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Symmetrel (Amantadine)
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Symmetrel

Symmetrel is an antiviral drug. It is used to prevent and to treat a specific type of flu called influenza A. It will not work for colds, other types of flu, or other viral infections. This drug is also used to treat Parkinson's disease and other movement disorders.

Other names for this medication:
Amantadine, Amantral, Amantrel, Comantrel, Neaman

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Also known as: Amantadine

Description

Amantadine is an antidyskinetic medicine. It is used to treat Parkinson's disease (sometimes called "paralysis agitans" or "shaking palsy") and its symptoms, including dyskinesia (sudden uncontrolled movements). It may be given alone or in combination with other medicines (eg, levodopa) for Parkinson's disease. By improving muscle control and reducing stiffness, this medicine allows more normal movements of the body as the disease symptoms are reduced. Amantadine is also used to treat stiffness and shakiness caused by certain medicines that are used to treat nervous, mental, and emotional conditions.

Amantadine is also an antiviral medicine. It is used to prevent or treat certain influenza (flu) infections (type A). It may be given alone or together with flu shots. Amantadine will not work for colds, other types of flu, or other virus infections.

This medicine is available only with your doctor's prescription.

Dosage

Take this medicine with a full glass of water. If you are taking Generic Symmetrel to treat influenza A, start taking the medication within 24-48 hours after flu symptoms begin. Do not stop taking it suddenly.

Overdose

If you overdose Generic Symmetrel and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Symmetrel dosage information

Side effects

The most common side effects associated with Symmetrel are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

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These studies confirmed that a region of 16 residues of the BID-BH3 peptide is responsible for its strong binding to BCL-w and BCL-x(L). Influences of surface chemistry and swelling of salt-treated polyelectrolyte multilayers on migration of smooth muscle cells. A practical method for quantitation of antibody responses to tetanus and diphtheria toxoids in normal young children. Porcine coronary arteries were sliced into 5-mm rings and treated with different concentrations of human recombinant alpha-defensin for 24 hours. Diabetes and chronic liver disease (CLD) are common long-term conditions in the developed and developing world. We describe the design and present the results of the first year of a population-based study of screening for type 2 diabetes in individuals at high risk of developing the disease. Effects of airway tone and volume history on maximal expiratory flow in asthma.

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Choledochal cyst and dilatation of the bile ducts in infancy and childhood. AVE3085 also prevented the elevation of O (2) (.-) and ONOO(-) levels in coronary arteries exposed to ADMA. To identify transcriptionally active open reading frames (ORFs), predicted by bioinformatics, within RD1 genomic segment of Mycobacterium tuberculosis using reverse transcription-polymerase chain reaction (RT-PCR). Two immunologically related cellobiohydrolases, cellobiohydrolase I (CBH I) and cellobiohydrolase II (CBH II), were purified from Aspergillus ficum. The properties of the Mll promoter may be advantageous for the modification of sucrose metabolism in storage roots. Sequences aligned under different optimality criteria are analyzed using partitioned Bayesian analysis with independent models and parameter settings for each gene region, and the most strongly supported phylogenetic hypothesis is then used to test the hypothesis of two colonizations of the New World by African scincid lizards.

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Major hemoptysis is a potentially life-threatening complication of cystic fibrosis (CF) lung disease. These findings suggest that other patient or provider factors may be responsible. The benzodiazepine receptor partial agonists, bretazenil (Ro 16-6028) and Ro 17-1812, affect saccharin preference and quinine aversion in the rat. Properties of 2,3-Butanediol Dehydrogenases from Lactococcus lactis subsp. Effects of sequence divergence on the efficiency of extrachromosomal recombination in mismatch repair proficient and deficient mammalian cell lines. Evaluation of renal preservation using the isolated perfused rat kidney. When they were transduced with a vector encoding CNTF or MNT, however, cells started expressing GFAP in vitro.

