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Lopressor (Metoprolol)

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Lopressor is an inexpensive drug used to treat high blood pressure and prevent chest pain. It is also used after a heart attack to prevent an additional heart attack from occurring. This drug is more popular than comparable drugs. It is available in brand and generic versions.

Other names for this medication:
Actiblok, Actocard, Asoprol, Betaloc, Betaone, Blumeta, Dutoprol, Intramet, Macsart, Mepol, Metapro, Metin, Metocare, Metofin, Metolar, Metolex, Metomac, Metoprolol, Metozest, Metpure, Metscore, Metzok, Nexovas, Powermet, Sitelol, Supermet, Telidin, Teliprolol, Toprol, Translol, Vasomet, Vinicor, Vivalol

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Also known as: Metoprolol


Lopressor is a perfect remedy. Its target is to struggle against high blood pressure. It also can be used in the treatment of chest pain, heart attacks. Lopressor acts by slowing the heart rate and relaxing the blood vessels. It is beta blocker. Lopressor is also known as Toprol-XL, Metoprolol, Protomet, Lopresor, Lopresar. Generic name of Lopressor is Metoprolol Tartrate. Brand names of Lopressor are Toprol-XL, Lopressor.


This section provides information on the proper use of a number of products that contain metoprolol. It may not be specific to Lopressor. Please read with care.

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. Your dose may need to be changed several times in order to find out what works best for you.

In addition to the use of this medicine, treatment for your high blood pressure may include weight control and changes in the types of food you eat, especially foods high in sodium (salt). Your doctor will tell you which of these are most important for you. You should first check with your doctor before changing your diet.

Many patients who have high blood pressure will not notice any signs of the problem. In fact, many patients feel normal. It is very important that you take your medicine exactly as directed and that you keep your appointments with your doctor even if you feel well.

Remember that this medicine will not cure your high blood pressure, but it does help control it. You must continue to take it as directed if you expect to lower your blood pressure and keep it down. You may have to take high blood pressure medicine for the rest of your life. If high blood pressure is not treated, it can cause serious problems such as heart failure, blood vessel disease, strokes, or kidney disease.

Swallow the extended-release capsule and tablet whole. Do not crush, break, or chew them.

If you cannot swallow the extended-release capsule:

You may open it and sprinkle the contents over a small amount (teaspoonful) of soft food (including applesauce, pudding, or yogurt). Swallow the mixture within 60 minutes. Do not store for later use. You may also use a nasogastric tube to give the medicine. Mix the contents of the opened capsule with water into a syringe. Gently shake the mixture for about 10 seconds, then flush it through the tube. Rinse the tube with water until all of the medicine is washed out.

Take the tablet or extended-release tablet with a meal or just after you eat. You may break the extended-release tablet into two pieces, but swallow the two pieces whole and do not crush or chew them.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For acute heart attack or heart failure: For oral dosage form (extended-release capsules): Adults—At first, 25 milligrams (mg) once a day for 2 weeks. Your doctor may adjust your dose as needed. However, the dose is usually not more than 200 mg per day. Children—Use and dose must be determined by your doctor. For oral dosage form (extended-release tablets): Adults—At first, 25 milligrams (mg) once a day for 2 weeks. In patients with severe heart failure, the starting dose is 12.5 mg once a day. Your doctor may adjust your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage form (tablets): Adults—At first, 50 milligrams (mg) every 6 hours for 2 days. Then, 100 mg 2 times a day. The medicine will be started in the hospital. Children—Use and dose must be determined by your doctor. For chest pain: For oral dosage form (extended-release capsules): Adults—At first, 100 milligrams (mg) once a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 400 mg per day. Children—Use and dose must be determined by your doctor. For oral dosage form (extended-release tablets): Adults—At first, 100 milligrams (mg) once a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 400 mg per day. Children—Use and dose must be determined by your doctor. For oral dosage form (tablets): Adults—At first, 100 milligrams (mg) per day, given in two divided doses. Your doctor may adjust your dose as needed. However, the dose is usually not more than 400 mg per day. Children—Use and dose must be determined by your doctor. For high blood pressure: For oral dosage form (extended-release capsules): Adults—At first, 25 to 100 milligrams (mg) once a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 400 mg per day. Children 6 years of age and older—Dose is based on body weight and must be determined by your doctor. The dose is usually 1 milligram (mg) per kilogram (kg) of body weight once a day. The first dose should not be more than 50 mg once a day. Your doctor may adjust your dose as needed. Children younger than 6 years of age—Use and dose must be determined by your doctor. For oral dosage form (extended-release tablets): Adults—At first, 25 to 100 milligrams (mg) once a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 400 mg per day. Children 6 years of age and older—Dose is based on body weight and must be determined by your doctor. The dose is usually 1 milligram (mg) per kilogram (kg) of body weight per day, given as a single dose. The first dose should not be more than 50 mg per day. Children younger than 6 years of age—Use and dose must be determined by your doctor. For oral dosage form (tablets): Adults—At first, 100 milligrams (mg) per day, given as a single dose or in divided doses. Your doctor may adjust your dose as needed. However, the dose is usually not more than 450 mg per day. Children—Use and dose must be determined by your doctor. .


