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Nipidin (Nifedipine)

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Nipidin is used to treat hypertension (high blood pressure) and angina (chest pain). Nipidin is in a class of drugs called calcium channel blockers. Nipidin relaxes (widens) your blood vessels (veins and arteries), which makes it easier for the heart to pump and reduces its workload.

Other names for this medication:
Anpect, Atenerate, Buconif, Cardifen, Cisday, Coracten, Corotrend, Depicor, Menoprizin, Nidilat, Nidipine, Nifecard, Nifedate, Nifedicor, Nifedin, Nifedine, Nifedipine, Nifehexal, Nifelong, Nifestad, Niften, Nilol, Pressolat, Sidalat, Tredalat

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Also known as: Nifedipine


Nifedipine is used alone or together with other medicines to treat severe chest pain (angina) or high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled.

Nifedipine is a calcium channel blocker. It works by affecting the movement of calcium into the cells of the heart and blood vessels. As a result, nifedipine relaxes blood vessels and increases the supply of blood and oxygen to the heart while reducing its workload.

This medicine is available only with your doctor's prescription.


Nipidin should be taken orally with or without food. It is better to take Nipidin at the same time every day. Take on an empty stomach. Avoid grapefruit juice during treatment with Nipidin. If you want to achieve most effective results do not stop taking Nipidin suddenly.


If you overdose Nipidin and you don't feel good you should visit your doctor or health care provider immediately.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Nifedipine dosage information

Side effects

The most common side effects associated with Nipidin are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Appropriate studies have not been performed on the relationship of age to the effects of nifedipine in the pediatric population. Safety and efficacy have not been established.

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The WFH is also involved in fostering discussion on key issues such as safety and supply of blood products. In 5 of 8 px chicks, these later response peaks were either grossly abnormal in terms of amplitude and latency (including amplitude input/output functions) or often entirely absent. UNIFIED analytical formulation of thin-film radiative properties including partial coherence. Results of thyroid surgery at a high volume centre are satisfactory with very low rates of recurrent laryngeal nerve and parathyroid injury. Heparin inhibition of antibody-dependent complement-mediated lysis. A clinico-electrophysiological characteristic of 56 children with the hemiatrophy syndrome is presented. Traumatic death from rival gang violence in Rivers State, Nigeria. Implant-supported restorative treatment continues to revolutionize all aspects of dentistry.

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We describe the use of a surface electrode attached to a double-lumen endobronchial tube to identify and monitor the recurrent laryngeal nerve during esophagectomy in single-lung ventilation. In addition to this, fungal spoilage/pathogens are causing losses of marketable quality and hygiene of foodstuffs, resulting in major economic problem throughout the world. BD750 significantly inhibited mouse and human T cell proliferation, stimulated either by anti-CD3/anti-CD28 monoclonal antibodies or by an alloantigen, in a dose-dependent manner in vitro. Latent learning in a radial arm maze following neonatal dopamine depletion. Through this mechanism, amphetamine may enhance phasic release of dopamine, which is important in the neural processing of reward. Active proton uptake in lipid vesicles reconstituted with the purified yeast plasma membrane ATPase. P wave changes during exercise in normal subjects and in patients with hemodynamic evidence of left atrial overload.

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We report that deletion of YKU70 or YKU80 suppresses mec1Delta, but not rad53Delta, lethality. A profile of 314 Americans graduating form foreign medical schools. Limited evidence exists to support a causative relationship between reflux and any otorhinolaryngological condition or the effectiveness of treatment. Diphtheria toxin (DT) binds to the EGF-like domain of the DT receptor (DTR), followed by internalization and translocation of the enzymatically active fragment A into the cytosol. In addition, it appears that clindamycin-gentamicin is more efficacious than cefoperazone.

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Intracerebroventricular administration of recombinant CART peptide decreases food intake and CART mRNA levels in the Arc are regulated by leptin. In this study, 2 of 5 of the patients with ICD-10 diagnosis R42 (dizziness and giddiness) had BPPV. No immunoglobulin-containing cells or anti-staphylococcal antibody production was detected in lymph draining either type of lesion. With a concentration of 4 nmol/L, at one hr and 24 hr after SAL treatment, there was no change in mdr-1 mRNA expression, and the IC(50) of gemcitabine was 121.36 micromol/L and 121.64 micromol/L, respectively. Numerous eosinophilic intracytoplasmic inclusions were present in the epithelium of multiple organs, including the pancreatic ducts. The purpose is to report our experience and results in the management of liver hydatid disease.

