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Qpcal (Calcitriol)
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Qpcal

Qpcal is a hormonally-active, synthetic vitamin D analog prescribed to treat hypocalcemia, osteoporosis, and the prevention of corticosteroid-induced osteoporosis. Systemic Qpcal is FDA indicated to control hypocalcemia in patients on chronic renal dialysis, secondary hyperparathyroidism in those with chronic kidney disease not yet on dialysis, and hypocalcemia in patients with hypoparathyroidism and pseudohypoparathyroidism.

Other names for this medication:
Actical, Alfabond, Alfacal, Alfarich, Apcical, Aristrol, Bonetuf, Calasto, Calbec, Calcimet, Calcirol, Calcor, Calosto, Calsure, Calvical, Calzem, Carcal, Cholical, Dmcal, Duracal, Koncal, Novadee, Nutribone, Osteobel, Politrol, Primacal, Riecal, Romical, Statbone, Tobalt, Trolec, Vezocal

Similar Products:
Sporanox, Dilantin, Fasigyn, Neurontin, Lamictal, Cialis, Micardis, Sildigra, Allegra, Avana

Also known as: Calcitriol

Description

Generic Qpcal is a synthetic vitamin D analog which is active in the regulation of the absorption of calcium from the gastrointestinal tract and its utilization in the body. The two known sites of action of Generic Qpcal are intestine and bone. Generic Qpcal receptor-binding protein appears to exist in the mucosa of human intestine. Additional evidence suggests that Generic Qpcal may also act on the kidney and the parathyroid glands. Generic Qpcal is the most active known form of vitamin D3 in stimulating intestinal calcium transport. In acutely uremic rats Generic Qpcal has been shown to stimulate intestinal calcium absorption. The kidneys of uremic patients cannot adequately synthesize Generic Qpcal, the active hormone formed from precursor vitamin D. Resultant hypocalcemia and secondary hyperparathyroidism are a major cause of the metabolic bone disease of renal failure. However, other bone-toxic substances which accumulate in uremia (eg, aluminum) may also contribute. The beneficial effect of Generic Qpcal in renal osteodystrophy appears to result from correction of hypocalcemia and secondary hyperparathyroidism. It is uncertain whether Generic Qpcal produces other independent beneficial effects. Qpcal is also known as Calcitriol. Generic Qpcal treatment is not associated with an accelerated rate of renal function deterioration. No radiographic evidence of extraskeletal calcification has been found in predialysis patients following treatment. The duration of pharmacologic activity of a single dose of calcitriol is about 3 to 5 days. Generic name of Generic Qpcal is Calcitriol. Brand name of Generic Qpcal is Qpcal.

Dosage

This section provides information on the proper use of a number of products that contain vitamin d and related compounds. It may not be specific to Qpcal. Please read with care.

For use as a dietary supplement:

Do not take more than the recommended daily amount. Vitamin D is stored in the body, and taking too much over a period of time can cause poisoning and even death.

If you have any questions about this, check with your health care professional.

For individuals taking the oral liquid form of this dietary supplement:

This preparation should be taken by mouth even though it comes in a dropper bottle. This dietary supplement may be dropped directly into the mouth or mixed with cereal, fruit juice, or other food.

While you are taking alfacalcidol, calcifediol, calcitriol, dihydrotachysterol, doxercalciferol or paricalcitol , your health care professional may want you to follow a special diet or take a calcium supplement. Be sure to follow instructions carefully. If you are already taking a calcium supplement or any medicine containing calcium, make sure your health care professional knows.

