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Unizitro (Azithromycin)
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Unizitro

Unizitro is used to treat certain bacterial infections, such as bronchitis; pneumonia; sexually transmitted diseases (STD); and infections of the ears, lungs, sinuses, skin, throat, and reproductive organs.

Other names for this medication:
Amovin, Amsati, Arzomicin, Azicin, Azicu, Azimit, Azimycin, Azinix, Azinom, Azithrocin, Azithromax, Azithromycin, Azitrin, Azitrix, Azitrom, Azitropharma, Azitrotek, Aziwok, Azomax, Azrolid, Azycyna, Bactrazol, Doyle, Fabramicina, Faxin, Hemomycin, Macromax, Medimacrol, Naxocina, Novozithron, Penalox, Phagocin, Respazit, Sitrox, Talcilina, Thiza, Toraseptol, Ultreon, Unizitro, Zetamax, Zicho, Zifin, Zimax, Zithrin, Zithromac, Zithrox, Zitrocin, Zitrofar, Zitroneo, Zymycin

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Also known as: Azithromycin

Description

Unizitro (Unizitro tablets and Unizitro for oral suspension) contain the active ingredient azithromycin, a macrolide antibacterial drug, for oral administration. Unizitro has the chemical name (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl) oxy]-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-1-oxa-6-azacyclopentadecan-15-one. Unizitro is derived from erythromycin; however, it differs chemically from erythromycin in that a methyl-substituted nitrogen atom is incorporated into the lactone ring. Its molecular formula is C38H72N2O12, and its molecular weight is 749.00.

Unizitro, as the dihydrate, is a white crystalline powder with a molecular formula of C38H72N2O12∙2H2O and a molecular weight of 785.0.

Unizitro is supplied as tablets containing azithromycin dihydrate equivalent to either 250 mg or 500 mg azithromycin and the following inactive ingredients: dibasic calcium phosphate anhydrous, pregelatinized starch, sodium croscarmellose, magnesium stearate, sodium lauryl sulfate, hypromellose, lactose, titanium dioxide, triacetin, and D&C Red #30 aluminum lake.

Unizitro for oral suspension is supplied in bottles containing azithromycin dihydrate powder equivalent to 300 mg, 600 mg, 900 mg, or 1200 mg azithromycin per bottle and the following inactive ingredients: sucrose; sodium phosphate, tribasic, anhydrous; hydroxypropyl cellulose; xanthan gum; FD&C Red #40; and spray dried artificial cherry, creme de vanilla, and banana flavors. After constitution, each 5 mL of suspension contains 100 mg or 200 mg of azithromycin.

Dosage

Use Unizitro as directed by your doctor.

Take Unizitro by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation.

Do not take an antacid that has aluminum or magnesium in it within 1 hour before or 2 hours after you take Unizitro.

Unizitro works best if it is taken at the same time each day.

To clear up your infection completely, use Unizitro for the full course of treatment. Keep using it even if you feel better in a few days.

Ask your health care provider any questions you may have about how to use Unizitro.

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) and away from excess moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Unizitro are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Abnormal liver function, hepatitis, cholestatic jaundice, hepatic necrosis, and hepatic failure have been reported, some of which have resulted in death. Discontinue Unizitro immediately if signs and symptoms of hepatitis occur.

The presence of other medical problems may affect the use of Unizitro. Make sure you tell your doctor if you have any other medical problems, especially: allergy to any macrolide and ketolide antibiotic or liver disease with prior Unizitro use or bacteremia (blood infection) or cystic fibrosis or infections, nosocomial or hospital-acquired or weak immune system or bradycardia (slow heartbeat) or hypokalemia (low potassium in the blood) or hypomagnesemia (low magnesium in the blood)

Not recommended in patients with these conditions: congestive heart failure or diarrhea or heart disease or Heart rhythm problems (e.g., prolonged QT interval), history of or Myasthenia gravis (severe muscle weakness).

Use with caution. May make these conditions worse: kidney disease, severe or liver disease. The effects may be increased because of slower removal of the medicine from the body.

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The rho kinase inhibitor Y-27632 improves motor performance in male SOD1(G93A) mice. Overall, EXT-DCR had slightly better success rates than END-DCR (RR 0.96, CI 0.93-1.00). BAL family members are the only described proteins with both PARP and macro domains, underscoring the potential functional significance of this unique combination. This study aimed to identify lactulose-metabolizing bacteria in the human gut, using in silico and traditional culture methods. Increasing evidence suggests that TLR4 expression by tumour cells promotes tumour progression, but it is unclear whether TLR4 is involved in metastasis. We also have shown that the well-known Saccharomyces cerevisiae sulfite efflux permease Ssu1 is also able to excrete nitrite and nitrate.

