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Zoldac (Alprazolam)

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Alprazolam, available under the trade name Xanax, is a potent, short-acting benzodiazepine anxiolytic—a minor tranquilizer. It is commonly used for the treatment of anxiety disorders, especially of panic disorder, but also in the treatment of generalized anxiety disorder (GAD) or social anxiety disorder. It was the 12th most prescribed medicine in the United States in 2010. Zoldac, like other benzodiazepines, binds to specific sites on the GABAA receptor. It possesses anxiolytic, sedative, hypnotic, skeletal muscle relaxant, anticonvulsant, amnestic, and antidepressant properties. Zoldac is available for oral administration as compressed tablets (CT) and extended-release capsules (XR).

Other names for this medication:
Acalm, Alpose, Alpraquil, Alprowon, Alprozam, Altok, Alzocum, Alzom, Alzopam, Anilam, Anlzium, Ateez, Balzam, Calmtec, Cqlam, Deproz, Depten, Endep, Finezol, Golprax, Kaprolam, Kurelam, Morecalm, Onapract, Plxna, Pronext, Propnix, Prozam, Romipraz, Sertamax, Sinozol, Somnirest, Sozox, Tenil, Tenlax, Trapose, Zocam, Zolam, Zolin, Zotam

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Danocrine, Alprostadil, Sildigra, Actos, Eulexin, Neurontin, Imitrex, Duphaston, Cenforce, Paxil

Also known as: Alprazolam


Alprazolam is used to relieve symptoms of anxiety, including anxiety caused by depression. It is also used to treat panic disorder in some patients.

Alprazolam is a benzodiazepine. Benzodiazepines belong to the group of medicines called central nervous system (CNS) depressants, which are medicines that slow down the nervous system.

This medicine is available only with your doctor's prescription.


Take this medication by mouth as directed by your doctor. Dosage is based on your medical condition, age, and response to treatment. Your dose may be gradually increased until the drug starts working well. Follow your doctor's instructions closely to reduce the risk of side effects.This medication may cause withdrawal reactions, especially if it has been used regularly for a long time or in high doses. In such cases, withdrawal symptoms (such as seizures) may occur if you suddenly stop using this medication. To prevent withdrawal reactions, your doctor may reduce your dose gradually. Report any withdrawal reactions immediately.Along with its benefits, this medication may rarely cause abnormal drug-seeking behavior (addiction). This risk may be increased if you have abused alcohol or drugs in the past. Take this medication exactly as prescribed to lessen the risk of addiction.When this medication is used for a long time, it may not work as well. Talk with your doctor if this medication stops working well.Tell your doctor if your condition persists or worsens.


Seek emergency medical attention if you think you have used too much of this medicine. An overdose of Zoldac XR can be fatal.

Overdose symptoms may include extreme drowsiness, confusion, muscle weakness, loss of balance or coordination, feeling light-headed, fainting, and coma.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

It is very important to protect the orally disintegrating tablets from moisture. Remove and throw away any cotton packaging from the medicine bottle when you first use the medicine.

Detailed Zoldac dosage information

Side effects

The most common side effects associated with Zoldac are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.Some products that may interact with this drug include: kava, sodium oxybate.Other medications can affect the removal of Zoldac from your body, which may affect how Zoldac works. Examples include azole antifungals (such as itraconazole, ketoconazole), cimetidine, certain anti-depressants (such as fluoxetine, fluvoxamine, nefazodone), drugs to treat HIV (delavirdine, protease inhibitors such as indinavir), macrolide antibiotics (such as erythromycin), rifamycins (such as rifabutin), St. John's wort, drugs used to treat seizures (such as carbamazepine, phenytoin), among others.Tell your doctor or pharmacist if you also take drugs that cause drowsiness such as: certain antihistamines (such as diphenhydramine), medicine for sleep or anxiety (such as diazepam, zolpidem), muscle relaxants, narcotic pain relievers (such as codeine), psychiatric medicines (such as chlorpromazine, risperidone, amitriptyline, trazodone).Check the labels on all your medicines (such as cough-and-cold products) because they may contain ingredients which cause drowsiness. Ask your pharmacist about the safe use of those products.Cigarette smoking decreases blood levels of this medication. Tell your doctor if you smoke or if you have recently stopped smoking.