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Oocyte maturation and fertilization initiates a dynamic and tightly regulated process in which a non-dividing oocyte is transformed into a rapidly dividing embryo. Does heterozygous beta-thalassemia confer a protection against coronary artery disease?. Ultrastruct of the hypothalamic neurosecretory nuclei of the dormouse (Eliomys quercinus L.) in the awakening and hibernating states. Guided by the finding that family-based interventions confer benefit in the treatment of anorexia nervosa in adolescents, we developed a cognitive-behavioral couple-based intervention for adults with anorexia nervosa who are in committed relationships that engages both the patient and her/his partner in the treatment process. The model, which is supported in the literature, posits that fear of pain interferes with recovery because it leads to avoidance of beneficial activity. In this article we present the process we have developed for both analyzing and prioritizing large sets of data starting from diversity and focused uHTS in support of lead generation and secondary screens supporting lead optimization.

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The aim of this study was to assess the influence of nine NSAIDs on the antiplatelet effect of aspirin. It is a major cell surface glycoprotein that is synthesized by cultured fibroblasts, but is not collagen. Although the LS group in this study had a significantly better long-term outcome than the OS group, further investigations are needed to draw a definitive conclusion. Recombinant protein ocular delivery requires invasive and painful repeated injections. A unique axis system has already been defined to enable such measurements to be carried out. Diffuse cerebral sclerosis, melanoderma and adrenal insufficiency (adreno-leukodystrophy). While not excised by exon 2 alone, intron A was efficiently excised when exon 3 and/or exon 4 was combined with exon 2, suggesting the presence of exonic splicing enhancers (ESEs) in exons 3 and 4. Rapid loss of structural motifs in the manganese complex of oxygenic photosynthesis by X-ray irradiation at 10-300 K. The sodium space and plasma volume in pancreatectomized white rats. The machine has five functions: ultrasonic cleaning, cold or hot water spraying, drying and greasing.

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Identification and characterization of a new hemoglobin variant: hemoglobin Sendagi (beta 42 Phe----Val). Both pregnant and nonpregnant SLE patients had decreased absolute numbers of total lymphocytes, T cells, and their subpopulations, but the proportions of these cells were similar in all four groups. We found that cobalt chloride (CoCl2), a chemical hypoxia agent, reduced the expression of GLT-1 in a time-dependent manner. Chinese migrants could be reached with an outreach campaign, and on-site testing was well accepted. Allosensitized T cells produce soluble factors susceptible to suppress allogeneic proliferation but not to interfere on cell mediated cytotoxicity. The electrotherapy may be used in the laxly as well as spastically paralysed muscle. We performed Kaplan-Meier analyses of all-cause mortality and development of first cardiac morbidity after the diagnosis of BBB, along with matched control group comparisons.

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coli HB101(pCADH100) cell extracts prepared from both aerobically and anaerobically grown cells exhibited an additional protein band with an apparent M(r) of approximately 33,000 on sodium dodecyl sulfate-polyacryl-amide gel electrophoresis which was absent in cell extracts of E. Upon increasing the pH to 6.8, the adsorbed layer is composed of a mixture of CPK dimers (native structure) and intermediates, increasing the film thickness (approximately 2.4 nm). Although the degradation of chlorophyllide has been studied in depth, the metabolic fate of phytol in plants is less clear. Genetic impairment of frontocortical endocannabinoid degradation and high alcohol preference. Two out of three organisational interventions showed a positive effect on anxiety outcomes. The ratio of striatal (99m)Tc-TRODAT-1 binding was calculated as the index of (striatum - occipital cortex)/occipital cortex. In a 6.5 year follow-up study we examined the effects of personality (neuroticism, frustration intolerance, rigidity, melancholic type), adverse life events and chronic difficulties on depressive symptoms in 89 high-risk subjects (HRS, siblings and children of patients suffering from an affective disorder), without any mental illness at wave 1 (T1), and 49 controls without any personal and family history of psychiatric disorder at T1.

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This process was found to be Akt-dependent, and inhibition or overexpression of Akt lead to concurrent changes in EZH2 levels. Carbohydrates mediate sperm-ovum adhesion and triggering of the acrosome reaction. The methanogenic strain 442 was insensitive to 40 mug of monensin but sensitive to 10 mug of lasalocid per ml. Both human and animal models indicate that perinatal methadone exposure produces a variety of short- and long-term neurobehavioral consequences, including disruption of normal development of striatal cholinergic neurons. Gastrin-17 was infused through an arterial catheter for 120 min. The inflammatory response to systemic Burkholderia pseudomallei infection leads to depletion of the natural endothelial modulators protein C, protein S, and antithrombin.