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Characterization of cytochrome P450 2D6.1 (CYP2D6.1), CYP2D6.2, and CYP2D6.17 activities toward model CYP2D6 substrates dextromethorphan, bufuralol, and debrisoquine. This enhances the exchange of fluids, solutes and blood gases, and allows rapid redistribution of blood flow during states of stress and high metabolic demand. We use an ab initio mean-field theory of magnetic fluctuations for layered materials based on the first-principles local spin-density functional theory implemented through the screened Korringa-Kohn-Rostoker method. Indigenous Principles of Wild Harvest and Management: An Ojibway Community as a Case Study. There were 5 hypogonadal patients, 9 eugonadal nonvenesected patients, and 8 eugonadal venesected patients. A transient elevation of perfusion pressure was observed initially, and during the course of the experiment the perfusion pressure gradually increased. There was no change in the rise time and the decay phase of the glutamate potential in the presence of TI-233.

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In this selective overview we summarize findings of various EEG, neuro-imaging and blood related studies that have been reported in the Indian Journal of Psychiatry. The probability for a farm to be in the high or low scenario depends, among other, on the high, low or nil vectorial activity for a given period and location and on the period(s) of sensitivity of the animals to the disease. Mmp1 processing of the PDF neuropeptide regulates circadian structural plasticity of pacemaker neurons. Logistic regression revealed a significant association between perceived trust in hospital services to education, subjective well-being, being scared for the life of a loved one and perceived trust in emergency services. Furthermore, combining local anesthetic low dose and opioid low dose may produce a new balance with obstetric management. To determine if minor ailments could be managed by pharmacists offering over-the-counter (OTC) medication, free of charge, to refugees exempt from prescription charges. Diabetic Wistar-Kyoto and diabetic SHR presented high Slc2a4/GLUT4 expression in skeletal muscle, as compared to diabetic Wistar. This technique is relatively easy, safe and cheap, and can be carried out immediately before surgery. Joint space narrowing and osteophytes were graded according to the radiographic atlas of the Osteoarthritis Research Society International.

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Streptococcal toxic shock syndrome complicating a peritonsillar abscess. Characteristics of patients, type of accident, and mortality in a consecutive series of head injuries admitted to a neurosurgical unit. In more recent years, the cellular homologs of Crk (Crk II, Crk I, and CrkL) have been extensively studied, and shown to have critical functions in a wide spectrum of biological and pathological processes that include cell motility, invasion, survival, bacterial pathogenesis, and the efferocytosis of apoptotic cells. Using cellular automata images and pseudo amino acid composition to predict protein subcellular location. This study aimed to investigate how the structural stress distribution in human teeth could be affected by the presence of a graded material distribution often found in nature using the finite element (FE) method. The brevity of the K-PAID-5 represents a major advantage in a practical context in that it may impose a minimum burden upon patients with diabetes. Causes of short stature identified in children presenting at a tertiary care hospital in Multan Pakistan. Transduction of c-kit-positive target cells with viruses displaying mbSCF showed enhanced levels of transduction in comparison with unmodified viruses.

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The expression of tight junction proteins and matrix metalloproteinases (MMPs) (Claudin-5, Occludin, MMP-2, and MMP-9) in microvessels were detected by immunofluorescence and western blot. Activation of iNOS contributes to depressed cardiovascular contractile function to NA at the acute phase of streptozotocin-induced diabetes. Temperature-controlled regioselectivity in the reductive cleavage of p-methoxybenzylidene acetals. haemolytica A1 promoter, plpcat, was created and used to interrupt nmaA and nmaB. Intracellular pH and cell-to-cell transmission in sheep Purkinje fibers. Postprandial disruption of migrating myoelectric complex in dogs. Respondents who had an early start in delinquency were likely to have a faster growth of alcohol-impaired driving over the three waves of BLSYM, which implies that these respondents were likely to have a longer path of alcohol-impaired driving in their transition to adulthood. Mind the gap: training road users to use speed and distance when making gap-acceptance decisions. Food and Drug Administration perspective on negative symptoms in schizophrenia as a target for a drug treatment claim. In contrast, an equivalent mass concentration of HSA does not result in tracer dimerization.

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If confirmed in larger studies these observations have important implications for BPT efficacy as well as safety, particularly with regard to the risk of early carcinogenesis. Heterogeneously Catalyzed Continuous-Flow Hydrogenation Using Segmented Flow in Capillary Columns. An open one-compartment model with first and zero order absorption processes and linear elimination is suitable to characterize the pharmacokinetics of tesamorelin. In the case of velocity profiles, it is shown that there is no backscattering of Dirac electrons. However, the occurrence of peripheral oedema in 4 of the patients necessitated the addition of a thiazide diuretic. However, in the literature, its accuracy and the rate of complications vary. Effect of different sources of ventricular repolarization heterogeneity on the resultant cardiac vectors.

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More recently, the genetic identification of mutations in familial counterparts to the sporadic disorders, leading to the development of in vitro and in vivo model systems, has provided insights into disease pathogenesis. This opinion piece will describe QI and CQI initiatives in the US Cystic fibrosis (CF) population. Transcatheter closure of post-operative residual ventricular septal defect using a patent ductus arteriosus closure device in an adult: a case report. Closely consider finances, staffing when expanding office hours. Does buffered lidocaine decrease the pain of local infiltration?. Outcomes were recorded using survey instruments (Oswestry Disability Index and the 36-Item Short Form Health Survey). The pineal tract courses caudally along the left side of the habenular commissure, and a few fibers penetrate the brain through the caudalmost portion of this commissure. To investigate qualitatively and quantitatively the performance of a programme for managing the child contacts of adult tuberculosis patients in Indonesia. Taurine supplementation in spontaneously hypertensive rats: Advantages and limitations for human applications.