If you overdose Lopressor and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Lopressor overdosage: fainting, difficulty, breathing or swallowing, swelling of the hands, feet, ankles, or lower legs, lightheadedness.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Lopressor are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

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Detection by contrast echocardiography and the cough provocation test. The latest developments are typically those found in the New Research sections, which is where this summary will focus. This platelet reaction was weaker than that to collagen in case of bleeding in the previous report. In either case, we show that FoxO4 (but not FoxO3) is required as proapoptotic mediator. These endothelial receptors recruit leukocytes from the bloodstream and facilitate their transendothelial migration (TEM) toward the inflamed area. The N gene is a Toll/interleukin-1 receptor (TIR)-nucleotide-binding site (NBS)-leucine-rich repeat (LRR)-type resistance (R) gene that generates two alternative transcripts, N(S) and N(L). Finally, Reusch has extended the importance of short chain PHB to medicine by showing its likely involvement in atherogenic plaques and diabetes. Although mean serum PSA and CSF PSA levels in the patients with cancer of the prostate and lower spine metastasis are higher than those in the others, the mean CSF PSA/serum PSA ratio is lower. TPs in the lower rectus abdominis refer pain horizontally across the low back, and those in the iliopsoas refer pain in a vertical pattern, parallel to the lumbosacral spine. A data collection form was used to record the relevant information.

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Diabetic retinopathy, nephropathy and cardiovascular disease in a patient with GH gene deletion. Deleterious effects due to hemorrhage after myocardial reperfusion. The occurence of side-effects and the return to normal cycles are presented and discussed. Such a comparison may be provided by an exogenous receptor that is activated by compounds that have no effect on endogenous receptors. We did a population-based retrospective cohort study in Ontario, Canada, of 1.03 million women who were free from cardiovascular disease before their first documented delivery.

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Stereoselectivity in metabolic 3-reduction of tibolone in healthy Chinese female volunteers. Analyses of inheritance have shown that a single gene segregating in an autosomal recessive fashion is causative for PAA. In general, fruit from both plants had higher levels of the peptide than the vegetative parts. Inhibition of acid concentrations was dose-dependent and prolonged, including nocturnal time. The study demonstrates the utility of using subjective driver acceptance ratings to inform the design of active safety systems and to leverage expensive field operational test data within the confines of the laboratory. A real-life example taken from an introductory workshop presentation of this course at a Student National Medical Association meeting is presented to illustrate the student-oriented application of the concepts.

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Patients who underwent bariatric surgery at our center were followed prospectively. Fluorescent in situ hybridisation with group-specific DNA probes, real-time PCR using L. The GAR motif of 53BP1 is arginine methylated by PRMT1 and is necessary for 53BP1 DNA binding activity. Four subjects were measured four times during a treatment protocol. With the systematic functional annotation provided by the Gene Ontology the information required to automate the interpretation task is now accessible.

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The classical complement pathway (CP) activity (CH50) of sera of 13 animal species was compared by parallel assays using rabbit erythrocytes sensitized with immune antibody (RaE-Ab) and sensitized sheep erythrocytes (ShE-Ab). In addition, the bromine incorporation was also found to be highly dependent on the chlorine dosage and the bromide to ammonia ratio. At 300 mg/kg, maternal toxicity including increased clinical signs, suppressed body weight, decreased food intake, and increased weights of adrenal glands, liver, kidneys, and brain were observed in dams. Report of the ad hoc committee of the American Electroencephalographic Society on EEG Criteria for determination of cerebral death. Little is known about how patterns of cell types are organized to form brain structures of appropriate size and shape. Serial radionuclide imaging during treatment of patients with diffuse bone metastases from carcinoma of the prostate. But, compared with 10(-4) M dexamethasone, topical GC at 10(-4) M were significantly more effective at inducing apoptosis in both PBMC and Jurkat T-cells. Furthermore, osteochondral bilayered scaffolds could also be developed. For example, pyrithiamine pyrophosphate (PTPP) binds the TPP riboswitch controlling the tenA operon in Bacillus subtilis.