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Studies on the mechanism of selective retention of porphyrins and metalloporphyrins by cancer cells. The specific effect of insulin on ATP change is likely related to a rapid stimulation of the hepatic mitochondrial oxidative phosphorylation. The results allow the selection of biofilm-forming vaginal Lactobacillus strains and the conditions and factors that affect this phenomenon. The head-tail linker protein of bacteriophage T5: genetic and immunological studies. These data were combined with accumulated physiological information on vesicle release, receptor kinetics and voltage-gated ionic conductances, and incorporated into computational models for four cells that are representative of the structural variation within our sample population. Research on ethylene biosynthesis and its regulation provided new insights, particularly on the posttranslational regulation of ethylene synthesis and the feedback from ethylene signal transduction. The influence of endocrine effects of adjuvant therapy on quality of life outcomes in younger breast cancer survivors. The 200-amino-acid repeat (HIN-200) gene family with the hematopoietic interferon (IFN)-inducible nuclear protein encodes highly homologous proteins involved in cell growth, differentiation, autoimmunity, and tumor suppression. The obtained chromatogram indicated the characteristic lipid compositions of the bacteria.

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Th2 polarization of the immune response of BALB/c mice to Ixodes ricinus instars, importance of several antigens in activation of specific Th2 subpopulations. The inflammasome also plays a role in the chronic inflammation of the airways of patients with asthma and chronic obstructive pulmonary disease, as well as in the initiation and progression of the inflammatory process in pulmonary fibrosis. Experimental or functional approaches such as cell marking or in ovo pharmacological treatments are emerging in this species, but recent analyses of early development in this species have primarily concentrated on molecular descriptions. In related work, we have examined differences in the mechanism of focal adhesion formation mediated by the FN-binding integrins alpha4beta1 and alpha5beta1. The development and progression of DPN is due in large part to hyperglycemia but is also affected by insulin deficiency and dyslipidemia. A test routine in order to minimise an artefact in tear meniscus height measurement. This association may not be uncommon in view of the presentation of these three patients to one small pediatric center over a 2 year period, out of a total of four patients presenting with TEC. Furthermore, although BubR1 hypomorphic mice have less aneuploidy than Bub3/Rae1 haploinsufficient mice, they age much faster.

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When compared to Sprague-Dawley rats, Lewis rats showed a reduced c-fos mRNA expression after both stressors in most brain areas, which may be related to the reduced responsiveness of HPA axis and also with other abnormal responses in this strain. Statistical analysis of the residual enzyme activity and the extent of modification indicated modification of one essential histidine residue to be responsible for loss of the catalytic activity of EAC cell GA3PD. Man-in-the-barrel syndrome caused by bilateral intratumoral hemorrhage. NO easily penetrates through cell membrane/lipid bilayers, forms dissociable complexes with these molecules and modulates cellular metabolism and functions. The radiative transfer equation in a coating layer with a not too high concentration of pigment particles, which is attached to a substrate, is resolved in terms of Kubelka-Munk theory and a Mie-scattering model. In this study, we examined the acute exposure of waterpipe smoking on lung inflammation and oxidative stress in mice, and compared that to cigarette smoking. After running strain of Wistar-rats it is provable a small nonsignificant increase of the mean chondrocyte number per tissue area in the weight bearing cartilage of the medial femur condylus. Carcinoma ex pleomorphic adenoma(CXPA), salivary duct carcinoma type, noninvasive. From the numerical calculations and experimental results, it was concluded that a dense copper cluster deposition cannot be achieved without aggregation of TMV templates.

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Mean ICTP and CTX concentrations of both animal species increased the first week after parturition. Killing activity of cytotoxic T lymphocytes stimulated by dendritic cell vaccine loaded with autologous cervical cancer antigen. When the hepatitis B antigen is first adsorbed on a specially prepared metal surface, the subsequent reaction with its specific antibody produces complexes that are visible to the unaided eye. These results show that pregnancy with edema and pure toxemia of pregnancy cause renal tubular damage and this damage is reversible. This new lens may be considered as a safe and effective alternative for use as bandage contact lens. It considers the relationship between perceptions of pain, stress and delayed wound healing with a specific focus on guidance for clinical practice. Molecular and pharmacological characterization of the murine tachykinin NK(3) receptor. Systemic vasculitis is a rare condition that usually takes a chronic and often unpredictable course. Furthermore, common complications associated with distal biceps tendon repair and reconstruction can be avoided with this technique. Using both methods we compared the efficacy of generation 5 PAMAM dendrimers in the targeted drug delivery of methotrexate coupled to the polymer.

