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Sparlium (Diazepam)

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Sparlium is a benzodiazepine (ben-zoe-dye-AZE-eh-peens). It affects chemicals in the brain that may be unbalanced in people with anxiety. Sparlium is used to treat anxiety disorders, alcohol withdrawal symptoms, or muscle spasms. Sparlium is sometimes used with other medications to treat seizures. Sparlium may also be used for purposes not listed in this medication guide.

Other names for this medication:
Almpose, Anxol, Calmpose, Daize, Diaclam, Diaze, Diazepam, Dizapam, Dizep, Elcion, Elpam, Elpose, Imilor, Imlor, Lakpam, Neomesmar, Osopose, Paciquil, Paxum, Placidox, Silprex, Sparlium, Syziral, Valrelease, Vipinta, Zeopse, Zycalm

Similar Products:
Lodine, Zyloprim, Eriacta, Theolair, Catapres, Astelin, Geodon, Imodium

Also known as: Diazepam


{name} (diazepam) is a benzodiazepine (ben-zoe-dye-AZE-eh-peen). It is thought that diazepam works by enhancing the activity of certain neurotransmitters in the brain.

{name} is used to treat anxiety disorders, alcohol withdrawal symptoms, or muscle spasms and stiffness.

{name} is sometimes used with other medications to treat seizures.


Take Sparlium exactly as prescribed by your doctor. Follow the directions on your prescription label and read all medication guides. Your doctor may occasionally change your dose. Never use diazepam in larger amounts, or for longer than prescribed. Tell your doctor if you feel an increased urge to use more of this medicine.

Never share this medicine with another person, especially someone with a history of drug abuse or addiction. MISUSE CAN CAUSE ADDICTION, OVERDOSE, OR DEATH. Keep the medication in a place where others cannot get to it. Selling or giving away this medicine is against the law.

Sparlium should be used for only a short time. Do not take this medicine for longer than 4 months without your doctor's advice.

Do not stop using this medicine suddenly, even if you feel fine. Stopping suddenly may cause increased seizures or unpleasant withdrawal symptoms. Follow your doctor's instructions about tapering your dose.

You will need frequent medical tests.

Store at room temperature away from moisture, heat, and light. Keep track of your medicine. You should be aware if anyone is using it improperly or without a prescription.

Detailed Sparlium dosage information


Overdose of benzodiazepines is usually manifested by central nervous system depression ranging from drowsiness to coma. In mild cases, symptoms include drowsiness, confusion, and lethargy. In more serious cases, symptoms may include ataxia, diminished reflexes, hypotonia, hypotension, respiratory depression, coma (rarely), and death (very rarely). Overdose of benzodiazepines in combination with other CNS depressants (including alcohol) may be fatal and should be closely monitored.


Store at room temperature away from moisture, heat, and light. After you have stopped using this medicine, flush any unused pills down the toilet.

Keep track of the amount of medicine used from each new bottle. Sparlium is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription.

Side effects

The most common side effects associated with Sparlium are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not be treated with diazepam if you are allergic to it. You may not be able to use diazepam if you have glaucoma.

If possible before you receive diazepam, tell your caregivers if you have ever had:

glaucoma; asthma, emphysema, bronchitis, chronic obstructive pulmonary disorder (COPD), or other breathing problems; kidney or liver disease; mental illness, depression, or suicidal thoughts or behavior; heart disease; or if you have recently used alcohol, sedatives, tranquilizers, or opioid medications.

Diazepam may harm an unborn baby, and generally should not be used during pregnancy. However, status epilepticus is a life-threatening condition and the benefit of receiving this medicine to treat it may outweigh any risk to the unborn baby. Tell your doctor if you become pregnant.

It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk.

In an emergency, you may not be able to tell caregivers if you are pregnant or breast feeding. Make sure any doctor caring for your pregnancy or your baby knows you received this medicine.

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A Hox regulatory network of hindbrain segmentation is conserved to the base of vertebrates. To elucidate the coronal plane locations of extraocular muscle (EOM) pulleys following torsional muscle surgery. From October 2007 to April 2013, 87 patients with atrial fibrillation (paroxysmal in 3, persistent in 14, and permanent in 70) underwent the Cox maze procedure concomitant with another cardiac procedure. Patients who had heart failure and preserved systolic function had a similar high risk of adverse outcomes as those with low ejection fractions, and new approaches may mitigate this risk. Gastrointestinal hamartomatous polyposis in Lkb1 heterozygous knockout mice. Turning to circadian rhythms, we examine how models can be used to account for the response of 24h patterns to external stimuli such as light pulses or gene expression, and to predict how to restore the physiological characteristics of altered rhythms.