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Twenty patients with NSCP hydrea drug classification matched by sex, type of cleft and within the age range of the patients with VCFS were studied as controls. Inhibition of CCK release by bile salts and up-regulation of CCK receptors by CCK may be the mechanisms responsible for the actions of bile salts on CCK target organs. The resistance gene Ur-13, present in the South African large seeded cultivar Kranskop, has been used extensively in the local breeding program. However, microinjection (0.01-0.04 nmol) of AVP into the nucleus tractus solitarius of anesthetized rabbits caused a rise in blood pressure similar to the response seen after i.c.v. The understanding of the regulation of menstruation is of major basic and clinical interest. The 249(serine)p53 mutation is found less often in the serum of patients with HCC in a region with variable levels of exposure to aflatoxin B(1) than in those with uniformly high levels of exposure, but the mutation does occur in black Africans with presumed lower levels of exposure to the fungal toxin. However, the majority of TLR9-deficient mice and wild-type animals treated with poly I:C and an antibiotic developed disease.

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This study evaluates the effect of adding a specific prebiotic mixture of short chain galacto-oligosaccharides (scGOS)/long chain fructo-oligosaccharides (lcFOS) ratio 9:1 and pectin-derived acidic oligosaccharides (pAOS) to formula feeding on the specific immunoglobulin responses to Haemophilus influenza type b (Hib) and tetanus immunization in healthy non-atopic infants during the first year of life. This study found that there is a significant increase in posterior iris bowing in the accommodated state. Despite this success, many parents question, and a small proportion even refuse vaccination for their children. They need a comprehensive assessment which includes evaluation of the patient in several domains, namely physical, mental, socioeconomic, functional and environmental status. The results demonstrate that different regulatory windows can be achieved using various transregulators or combinations thereof. Effect of acetylcholine on the electrical and mechanical responses of the guinea pig vas deferens to nerve stimulation. Rat family and virus carrying state in hemorrhagic fever with renal syndrome. Hypothesis: the classification of epileptic seizures according to systems of the CNS. In the higher frequency bands centred at 3 and 4 kHz, TEOAE amplitudes were almost insensitive to pressure compensation. Since bactrim antibiotic boys born with congenital UDT are more likely to manifest asthma symptoms, the main aim of this study was to investigate the alternative hypothesis that orl rats have greater AHR to a methacholine aerosol challenge than wild type rats.

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Health situation of the armies in the Crimean war and a document related to this. These results suggest that catfish somatostatin is found only in piscine tissues and that there may be a differential expression of the two somatostatin genes in those tissues. We conclude that I3C can inhibit the growth of NPC in vitro and in vivo by suppressing the expression of CDK and cyclin families. Surgical procedures are still the golden standard option in the treatment of liver cystic echinococcosis. A 56-year-old man with diffuse diabetic macular edema received intravitreal injection of ranibizumab into his right eye. In conclusion, urine IL-18, urine NGAL, and plasma NGAL associate with subsequent AKI and poor outcomes among adults undergoing cardiac surgery.

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This was suggestive of acute suppurative thyroiditis with abscess formation causing compressive symptoms. However, if the OVD is removed, postoperative IOP spikes above 21 mm Hg appear related more to patient factors (eg, predisposition in glaucoma patients) and surgically induced trauma than to the specific long-chain non-cross-linked hyaluronan OVD used. Inhibition of monoamine oxidase modulates the behaviour of semicarbazide-sensitive amine oxidase (SSAO). Nitric oxide can promote cellular injury and increase chondrocyte susceptibility to cytokine-induced apoptosis. Efficient boron removal by using mesoporous matrices grafted with saccharides. Administration of BMP-2 with bisphosphonate best decreased bone resorption and increased new bone formation during non-weight-bearing treatment of ischemic osteonecrosis in a pig model, but heterotopic ossification is a concern. We investigated associations between BPA exposure and in vivo estrogenic gene expression in humans.

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The patient subsequently underwent standard tonsillectomy, which allowed us to examine the histopathology of the tissue that was treated with radiofrequency fenofibrate medication action . Here we present a mini-arc plasma method to produce silicon nanocrystals at atmospheric pressure directly from solid silicon precursors. These results suggest that there are two different aromatic amino acid decarboxylases in Drosophila brains, one that decarboxylates L-dopa and 5-hydroxytryptophan and another that decarboxylates tyrosine. Prevention and treatment of heterotopic ossification after spinal cord injury. ApoJ and apoA-I were both detected in apical regions of uterine and oviduct epithelial cells. Because early illness course and outcome may affect the long-term outcome of schizophrenia-spectrum disorders, it is especially important to address poor outcome in this early critical period. The principles of diagnostic pathology are discussed, with reference to selected diseases, namely: mycobacteriosis, Rift Valley fever, rabies, spongiform encephalopathies, morbillivirus and poxvirus infections, viral encephalitides, West Nile virus infection and chytridiomycosis.

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