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The Hayes-Martin manoeuvre involves ligation of the posterior facial vein and superior reflection of the investing fascia below the mandible to preserve the marginal mandibular nerve. False-positive findings were classified according to importance. The standard of management after acute myocardial infarction (MI) includes beta-blockers and acetylsalicylic acid (ASA). Rabbit electroretinogram during recovery from induced ischaemia. Rarely, oculomotor dysfunction has been described in association with PFS. Paucity of Indian literature on rheumatoid neuropathy creates a lacuna in the critical evaluation and discussion of the subject. Mlvi-1, Mlvi-2 and Mlvi-3 represent three independent logi since there is no homology between them molecular clones that identify them and they map on different rat chromosomes.

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A modified compass gait model incorporating measured inputs was used to estimate the effect of pelvic rotation on reducing the vertical displacement of the COM. In this chapter we will discuss the rationale for developing this novel class of antiplatelet agents and specifically, the two compounds in most advanced clinical development, vorapaxar and atopaxar. MOSAIC is a set of tools for the segmentation of multiple aligned DNA sequences into homogeneous zones. Approaches to disrupt this connection might detrol la 4mg generic be an appropriate means to obtain broad-acting tools to modulate a spectrum of infectious diseases. These data reveal that absence of HSP70 alone can significantly increase ARDS, activation of NF-kappaB, and inflammatory cytokine response.

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MPN values obtained for N(2)-fixing bacteria ranged from 0.4 to 1 x 10 per liter for water collected off the coast of Puerto Rico and from 2 to 5.5 x 10 per liter for Chesapeake Bay water. Optimal conditions for detecting antigen and antibodies in the sera of donors and cardiovascular patients have been chosen. Effect of indomethacin and acetylsalicylic acid (ASA) on peroxidase activity of gastric mucosa of rat. Examples of difficult scenarios are given to illustrate the application of the basic principles. Evaluation of an enzyme immunoassay kit for the qualitative assessment of progesterone in bovine milk samples. Mice repetitively challenged with prilosec interactions with other medication ovalbumin developed peribronchial fibrosis (increased total lung collagen and increased peribronchial trichrome staining) as well as increased thickness of the peribronchial smooth muscle layer. The shifts of electrolyes and radioactive ions in the myocardium during various cardiotoxic interventions and administration of some potassium and magnesium salts. 167Tm was bound to acid mucopolysaccharides and transposed by the acid mucopolysaccharides in the tumor tissues and liver. Protein kinase C mu selectively activates the mitogen-activated protein kinase (MAPK) p42 pathway. To test the validity of the model, genetic approaches are used to alter expression levels of Msg5 and Ste7, two of the proteins that negatively and positively regulate Fus3, respectively.

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Interparticle interactions affecting the stability of sludge flocs. Fortunately, in recent years, a variety of new antifungal agents have become available to treat these infections. Preceding the choice of an advanced eye-controlled aid, eye defects can be detected using two-dimensional aids. Male and female mature rats were divided into three groups and fed on commercial pellets: group (C) was control, group (Li1) was given 2000 mg lithium carbonate/kg of food, and group (Li2) was given 4000 mg lithium carbonate/kg of food. The study of phage relationships enabled two large groups of strains to be distinguished: those not or slightly sensitive to phages and those very sensitive to phages. Four new SNPs were identified, which cause 3 amino acid substitutions in the intracellular domain of the receptor: G/C at position 135 bp (in relation to the total sequence of exon 10) (gln/his), CAG/AAA at 352 bp and 354 bp (gln/lys), and C/A at 641 bp (thr/asn).

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PARTICIPANTS provided with a PDA-based CDSS for NSAID prescribing made fewer unsafe treatment decisions than participants without the CDSS. At 28 days after surgery, ioxaglate, an ionic contrast medium, was intravenously injected at 1.5 mL/min in rats. Clinical application of the system may be possible if technical modifications reduce the exposure dose: the high resolution detector systems of the FD-VCT should be combined with radiation systems that focus the radiation to the area of interest. Administration of dextran sulfate sodium (DSS) up-regulated the expression of TLR4 in the colons of WT mice but not in those of MIF-deficient mice. These properties govern the critical functions of spreading and retention of these gels over the vaginal surfaces. Surface dispersion and hardening of self-assembled diacetylene nanotubes.