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The toxicological effect of polyphenols extracted from peanut shells was investigated in animal models. Use of lung resection and voriconazole for successful treatment of invasive pulmonary Aspergillus ustus infection. Using data from the National Longitudinal Study of Adolescent Health (Add Health), analyses were conducted on the sample that took part in the baseline and 1 year follow-up assessment between 1994 and 1996. The relation between the acupoint structures and the clinical therapeutic effects. In conclusion, nordihydroguaiaretic acid could constitute a lead compound in the development of novel therapeutic agents for various types of cancer. RSEM is an accurate and user-friendly software tool for quantifying transcript abundances from RNA-Seq data. Incorporating information about cost-effectiveness into evidence-based decision-making: the evidence-based practice center (EPC) model.

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Effects of soy protein on alcoholic liver disease in rats undergoing ethanol withdrawal. Abnormal (18)F-FDG uptake in marrow, when iliac crest biopsy histology is normal, has no adverse effect on outcomes. To investigate stability of tissue azithromycin levels, an additional group of four rabbits was treated for 24 hours, but corneal tissue was not removed until 24 hours later. A case-control study assessed the risk-factors for food-borne toxi-infections with diarrhoea and vomiting as main clinical picture. At 4-6 days post-ligation, extensive defects in the epithelium were observed, frequently with a sharp demarcation between intact epithelium and exposed connective tissue stroma. One hundred sixty-four subjects of both genders (58 males and 106 females, mean age 42.89 years) diagnosis of dysphonia, divided into three groups according to the type of dysphonia: 87 individuals with functional dysphonia, 35 individuals with organofunctional dysphonia and 42 individuals with organic dysphonia, answered the Brazilian validated version of Voice Symptom Scale (VoiSS) (Escala de Sintomas Vocais - ESV), that consists of 30 questions with four scores: Impairment, Emotional, Physical and Total, and self-assessed their voices as excellent, very good, good, fair or poor. Extraintestinal manifestations of Helicobacter pylori: a concise review. There are insufficient data from nationwide surveys on the prevalence of specific psychotic disorders and associated co-morbidities.

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This article provides a basic overview of the condition, and its pathophysiology, diagnosis, treatment and nursing management, so that effective intervention may be implemented, maximising the chances of patient recovery. Reliability of the Chinese version of the perceived family burden scale. Vernalization is a cold treatment that induces or accelerates flowering and insures that temperate-zone plants will not flower until after winter. Total photolytic synthesis of ( )-androcymbine and ( )-multifloramine. Health benefits of reducing sugar-sweetened beverage intake in high risk populations of California: results from the cardiovascular disease (CVD) policy model. Targets of perioperative fluid therapy and their effects on postoperative outcome: a systematic review and meta-analysis.

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The clinical application of endoscopic laser therapy has expanded recently to include the resolution of various strictures of the gastrointestinal tract and the fracture of gallstones. Hairpin folding dynamics: the cold-denatured state is predisposed for rapid refolding. The sediments were dominated by carbonates and clay minerals, and contaminations with Cd-Cu-Pb-Zn-TOC (total organic carbon) at the historical centre and the industrial site were detected, as well as P and Mo input at the mouth of a small creek, probably from agriculture. He completed his undergraduate training at the University of Edinburgh and is now in the process of completing his specialist training in cardiology. PET/MRI offers higher diagnostic confidence in the discrimination of benign and malignant lesions. Between January 2008 and August 2009, 50 patients with femoral shaft fractures were treated with unreamed or reamed femoral nails in our clinic.

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Biochemical changes in sciatic nerve tissue were ruled out by estimating thiobarbituric acid reactive substances (TBARS), reduced glutathione (GSH) and total calcium levels. However, there is a lack of research evidence from in vivo protracted strawberry consumption studies. Lifestyle changes (nutritional therapy and physical activity) have been shown to reduce the frequency of diabetes in small studies and are being assessed in the NIH-funded Diabetes Prevention Trial. vitripennis, but may also lead to the identification of novel targets for biorationally designed control strategies. Using clinical variables and drug prescription data to control for confounding in outcome comparisons between hospitals. The reduced androgen exposure most likely accounted for the decreased oSDN volume. Along with up-regulation in apoptosis, CXCR3-B signals were associated with a decrease in cellular autophagy with reduced levels of the autophagic markers Beclin-1 and LC3B. This spans how they are undertaken, their use in clinical and research settings, their limitations and standardisation and who can perform them.

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Austrian National CathLab Registry (ANCALAR): cardiac catheterization, coronary angiography (CA), and percutaneous coronary intervention (PCI) in Austria during the year 2011 (Registry Data with Audit including 2012). There are no systematic differences in relationship experiences and sexual behaviors between obese and non-obese black girls. Losartan, an angiotensin II receptor antagonist, is widely used for the treatment of hypertension. This study indicated that computer analysis of aortic atheromatous plaque was useful for selecting patients who had a high risk of postoperative stroke or embolism when receiving on-pump CABG, and for decreasing the incidence of them. These studies have important implications for understanding how ligands and receptors interact and for the future development of malaria interventions. Serum sclerostin levels (determined with an ELISA) were assessed.