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Cardiac index and QRS duration were improved by BDOO compared with CDOO. In general, patients referred for elective cosmetic surgery did not present with significant levels of dysfunction. The COMS was a set of multicenter, multidisciplinary randomized clinical trials conducted to evaluate radiotherapy for initial treatment of choroidal melanoma, a primary eye cancer. The aim of the present study was to compare patient compliance with antihypertensive drugs as measured by two methods, electronic monitoring versus refill compliance. In a biotin prototroph, the bir mutation causes overproduction and excretion of biotin, and derepression of at least one biosynthetic gene (bioD). Hydropic changes in the liver occurred in animals receiving doses of 160 mg per kg of body weight per day by the fiftieth day of treatment, but did not occur at lower doses. Follow-up continued for a year after therapy and no patient failed treatment or relapsed. Medication documentation in a primary care network serving North Carolina medicaid patients: results of a cross-sectional chart review. Many human developmental abnormalities and syndromes are determined by defective genomic imprinting.

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Degradation of haemoglobin to bilirubin in the kidney of the dog. Deficient recovery from potentially lethal damage in some gamma-irradiated human fibroblast cell strains. These cells became quiescent in G0/G1 phase and accumulated a hypophosphorylated form of retinoblastoma. The magnitude of changes in IL-1 beta and TNF-alpha production was similar (parallel stimulation or depression) while diminished TNF-alpha was observed simultaneously with enhanced IL-6 production and vice versa. The butterfly rash and the presence of lymphopenia were predictors of decreased survival, whereas the presence of DNA antibodies had no predictive value for survival. Our findings provide strong evidence that both very short and very long telomeres are associated with increased risk of colorectal cancer.

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These differences occur mainly in the heavy fraction of placental mitochondria. Changes in the lithium content in rabbit organs and tissues under the influence of x-ray irradiation. These centers constantly get impulses informing about nutrition situation of tissues. Relationships between pain intensity and heart rate variability in patients after abdominal surgery: a pilot study. All but one of the monoclonal antibodies reacted with protein bands with a molecular weight below 126,000, possibly degradation products of the proteinase. TGFbeta signaling pathways of the bone morphogenetic protein (BMP) subclass are essential for dorsoventral pattern formation of both vertebrate and invertebrate embryos. Our results also provide an alternative to achieve a high level of modified recombinant proteins expressed extracellularly.

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The aim of this retrospective study was to investigate the results of T-cell large granular lymphocytic leukemia treatment with fludarabine by assessing the complete hematologic response, the complete molecular response, progression-free survival, and overall survival. Adrenergic activity as a modulating factor in the genesis of myocardial hypertrophy in the rat. The instructions for health informatics programs have been written and a checklist for the site visit committee members is available. Objectives and content of postgraduate orthodontic training in the Netherlands. The development of Amblyomma americanum and Dermacentor variabilis (Acari: Ixodidae) fed on rabbits immunized with tick hemolymph. IL-18 induces monocyte chemotactic protein-1 production in macrophages through the phosphatidylinositol 3-kinase/Akt and MEK/ERK1/2 pathways. Thus, considering the total cost of preparations, commercial sources may be superior to fresh sources in the clinical laboratory setting. All presented with persistent dyspnea, cough, and lung infiltrates.

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Interleukin-8 haplotype structure from nucleotide sequence variation in commercial populations of U.S. The interface between prosthesis and bone was measured digitally with a specially designed software. Inhibition of human antigen-induced lymphoblastoid B-cell function by an in vivo-induced suppressor T cell. The localization of bypass tracts in the Wolff-Parkinson-White syndrome from the surface electrocardiogram. To determine the type and rate of disability at 2 years of age in infants born in the geographically defined population of East Anglia with a birthweight less than 1500 g and to assess the risk factors for disability. The second part of the study tested the involvement of mixed lineage kinases (MLK) as upstream activators of the JNK pathway in colchicine toxicity, using CEP-1347, a potent MLK inhibitor. The largest difference in treatment outcome occurs between those with no prior treatment and those who have been treated before. Cimetidine inhibition of theophylline elimination: the influence of adult age and the time course. New national guidelines promoting educational quality in ECT visits and protecting the diversity of regionalisation should be implemented. There is little prior study of major dietary patterns and breast cancer survival.