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One of these peptides, a 53-kDa peptide, is produced constitutively and appears to mediate initial attachment to chitin. Many local extractive income-based stakeholders rely directly or indirectly on ecosystem health and are adversely affected when the river does not flow. Spatial orientation of glycoproteins in membranes of rat liver rough microsomes. Investigations with bovine lenses separated into cortex and nucleus, involving different media and incubation periods, indicate that tests on the heat lability of the enzyme phosphofructokinase (PFK) allow early recognition of intra-molecular alterations which lead to changes in the stability. The present study suggests the analysis of moderator effects as a promising way to enhance understanding of trait variables and process control performance. In 54 patients suffering from acute viral hepatitis the indirect solid phase radioimmunoassay (ind-SPRIA) for HBsAg was positive in 9 cases the direct solid phase radioimmunoassay (d-SPRIA) being negative. The progesterone permeation rates through polydimethylsiloxane, two polyether urethanes, a hydroxyethyl methacrylate, a polyether urethan--polydimethylsiloxane blend, and a cellulosic membrane were determined. An A384P/A385Y double mutant showed increased susceptibility toward rhodamine 6G compared to the wild type, and F386A and N99A single mutants showed increased susceptibility to dequalinium compared to the wild type. Further, based upon a target set of the GM-SRO parameters, measured from APT experiments, a Monte Carlo algorithm was utilized to simulate statistically equivalent atomistic systems which, unlike APT data, are complete and lattice based.

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Expression profiles reveal that, in spinach, dihydroflavonol 4-reductase (DFR) and ANS are not expressed in most tissues and organs, except seeds, in which ANS may contribute to proanthocyanidin synthesis. Satellite cells are mitotically quiescent in mature mouse muscle: an EM and radioautographic study. From several lines of evidence (including field micrographs at higher magnifications, Markham rotational analysis, and tilting experiments), two conclusions may be drawn concerning the three-dimensional fine structure of F1-ATPase. Skin fibroblast cells from many patients with laminopathies show a range of abnormal nuclear morphology including bleb formation, honeycombing, and presence of multi-lobulated nuclei. IL-12 DNA as molecular vaccine adjuvant increases the cytotoxic T cell responses and breadth of humoral immune responses in SIV DNA vaccinated macaques. Among the oldest, only respiratory disease influenced quitting attempts. The Sport Motivation Scale for Children: preliminary analysis in physical education classes. Parenteral antibiotic therapy at home: experience of the Hospital Center of Laval University. Nursery rhymes and early language acquisition by mentally handicapped children. Obesity is a significant predictor of periodontal disease and insulin resistance appears to mediate this relationship.

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A case is presented of Capnocytophaga bacteraemia, in a juvenile chronic arthritis (JCA) patient receiving steroids, methotrexate and rituximab. This study suggests that simulated angioscopic trauma of the luminal surface of the canine saphenous vein had no negative effect on early patency. The couples showed improvement as rated both by therapists and observers (rating the videotaped sessions) on the PRP after 40 sessions. Effective temperature and jamming transition in dense, gently sheared granular assemblies. The mode of action for enteral nutrition remains unknown but research efforts have begun to elucidate the complex interaction between nutritional luminal contents, intestinal epithelium, and mucosal immune response.

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No early intervention for the prevention of PTSD for all victims has yet proven effective. The distraction-compression method in the treatment of diaphyseal defect: pseudarthroses of the long bones. Most of the beneficial effects of CR are mediated by improved maintenance of mitochondrial performance in aged individuals. However, the small size of HBCs has so far prevented a comprehensive quantitative characterization of protein hydrogen bonds as a function of the basic thermodynamic parameters of pressure and temperature. Such bias in terms of a preference for certain interacting groups within the active site can be used to select a set of receptor-based pharmacophore constraints, which in turn might be used to enhance the docking procedure.

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Urinary nitrogen and sulfur excretion in dogs under different dietary treatments. Repeatability and reliability of the visual acuity examination on logMAR ETDRS and Snellen chart. The occurrence of a granulomatous inflammation following herpes zoster infection is uncommon and its pathogenesis is unclear. Histopathologic examination indicated spread of the tumor intrasclerally and subconjunctivally. Type 1 diabetes mellitus (T1) is considered to be an immune mediated disease. The death ligand tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) bears high potential as a new anticancer agent, as binding to the death receptors TRAIL receptor 1/death receptor 4 (TRAIL-R1/DR4) or TRAIL receptor 2/death receptor 5 (TRAIL-R2/DR5) triggers apoptosis in most cancer cells. Cell-competition algorithm: a new segmentation algorithm for multiple objects with irregular boundaries in ultrasound images. Mutant mitochondrial helicase Twinkle causes multiple mtDNA deletions and a late-onset mitochondrial disease in mice. The influx of complementary and alternative medicines from the East to the West, or indeed the ongoing colonialization of orthodox Western medicine into other non-western traditions requires multiple paradigms of delivering treatment to be considered simultaneously, side by side. Portal vein stenting to treat portal vein tumor thrombus in hepatocellular carcinoma.