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Distinct compositional differences were observed among the clone libraries, which revealed a dominance of phylotypes associated with carbon and sulphur cycling, such as Gammaproteobacteria (Thiohalomonas, Allochromatium, Chromatium, Thiomicrospira) and Alphaproteobacteria (Rhodopseudomonas, Rhodovulum, Paracoccus). All lily pollen sequence data are provided as open access files with suitable tools to search sequences of interest. To do this, we non-invasively estimated local field potentials (LFPs) using the ELECTRA distributed inverse solution and applied non-parametric statistical tests at each brain voxel and for each time point. The aim of the present work was to evaluate possible oxidative and genotoxic effects in workers exposed to paints. Parents and caregivers demonstrated favorable conditions in terms of their perceptions, which can be considered an opportunity to promote hygiene habits in children. Mechanism of non-specific-fistula-in-ano: Hormonal aspects-Review.

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Four patients were shown to have BMTLE through bilateral intracranial electrode implantation. Cardiovascular disease and its relationship with chronic kidney disease. We focused in particular on anal intercourse (AI) as practiced by both nonheterosexual (i.e., gay-identified men and other men who have sex with men) and heterosexual men. Impact of intra-subunit interactions on the dimeric arginine kinase activity and structural stability. After 28 weeks, all rats were subjected to electrophysiological experiments. Associations between indicator density and Giarida presence were observed more consistently than between indicator density and Cryptosporidium presence. For example, the magnitude of mortality attributed to natural enemies may be less important than the timing and consistency of that mortality between seasons. These findings define an emerging developmental framework for the control of vascular tissue specification. There are potential risks of this drug that need to be considered. Reaction of aromatic aldehydes with glyceraldehyde 3-phosphate dehydrogenase.

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RNA recognition motif (RRM) is the most abundant RNA-binding domain, mainly known to involve in regulating post-transcriptional processes like intron splicing, stability and mRNA intracellular translocation. It has been approved as maintenance therapy for stable, moderate to severe COPD, but its efficacy and safety in the management of COPD is uncertain compared to other bronchodilators. Rectal prolapse: an overview of clinical features, diagnosis, and patient-specific management strategies. XCEP2 mRNA is expressed at constant levels until mid- to late- gastrula stages, and then strongly is it safe to drink alcohol while taking lamisil down-regulated at late gastrula/early neurula stages. Anaesthesia with sevoflurane leads to a high prevalence of emergence agitation in paediatric patients. The purpose of this study was to examine and compare menstrual-cycle-dependent topographic changes in the optic nerve head of normally menstruating women with different grades of type 2 diabetes mellitus. The impact of a therapeutic drug monitoring program for phenytoin.

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However, the prevalence of complex (genetic) and untreatable disorders (CVI) has taken its place, as a result of increased survival of preterm and low birth weight children and improved diagnostic possibilities. mutans that showed a range of abilities to form biofilms in vitro. To identify which structural compartment of the motion segment is decisive for increased stability after nucleotomy in vivo, the flexibilities of ovine motion segments were measured after different stepwise reductions at the anterior and posterior spinal column. Based on these and other observations we conclude that the most probable source of response periodicity observed early in development is the domination of inner hair cell output by efferent projections of the olivocochlear bundle, the temporal discharge patterns of which are also periodic. A 45-year-old man noted a tendency to fall to the left side on standing following headache and vomiting. The antinociceptive profiles of strong mu- and kappa-opiate agonists were determined in the tail clip, hot plate (55 degrees C) and tail immersion (48 degrees C and 55 degrees C) tests in mice. Acute rejection is higher in VCA than in any other organ in the field of transplantation, although most episodes are controlled by high-dose steroids and optimization of maintenance immunosuppression. In the present study, we analyzed the distribution of CpG methylation within cccDNA in patient samples and investigated the impact of CpG island methylation on cccDNA-driven virus replication. Detection of galactomannan antigenemia in patients receiving piperacillin-tazobactam and correlations between in vitro, in vivo, and clinical properties of the drug-antigen interaction.

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In this study, using the mouse model, we have isolated the exposure to the peri-implantation period, and we examine the effect of superovulation on placentation and fetal growth. Influence of complement C5 and V beta T cell receptor mutations on susceptibility to collagen-induced arthritis in mice. Routine sterile gloving and contamination rates in blood culture. Risk of surgery has been infrequently stratified for patient subgroups. The delivery of pharmacological compounds to the ventolin hfa albuterol dose injured brain is a huge challenge, which may predispose to drug failure and resistance. Interposing a high fat diet (containing PUFA) between starvation and feeding the inducer diet abolished one-half to two-thirds of the overshoot. However, there is scarce information about the factors associated with inspiratory muscle weakness in these patients. Preference and behavior of lactating dairy cows given free access to pasture at two herbage masses and two distances.