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Manual respiration of premature and newborn infants and children. Gas-phase chloride-adducted species are generated by negative ion mode electrospray ionization. Immunoglobulins IgA and IgG levels and Lysozyme-activity were examined in the vaginal fluid of 70 pregnant women and 30 non-pregnant women where microbiological examinations did not detect any pathological microorganisms. Both the xylitol and sorbitol signals showed linearity with dose in the measured dose interval, 0-20 Gy. In this particular patient, there probably was some relationship between the laryngeal lesion and an unexplained malaria-like fever contracted in Algeria 19 years before. Butyrate treatment results in the hyperacetylation of histones, with resultant multiple biological effects including inhibition of proliferation, induction of cell cycle arrest, and apoptosis, in a variety of cultured mammalian cells. 1,7-Dimethyl-1,4,7,10-tetraazacyclododecane (DMC) could hydrolyze double-strand DNA at a concentration of 25microM.

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The nonexponential hydrogen bond lifetime correlation functions have been analyzed by using the formalism of Luzar and Chandler, which allowed the identification of the bound states at the bilayer interface and the quantification of the dynamic equilibrium between the bound and the free water molecules, in terms of time-dependent relaxation rates. Visualizing the generation of memory CD4 T cells in the whole body. RFLP revealed the presence of a single genospecies, Borrelia burgdorferi sensu stricto. Overall, 31 and 21 patients were administered sunitinib and sorafenib, respectively. Prevention of blindness in leprosy and the role of the Vision 2020 Programme.

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Consistent with national data, the non-COAs significantly decreased their drug use during this time, but the COAs did not significantly decrease their use. We have identified mutants that exhibit phenotypes attributable to defects in either Mcs6-activating phosphorylation or in Cdc2-activating phosphorylation. Production of cyclic fatty acids: water as the reaction solvent. Addition of prostaglandin E2 (PGE2) to blood mononuclear cell cultures containing pokeweed mitogen (PWM) enhances plasma cell (PC) differentiation measured by intracytoplasmic immunoglobulin 7 days later. The human monocytic cell line THP-1 was used to evaluate in vitro apoptosis by pamidronate. Reliable short-term memory in the trion model: toward a cortical language and grammar. We detect a conformational exchange process in a region of the protein for which dynamics have also been observed in solution.

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HIV risk behaviors occur in a social context, and it is becoming clear that the earliest and most effective way to intervene is in the context where one initially learns about relationships and behavior--the family. No differences were found between the genotype subgroups as to the frequency of rejection episodes. Implications were discussed in terms of further MDS applications and possible re-evaluation of HIT variables or procedures. Heterogeneous response to biostimulation for U(VI) reduction in replicated sediment microcosms. Animals were given sciatic nerve injections with 0-80 mM doxepin, amitriptyline, or bupivacaine (1.5 mL for histological studies, 0.3 mL for neurobehavioral studies). Adjuvant chemotherapy of breast cancer: is it a xanax drug names direct cytotoxic or has it an indirect hormone effect?.

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Chromatographic fractionation of IL 2-containing supernatant from EL-4 thymoma cells (EL-4 SF) yielded a pool of SF that was enriched for IL 2 activity. Considering only the contributors that could be measured within our standards of acceptable error, the approximate sequential order of main contributors to racquet speed between maximum knee flexion and impact was: shoulder external rotation, wrist extension, twist rotation of the lower trunk, twist rotation of the upper trunk relative to the lower trunk, shoulder abduction, elbow extension, ulnar deviation rotation, a second twist rotation of the upper trunk relative to the lower trunk, and wrist flexion. Furthermore, effects were comparable in the laboratory and in the real world. The women interpreted their interval breast cancer in two ways: that mammography can never be completely certain, or as an experience characterized by shock and doubts about the technology and the conduct of the medical experts. The ultraimmunohistochemical localization of carcinoembryonic antigen (CEA) in breast, gastric and lung tumours at various stages of differentiation showed that CEA is mainly located on well differentiated tumour cells, the subcellular morphometric data of which resembled more those of benign lesions rather than those of malignant tumours. MOG antibody-associated NMO/NMOSD could account for some cases thought previously to be AQP4-seronegative NMO/NMOSD. Two 5-HT(1A) agonists, buspirone and 8-OH-DPAT, had different effects.

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