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Penalized Cox regression implementing cross-validation was used for covariate selection and modeling. Clinical competence: the use of simulators/models in diagnosis of visceral conditions. The ethylene receptor family of Arabidopsis consists of five members, one of these being ETR1. Behavioral tests of functional deficit were performed at 24 h and weekly thereafter. under-reporting was more frequent among older persons with higher percentage of body fat in both methods of assessment of food intake. Various sociodemographic, clinical, biochemical, and genetic factors were assessed at baseline. Brevisulcatic acids, marine ladder-frame polyethers from the red tide dinoflagellate Karenia brevisulcata in New Zealand. Arteriography demonstrated complex plaque at the aortic bifurcation associated with aneurysmal dilation of the distal common iliac artery in both patients. Secondly, treatment with liposomal MDP-GDP was initiated prior to tumor cell injection and continued after tumor cell injection. Malignant MO4 mouse fibrosarcoma cells were confronted with fragments of hypoblast from stage 4 (Vakaet 1970) blastoderms in different dispositions either permitting or preventing contact of the hypoblast with the tissue culture plastic.

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Novel autonomic neurotransmitters and upper gastrointestinal function. The effect of bombesin on basal, alpha-methyl-p-tyrosine, haloperidol, morphine, bremazocine and stress-induced prolactin secretion. These areas of the brain contain neurons that extend axons into the striatum, suggesting that CNS circuitry may aid the distribution of the gene product. To protect children against infection with seasonal influenza viruses, this age group is vaccinated annually in some countries. This study shows that NEMs, with FLG-KD and/or cultured in the presence of IL-31, mimic the skin of patients with atopic dermatitis in several aspects, including enhanced bacterial colonization, increased inflammatory and reduced protective responses. The derived survey instrument then underwent prospective testing in patients with acute sinusitis, chronic sinusitis, allergic rhinitis, and asymptomatic controls. Gastritis and hypergastrinemia due to Acinetobacter lwoffii in mice. These relations were examined in 112 nonhypercholesterolaemic subjects, of whom 70 consumed 3.8-4.0 g plant stanol esters a day for 8 weeks. Furthermore, we found distributed MOB activity locked to the nasal respiration cycle. Catalytic inhibition was not abrogated by topoisomerase II mutations that totally abolish the effect of bisdioxopiperazine compounds on catalytic inhibition, suggesting a different mode of action by these maleimides.

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A registered dietitian obtained GI, GL and other dietary data from 58 MHD patients. The study interviewed 2,472 elderly individuals 65 years or older without cognitive deficits suggestive of dementia, in probabilistic samples from seven Brazilian cities. Currently little transcriptomic and genomic data are available to understand molecular interactions in the WPBR pathosystem. Although TNF-alpha is one of the iNOS-inducible factors, the iNOS up-regulation was not regulated by TNF-alpha. A geometric interpretation of this observation using the impact ionization mean free path as a quantifier, allows extension of the model to very low energies. Evolution of nutritional status in patients with autologous and allogeneic hematopoietic stem cell transplant. A review of melatonin as a suitable antioxidant against myocardial ischemia-reperfusion injury and clinical heart diseases. The thiol groups thus introduced on the probe surface can then react with the HyA SS-pyridine group, resulting in a covalent bonding of the latter on the former.

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The role of electrodes in the transport properties of molecular devices is investigated by taking C(60) as an example and using gold nanowire and a gold atomic chain as the electrodes. Information is given on modes and sources of infection, organs involved in the disease, prevalence, diagnostics, therapy, and prophylaxis. This study analyzed the nutritional outcomes, clinical morbidity, and mortality of children with EB. Data was obtained from Inter-University Consortium for Political and Social Research (ICPSR) and directly from authors whose data were presented in another way than percentages. We have studied the effect of pressure on the anomalous lattice striction, both in the ab-plane and along the c-axis, of (La,Pr)(1.2)Sr(1.8)Mn(2)O(7) single crystals over the temperature region where the paramagnetic insulator to ferromagnetic metal transition takes place. About half of the members of the Tramtrack group contain a Psq domain, while the other half is made up of proteins that contain a zinc finger domain. The etiologic agent most frequently identified is Staphylococcus aureus, principal emerging pathogen of invasive musculoskeletal infections in otherwise healthy children. The discourse on Black boys tends to suggest that Black boys are in complete peril. This study demonstrated that dyslipidemia exists in our type 2 diabetic population with greater TC in hypertensive type 2 diabetic females compared with hypertensive type 2 diabetic males. T cells from children aged 9-17 with idiopathic uveitis were studied.