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Structural MRI-based classification: possible contributions to clinical diagnosis of schizophrenia. The elastolytic enzyme matrix metalloproteinase (MMP)-12 has been implicated in the development of airway inflammation and remodeling. Myc-CaP cells have an amplified androgen receptor gene despite no prior exposure to androgen withdrawal and they retain androgen-dependent transgene expression as well as androgen-dependent growth in soft agar and in mice. The purpose of this study was to ascertain the influence of HRT on prognostic factors and outcome of breast cancer. Phenotype at diagnosis had predictive value for disease recurrence with upper gastrointestinal disease being the most important positive predictor. Real-time PCR detection of the effects of protozoa on rumen bacteria in cattle. A total of 512 consecutive hormone-naive patients (173 low risk, 212 intermediate risk, and 127 high risk) underwent brachytherapy for clinical Stage T1b-T2cNxM0 (2002 American Joint Committee on Cancer staging system) prostate cancer. For monitoring the occurrence of IgE antibody specific for novel proteins in genetically modified (GM) foods, ELISA is the most convenient method. Small angle X-ray scattering was used to follow the temperature and pressure induced structural transitions of polydisperse native calf lens alpha-crystallins and recombinant human alphaB-crystallins and of monodisperse yeast HSP26. It remains to be determined whether Woringer-Kolopp disease is a variant of mycosis fungoides (ie, within the spectrum of the cutaneous T-cell lymphomas), a benign reactive process, or a syndrome with various causes.

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Wrist denervation via resection of the distal anterior interosseous nerve (AIN) and the posterior interosseous nerve (PIN) is an effective treatment for chronic wrist pain. Spread of human cancer cells occurs with probabilities indicative of a nongenetic mechanism. The combination of double-outlet right ventricle with complete atrioventricular canal has been particularly difficult to correct, with no surgical successes having been reported until recently. Irradiance formations in zyrtec treatment sinus infection hollow straight light pipes with square and circular shapes. These results indicate that not only propolis but also its botanical origin contains high amounts of flavonoid aglycones and that both of them are useful dietary sources for flavonoids with a potency to prevent dioxin toxicity. It is demonstrated that a window of amplified spontaneous emission (ASE) conditions exist, for which the direction of proton emission is sensitive to the ASE-pedestal preceding the peak of the laser pulse, and that by significantly improving the temporal contrast, using plasma mirrors, efficient proton acceleration is observed from target foils with thickness less than 50 nm. We can conclude that AUBM via coronary sinus is feasible in patients with chronic refractory angina after 1 year follow-up, and it appears to be safe.

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A model for the mechanism of generating the auditory evoked field. Other hearts, subjected to 20 min of ischemia, were reperfused with blood for 40 min. Digital subtraction angiography (DSA) demonstrates the hemodynamic portion of aneurysm domes and vasculature structures and has been considered by many to be the principal technique used for aneurysm diagnosis. The role of oxidative stress in patients with multiple sclerosis (MS) is poorly understood. Pseudorheumatic pains as a presenting symptom of cervical chordoma. Serial bleeding of mice is advantageous for the reduction of animal usage, tenormin 50 mg para que sirve dosing errors, and animal-to-animal variation. Further trials addressing duration of chemotherapy are now warranted, particularly with newer chemotherapy schedules. However, current knowledge on the graviresponse of leaves is lacking.

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The Toxicogenomics Project is a 5-year collaborative project by the Japanese government and pharmaceutical companies in 2002. Factors such as inactivity, poor nutrition, smoking, and depression could contribute to an increased risk of dementia in prisoners. The analysis leads to a procedure to obtain both molecular and thermal diffusion coefficients from transient separation measurements. There is emerging evidence that N-terminal probrain natriuretic peptide possesses several characteristics of an ideal biomarker. Conventionally, these cells are functionally isolated from tissue based on their capacity to adhere to the surface of culture flasks. Patients with heterozygous protein C and S deficiency are treated by intravenous heparin and oral anticoagulant therapy. Physiological and biochemical causes for the change in these parameters are discussed. Improvement of Photorhabdus temperata bioinsecticides production in low-cost media through adequate fermentation technology.

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Effect of thalidomide on cardiac remodeling in chronic heart failure: results of a double-blind, placebo-controlled study. However, in contrast to the increase in mitochondrial mass, mitochondrial DNA (mtDNA) decreased, suggesting that enhanced mitochondrial biogenesis may be not the primary cause of the mitochondrial accumulation. The calculation of spherical harmonic expansion coefficients requires integration over the full sphere and can be a computationally cumbersome and also numerically sensitive (with respect to the integration weights) procedure. We then demonstrate that correct specification of the underlying correlation structure versus incorrectly applying a simpler structure can prevent substantial losses in efficiency in estimation of the regression parameter. At 1 day, endothelial denudation with platelet deposition on the surface was shown by means of SEM. We also discuss chemical strategies for improving performance even further.

