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Novadee (Calcitriol)
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Novadee

Novadee is used to treat and prevent low levels of calcium and bone disease in patients whose kidneys or parathyroid glands are not working normally. It is also used to treat secondary hyperparathyroidism (a condition in which the body produces too much parathyroid hormone and metabolic bone disease in people with kidney disease.

Other names for this medication:
Admax, Alfacalcirol, Alfarich, Alphadol, Arachitol, Aristrol, Biocal, Calcibest, Calcicare, Calcigra, Calosto, Calvical, Cholical, Dmcal, Duracal, Ikmag, Koncal, Kurecal, Laretol, Qpcal, Ritoca, Rockbon, Roical, Sorvate, Vitalpha

Similar Products:
Luvox, Prandin, Micardis, Pamelor, Artane

Also known as: Calcitriol

Description

Generic Novadee is a synthetic vitamin D analog which is active in the regulation of the absorption of calcium from the gastrointestinal tract and its utilization in the body. The two known sites of action of Generic Novadee are intestine and bone. Generic Novadee receptor-binding protein appears to exist in the mucosa of human intestine. Additional evidence suggests that Generic Novadee may also act on the kidney and the parathyroid glands. Generic Novadee is the most active known form of vitamin D3 in stimulating intestinal calcium transport. In acutely uremic rats Generic Novadee has been shown to stimulate intestinal calcium absorption. The kidneys of uremic patients cannot adequately synthesize Generic Novadee, the active hormone formed from precursor vitamin D. Resultant hypocalcemia and secondary hyperparathyroidism are a major cause of the metabolic bone disease of renal failure. However, other bone-toxic substances which accumulate in uremia (eg, aluminum) may also contribute. The beneficial effect of Generic Novadee in renal osteodystrophy appears to result from correction of hypocalcemia and secondary hyperparathyroidism. It is uncertain whether Generic Novadee produces other independent beneficial effects. Novadee is also known as Calcitriol. Generic Novadee treatment is not associated with an accelerated rate of renal function deterioration. No radiographic evidence of extraskeletal calcification has been found in predialysis patients following treatment. The duration of pharmacologic activity of a single dose of calcitriol is about 3 to 5 days. Generic name of Generic Novadee is Calcitriol. Brand name of Generic Novadee is Novadee.

Dosage

Generic Novadee is available in capsules (0.25 mcg) and liquid form. Capsules must be swallowed whole. Do not crush or chew them. If you are prescribed the liquid form, use as directed. Follow dosing instructions closely. Do not take this medication with mineral oil or magnesium containing antacids which may reduce its effects. Foods rich in vitamin D include: fortified dairy products, eggs, sardines, cod liver oil, chicken livers and fresh-water fish. Vitamin D is also obtained from periodic exposure to the sun. It is important to maintain a well-balanced diet while taking this medication. Calcium supplements may be recommended in addition to this medication. If you want to achieve most effective results do not stop taking Generic Novadee suddenly.

Overdose

If you overdose Generic Novadee and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Novadee are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Problems in children have not been reported with intake of normal daily recommended amounts. Some studies have shown that infants who are totally breast-fed, especially with dark-skinned mothers, and have little exposure to sunlight may be at risk of vitamin D deficiency. Your health care professional may prescribe a vitamin/mineral supplement that contains vitamin D. Some infants may be sensitive to even small amounts of alfacalcidol, calcifediol, calcitriol, dihydrotachysterol, or ergocalciferol. Also, children may show slowed growth when receiving large doses of alfacalcidol, calcifediol, calcitriol, dihydrotachysterol, or ergocalciferol for a long time.

Studies on doxercalciferol or paricalcitol have been done only in adult patients, and there is no specific information comparing the use of doxercalciferol or paricalcitol in children with use in other age groups.

