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Lasix (Furosemide)

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Lasix is a loop diuretic (water pill) that makes you urinate more. It works in the kidneys to get rid of extra water and electrolytes (like sodium and potassium), which helps with swelling and lowers blood pressure. Lasix can be taken once or twice a day for swelling. Adults typically start with 20 mg to 80 mg per dose. Some adults with really bad swelling problems may take up to 600 mg in a day.

Other names for this medication:
Aldalix, Anfuramide, Ansemid, Betasemid, Foliront, Frusemide, Frusenex, Furantral, Furesis, Furetic, Furide, Furocot, Furosemide, Furovet, Furoxem, Furozenol, Fursemid, Furtenk, Fusix, Inclens, Intermed, Jufurix, Lasilacton, Lasilactone, Lasiletten, Lasilix, Salix, Vesix

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Also known as: Furosemide


Lasix is a potent diuretic. It inhibits sodium and chloride absorption in the ascending limb of Henle's loop and in both the proximal and distal tubules. The high degree of efficacy is due to this unique site of action. The action on the distal tubule is independent of any inhibitory effect on carbonic anhydrase or aldosterone.

Frusemide may promote diuresis in cases which have previously proved resistant to other diuretics.

Frusemide has no significant pharmacological effects other than on renal function.


Adults. The usual initial daily dose is 20 to 80 mg given as a single dose. If the diuretic response to a single dose of 20 to 80 mg is not satisfactory, increase this dose by increments of 20 to 40 mg, not sooner than 6 to 8 hours after the previous dose, until the desired diuretic effect is obtained. This individually determined dose should be given once or twice (e.g. at 8 am and 2 pm) daily. The dose of Lasix may be carefully titrated up to 400 mg/day (except in advanced renal failure) in those patients with severe clinical oedematous states. The mobilisation of oedema may be most efficiently and safely accomplished by giving Lasix on 2 to 4 consecutive days each week.

When doses exceeding 80 mg/day are given for prolonged periods, careful clinical laboratory observations are particularly advisable.


In case of a Lasix overdose visit your doctor or health care provider immediately. Symptoms of a Lasix overdose include fainting, tinnitus, confusion, weakness, lightheadedness, lack of appetite.


Keep this medicine in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away unused furosemide solution after 90 days. Throw away any medicine that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medicine.

Side effects

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Excessive diuresis may result in dehydration and reduction in blood volume with circulatory collapse and with the possibility of vascular thrombosis and embolism, particularly in elderly patients.

Excessive loss of potassium in patients receiving cardiac glycosides may precipitate digitalis toxicity.

In patients with hepatic cirrhosis and ascites, initiation of therapy with Lasix is best carried out in hospital. Sudden alterations of fluid and electrolyte balance in patients with cirrhosis may precipitate hepatic coma, therefore, strict observation is necessary during the period of diuresis.

Cases of reversible or irreversible tinnitus or hearing impairment have been reported. Usually, reports indicate that Lasix ototoxicity is associated with rapid injection or infusion, severe renal impairment, hypoproteinaemia, doses exceeding several times the usual recommended dose, or concomitant therapy with aminoglycoside antibiotics, ethacrynic acid, or other ototoxic drugs. In patients with hypoproteinaemia, e.g. associated with nephrotic syndrome, the effect of Lasix may be weakened and its ototoxicity potentiated. Cautious dose titration is required. If the physician elects to use high dose parenteral therapy, controlled intravenous infusion is advisable (for adults with normal renal function, an infusion rate not exceeding 4 mg Lasix per minute must be used; for adults with impaired renal function, an infusion rate of no greater than 2.5 mg per minute must be used).

Caution should be exercised when administering curare or its derivatives to patients undergoing frusemide therapy. It is also advisable to discontinue frusemide for one week prior to any elective surgery.

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Activity of the TNF-related apoptosis-inducing ligand gene expressed from the hTERT promoter on colon cancer cell line HT-29. Transformation of Escherichia coli K-12 with a high-copy plasmid encoding the green fluorescent protein reduces growth: implications for predictive microbiology. Budesonide (Entocort) is effective for the treatment of collagenous colitis. The normally quiescent cells were made to enter cell cycle by treatment with either irradiation or the phase specific drug cytosine arabinoside (Ara-C). A method for the quantitative recovery of this mixed polymer, called poly-beta-hydroxyalkanoate (PHA), with analysis by capillary gas-liquid chromatography, showed the presence of at least 11 short-chain beta-hydroxy acids in polymers extracted from marine sediments. Passive cutaneous anaphylaxis in the guinea pig toward the Nichols spirochete by means of the blood and parotid secretion of syphilitic patients. Hemorrheologic abnormalities in defined primary dyslipoproteinemias with both high and low atherosclerotic risks.

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The predictive value of serum uric acid, roll-over test, and body mass index in pre-eclampsia. This technique is very helpful in characterizing the typical structural features of the epidermal layers, the arrangement of the collagen fibre bundles and the elastic fibre network in the dermis, the external and internal construction of hair follicles and hair shafts, and the functional development of skin glands. The tested confectionary did not have any similar stimulating effect but seemed to counteract the expected decrease of IgE. Tests of the E-Z Reader model: exploring the interface between cognition and eye-movement control. Correlation between HER2 determined by fluorescence in situ hybridization and reverse transcription-polymerase chain reaction of the oncotype DX test. Starting combined estrogen and progesterone hormone replacement therapy in either early or late postmenopause produced a persistent, steady-state 9-fold increase in epithelial cell proliferation, which could be a contributing factor to increased breast cancer risk. Nucleotide sequence of a region of the cytochrome c oxidase subunit I gene of mitochondrial DNA from an adult worm was identical with that from the plerocercoid. The results are interpreted by the gated-pore mechanism where two subunits form a gate with a central binding site which radically change conformation and specificity on transition from one to the other side of the membrane. Allogeneic stem cell transplantation is a potentially curative therapy for patients with multiple myeloma.