The dose medicines in this class will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of these medicines. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For alfacalcidol To treat bone disease in kidney patients undergoing kidney dialysis: For oral dosage form (capsules): Adults and teenagers—At first, 1 microgram (mcg) a day. Your doctor may change your dose if needed. However, most people will take not more than 3 mcg a day. For oral dosage form (drops): Adults and teenagers—At first, 1 microgram (mcg) a day. Your doctor may change your dose if needed. However, most people will take not more than 3 mcg a day. For oral dosage form (solution): Adults and teenagers—At first, 1 mcg a day. Your doctor may change your dose if needed. However, most people will take not more than 3 mcg a day. For parenteral dosage form (injection): Adults and teenagers—At first, 1 mcg a day. Your doctor may change your dose if needed. However, most people will take not more than 12 mcg a week. To treat diseases in which calcium is not used properly by the body: For oral dosage form (capsules): Adults and teenagers—At first, 0.25 microgram (mcg) a day. Your doctor may change your dose if needed. However, most people will take not more than 1 mcg a day. For oral dosage form (drops): Adults and teenagers—At first, 0.25 microgram (mcg) a day. Your doctor may change your dose if needed. However, most people will take not more than 1 mcg a day. For oral dosage form (solution): Adults and teenagers—At first, 0.25 mcg a day. Your doctor may change your dose if needed. However, most people will take not more than 1 mcg a day.

For calcifediol To treat diseases in which calcium is not used properly by the body or to treat bone disease in kidney patients undergoing kidney dialysis: For oral dosage form (capsules): Adults, teenagers, and children over 10 years of age—At first, 300 to 350 micrograms (mcg) a week, taken in divided doses either once a day or every other day. Your doctor may change your dose if needed. Children 2 to 10 years of age—50 mcg a day. Children up to 2 years of age—20 to 50 mcg a day. To treat diseases in which calcium is not used properly by the body or to treat bone disease in kidney patients undergoing kidney dialysis: For oral dosage forms (capsules and solution): Adults, teenagers, and children—At first, 0.25 micrograms (mcg) a day. Your doctor may change your dose if needed. For parenteral dosage forms (injection): Adults and teenagers—At first, 0.5 mcg injected into a vein three times a week. Your doctor may change your dose if needed. Children—Use and dose must be determined by your doctor.

For dihydrotachysterol To treat diseases in which calcium is not used properly by the body: For oral dosage forms (capsules, solution, or tablets): Adults and teenagers—At first, 100 micrograms (mcg) to 2.5 milligrams (mg) a day. Your doctor may change your dose if needed. Children—At first, 1 to 5 mg a day. Your doctor may change your dose if needed.

For doxercalciferol To treat an overactive parathyroid gland in patients with kidney failure: For oral dosage form (capsules): Adults—10 micrograms (mcg) three times weekly at dialysis. The doctor may change your dose if needed. Children—Use and dose must be determined by your doctor.

For ergocalciferol The amount of vitamin D to meet normal daily recommended intakes will be different for different individuals. The following information includes only the average amounts of vitamin D. To prevent deficiency, the amount taken by mouth is based on normal daily recommended intakes: For oral dosage form (capsules): For the U.S. Adults and teenagers—5 to 10 micrograms (mcg) (200 to 400 Units) per day. Pregnant and breast-feeding females—10 mcg (400 Units) per day. Children 4 to 10 years of age—10 mcg (400 Units) per day. Children birth to 3 years of age—7.5 to 10 mcg (300 to 400 Units) per day. For Canada Adults and teenagers—2.5 to 5 mcg (100 to 200 Units) per day. Pregnant and breast-feeding females—5 to 7.5 mcg (200 to 300 Units) per day. Children 7 to 10 years of age—2.5 to 5 mcg (100 to 200 Units) per day. Children 4 to 6 years of age—5 mcg (200 Units) per day. Children birth to 3 years of age—5 to 10 mcg (200 to 400 Units) per day. To treat deficiency: Adults, teenagers, and children—Treatment dose is determined by prescriber for each individual based on severity of deficiency. To treat diseases in which calcium and phosphate are not used properly by the body: Adults and teenagers—At first, 1000 to 500,000 Units a day. The doctor may change your dose if needed. Children—At first, 1000 to 200,000 Units a day. The doctor may change your dose if needed.

For paricalcitol To treat an overactive parathyroid gland in patients with kidney failure: For oral dosage form (capsules): Adults—1 to 2 micrograms (mcg) one time per day or 2 to 4 mcg three times a week (not more often than every other day). The doctor may change your dose if needed. Children—Use and dose must be determined by your doctor. For parenteral dosage form (injection): Adults—0.04 to 0.1 micrograms (mcg) per kg no more than every other day during dialysis. The doctor may change your dose if needed. Children—Use and dose must be determined by your doctor.