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Bacteriocyte-associated gammaproteobacterial symbionts of the Adelges nordmannianae/piceae complex (Hemiptera: Adelgidae). Surface micromachined electrostatically actuated micro peristaltic pump. The pendulum time of life: the experience of time, when living with severe incurable disease--a phenomenological and philosophical study. Pelvic magnetic resonance imaging revealed a huge mass lesion with extravesical extension in the urinary bladder, and computed tomography scan showed external iliac lympho node metastasis. A new antibiotic, fosfonochlorin, was found in the culture filtrate of four strains of fungi freshly isolated from soil samples. High Fidelity Patient Silicone Simulation was perceived by student participants as a highly effective teaching tool. Pantoprazole administered to beagles from PND 1 for 13 weeks resulted in findings similar to those in adult dogs and juvenile dogs, which showed no increase in severity or progression of ECL hyperplasia. For example, watersheds are often rated as good, fair, or poor with regard to a single stressor or with regard to an index of biotic integrity. We further show that for the more symmetrical nanostructures some of the excitons are dark and that the absorption on-sets, the energy of the lowest exciton, for the different nanostructures show no clear evidence of quantum confinement. The degradation of antibiotic amoxicillin in the Fenton-activated sludge combined system.

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The self-assembly of protein molecules into highly ordered linear aggregates, known as amyloid fibrils, is a phenomenon receiving increasing attention because of its biological roles in health and disease and the potential of these structures to form artificial proteinaceous scaffolds for biomaterials applications. The genus Pseudomonas has gone through many taxonomic revisions over the past 100 years, going from a very large and diverse group of bacteria to a smaller, more refined and ordered list having specific properties. These data suggest that chitosan-modified PHBV scaffold loaded with CB-derived USSCs could significantly contribute to wound repair and be potentially used in the tissue engineering. Multi-site intradermal and multi-site subcutaneous rabies vaccination: improved economical regimens. In addition, the efficient part of the epitopes of proteins is assumed to be the size of dipeptides. The relationship between osteoporosis (OP) and osteoarthritis (OA) is yet unclear.

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Conformationally restricted and conformationally defined tyramine analogues as inhibitors of phenylethanolamine N-methyltransferase. Polyunsaturated fatty acids, cognition and literacy in children with ADHD with and without learning difficulties. Interleukin-17 elicits a proangiogenesis effect on human CECs in vitro by promoting migration and tube formation. albicans under the conditions used in these experiments is mainly through the pathways controlled by the above two regulators and not through the RIM101-dependent pathway. For the MI and peripheral arterial disease subgroups, clopidogrel would be considered cost-effective for a treatment duration of 2 years. The potential values at the transformed electrode positions were calculated by linear interpolation from the stored transfer matrix of the outer BEM compartment triangle net. Attenuated inhibition of medium spiny neurons participates in the pathogenesis of childhood depression.

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The radical formation during wet grinding of alumina was exploited to initiate mechano-chemical polymerization reactions of acrylic acid and acryl amide, respectively. Measuring the damage of heavy metal cadmium in rice seedlings by SRAP analysis combined with physiological and biochemical parameters. The chronic disease control and elderly health at the health centers were not standardized for object disease, patient detection program, target population, service provision, and national support budget was insufficient. In vitro data suggest that persistent Chlamydia become resistant to chronic monotherapy of tetracyclines or rifampin, whereas no such resistance is noted when rifampin is added to antimicrobials that are active against Chlamydia. In particular, a high affinity fluo-4 dextran conjugate was prepared and shown to be functional in brain slices. Structural and functional aspects of the heart ventricle myoglobin of bluefin tuna. We present further evidence for the importance of target cell CypA over CypA packaged in virions, specifically in the context of gp160 pseudotyped HIV-1 vectors.

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An analysis of motility parameters (mean velocity and swimming area coefficient) and distribution of cyprids of Balanus amphitrite in different swimming regions in the vicinity of model surfaces (self-assembled monolayers) is presented. The preclinical combination of lenalidomide with the mTOR inhibitor CCI-779 has displayed synergy in vitro and represents a novel combination in MM. Furthermore, owing to its stereotyped circuitry across a range of species, insights from a variety of species have contributed to an increasingly rich picture of how this system develops. Our findings contribute to elucidate the beneficial effects of green tea and mate tea, here in demonstrated by the antioxidant and antigenotoxic properties presented by these teas. Characterization of a 520 kb deletion on chromosome 15q26.1 including ST8SIA2 in a patient with behavioral disturbance, autism spectrum disorder, and epilepsy. The use of arsenic trioxide (As2O3, ATO) combined with all-trans retinoic acid (ATRA) has recently been reported to induce remission in patients with acute promyelocytic leukemia (APL). This article aims to review the available literature on the use of portfolios. Details of cobalt-catalyzed cross-coupling reactions of alkyl halides with allylic Grignard reagents are disclosed. The disposition and metabolism of a hypnotic benzodiazepine, quazepam, in the hamster and mouse. The subjects were studied on three separate occasions, and pretreatment with dexamethasone was given before each study.