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In both cases, biochemical markers later confirmed the diagnosis of myocardial infarction. The major point of this article is to highlight and revisit these aspects for pertinent future use. Sequencing of families with extreme quantitative traits could be an important next step in the dissection of the genetics of type 2 diabetes. Inhibition of influenza A virus replication by RNA interference targeted against the PB1 subunit of the RNA polymerase gene. Kinetics of random sequential adsorption (RSA) of disks on flat, two-dimensional surfaces is governed by a power law with exponent -1/2.

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Analytical and numerical models to explain steady rates of spring flow. The peripheral remodeling seen during development of innervation to the Dorsal Longitudinal (flight) Muscle (DLM) in Drosophila involves an initial retraction of larval neuromuscular junctions followed by adult-specific branch outgrowth. Octreotide is widely used as a prophylactic for postoperative complications in pancreas transplant recipients. Dietary n-3 PUFA decreased the rate of appearance and increased the hepatic clearance of IDL/LDL resulting in a marked decrease in the plasma concentration of these particles. The TEM shows that the composites consist of PANI and TiO(2) nanoparticles. These observations provide a better understanding of the role that periarticular bone has in the degenerative process after hemiarthoplasty.

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Exposure of planulae to exogenous norepinephrine caused premature, rapid metamorphosis and produced polyps with slightly stunted tentacles and pitted, irregular hypostomes. Most of the reported cases of spinal hydatid disease presented with spinal cord compression syndrome. The burden of Hepatitis C virus (HCV) has become more and more considerable in China. There is evidence to suggest that risk assessment for adverse psychological outcomes after traumatic events may be a useful management strategy. Postprocedural 3T-MRA was performed in a cohort of 39 patients undergoing EN stent-assisted intracranial aneurysm coiling. The importance of it lies in that it is a potentially reversible cause of this clinical presentation, unlike its other counterparts, aneurysmal subarachnoid hemorrhage (SAH) or vasculitis. Perthes disease is idiopathic avascular osteonecrosis of the hip in children, with unknown etiology. Findings have translational implications for therapy and vaccine development.

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Effect of acute ethanol ingestion on human gastric luminal prostaglandin E2, prostaglandin F2 alpha and 6-keto-prostaglandin F1 alpha. In this model one of the two end monomers of each polymer chain is fixed in space mimicking dangling chains attachment to a polymer network, while the sticky monomer at the other end of each chain can form pairwise reversible bond with the sticky end of another chain. Failure was defined as thioridazine medication modification or addition of antibiotic due to clinical deterioration, cultured organism resistant to Piperacillin-Tazobactem and Death. Furthermore, we believe that this approach does not compromise the function of the rotator cuff. When the three hormones are given together on top of isoglycaemic intravenous glucose, glucagon suppression is delayed in a manner similar to that observed after oral glucose. Wound repair and anti-inflammatory potential of essential oils from cones of Pinaceae: preclinical experimental research in animal models.

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To analyse the possible effects of these different population sizes, this study compares the variation observed at microsatellite and major histocompatibility complex (MHC) loci in samples of wild western and mountain gorillas, collected using a sampling scheme that targeted multiple social groups within defined geographical areas. Recently two diagnostic options are discussed, serum MicroRNA (miRNA) and serum exosomes. Aspalathin and Nothofagin from Rooibos (Aspalathus linearis) inhibits high glucose-induced inflammation in vitro and in vivo. Therefore, the expression of TLR-9 may differ according to the results of bacterial culture, and thus a change in proinflammatory cytokine induction can also be expected. Aberrant methylation of HIN-1 (high in normal-1) is a frequent event in many human malignancies. This program looked at extended adjuvant therapy options in breast cancer, focusing on adjuvant therapies in women who are postmenopausal with advanced breast cancer and disease progression following traditional antiestrogen therapy. In 6 of 11 previously untreated schizophrenic patients the VEP latency became abnormal following therapy with agents known to cause dopaminergic blockade. Fourteen of the available 15 studies suggest that the development of problems with BE, BED or LOC eating post-bariatric surgery norvasc dosage and route is associated with less weight loss and/or more weight regain post-bariatric surgery. The prognostic value of p53 no longer existed after examination of the surgical specimens (post-radiotherapy). Assessing the Development of Multidisciplinary Care: Experience of the National Cancer Institute Community Cancer Centers Program.

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