination revealed bilateral branchial fistulae and preauricular sinuses, on a background of a positive family history of branchial fistulae. The shortest splice variant, osteopontin-c, does not aggregate in the presence of calcium and enhances clone formation in soft agar. The instrument consists of a pinching device attached to a flexible arm and a fixation clamp. Cross-sectional study via telephone survey of parent drivers and children (aged 5-15 years), using an exposure-based crash surveillance system. Because anti-CD48 interferes with these processes, anti-human CD48 antibody treatment may represent a novel therapy for inflammatory bowel disease patients. The details about the research productivity of the biomedical journals published from India is lacking.

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