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These studies confirmed that a region of 16 residues of the BID-BH3 peptide is responsible for its strong binding to BCL-w and BCL-x(L). Influences of surface chemistry and swelling of salt-treated polyelectrolyte multilayers on migration of smooth muscle cells. A practical method for quantitation of antibody responses to tetanus and diphtheria toxoids in normal young children. Porcine coronary arteries were sliced into 5-mm rings and treated with different concentrations of human recombinant alpha-defensin for 24 hours. Diabetes and chronic liver disease (CLD) are common long-term conditions in the developed and developing world. We describe the design and present the results of the first year of a population-based study of screening for type 2 diabetes in individuals at high risk of developing the disease. Effects of airway tone and volume history on maximal expiratory flow in asthma.
Choledochal cyst and dilatation of the bile ducts in infancy and childhood. AVE3085 also prevented the elevation of O (2) (.-) and ONOO(-) levels in coronary arteries exposed to ADMA. To identify transcriptionally active open reading frames (ORFs), predicted by bioinformatics, within RD1 genomic segment of Mycobacterium tuberculosis using reverse transcription-polymerase chain reaction (RT-PCR). Two immunologically related cellobiohydrolases, cellobiohydrolase I (CBH I) and cellobiohydrolase II (CBH II), were purified from Aspergillus ficum. The properties of the Mll promoter may be advantageous for the modification of sucrose metabolism in storage roots. Sequences aligned under different optimality criteria are analyzed using partitioned Bayesian analysis with independent models and parameter settings for each gene region, and the most strongly supported phylogenetic hypothesis is then used to test the hypothesis of two colonizations of the New World by African scincid lizards.
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Major hemoptysis is a potentially life-threatening complication of cystic fibrosis (CF) lung disease. These findings suggest that other patient or provider factors may be responsible. The benzodiazepine receptor partial agonists, bretazenil (Ro 16-6028) and Ro 17-1812, affect saccharin preference and quinine aversion in the rat. Properties of 2,3-Butanediol Dehydrogenases from Lactococcus lactis subsp. Effects of sequence divergence on the efficiency of extrachromosomal recombination in mismatch repair proficient and deficient mammalian cell lines. Evaluation of renal preservation using the isolated perfused rat kidney. When they were transduced with a vector encoding CNTF or MNT, however, cells started expressing GFAP in vitro.
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One of these peptides, a 53-kDa peptide, is produced constitutively and appears to mediate initial attachment to chitin. Many local extractive income-based stakeholders rely directly or indirectly on ecosystem health and are adversely affected when the river does not flow. Spatial orientation of glycoproteins in membranes of rat liver rough microsomes. Investigations with bovine lenses separated into cortex and nucleus, involving different media and incubation periods, indicate that tests on the heat lability of the enzyme phosphofructokinase (PFK) allow early recognition of intra-molecular alterations which lead to changes in the stability. The present study suggests the analysis of moderator effects as a promising way to enhance understanding of trait variables and process control performance. In 54 patients suffering from acute viral hepatitis the indirect solid phase radioimmunoassay (ind-SPRIA) for HBsAg was positive in 9 cases the direct solid phase radioimmunoassay (d-SPRIA) being negative. The progesterone permeation rates through polydimethylsiloxane, two polyether urethanes, a hydroxyethyl methacrylate, a polyether urethan--polydimethylsiloxane blend, and a cellulosic membrane were determined. An A384P/A385Y double mutant showed increased susceptibility toward rhodamine 6G compared to the wild type, and F386A and N99A single mutants showed increased susceptibility to dequalinium compared to the wild type. Further, based upon a target set of the GM-SRO parameters, measured from APT experiments, a Monte Carlo algorithm was utilized to simulate statistically equivalent atomistic systems which, unlike APT data, are complete and lattice based.
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Expression profiles reveal that, in spinach, dihydroflavonol 4-reductase (DFR) and ANS are not expressed in most tissues and organs, except seeds, in which ANS may contribute to proanthocyanidin synthesis. Satellite cells are mitotically quiescent in mature mouse muscle: an EM and radioautographic study. From several lines of evidence (including field micrographs at higher magnifications, Markham rotational analysis, and tilting experiments), two conclusions may be drawn concerning the three-dimensional fine structure of F1-ATPase. Skin fibroblast cells from many patients with laminopathies show a range of abnormal nuclear morphology including bleb formation, honeycombing, and presence of multi-lobulated nuclei. IL-12 DNA as molecular vaccine adjuvant increases the cytotoxic T cell responses and breadth of humoral immune responses in SIV DNA vaccinated macaques. Among the oldest, only respiratory disease influenced quitting attempts. The Sport Motivation Scale for Children: preliminary analysis in physical education classes. Parenteral antibiotic therapy at home: experience of the Hospital Center of Laval University. Nursery rhymes and early language acquisition by mentally handicapped children. Obesity is a significant predictor of periodontal disease and insulin resistance appears to mediate this relationship.