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AL, myeloblastic or lymphoblastic according to age are 16 to 20 times more frequent in Down Syndrome (DS) children than in non DS children. Effect of verapamil on normal sinoatrial node function and on sick sinus syndrome. Gene expression also decreased from a leader peptide point mutant but to a lesser extent. Effect of thyroxine on oxygen consumption of the white rat in the course of post-natal development. Their occurrence should be taken into consideration in the treatment of female gonorrhoea with concomitant adnexitis.--A recommendation is made to the effect that abdominal gonorrhoeal cultures should be prepared in all cases of laparoscopy or laparotomy for acute adnexitis. A prospective investigation of 114 pregnant women compared 54 with consistently negative oxytocin challenge tests to 60 women who did not have oxytocin challenge tests but did have fetal monitoring during labor. Lectin-like oxidized low-density lipoprotein (oxLDL) receptor-1 (LOX-1) was originally identified as a receptor for oxLDL predominantly expressed in endothelial cells. However, at the level of individual glomeruli, dendritic terminals of larval-born Kenyon cells innervate about six glomeruli, apparently randomly. Three phase 3 trials in nonsmall cell lung cancer (STELLAR 2, 3, and 4) have completed enrollment and results are expected in 2005. The clinical progress over 2 years showed a good course without bone resorption.

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Moreover, one study reported that Staphylococcus aureus is common in patients with persistent chronic rhinosinusitis after endoscopic sinus surgery. The subject was asked to follow the vergence target while the configuration of the background target was randomly changed among four conditions in each experiment: the length (experiment 1) or the width (experiment 2) of the horizontal and vertical lines composing the cross of the background target was each randomly changed among four conditions. Crash statistics and simulations are used to max xanax dosage per day predict the effects of design and policy changes on occupant crash safety, and discrete choice experiments are conducted to estimate the values consumers place on vehicle attributes. Synergistic in vitro interactions between (22S,23S)-3beta-bromo-5alpha,22,23-trihydroxystigmastan-6-one and acyclovir or foscarnet against herpes simplex virus type 1. However, the mechanisms involved in the reinforcing properties of MDMA are still unclear.

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The question addressed in this paper is: do such children still profit from orthoptic and surgical treatment?. Prohemorrhagic and bleeding time activities of recombinant tissue plasminogen activator, heparin, aspirin, and a glycoprotein IIb/IIIa antagonist. We report the fabrication and characterization of light-emitting transistors incorporating individual cadmium selenide (CdSe) nanocrystals. Despite the noteworthy migration rate, FCSEMSs should be considered effective for refractory benign biliary strictures. Using primers designed from the terminal sequences of maize rough dwarf virus S6, a 2.2 kb cDNA fragment was amplified by RT-PCR from maize plants showing maize rough dwarf disease. A prospective study of serum C-reactive protein and colorectal cancer risk in men. A total of 40 patients with HGPIN were randomized into 2 groups: one received 4 mg lycopene twice a day for one year, and the other was periodically followed up. However, cyclophosphamide is also an immunostimulator and, on the basis of its known characteristics, could enhance cell-mediated immunity either by modulation of suppressor cell activity or by depletion of infection-induced suppressor cells. Identification of relevant prognostic histopathologic features in 69 intracranial ependymomas, excluding myxopapillary ependymomas and subependymomas. Thus, ClC-2 disruption entails the death of two cell types which depend on supporting cells that form the blood-testes and blood-retina barriers.

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These results suggest that in trained horses, the N:L ratio is a sensitive indicator of stress of short duration, and an attenuated N:L response can be taken as an indicator of adaptation to exercise stress. An implantable, optical oxygenation zetia and perfusion sensor to monitor liver transplants during the two-week period following the transplant procedure is currently being developed. Apart from relative quantification of different intra uterine developmental stages, the assay allows quantitative binding of lectins and antibodies to each of the intrauterine stages. Management of newly diagnosed patients with epilepsy: a systematic review of the literature. A number of studies among the peoples of tropical Africa have shown exceptionally low electrolyte levels. These neurons with vacuoles increased gradually in number and degenerative neurons were also observed by day 14. After treatment of the infection and in cases of MRSA carriage, MRSA is found on the skin and in the nose. There were no other symptoms, and signs indicating hyperthyroidism and proximal myopathy of lower limbs was the isolated clinical feature. Concurrent with poorer performance, schizophrenia patients exhibited hypoactivity within prefrontal brain areas during planning.