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A recursive algorithm for decomposition and creation of the inverse of the genomic relationship matrix. The reference lists of the gathered reports were also manually searched. Absorption of sodium from hypertonic sodium phosphate enema solutions. Left ventricular unloading efficacy of nifedipine (15 cases) and verapamil (14 cases) was tested in hypertensive decompensated patients, through one-month treatment period. The first theme concerns the quality and limited power of studies (particularly treatment trials) that have characterised this field. Tetrasomy 21 in an infant with Down syndrome and congenital leukemia. Mounting evidence indicates that deregulation of apoptosis contributes to the development of human cancers. A retrospective analysis of 102 consecutive primary lung transplants was performed to identify risk factors for poor long-term outcome after lung transplantation defined as graft survival and bronchiolitis obliterans syndrome (BOS) stage I and II. While in vitro cellular and molecular methods are well established, only recently has in vivo molecular manipulation been widely used. The results of cancer screening have shown MR colonography to be superior to the traditional double-contrast barium enema.

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Massive pulmonary embolism (PE) with hypotension developed 9 hours after these procedures. QRS complexes may be evaluated for infarction if supraventricular beats without left bundle-branch block occur prematurely, as part of a supraventricular tachycardia or as escape beats after inhibition of the articifial pacemaker. Opinions about mental illness: hospital differences in attitude for propecia medicine eight occupation groups. For effective audit, clinical indicators are required that are valid, feasible to apply and reliable. We then show that the responsiveness of first position bases to mutation pressure is dependent on the second position base and follows the same decreasing trend through the four columns. A suspension of freeze-thawed mitochondria mixed with purple membranes from Halobacteria was illuminated with visible light.

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The anatomy of the posterior rectus sheath is described to explain why blood tracks into the pelvis when the hematomas enlarge. Our findings provide evidence that DAAE inhibits mast-cell-derived immediate-type hypersensitivity. We confirmed differential expression by real-time PCR and found significant up-regulation of myosin light chain 2 (4.2-fold), type II keratin (1.5-fold), tropomyosin (3.1-fold) and parvalbumin (3.5-fold) in the hatchlings whose parents were exposed to arsenic. Teratogenic effect of Colcemide on embryogenesis of chick embryos. Recent studies have shown that H(2)S is generated in vivo in human and animal organisms and that it participates in many pathophysiological processes.

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Secretory granules of a second mucous cell type are mottled in appearance and show an area of increased electron density near the limiting membrane. Large-area arrays of Pt dots are then produced using nanoimprint lithography with the silicon nanopillar mold. To investigate whether a delay in germ cell development also occurs in trisomy 21, we examined the gonads of 30 fetuses, neonates, and infants with trisomy 21 (19 males and 11 females) for the expression of several immunohistochemical germ cell markers throughout pregnancy and compared them with a series of 46 age-matched controls. Sleep and body weight in diabetes mellitus: a large retrospective analysis from South India. In the self-administration initiation test, animals were exposed to two or three unit doses of aniracetam and references for a total available period of 7 weeks. Hypercholesterolaemia (greater than 260 mg/100 ml, hypertriglyceridaemia (greater than 200 mg/100 ml), and hyperuricaemia (greater than 7 levaquin oral tablet 500 mg mg/100 ml). Docetaxel was administered at a dose of 100 mg/m2 by intravenous infusion every 3 weeks. Asthma and chronic obstructive pulmonary disease (COPD) are important causes of morbidity and mortality worldwide.

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Studies in mouse, zebrafish, and chick point to an essential role for EGF-CFC proteins in the action of nodal albendazole oral suspension ip zentel in tamil /GDF1 signals in the early establishment of the mesendoderm and later visceral left-right patterning. None of the actinomycetes significantly enhanced plant growth over these short-term experiments. CCN2 promoted survival of serum-starved HSC and protected the cells from death induced by blocking the NF-kappaB signaling pathway using Bay-11-7082, a specific inhibitor of IkappaBalpha phosphorylation. The catfish CC chemokine genes were found to be not only highly clustered in the catfish genome, but also extensively duplicated at various levels. The development of the method and investigations on the matrix influence on the MS signal are described in particular. Side effects were minimal and oxitropium bromide is an effective bronchodilator in asthma. Excision and biopsy of the lymph node showed infection due to M.

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