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205 patients with a prior bariatric operation were excluded from the review, leaving 1,383 patients who had a primary SRVGBP. Several carbon metabolism enzymes were measured in cultured cells and bacteroids of Rhizobium meliloti 102F51 and in alfalfa root nodule cytosol. This report provides specific cautions for interpreting negative QFT-G results in persons from selected populations. Evaluation of two GnRH-I based vaccine formulations on the testes function of entire Suffolk cross ram lambs. The aim of the present study was to evaluate the efficacy of terazosine in patients with premature ejaculation and lower urinary tract symptoms (LUTS), after excluding other sexual disorders and chronic prostatitis. To compare polymerase chain reaction (PCR) results to presumptive clinical diagnosis in patients with vitritis. Practice profiles are reflective pieces written by nurses in practice and based on continuing professional development articles. Calcium sulfate appears to be a useful biocompatible bone graft substitute that yields results similar to autograft bone in sheep metaphyseal defects. Genetic control of delayed-type hypersensitivity to highest dosage of xanax BCG in mice and the suppressor T cells. Our findings demonstrate that selective inhibition of PDE1 augments the therapeutic efficacy of inhaled NO in an ovine model of acute chemically induced pulmonary hypertension.

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The long road to patient safety flagyl 500 mg tabletas para que sirve : a status report on patient safety systems. Experimental study and possible use in primary cleft lip repairs. Cerebral pseudoatrophy and computed tomography: two illustrative case reports. Computational modelling has suggested that at least two counteracting forces are required for establishing topographic maps. crassa mycelial cells for light-dependent accumulation of carotenoid pigments has been studied. Parasite infection decreased 57 (inclusive of IL-12 and TNF-alpha) and increased expression of 7 of 77 LPS-activated cytokine and cytokine-related genes. In particular, anomalies in lipid metabolism, including low essential fatty acid status and decreased serum cholesterol, have been identified in all three disorders. Legal requirements for clinical trials and licensing of nucleic vaccines are in place in Germany and other European member states which allow further testing and development of proprietary medicinal products based on nucleic acids and intended for prophylactic vaccination.

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Gene expression and metabolite profiling of Populus euphratica growing in the Negev desert. Remnant particles were isolated from the d less than 1.019 g/ml fraction by heparin-Sepharose chromatography (heparin-bound fraction) after removing the large chylomicrons by flotation at 7,8 X 10(5) g-min. When steps were taken to clear endogenous transferrin from the membranes, the labeling of this species was enhanced. Only modest conformational changes within this structure imodium 2 mg tabletti are needed to form the symmetric, planar DNA junction, which may be characteristic of shorter-lived intermediates along the recombination pathway. The mitochondrial effects of small organic ligands of BCL-2: sensitization of BCL-2-overexpressing cells to apoptosis by a pyrimidine-2,4,6-trione derivative. Activation products of the haemostatic system in coronary, cerebrovascular and peripheral arterial disease. Because the epididymis is functionally T-dependent, our data suggest that the removal of zinc from the outer dense fibers during epididymal sperm maturation is affected in aging men, which in turn will result in decreased sperm motility. Urgent surgical airway intervention: a 3 year county hospital experience. Fibroblasts also produce proteoglycans which are important in fibrillogenesis.

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Our results suggest that local tumor therapy could prolong the survival time of patients with malignant biliary obstruction, and may improve stent patency. Mast cells, which interact with Escherichia coli, up-regulate genes associated with innate immunity and become less responsive to Fc(epsilon)RI-mediated activation. Platelet inhibition at the time of a percutaneous coronary intervention has consistently been shown to decrease the risk of thrombotic adverse events but not restenosis. The results of this study support the overall good safety profile of MF59 adjuvanted cell culture-derived influenza vaccine as administered in adults during the 2009-2010 H1N1 influenza pandemic. However, the classification and mechanisms of different CRS phenotypes remains problematic.

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To determine cardiovascular risk profiles of patients with Kawasaki disease and to does allegra help with sinus infection relate them to a noninvasive measure of endothelial function. CA3 was the hippocampal area most affected by chronic alcohol intake. A program for producing contour maps of three-parameter flow cytometric data is described. HBsAg levels correlated with CD4 T-cell count and were higher in patients with more advanced HIV CDC stage. Thus, c-Src appears to have pleiotropic effects on cancer cells by modulating the action of multiple growth-promoting receptors. Elevated cerebral lactate levels following cerebral ischemia have been associated with brain cell damage and death.

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A questionnaire administered to a convenience sample of 200 parents/carers who attended the paediatric ED and whose children were categorized as having non-urgent problems that had been present for at least 4 weeks. ERCC1 C19007T polymorphism and the risk and invasiveness of cervical cancer in Korean women. Intestinal ischemic injury following mild hypothermic stress in the neonatal piglet. In adult tissues, the hsp68 gene was expressed constitutively in the kidney. Clinical observation of lactate dehydrogenase isoenzyme and serum and leukocyte LDH values in myelogenous leukemia.

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Herds were monitored for fecal shedding of S enterica Newport after outbreaks of clinical disease. Measured distance distributions for dsDNA can be accounted for by considering fluorophore linkers and fluorophore rotational diffusion, except that we find smaller fluctuations for internally labeled dsDNA than DNA with one of the fluorophores positioned at a terminal site. Some population genetic models combining artificial and natural selection pressures. The outgrowth of spoilage organisms, including molds and yeasts, results cost of enalapril without insurance in significant financial loss to the food industry and wastes natural resources. Impact of HMOs on emergency medical services: another perspective.

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