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Micronutrient antioxidant intake in patients with chronic pancreatitis. Meat is a good source of protein, readily available iron, calcium, magnesium, selenium, zinc and a range of B vitamins. BCL2-like 12 (BCL2L12) is a new member of the BCL2 gene family that was discovered and cloned by members of our group and found to be expressed in the mammary gland. Mental incapacity is common in acutely ill medical inpatients, and clinicians tend not to recognise it. Contrarily, IL-4 derived from T lymphocytes, was investigated because it is an immunoregulator that counteracts some aspects of inflammation. The present report further underscores the importance of phosphoinositides for the development of the inferior cerebellum and vermis. Recently a number of neuropeptides have been demonstrated to alter gastric acid secretion after central administration. The method utilizes the normalized cuts algorithm to partition WM voxels based on this similarity function along with a connected component labeling algorithm to ensure spatial compactness. Results of the official inspection of the commercial anti-inflammatory enzyme preparations containing chymotrypsin and trypsin by means of modified NF 13 methods.

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Type 1 pili (F1) of porcine enterotoxigenic Escherichia coli: vaccine trial and tests for production in the small intestine tenormin atenolol mg during disease. The experiments are systematic series of perturbations of cancer cell lines by targeted drugs, singly or in combination. Bones, breasts, and bisphosphonates: rationale for the use of zoledronic acid in advanced and early breast cancer. Morphometric and geometric anatomy of the caucasian orbital floor. solenopsis were repelled by leaves from JA-treated plant, but were not repelled by leaves from SA-treated plants. This study characterizes a Schizosaccharomyces pombe mutant rad62-1, which is hypersensitive to methyl methanesulfonate (MMS) and synthetically lethal with rad2 (a feature of recombination mutants). Conservative management of a myxoid endometrial stromal sarcoma in a 16-year-old nulliparous woman. Survival of Escherichia coli O26:H11 exceeds that of Escherichia coli O157:H7 as assessed by simulated human digestion of contaminated raw milk cheeses.

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Randomized controlled trial for behavioral smoking and weight control treatment: effect of concurrent versus sequential intervention. Mast cell infiltration around gastric cancer cells correlates with tumor angiogenesis and metastasis. The inflammatory response of the TGF-beta1-transgenic mice to LPS was associated with high rates of mortality due to endotoxemic shock, marked by systemic hypotension and hypothermia. Talking to friends and family can serve as an effective way to cope with stress. In this study, SALs showed significant differences when compared with the features observed in subjects without possible asbestos-related pulmonary fibrotic changes.

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The effect of beta 2-adrenoceptor activation on ion-shifts and fatigue in mouse soleus muscles stimulated in vitro. We found that seven of nine Ciona Hox genes are located on a single chromosome with some ordering exceptions, and the other genes, including Evx and Mox, are located on three other chromosomes. The structure of the new compound was elucidated on the basis of spectroscopic methods, including 1D and 2D NMR, and high-resolution MS analysis. Baicalein-6-O-beta-glucopyranuronoside-7-O-beta-glucopyranuronoside and baicalein-6-O-beta-glucose-7-O-beta-glucopyranuronoside were first reported by this study. mRNA regulation of cardiac iron transporters and ferritin subunits in a mouse model of iron overload. Treadmill exercise testing was done before and after additional treatment to standing resting normotension with beta-blocker drugs. In autism, abnormalities of the basal ganglia, in particular the caudate nucleus, are the best replicated findings in neuroimaging studies. However, this law was abrogated in 2001 and was joined to the comprehensive infectious diseases control law, in order to facilitate a prophylactic measure against TB infection and to protect human rights of TB patients. With light microscopy techniques, the differential diagnosis is essentially one of a non-differentiated primary or secondary carcinoma, or of a lymphosarcoma.

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