Overdose

If you overdose Generic Qpcal and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Keep out of the reach of children.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Do not keep outdated medicine or medicine no longer needed.

Side effects

The most common side effects associated with Qpcal are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

It is especially important that you receive the right amounts of vitamins so that your baby will also get the vitamins needed to grow properly. Infants who are totally breast-fed and have little exposure to the sun may require vitamin D supplementation. However, taking large amounts of a dietary supplement while breast-feeding may be harmful to the mother and/or baby and should be avoided.

Only small amounts of alfacalcidol, calcifediol, calcitriol, or dihydrotachysterol pass into breast milk and these amounts have not been reported to cause problems in nursing babies.

It is not known whether doxercalciferol or paricalcitol passes into breast milk. Be sure you have discussed the risks and benefits of the supplement with your doctor.

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Percentage of patients treated within one hour of calling for medical help. To investigate the mechanism that the genistein inhibit the MCF human breast cancer cell. Vitamin B12 deficiency: an unusual cause of falls in the elderly. The developed model prediction capability compared with a number of previous models (i.e. Only one cycle utilizing the late stage of ES (Sd2) resulted in an on-going pregnancy. Following surgery, the motor deficit improved in seven patients, was unchanged in five, and showed a slight transient deterioration in five. Optical slots were used as connection components between the transmitter-receiver processing boards and the backplane board to permit easy and repeatable insertion and extraction of the boards with micrometer precision. An anteriorly directed 1.0-kg force was applied on the buccal surfaces of the maxillary first molars in both a horizontal parallel direction and a 30 degree obliquely downward direction to the functional occlusal plane.

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Eight rats received 3.0 mg/kg D-amphetamine before and saline after sessions. These studies frequently employ a variety of experimental manipulations including brain lesions, temporary neural blockade due to cooling or discrete injections of specific drugs. A fraction of about 80,000 molecular weight was obtained from bile, and by incubation of liver tissue in serum or sodium chloride solution, but not from the serum pool. A guidewire that features a flexible tip with a stable shaft could replace the use of a combination of flexible and stable guidewires and increase the success rate of stricture cannulation while decreasing the procedure time.ClinicalTrials.gov Identifier: NCT 01382680. To assess the variability in risk-adjusted readmission rates among hospitals after colorectal surgery. This study revealed novel genotype-phenotype correlations, including a novel candidate gene, and identified 124 genetic defects within a cohort with IRD . Reactive uptake of an isoprene-derived epoxydiol to submicron aerosol particles.

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These dephasing times turn out to be dependent on the mean level spacing and significantly enhanced as compared with the case of open dots. Within this paper we present the overall methodology, the factors influencing the measurement (sample volume, nature and concentration of the applied liquid, number of successive applications), and the robustness of the method. Orientation-dependent potential of mean force for protein folding. Skeletal unloading alleviates the anabolic action of intermittent PTH(1-34) in mouse tibia what is use of albendazole tablet in hindi in association with inhibition of PTH-induced increase in c-fos mRNA in bone marrow cells. There is a high prevalence of headache disorders in children and adolescents.

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Separate studies have shown that the inward remodeling process requires transglutaminase activation and the polymerization of actin. In none of the patients were the changes on MR scan accompanied by relevant new neurological symptoms or signs. Home visits to neighbourhood mothers by CHWs may be a feasible strategy for enhancing maternal/child outcomes. Sporulation by Bacillus subtilis is a cell density-dependent response to nutrient deprivation. How sociodemographics, presence of oncology specialists, and hospital cancer programs affect accrual to cancer treatment trials.

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Yet the concept of NOS1AP as an inhibitor of nNOS predominates in studies of human disease genetics. The study objective was to examine the associations between cultural values and sexual risk factors among Latino youth. However, there is currently no free open-source software available for this purpose. If no complications developed, CRP levels returned to normal within 7 days in the bacterial meningitis group. We conclude that high frequency ventilation with asymmetric flow profiles applied via tube or mouthpiece might be an effective future treatment of mucostasis.

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