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Several indices characterizing the nature of the injuries were analyzed and were found not to be altered significantly when the prophylactic braces were used. Platelets play a crucial role in the physiology of primary hemostasis and pathophysiological processes such as arterial thrombosis. The effect of neonatal administration of zearalenone on the female reproductive system was studied in the rat. Fluid and solute transport in CAPD patients before and after permanent loss of ultrafiltration capacity. After transfer into nutrient medium, those cells produced less coagulase than the non-starved ones. The authors have had the opportunity of making a complete and precise dissection of newborns with congenital dislocation of the hip. Acceptability of exclusive breast-feeding was low in this urban population. Construction and properties of a ribosome-binding site mutation in gene E of phi X174 bacteriophage.

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In the variable pressure scanning electron microscope (VP-SEM) the incident electrons pass through a gaseous environment and the beam is scattered by these interactions. The latter was traced to an inhibition of the FDA assay by jet fuel biodegradation products. Adult blood pressure and climate conditions in infancy: a test of the hypothesis that dehydration in infancy is associated with higher adult blood pressure. The clinical and histological manifestations of leprosy are known to be closely correlated with the immunological state of the patient, which determines prognosis and constitutes the natural basis for the classification of this disease. Increase in c-Fos expression in left nodose ganglion neurons confirms the afferent transmission of the signal (generated by MS) from periphery to the brain by the vagal nerves. Observation on therapeutic effect of point-through-point acupunture on strephenopodia after apoplexy. This mechanism, common in whiplash injuries, could lead to irreversible overstretching or rupture of the ligaments especially as the ligaments consist of mainly collagen fibers. Despite growing interest in evidence-based hospital referral for selected surgical procedures, there remains considerable debate about which measures should be used to identify high-quality providers. blood, urine, cerebrospinal fluid, synovial fluid, vitreous humor, and in tissue samples. A cerebral blood flow computer for use in the angiogram theatre.

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Patients were followed up for a mean of 7 yr and the association between BMI and FFMI and mortality was examined taking age, sex, smoking, and lung function into account. A plea for early recognition of late vascular prosthetic failure. On the other hand, there was no variation in expression of COX-2 in the adenomyosis group during the glucophage xr 1000 mg price in malaysia menstrual cycle, and it was lower than that in the endometriosis group in all phases. The types of rheological blood properties, related to the character of the stroke are described. Authors strongly believe that the future of mammalian oocyte and embryo cryopreservation will be mainly based on vitrification, and the rate of advancement will be determined by the rate by which embryologists learn and acknowledge this new approach. Analyses using peroxisome biogenesis mutants and the whole-scale sequencing projects among several organisms revealed the existence of essential factors responsible for peroxisome biogenesis such as peroxins.

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In this paper, we outline the major strategies for reducing dietary P in different species, review the literature on the impact of these approaches on P forms in manures and amended soils, and discuss the potential beneficial effects on animal agriculture and the environment. Using the differential expression of two unique fluorescent proteins that are expressed under specific conditions, we have developed a real-time assay for macrophage infections. Respiratory stimulants and sleep periodic breathing at high altitude. We also examined the imaging features in patients with paraffinoma, a later complication of these injections. Procalcitonin methotrexate dosage psoriasis as a diagnostic aid in osteomyelitis and septic arthritis. Prostaglandin-producing suppressor cell activity was significantly increased in patients with progressive systemic sclerosis (p less than .01). UK and European legal and regulatory documents and directives are used as the framework for discussion of the current status and future prospects. Two new dihydrocoumarin derivatives, compounds 1 and 2, were isolated from Aloe vera.

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A systematic review of the efficacy and safety of these agents, as both monotherapy and in combination with mood stabilisers, was performed to establish the evidence for their use. To determine what contributes to the professional fulfilment of registered nurses. Estimation of its planarity by the calculation of a distortion coefficient. The lower abdominal transverse rectus abdominis myocutaneous flap for breast reconstruction. In patients with severe emphysema, LVRS, but not continued optimal medical therapy, results in improved sleep quality can prometrium capsules be inserted vaginally and nocturnal oxygenation. The standard operation is based on thoracotomy or dual cervicotomy/thoracotomy, but these approaches do not provide optimal control of the subclavian vessels. A user-friendly web-portal was built that enables dynamic querying of the spatial databases to provide relevant information. To investigate TPE in normal mammalian cells, we developed clones of mouse embryonic stem (ES) cells that contain single-copy marker genes integrated adjacent to different telomeres.

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