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A case is presented of Capnocytophaga bacteraemia, in a juvenile chronic arthritis (JCA) patient receiving steroids, methotrexate and rituximab. This study suggests that simulated angioscopic trauma of the luminal surface of the canine saphenous vein had no negative effect on early patency. The couples showed improvement as rated both by therapists and observers (rating the videotaped sessions) on the PRP after 40 sessions. Effective temperature and jamming transition in dense, gently sheared granular assemblies. The mode of action for enteral nutrition remains unknown but research efforts have begun to elucidate the complex interaction between nutritional luminal contents, intestinal epithelium, and mucosal immune response.
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No early intervention for the prevention of PTSD for all victims has yet proven effective. The distraction-compression method in the treatment of diaphyseal defect: pseudarthroses of the long bones. Most of the beneficial effects of CR are mediated by improved maintenance of mitochondrial performance in aged individuals. However, the small size of HBCs has so far prevented a comprehensive quantitative characterization of protein hydrogen bonds as a function of the basic thermodynamic parameters of pressure and temperature. Such bias in terms of a preference for certain interacting groups within the active site can be used to select a set of receptor-based pharmacophore constraints, which in turn might be used to enhance the docking procedure.
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Urinary nitrogen and sulfur excretion in dogs under different dietary treatments. Repeatability and reliability of the visual acuity examination on logMAR ETDRS and Snellen chart. The occurrence of a granulomatous inflammation following herpes zoster infection is uncommon and its pathogenesis is unclear. Histopathologic examination indicated spread of the tumor intrasclerally and subconjunctivally. Type 1 diabetes mellitus (T1) is considered to be an immune mediated disease. The death ligand tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) bears high potential as a new anticancer agent, as binding to the death receptors TRAIL receptor 1/death receptor 4 (TRAIL-R1/DR4) or TRAIL receptor 2/death receptor 5 (TRAIL-R2/DR5) triggers apoptosis in most cancer cells. Cell-competition algorithm: a new segmentation algorithm for multiple objects with irregular boundaries in ultrasound images. Mutant mitochondrial helicase Twinkle causes multiple mtDNA deletions and a late-onset mitochondrial disease in mice. The influx of complementary and alternative medicines from the East to the West, or indeed the ongoing colonialization of orthodox Western medicine into other non-western traditions requires multiple paradigms of delivering treatment to be considered simultaneously, side by side. Portal vein stenting to treat portal vein tumor thrombus in hepatocellular carcinoma.
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Structural MRI-based classification: possible contributions to clinical diagnosis of schizophrenia. The elastolytic enzyme matrix metalloproteinase (MMP)-12 has been implicated in the development of airway inflammation and remodeling. Myc-CaP cells have an amplified androgen receptor gene despite no prior exposure to androgen withdrawal and they retain androgen-dependent transgene expression as well as androgen-dependent growth in soft agar and in mice. The purpose of this study was to ascertain the influence of HRT on prognostic factors and outcome of breast cancer. Phenotype at diagnosis had predictive value for disease recurrence with upper gastrointestinal disease being the most important positive predictor. Real-time PCR detection of the effects of protozoa on rumen bacteria in cattle. A total of 512 consecutive hormone-naive patients (173 low risk, 212 intermediate risk, and 127 high risk) underwent brachytherapy for clinical Stage T1b-T2cNxM0 (2002 American Joint Committee on Cancer staging system) prostate cancer. For monitoring the occurrence of IgE antibody specific for novel proteins in genetically modified (GM) foods, ELISA is the most convenient method. Small angle X-ray scattering was used to follow the temperature and pressure induced structural transitions of polydisperse native calf lens alpha-crystallins and recombinant human alphaB-crystallins and of monodisperse yeast HSP26. It remains to be determined whether Woringer-Kolopp disease is a variant of mycosis fungoides (ie, within the spectrum of the cutaneous T-cell lymphomas), a benign reactive process, or a syndrome with various causes.