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FeCo Prussian blue analogues, which are known as typical molecule-based magnets, exhibited abrupt conductance switching by applying a high electric field as well as by varying the temperature. The polyomavirus middle T antigen (PyMT) is an oncogene that activates the non-receptor tyrosine kinase, c-Src, and physically interacts with Taz (WWTR1). Pathophysiologic role of oxygen-free radicals in toxic damage of the liver. Mycobacterial lung disease in patients with cystic fibrosis--report of three cases. This system has very strong concentrate ability owing to its integrated micro pre-concentrator, which make the detection of trace components in exhaled air very easy. There are currently no clinically validated biomarkers to detect this cancer at an early stage (cancers independent of HPV status).

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Allelic discrimination of cis-trans relationships by digital polymerase chain reaction: GJB2 (p.V27I/p.E114G) and CFTR (p.R117H/5T). Detection of the proliferated donor cells in bone grafts in rats, using a PCR for a Y-chromosome-specific gene. These include the use of monoclytes, dendritic cells and B-lymphoblastoid cell lines as the presenting cells of antigen delivered by pulsing with exogenous proteins or peptides, or of antigen processed endogenously following transduction with one of a variety of viral vectors. Zebrafish are rapidly becoming an important model organism for studying vertebrate development. The absolute neutrophil count reached a nadir of 418 cells/mm(3) during vancomycin use and returned to normal 7 days after its discontinuation. The patient was discharged on the second postoperative day and recovered uneventfully. Interpretation is more meaningful when the haematologist has adequate clinical data. Any study protonix suspension that compared at least one parameter relating to surgical completeness and/or oncological outcome for DTC was considered. In the second part of the experiment 6 patients with sickle cell anemia were studied longitudinally. The understanding of the organization of cell-cycle events is of the utmost importance to devise effective therapeutic strategies for cancer.

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This study sought to evaluate the association between newly revealed abnormal ankle-brachial index (ABI) and clinical outcomes in patients with significant coronary artery stenosis. We show that this is true in searches for vertically oriented groups of moving dots among horizontally oriented groups (Experiment 1) and in searches for motion-linked groups among nonlinked objects (Experiment 2). Comparison of EQ-5D scores among anthracycline-containing regimens followed by taxane and taxane-only regimens for node-positive breast cancer patients after surgery: the N-SAS BC 02 trial. The depression of release of glutamate from amygdaloid slices could be attributed to glutamate derived from glutamine. The water polarization-transfer technique has been used to study the hydration of microcrystalline proteins, lipid membranes, and plant cell wall polysaccharides, and to derive atomic-resolution details of the kinetics and mechanism of ion conduction in channels and pumps.

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Multiple risk factors and outcomes are associated with vancomycin-related nephrotoxicity. Brazing nonprecious alloys properly, professionally and perfectly. In this study, we examined the distribution of the cannabinoid receptors, CB1 and CB2, and the endocannabinoid-metabolizing enzyme FAAH in first trimester human placenta. ERT was started 40 days before the behavioral tests both in gonadally intact (sham-operated) and OVX mice. Furthermore, paclitaxel binding did not affect the overall exposure of charged groups of human serum albumin, as evaluated by its interaction with an ionic exchange resin. Brain oscillatory correlates of spatial navigation were investigated using blind source separation (BSS) and standardized low resolution electromagnetic tomography (sLORETA) analyses of 62-channel EEG recordings. Treatment methods for the determination of delta2H and delta18O of hair keratin by continuous-flow isotope-ratio mass spectrometry. We further observed that US selectively induced activation of extracellular signal-regulated kinase (ERK) 1/2.

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The establishment of such common factors in the experiments groups is an important step towards defining prognostic criteria for the functionality of motor area based on EMG activity of the distal muscles of the hand. Molecular phylogeny and barcoding of Caulerpa (Bryopsidales) based on the tufA, rbcL, 18S rDNA and ITS rDNA genes. Selection criteria for local excision with or without adjuvant radiation therapy for rectal cancer. Here we report that extracellular melanin is produced by Shewanella algae BrY. We performed an experimental study of differential lung ventilation with different levels of positive end-expiratory pressure (PEEP) settings during thoraco-laparoscopy in anesthetized pigs. The peptide formed a stable triple helix structure, and was subjected to glycation reactions with glucose, ribose and glyoxal. This article describes how knowledge gained through focus groups, Web site searches, and individual interviews were used to develop and improve a health-related Web site. The primary advantage is the potential for individual finger motion from a donor nerve with singular function. A rapid and simple determination of protoberberine alkaloids in cortex phellodendri by 1H NMR and its application for quality control of commercial traditional Chinese medicine prescriptions.

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